Clinical trials: Clarithromycin, completed
Healthy
Comparative Bioavailability Study of Clarithromycin 250 mg Tablets
The objective of this study was to investigate the bioequivalence of Genpharm's clarithromycin tablets following a single, oral 250 mg (1 x 250 mg) dose compared to the Biaxin® filmtab® (Abbott Laboratories USA) administered…
- Trial name
- NCT00648830
- Testing
- Clarithromycin
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mylan Pharmaceuticals Inc
Drug Interactions
Influence of OATP1B1 and CYP2C9 Genotypes on the Pharmacokinetics of Bosentan Before and During Clarithromycin
The aim of the present study is to assess the impact of the OATP1B1 genotype (SLCO1B1*15 vs. wild type; ~2% SLCO1B1*15 haplotypes in Caucasian population) and the CYP2C9 genotype (*2 and *3 allele vs.
- Trial name
- NCT01425229
- Testing
- Bosentan
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gerd Mikus
Helicobacter Pylori Infection
The Efficacy of Susceptibility Test -Driven Sequential Therapy as the Third Line Therapy for Refractory Helicobacter Pylori Infection
Background: Helicobacter pylori infection has been shown to be associated with the development of gastric cancer and peptic ulcer diseases. Eradication of H.
- Trial name
- NCT01032655
- Testing
- susceptibility test guided sequential therapy
- Where
- Taiwan
- Volunteers
- 134 people
- Sponsor
- National Taiwan University Hospital
Helicobacter Infection
Comparison of Daily Single Dose Triple and Conventional Triple Therapies for Helicobacter Pylori Infection
This study is conducted to investigate whether the efficacy of single-dose triple therapy (Esomeprazole 40 mg, Tinidazole 1 g, and Levofluxacine 500 mg) for 14 days is superior to double-dose lansoprazole 30 mg, amoxicillin 1 g…
- Trial name
- NCT02711176
- Testing
- Nexium, Tinafas, Tavanex
- Where
- Iran
- Volunteers
- 212 people
- Sponsor
- Zahra Vahdat Shariatpanahi
Helicobacter Pylori Infection
High Dose Dual Therapy vs Clarithromycin Triple Therapy for Treatment Naive H Pylori Infection in an Urban Population
A phase 4 prospective, randomized, open-label clinical trial evaluating the efficacy of high dose dual therapy vs standard triple therapy in a diverse, urban New York City population.
- Trial name
- NCT05342532
- Testing
- Amoxicillin, Omeprazole, Clarithromycin
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
H. Pylori Infection
A Comparative Study Between Concomitant Versus Load Therapy in Eradication of Helicobacter Pylori Infection
All patients who presented with epigastric pain and dyspeptic symptoms will undergo endoscopic gastric biopsies. The patients will be subjected to: Full history taking, clinical examination, liver function tests, renal function…
- Trial name
- NCT06050824
- Testing
- Comparing Load and Concomitant therapy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Helwan University
Helicobacter Pylori Infection, Dyspepsia
Assessment and Management of Chronic Dyspepsia in Eastern Uganda
Chronic dyspepsia, or a sensation of indigestion, remains an underdiagnosed and often inappropriately managed cause of morbidity in countries with limited medical resources.
- Trial name
- NCT04525664
- Testing
- Clarithromycin 500mg, Amoxicillin 1000 MG, Omeprazole 40 MG
- Where
- United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Aggressive Periodontitis, Generalized
Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis
The aim of this project is to compare the efficacy and the local effect of the association of single or repeated application of photodynamic therapy (PDT) with antibiotic agents using Amoxicillin + Metronidazole or Clarithromycin…
- Trial name
- NCT03132714
- Testing
- Full-mouth ultrasonic debridement, Amoxicillin 500mg, Metronidazole 400mg
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Helicobacter Pylori Resistance
Helicobacter Pylori Resistance
The main goal of the study was to characterize the morbidity, immunological, microbiolical and clinical phenotypes of patients with treated- resistance to Helicobacter pylori (HP) infection, and the effect of triple therapy…
- Trial name
- CRIHEP (NCT05019586)
- Testing
- levofloxacin, amoxicillin, clarithromycin
- Volunteers
- 185 people
- Sponsor
- University Hospital of North Norway
Parkinson's Disease
A Drug Interaction Study of KW-6356 and Clarithromycin or Rifampicin
The purpose of this study is to investigate the effects of CYP3A4/5 inhibitor or inducer on the pharmacokinetics of KW-6356 when CYP3A4/5 inhibitor or inducer is orally administered to healthy Japanese men for 7 days.
- Trial name
- NCT04070495
- Testing
- KW-6356, Clarithromycin, Rifampicin
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kyowa Kirin Co., Ltd.
Helicobacter Pylori Infection
Comparison of Hybrid and Bismuth Quadruple Therapies for Helicobacter Pylori Eradication
According the Maastricht IV consensus report publish in the Gut 2012, bismuth containing quadruple therapy was suggested to be the first choice for eradication therapy of Helicobacter pylori in the area with high clarithromycin…
- Trial name
- NCT02541864
- Testing
- Bismuth quadruple therapy, Hybrid therapy
- Volunteers
- 330 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Helicobacter Pylori Infection, Family History of Stomach Cancer
Comparison of 7-day PPI-based Standard Triple Therapy and 10-day Bismuth Quadruple Therapy for H. Pylori Eradication
In this randomized controlled trial, we investigate the effect of 10-day bismuth quadruple therapy in comparison with that of 7-day PPI-based standard triple as 1st line treatment for H. pylori.
- Trial name
- NCT02557932
- Testing
- Standard triple therapy, Bismuth quadruple therapy
- Where
- South Korea
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Hypersomnolence
Sleep/Wake State Assessment with Non-invasive Earbuds
This study is a within subject's assessment of whether a novel wearable technology, NextSense electroencephalography earbuds (EEGBuds), is able to detect differences in onset to sleep from wake versus in-laboratory, gold-standard…
- Trial name
- NCT05066009
- Testing
- NextSense EEG-enabled earbuds, Ellcie Healthy eyeglasses, Drug Holiday
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Emory University
Toxoplasmosis, Cerebral, HIV Infections
Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic Encephalitis
To evaluate the efficacy, safety, and tolerance of atovaquone with either pyrimethamine or sulfadiazine in AIDS patients with toxoplasmic encephalitis.
- Trial name
- NCT00000794
- Testing
- Sulfadiazine, Clarithromycin, Atovaquone
- Where
- 16 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Lymphoma
Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the Stomach
RATIONALE: Antibiotic therapy and antacids are used to treat Helicobacter pylori infection of the stomach. These treatments may also have an effect on gastric MALT lymphoma of the stomach.
- Trial name
- NCT00002682
- Testing
- Amoxicillin, Bismuth Subsalicylate, Clarithromycin
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- M.D. Anderson Cancer Center
Helicobacter Pylori Infection
Tailored Versus Empiric Therapy for Helicobacter Pylori Treatment
With markedly increased antibiotic resistance and unsatisfactory efficacies of common empiric eradication regimens in the mainland of China, tailored therapy may be the best choice to achieve good efficacy.
- Trial name
- NCT02935010
- Testing
- Esomeprazole, Bismuth Potassium Citrate, Amoxicillin
- Where
- 5 sites in China
- Volunteers
- 382 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine