Clinical trials: Cholecalciferol
Atopic Dermatitis, Asthma
Vitamin D and Its Receptor Gene Polymorphisms in Lithuanian, Latvian and Taiwanese Patients With Atopic Dermatitis and Asthma
The role of vitamin D is well known in calcium and phosphate homeostasis; however, in addition to traditional functions, vitamin D has an important role in pathogenesis of different allergic diseases, such as asthma, atopic…
- Trial name
- NCT04354207
- Testing
- Peripheral vein punction, Stool collection
- Where
- Lithuania
- Volunteers
- 500 people
- Sponsor
- Lithuanian University of Health Sciences
Knee Osteoarthritis
Zurich Multiple Endpoint Vitamin D Trial in Knee OA Patients
This is a 2-year double-blind randomized controlled trial in 287 community-dwelling individuals age 60 years or older undergoing uni-lateral total knee replacement due to severe OA of the knee.We compare an oral dose of 2000 IU…
- Trial name
- NCT00599807
- Testing
- Vitamin D3 (cholecalciferol)
- Where
- Switzerland
- Volunteers
- 273 people
- Sponsor
- University of Zurich
Allergic Rhinoconjunctivitis
Vitamin D and Grass Pollen Specific Immunotherapy
Allergen-specific immunotherapy is the only causal therapy of Immunoglobulin E-induced allergies like allergic rhinoconjunctivitis.
- Trial name
- NCT01466465
- Testing
- Cholecalciferol, middle-chain fatty acids (carrier)
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- Charite University, Berlin, Germany
Postmenopausal Osteoporosis With Pathological Fracture
Clinical Comparison of Efficacy and Safety of Two Teriparatide Formulations: Osteofortil and Forteo
The primary objective of this study is to compare efficacy and safety of two formulations of teriparatide 20 mcg/day plus calcium and vitamin D in postmenopausal women with osteoporosis.
- Trial name
- NCT01945788
- Testing
- Teriparatide (rDNA origin)
- Where
- Argentina
- Volunteers
- 110 people
- Sponsor
- Bio Sidus SA
Multiple Sclerosis
Step it Up: An Exercise and Behaviour Change Programme for People With Multiple Sclerosis
Exercise has consistently yielded short-term, positive effects on health outcomes in people with multiple sclerosis (MS). However, these effects have not been maintained in the long-term.
- Trial name
- NCT02301442
- Testing
- Exercise + behaviour change intervention, Exercise + control education
- Where
- Ireland
- Volunteers
- 65 people
- Sponsor
- University of Limerick
Recurrent Respiratory Tract Infections
Impact of Vitamin D Supplementation on Recurrent Respiratory Infections in Paediatric Primary Care.
Up to date, some clinical trial have evaluated the efficacy and safety of Vitamin D supplementation in children with RRI, with no conclusive information.
- Trial name
- NCT02617771
- Testing
- Vitamin D3
- Volunteers
- 84 people
- Sponsor
- Policlinico Hospital
Deficiency of Vitamin D3
Study on the Effects of a Recommendation Based Supply of Vitamin D3 in Healthy Volunteers
The aim of this study is to investigate whether a supplementation of 20 µg Vitamin D3 per day for 12 weeks can be used to normalize vitamin d-Status
- Trial name
- NCT01711905
- Testing
- Vitamin D3
- Where
- Germany
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Infant Colic
Lactocare Baby Drops in Infants Colic
The objective of this study is to determine an efficacy of the combination of L. rhamnosus 19070-2 (FloraActiveTM) and L. reuteri DSM 122460 (FloraActiveTM) in decreasing cry/fuss in infants aged 4 through 12 weeks with IC.
- Trial name
- LACONIC (NCT02839239)
- Testing
- Drops with lactobacilli and vitamin D3, Drops with vitamin D3
- Volunteers
- 168 people
- Sponsor
- Biocare Copenhagen A/S
Keratoconus
Thyroid Gland Dysfunction and Vitamin D Polymorphism in Keratoconus
This prospective study the thyroid gland dysfunction and vitamin D receptor polymorphism in keratoconus patients
- Trial name
- NCT05073601
- Testing
- ELISA,DNA extraction
- Where
- Egypt
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Osteogenesis Imperfecta
Effect of High-Dose Vitamin D on Bone Density in Osteogenesis Imperfecta
Overall Objective: To test the hypothesis that oral vitamin D supplementation at higher than currently prescribed doses has a beneficial effect on the skeleton of young patients with osteogenesis imperfecta (OI).
- Trial name
- NCT01713231
- Testing
- standard-dose vitamin D (400IU per day), high-dose vitamin D (2000 IU per day)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Louis-Nicolas Veilleux Ph.D.
Physical Disability
Multi-ingredient Nutrition Supplement in Older Adults
The aims of the present study are: i. To conduct a population study of body composition, muscle function and ability to undertake activities of daily living in elderly Irish individuals ii.
- Trial name
- NCT02001831
- Testing
- Supplement
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Primary Open- Angle Glaucoma
Associations of Vitamin D Receptor ApaI and Tru9I Polymorphisms With the Risk of Primary Open-angle Glaucoma
This study investigated whether vitamin D receptor gene polymorphism is altered in primary open-angle glaucoma subjects carrying the risk allele.Primary open-angle glaucoma patients and age-matched people in the Han population…
- Trial name
- NCT02805231
- Testing
- Vitamin D receptor polymorphic analysis
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lv Yingjuan
Intermittent Fasting, Healthy
Monitoring Intermittent Fasting for Human Optimization Using Wearable Technology: An N-of-1 Study
There is a growing interest in personalized health strategies, including diet, exercise, and fasting regimens, to enhance metabolic fitness.
- Conditions
- Intermittent Fasting, Healthy, Digital Health
- Trial name
- NCT06630637
- Testing
- Glucose-Ketone Index (GKI) monitoring, Continuous Glucose Monitoring (CGM), Digital dynamometer
- Where
- Singapore
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Institute for Digital Medicine (WisDM)
Raloxifene, Postmenopausal Women
Raloxifene on Coagulation System in the Postmenopausal Women
Objective: The aim of this study is to assess the effects of raloxifene HCl on coagulation parameters in healthy postmenopausal women.
- Trial name
- NCT04454775
- Testing
- coagulation system parameters; factor 8, von Willebrand factor, protein C, protein S, antithrombin III and fibrinogen were studied.
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Oxidative Stress, Anesthesia
Comparison of Total Oxidant and Total Antioxidant Capacities in Low-Flow and High-Flow General Anesthesia
The goal of this observational study is to determine whether low-flow anesthesia has a positive contribution to the total oxidant/antioxidant balance.
- Trial name
- NCT05590312
- Testing
- general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Duzce University
Non-Small Cell Lung Cancer
A Multi-Centered Trial Evaluating the Role of Vitamin D Metabolism in Non-Small Cell Lung Cancer
Vitamin D exerts antiproliferative and differentiating effects in cancers, including non-small cell lung cancer (NSCLC). The active form of Vitamin D is 1,25, dihydroxycholecalciferol (calcitriol) which rapidly induces expression…
- Trial name
- EBUS (NCT01409681)
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- University of Michigan Rogel Cancer Center
Infertility
Influence of Serum Vitamin D Levels on Embryo Morphokinetic Parameters
The aim of this study is observing the relation between serum Vitamin D levels and morphokinesis of time lapse monitored Day 5 embryo in between 18 and 38 years age women undergoing controlled ovarian hyperstimulation (COH)…
- Trial name
- NCT02365337
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bahceci Clinic
Alopecia Areata
Comparison of Microneedling Along With Topical Vitamin D3 Versus Microneedling in Alopecia Areata
Alopecia areata is a common condition that causes sudden, patchy hair loss on the scalp and other body sites. It is believed to occur when the body's immune system mistakenly attacks the hair follicles, leading to hair loss that…
- Trial name
- NCT07243977
- Testing
- Microneedling + Vitamin D3, Microneedling
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Sarcopenia
The Physical Fitness Cohort Study in the Community-dwelling Elderly in the WanHwa Area.
The aims of this study are to establish the cohort of elder population based on parameters of health-related fitness, body compositions, blood biochemistry, blood biomarker, balance, quality of life, and musculoskeletal…
- Trial name
- NCT02779088
- Testing
- exercise and nutrition
- Where
- Taiwan
- Volunteers
- 66 people
- Sponsor
- National Taiwan University Hospital
Idiopathic Infantile Hypercalcemia - Severe Form
Vitamin D Analog in Vitamin D 24-hydroxylase Deficiency
Preclinical evaluation of a vitamin D analog for the treatment of vitamin D 24-hydroxylase using fibroblast from patients with CYP24A1 mutation.
- Trial name
- VaraD-Cell (NCT04987073)
- Testing
- skin biopsy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
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