Clinical trials: Clarithromycin, completed
Lymphoma
Salvage Therapy With High Dose Oral Clarithromycin in Relapsed or Refractory Extranodal Marginal Zone Lymphoma
This is a prospective, phase II study on the activity and tolerability of high dose (2 g/day) oral clarithromycin for the treatment of relapsed or refractory extranodal marginal zone lymphoma.
- Trial name
- HD-K (NCT01516606)
- Testing
- clarithromycin, oral, high dose
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Andres J. M. Ferreri
Gastric Cancer, Helicobacter Pylori Infection
Helicobacter Pylori Eradication With Different Bismuth Quadruple Therapies
This study aims to compare efficacy and safety of bismuth-containing quadruple therapy（with rabeprazole amoxicillin clarithromycin）of different kinds of bismuth（Bismuth potassium citrate, pectin bismuth capsules, pectin bismuth…
- Conditions
- Gastric Cancer, Helicobacter Pylori Infection, Bismuth
- Trial name
- NCT04209933
- Testing
- Bismuth potassium citrate containing quadruple therapy, Colloidal pectin bismuth capsules containing quadruple therapy, Colloidal pectin bismuth particles A quadruple therapy
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Healthy
Drug-Drug Interaction Study Between CJ-12420 and Clarithromycin in Healthy Male Subjects
Primary Objective: To assess the effect of the coadministration of multiple dose of CJ-12420 and clarithromycin on the pharmacokinetics (PK) of CJ-12420 or clarithromycin.
- Trial name
- NCT02052336
- Testing
- CJ-12420 200mg + Clarithromycin 500mg, CJ-12420 200mg, Clarithromycin 500mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation
Mycobacterium Avium-intracellulare Infection, HIV Infections
The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected Patients
To compare the efficacy and safety of clarithromycin alone versus rifabutin alone versus the two drugs in combination for the prevention or delay of Mycobacterium avium Complex (MAC) bacteremia or disseminated MAC disease.
- Trial name
- NCT00001030
- Testing
- Clarithromycin, Rifabutin
- Where
- 42 sites in United States, Tanzania
- Volunteers
- 1,100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Gastrointestinal Ulcer Haemorrhage, Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
Helicobacter Eradication Aspirin Trial
HEAT (Helicobacter Eradication Aspirin Trial) is a large simple double-blind placebo controlled outcomes study of Helicobacter pylori (H. pylori) eradication to prevent ulcer bleeding in aspirin users.
- Trial name
- HEAT (NCT01506986)
- Testing
- Lansoprazole 30mg, Clarithromycin 500mg, Metronidazole 400mg
- Where
- 6 sites in United Kingdom
- Volunteers
- 30,024 people
- Sponsor
- University of Nottingham
Venous Thromboembolism
Effect of Clarithromycin on the Pharmacokinetics of Apixaban in Healthy Participants
This study is to evaluate the effects of multiple-dose clarithromycin on the single-dose pharmacokinetics (PK) of apixaban with parameters like Cmax, AUC(INF), and AUC(0-T).
- Trial name
- NCT02912234
- Testing
- Apixaban, Clarithromycin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Myeloma
Ixazomib With Pomalidomide, Clarithromycin and Dexamethasone in Treating Patients With Multiple Myeloma
This phase I/II trial studies the side effects and best dose of clarithromycin when given together with ixazomib citrate, pomalidomide, and dexamethasone and to see how well it works in treating patients with multiple myeloma…
- Trial name
- NCT02542657
- Testing
- Clarithromycin, Dexamethasone, Ixazomib Citrate
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Joseph Tuscano
Hypersomnia, Idiopathic Hypersomnia
Clarithromycin for the Treatment of Hypersomnia
The term 'hypersomnia' describes a group of symptoms that includes severe daytime sleepiness and sleeping long periods of time (more than 10 hours per night).
- Conditions
- Hypersomnia, Idiopathic Hypersomnia, Narcolepsy
- Trial name
- NCT01146600
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Lynn Marie Trotti
Peptic Ulcer Hemorrhage
Ilaprazole for the Treatment and Prevention of Peptic Ulcer Bleeding in Chinese Patients
The purpose of this phase study is to confirm the efficacy and safety by compare ilaprazole and omeprazole in the treatment and prevention of peptic ulcer bleeding.
- Trial name
- NCT03362281
- Testing
- Ilaprazole, Omeprazole, Ilaprazole tablet
- Volunteers
- 540 people
- Sponsor
- Livzon Pharmaceutical Group Inc.
Neoplasm, Neoplasm Metastasis
A Study of LY2835219 in Participants With Cancer
The purpose of this study is to assess how the body handles Abemaciclib when it is given with another drug called clarithromycin.
- Trial name
- NCT02117648
- Testing
- Abemaciclib, Clarithromycin
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Eli Lilly and Company
Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
Rifaximin Associated With Classic Triple Therapy for the Eradication of Helicobacter Pylori Infection
Background: A progressive decrease in Helicobacter pylori eradication rates has been described over the years, so new combinations of antibiotics for treatment are needed.
- Trial name
- R+OCA (NCT03124199)
- Testing
- Rifaximin
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Helicobacter Pylori Infection
Comparing the Efficacy of Reverse Hybrid Therapy and Concomitant Therapy
Reverse hybrid therapy achieves a higher eradication rate than concomitant therapy remains unanswered.
- Trial name
- NCT02646332
- Testing
- (dexlan+amox+clar+metr)+(dexlan+amox), dexlan+clarith+amox+metro
- Where
- Taiwan
- Volunteers
- 248 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Oxidative Stress
Study of the Ability of Clarithromycin to Induce Oxidative Stress
The purpose of the study is to examine whether Klacid® (Clarithromycin) will induce oxidative stress (stress from oxygen) in healthy subjects.
- Trial name
- CLAROX (NCT00707330)
- Testing
- Clarithromycin
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
COVID-19, Virus Diseases
Anti-inflammatory Clarithromycin for Improving COVID-19 Infection Early
Recent information appearing from different countries suggest that treatment of Coronavirus disease 2019 (COVID-19) with hydroxychloroquine or with a combination of hydroxychloroquine and azithromycin has either an indifferent…
- Conditions
- COVID-19, Virus Diseases, Corona Virus Infection
- Trial name
- ACHIEVE (NCT04398004)
- Testing
- Clarithromycin
- Where
- 9 sites in Greece
- Volunteers
- 90 people
- Sponsor
- Hellenic Institute for the Study of Sepsis
Helicobacter Pylori Infection
Triple Therapy With Tegoprazan in H. Pylori Positive Patients_PILOT
This study aims to compare safety and efficacy in an exploratory manner between a Tegoprazan triple therapy and a RAPAE01 triple therapy in H. pylori positive patients.
- Trial name
- NCT04128917
- Testing
- Tegoprazan, RAPAE01
- Where
- South Korea
- Volunteers
- 102 people
- Sponsor
- HK inno.N Corporation
Gastric Cancer, Helicobacter Pylori Infection
A Real World Study of Bismuth Colloidal Pectin Granules Quadruple Therapy for H. Pylori Eradication
To observe the eradication rate of H. pylori infection, symptom improvement and the incidence of adverse effects in patients using a bismuth colloidal pectin granules quadruple therapy.
- Conditions
- Gastric Cancer, Helicobacter Pylori Infection, Bismuth
- Trial name
- NCT04660123
- Testing
- Bismuth Colloidal Pectin Granules Quadruple Therapy for H. Pylori Eradication
- Where
- China
- Volunteers
- 959 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Healthy
A Drug Interaction Study of Clarithromycin and LY3502970 in Healthy Participants
The main purpose of this study is to determine the levels of study drug called LY3502970 in the blood stream when administered alone and in combination with clarithromycin in healthy participants.
- Trial name
- NCT05469126
- Testing
- LY3502970, Clarithromycin
- Where
- Singapore
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Respiratory Tract Infections
Evaluation of the Treatment With Klacid SR in Patients With Acute Tracheitis, Tracheobronchitis and Bronchitis, Acute Exacerbation of Chronic Bronchitis and Mild Community-acquired Pneumonia in Common Clinical Practice in Ukraine
To describe the relief of symptoms, tolerability, and compliance of treatment with Klacid® sustained release (SR) at a dose of 1000 mg once daily in patients with acute tracheitis, acute tracheobronchitis, acute bronchitis, or in…
- Trial name
- KLARAINE (NCT01095978)
- Testing
- Clarithromycin (Klacid SR)
- Where
- 126 sites in Ukraine
- Volunteers
- 2,822 people
- Sponsor
- Abbott
Helicobacter Pylori Infection
Recurrence Rate Comparison Between Esomeprazole and Lansoprazole in Eradicating Helicobacter Pylori Infection Among Children
This study aims to compare the recurrence rates of Esomeprazole and Lansoprazole in triple combination therapy to eradicate H.pylori infection in children.
- Trial name
- NCT05861687
- Testing
- Esomeprazole, Lansoprazole, Amoxicillin
- Where
- 2 sites in Indonesia
- Volunteers
- 51 people
- Sponsor
- Finni Kollins
Helicobacter Infected Patients
Comparison of Conventional Triple Therapy Versus Sequential Therapy for H. Pylori in Peptic Ulcer Disease: Prospective Randomized Trial
The purpose of this study is to improve first line Helicobacter pylori eradication rate and to compare the sequential versus conventional triple therapy.
- Trial name
- NCT01418300
- Testing
- sequential versus triple
- Where
- South Korea
- Volunteers
- 159 people
- Sponsor
- Jun-Won Chung