Clinical trials: Cholecalciferol
Post Menopausal Osteoporosis
MOBILE Study - A Study of Bonviva (Ibandronate) Regimens in Women With Post-Menopausal Osteoporosis
This study will compare the efficacy and safety of different treatment regimens of oral Bonviva tablets in women with post-menopausal osteoporosis. Patients will also receive daily supplementation with vitamin D and calcium.
- Trial name
- NCT00048061
- Testing
- Ibandronate [Bonviva/Boniva], Calcium, Vitamin D
- Where
- 68 sites in United States, Australia and 17 more
- Volunteers
- 1,609 people
- Sponsor
- Hoffmann-La Roche
Charcot-Marie-Tooth Disease
Irisin Levels in Patients With Charcot-Marie-Tooth (CMT) Disease
Irisin is an exercise-mimetic myokine secreted by skeletal muscle. Compelling evidence in animal models and humans showed that Irisin prevents onset of musculoskeletal atrophy and its low serum levels are predictive of…
- Trial name
- IRICDE (NCT04786522)
- Testing
- Bioimpedenziometry, Handgrip strenght evaluation, Evaluation on blood specimens
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Bari
Nursing Home, Vitamin D Deficiency
SUN LIGHT EXPOSURE AND VITAMIN D LEVEL IN NURSING HOME
Objective: The aim of the present study was to determine the effect of nursing interventions and sunlight exposure to reach optimum vitamin D levels by individuals living in nursing homes on vitamin D levels.
- Trial name
- NCT04469257
- Testing
- Sunbathing
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Tokat Gaziosmanpasa University
Healthy Participants
Influenza Virus Vaccine Plus Vitamin A and D Supplements for Prevention of Respiratory Virus Infections in Children
Children are particularly vulnerable to respiratory virus infections, especially influenza. Vitamin A \& D deficiencies are associated with vulnerability to infectious diseases of the respiratory tract.
- Trial name
- NCT02649192
- Testing
- Influenza virus vaccine, Vitamins A and D
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Osteoporosis
4-Week Study to Assess the Effect of Alendronate and Vitamin D3 Once Weekly on Fractional Calcium Absorption in Postmenopausal Osteoporotic Women (0217A-230)
To compare change in fractional calcium absorption following administration of MK0217A relative to matching placebo, in postmenopausal women with osteoporosis
- Trial name
- NCT00641771
- Testing
- alendronate sodium (+) cholecalciferol
- Volunteers
- 56 people
- Sponsor
- Organon and Co
Benign Breast Disease
VITamin D and OmegA-3 TriaL: Effects on Mammographic Density and Breast Tissue
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is an ongoing randomized clinical trial in 25,875 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids…
- Trial name
- VITAL (NCT02239874)
- Testing
- Vitamin D and fish oil
- Where
- United States
- Volunteers
- 3,894 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Chronic Sinusitis
Vitamin D for Chronic Sinusitis
The purpose of this study is to examine if vitamin D improves the symptoms of chronic sinusitis.
- Trial name
- NCT01007799
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago
Falling Injury, Nutrition Disorder
Malnutrition's Role in Fall Risk
Falls and falls related injuries are considered one of the most adverse events that a patient can experience. Several assessment instruments to assess and mitigate risks for falls have been developed.
- Trial name
- NCT03011918
- Testing
- Data Collection prior to first fall for all fallers, Hgb value, Vitamin D
- Where
- United States
- Volunteers
- 485 people
- Sponsor
- Louis Stokes VA Medical Center
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Vitamin A and D Supplementation in Allogeneic HCT
The therapy under investigation is the addition of 300 000 IU of vitamin A and 100 000 IU of vitamin D before conditioning. The study will include patients with malignant diseases in hematologic response with indications for…
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Biphenotypic Acute Leukemia, Lymphoblastic Lymphoma
- Trial name
- VitaStem (NCT06508099)
- Testing
- Vitamin A, Vitamin D3
- Where
- Russia
- Volunteers
- 220 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Cystic Fibrosis
Clearance of 25-hydroxyvitamin D in Cystic Fibrosis
The goal of this study is to define 25(OH)D3 catabolism in CF patients using gold standard pharmacokinetics studies. Specifically, the investigators will evaluate the metabolic clearance of 25(OH)D3 among participants with CF and…
- Trial name
- CF (NCT03104855)
- Testing
- d6-25-hydroxyvitamin D3
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Washington
Fractures, Bone
A Study to Compare Denosumab With Zoledronic Acid in Subjects With Bone Metastases From Solid Tumors
This is a randomized, double-blind, double-dummy study designed to provide bridging data in an Asian population to Amgen's studies of denosumab in subjects with bone metastases from solid tumors.
- Trial name
- NCT01920568
- Testing
- Denosumab 70 mg/mL, Zoledronic acid 4 mg, Calcium supplement
- Where
- 25 sites in China, Singapore and 1 more
- Volunteers
- 487 people
- Sponsor
- GlaxoSmithKline
Determine Effect of Vitamin D on Bone Health in Elderly African American Women
Vitamin D and Osteoporosis Prevention in Elderly African American Women
Vitamin D is a hormone that is produced when sunlight is absorbed by the skin. Vitamin D insufficiency has been recognized as a problem in areas where sun exposure is limited, especially in the wintertime.
- Trial name
- NIHD (NCT01153568)
- Testing
- Vitamin D 3
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Supplemental Vitamin D on Skeletal Muscle Function in Chronic Obstructive Pulmonary Disease (COPD) Patients
The purpose of this study is to determine whether or not vitamin D supplementation can improve physical performance in persons with severe chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00914810
- Testing
- Vitamin D (cholecalciferol)
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Cancer, Neuropathy
Vit D3 and Omega 3 in Chemo Induced Neuropathy
The purpose of this study is to determine whether administration of mammalian Omega 3 FA(fatty acid) with Vitamin D3 supplements would lower or prevent the risk of neuropathy due to chemotherapy.
- Trial name
- NCT02294149
- Testing
- mammalian Omega 3 Fatty acids
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Osteoporosis, Osteopenia
Adding Phosphorus to Osteoporosis Drug Treatment
Osteoporosis causes bones to weaken and break more easily. Calcium and phosphorus are two minerals that are essential for normal bone formation.
- Trial name
- NCT00074711
- Testing
- Calcium carbonate, Calcium Phosphate
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Creighton University
Bone Diseases, Breast Neoplasms
Women's Health Initiative (WHI)
To address cardiovascular disease, cancer, and osteoporosis, the most common causes of death, disability, and impaired quality of life in postmenopausal women.
- Conditions
- Bone Diseases, Breast Neoplasms, Cardiovascular Diseases, Colonic Neoplasms
- Trial name
- NCT00000611
- Testing
- hormone replacement therapy, estrogens, progestins
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Multiple Sclerosis
Sunlight-mediated Inter-organ Leukocyte Exchange
Ultraviolet B (UVB) irradiation induces regulatory immune cell types that may transmigrate from the skin to the blood and to the central nervous system and exert regulatory effects.
- Trial name
- SMILE (NCT05627609)
- Testing
- 311 nm narrowband UVB irradiation
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Chronic Kidney Disease, Secondary Hyperparathyroidism
Active Vitamin D Effect on Left Ventricular Hypertrophy
Left ventricular hypertrophy (LVH) predicts mortality at start of dialysis. Prevention of of LVH is important. It is not known whether secondary hyperparathyroidism might induce LVH.
- Conditions
- Chronic Kidney Disease, Secondary Hyperparathyroidism, Left Ventricular Hypertrophy
- Trial name
- NCT00175149
- Testing
- Alfacalcidiol
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Per Ivarsen
Chronic Kidney Disease, Secondary Hyperparathyroidism
Safety/Efficacy Study of CTAP101 in Chronic Kidney Disease Subjects With Secondary Hyperparathyroidism (SHPT)
This study will investigate how the levels of a repeat dose of CTAP101 changes in the body over time (pharmacokinetics, PK) and how CTAP101 affects other mineral and hormonal balances (pharmacodynamics, PD) in patients with…
- Conditions
- Chronic Kidney Disease, Secondary Hyperparathyroidism, Vitamin D Insufficiency
- Trial name
- NCT01219855
- Testing
- Cohort 1 CTAP101 Capsules- 60µg, Cohort 1 CTAP101 Capsules - 90µg, Cohort 1 Matching Sugar Capsule
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- OPKO Health, Inc.
Hyperglycemia, Postprandial, Vitamin D Status
Diabetes Risk in London and Its Association with Vitamin D by Ethnic Group (DELVE)
The goal of this study is to investigate the relationship between vitamin D status and a diabetes risk factor, postprandial glycaemic response in White, South Asian and Black African Caribbean populations in London.
- Trial name
- DELVE (NCT06241976)
- Testing
- Glucose drink, Pure orange juice
- Where
- United Kingdom
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- City, University of London
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