Clinical trials: Clarithromycin, completed
Preterm Premature Rupture of the Membranes
Antibiotics Study in Preterm Premature Rupture of the Membranes
The purpose of this study is to compare the efficacy on maternal infection, chorioamnionitis and neonatal morbidity and mortality, and to review the evidence and provide recommendations on the use of antibiotics in PPROM.
- Trial name
- PPROM (NCT01401179)
- Testing
- cefazolin, erythromycin, clarithromycin
- Where
- South Korea
- Volunteers
- 101 people
- Sponsor
- Samsung Medical Center
Narcolepsy Without Cataplexy, Idiopathic Hypersomnia
Clarithromycin Mechanisms in Hypersomnia Syndromes
The purpose of this study is to evaluate a medication called clarithromycin for treating sleepiness in narcolepsy and idiopathic hypersomnia.
- Conditions
- Narcolepsy Without Cataplexy, Idiopathic Hypersomnia, Narcolepsy With Cataplexy
- Trial name
- NCT04026958
- Testing
- Clarithromycin
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Emory University
Helicobacter Infection
Efficacy of High Dose Dual Therapy, Sequential Therapy and Triple Therapy in H. Pylori Eradication
Up to now, to our knowledge, there is few randomized, large scale study prospectively and simultaneously comparing the efficacy, adverse effects and patient adherence of these current recommended 1st-line or 2nd-line regimens for…
- Trial name
- NCT01163435
- Testing
- high dose dual therapy, sequential therapy, clarithromycin-based triple therapy
- Where
- Taiwan
- Volunteers
- 618 people
- Sponsor
- National Taiwan University Hospital
Healthy Volunteers
Assessment of Change in CYP3A Activity by Route of Administration Using Metabolic Markers in Healthy Male Volunteers
The study objective is to evaluate and validate of endogenous markers for the assessment of change in CYP3A activity by route of administration in Korean healthy subjects using metabolomics.
- Trial name
- CYP_IVPO (NCT03366974)
- Testing
- Midazolam, Clarithromycin, Grapefruit juice
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
CLARITHROMYCIN/DILTIAZEM [VA Drug Interaction]
Study to Evaluate the Interaction Potential of Clarithromycin XL on Diltiazem Hydrochloride Cream 2% in Healthy Subjects
The purpose of this study is to evaluate the drug-drug interaction potential of clarithromycin XL on Diltiazem hydrochloride (DTZ) 2% cream.
- Trial name
- NCT02080780
- Testing
- Clarithromycin XL, 2% Diltiazem
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ventrus Biosciences, Inc
Mycobacterium Avium-intracellulare Infection, HIV Infections
Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDS
To compare the safety and efficacy of two doses of clarithromycin in combination with ethambutol and either rifabutin or clofazimine for the treatment of disseminated Mycobacterium avium Complex (MAC) disease in AIDS patients.
- Trial name
- NCT00001047
- Testing
- Ethambutol hydrochloride, Clarithromycin, Clofazimine
- Where
- 16 sites in United States
- Volunteers
- 400 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Helicobacter Pylori Infection, Obesity, Morbid
THE EFFECT OF HELICOBACTER PYLORI ERADICATION THERAPY TO GASTRIC WALL THICKNESS BEFORE THE LAPAROSCOPIC SLEEVE GASTRECTOMY
Laparoscopic sleeve gastrectomy is one of the most popular bariatric surgery in the world. The most important complication about this surgery that the leakage from the stapler line because of the inconvenient stapler choice..The…
- Trial name
- NCT03757650
- Testing
- Bismuth Subsalicylate
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Helicobacter Pylori Infection
Comparing the Efficacy of Hybrid, High-dose Dual and Bismuth Quadruple Therapies
Both hybrid and high-dose dual therapies developed by the scholars from Taiwan can achieve a high eradication rate for clarithromycin-resistant strains, and have a great potential to replace bismuth quadruple therapy in the…
- Trial name
- NCT03779074
- Testing
- 10d bismuth quadruple therapy, 14d hybrid therapy, 14D high-dose dual therapy
- Where
- Taiwan
- Volunteers
- 918 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Nontuberculous Mycobacteria, Mycobacterium Avium Complex
Clarithromycin for the Treatment of Infections Caused by Nontuberculous Mycobacteria (NTM)
Use of oral clarithromycin for treatment of chronic lung disease due to Mycobacterium avium-intracellulare and other non-tuberculous Mycobacteria
- Trial name
- NCT00600769
- Testing
- Clarithromycin
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- The University of Texas Health Science Center at Tyler
Vitamin D and Calcium Homeostasis
CYP3A4 Activity and Mineral Homeostasis
The purpose of this study is to determine whether changes in the activity of the enzyme CYP3A4 can change the Vitamin D and bone mineral homeostasis.
- Trial name
- NCT02019875
- Testing
- Rifampin, Clarithromycin, Grapefruit Juice
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Washington
Chronic Lung Disease
Efficacy of Clarithromycin Treatment in Prevention of Chronic Lung Disease in Premature Infants
The purpose of this study is to evaluate the efficacy of clarithromycin in eradication of ureaplasma urealyticum and prevention of chronic lung disease in premature infants with birthweight < 1250 g and have ureaplasma…
- Trial name
- NCT01326611
- Testing
- Clarithromycin, Dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 273 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Peptic Ulcer, Dyspepsia
Aizthromycin or Clarithromycin in H-pylori Eradication Regimen
The Aim of this study is comparison between two regimens containing clarithromycinand azithromycin.
- Conditions
- Peptic Ulcer, Dyspepsia, H-pylori
- Trial name
- H-pylori (NCT01667692)
- Testing
- azithromycin, clarithmycin
- Where
- Iran
- Volunteers
- 78 people
- Sponsor
- Shahid Sadoughi University of Medical Sciences and Health Services
Healthy
Evaluation of Metabolic Markers for the Prediction of DDI of Various CYP3A Substrates and Inhibitors
Evaluation and validation of metabolic markers for the prediction of drug-drug interaction of various CYP3A4 substrates (sildenafil) and inhibitors (erythromycin/itraconazole) in healthy male subjects
- Trial name
- NCT02975037
- Testing
- Sildenafil, Clarithromycin, Itraconazole
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
H. Pylori Infection
H. Pylori Treatment Between Modified Quadruple Regimen and Tailored Therapy
The rate of H. pylori resistance to antimicrobial agents including clarithromycin (CAM) has increased worldwide. Eradication failure using triple therapy is strongly associated with CAM-resistant H. pylori.
- Trial name
- NCT05002595
- Testing
- H. pylori eradication
- Where
- South Korea
- Volunteers
- 270 people
- Sponsor
- Soonchunhyang University Hospital
Helicobacter Pylori Infection
15-day Sequential Therapy for Helicobacter Pylori Infection in Korea
10-day sequential therapy was not sufficient to overcome tough situation for H. pylori eradication in Korea due to high antimicrobial resistance.
- Trial name
- NCT01887249
- Testing
- Clarithromycin, metronidazole, esomeprazole
- Where
- South Korea
- Volunteers
- 287 people
- Sponsor
- Seoul National University Bundang Hospital
Mycobacterium Avium-intracellulare Infection, HIV Infections
The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected Patients
PER 03/10/94 AMENDMENT: PART B. To determine whether there is an effect on plasma drug levels of azithromycin and rifabutin as measured by changes in the plasma concentration-time curve (AUC) when these drugs are taken…
- Trial name
- NCT00001023
- Testing
- Clarithromycin, Azithromycin, Rifabutin
- Where
- 11 sites in United States
- Volunteers
- 91 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HELICOBACTER PYLORI INFECTIONS
Efficacy and Safety of 14-Day Vonoprazan-Based Dual Therapy Versus Quadruple Therapy for Helicobacter Pylori Eradication: A Multicentre, Non-Inferiority Randomized Controlled Trial
This study is a multicentre, non-inferiority randomized controlled trial to compare the efficacy and safety of 14-day vonoprazan-based dual therapy with versus quadruple therapy for the eradication of Helicobacter pylori.
- Trial name
- NCT07179159
- Testing
- 14-day vonoprazan-amoxicillin dual therapy, 14-day vonoprazan-amoxicillin-levofloxacin-bismuth quadruple therapy, 14-day vonoprazan-amoxicillin-clarithromycin-bismuth quadruple therapy
- Where
- 2 sites in China
- Volunteers
- 372 people
- Sponsor
- Yanqing Li
Otitis Media, Tonsillitis
Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infections
This study was performed in children with upper respiratory tract infections (acute ear infection, infection of the tonsils or throat, or bacterial inflammation of the bronchi) who needed treatment with an antibiotic…
- Conditions
- Otitis Media, Tonsillitis, Pharyngitis, Bronchitis
- Trial name
- DoSe iT (NCT04016051)
- Testing
- Clarithromycin DST (125 mg), Clarithromycin DST (187.5 mg), Clarithromycin DST (250 mg)
- Where
- 20 sites in Germany, Poland
- Volunteers
- 265 people
- Sponsor
- Grünenthal GmbH
Dyspepsia, Helicobacter-associated Gastritis
High Dose PPI Triple Therapy Versus Sequential Therapy for Helicobacter Pylori Eradication
The purpose of this study is to compare the efficacy between 1-day high dose PPI-based triple therapy vs. 10-day sequential therapy for Helicobacter pylori eradication in functional dyspepsia patients.
- Conditions
- Dyspepsia, Helicobacter-associated Gastritis, Stomach Disorders
- Trial name
- NCT01888237
- Testing
- Double dose of PPI, sequence of drug use
- Where
- Thailand
- Volunteers
- 118 people
- Sponsor
- Mahidol University
Atypical; Mycobacterium, Pulmonary, Tuberculous
Treatment of Mycobacterium Xenopi Pulmonary Infection
The purpose of this study is to determine the 6-months sputum conversion rate with a clarithromycin or moxifloxacin containing regimen in patients with a M. xenopi pulmonary infection.
- Trial name
- CAMOMY (NCT01298336)
- Testing
- Clarithromycin, Moxifloxacin
- Where
- 52 sites in France
- Volunteers
- 92 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens