Clinical trials: Clarithromycin
Staphylococcus Aureus, Motility Disorder
S. Aureus Decolonization in HPN Patients.
This trial focusses on identifying the most effective and safe long-term S. aureus carriage decolonization strategy in home parenteral nutrition patients.
- Trial name
- CARRIER (NCT03173053)
- Testing
- Doxycycline, Trimethoprim, Sulfamethoxazole/trimethoprim
- Where
- 4 sites in Denmark, Netherlands
- Volunteers
- 63 people
- Sponsor
- Radboud University Medical Center
Helicobacter Pylori Infection
Effect of Propolis on Patients Infected With H. Pylori
This research aims to contribute to the literature by researching the effect of propolis as an add-on treatment and nutritional education on patients with H pylori and the alleviation of gastrointestinal symptoms.In order to…
- Trial name
- NCT05259007
- Testing
- propolis solved in lactic acid solvent, Amoxicillin-Clarithromycin-Lansoprazole, IV saline 0.9%
- Volunteers
- 96 people
- Sponsor
- Fatma Zehra Arvas
Helicobacter Pylori 23S rRNA Clarithromycin Resistance Mutation, Helicobacter Pylori Infection
Empirical vs Tailored Therapy for H. Pylori Infection
We aimed to compare the efficacy of genotypic resistance-guided tailored therapy vs empirical therapy for eradication of Helicobacter pylori (H. pylori) infection in randomized controlled trials.
- Trial name
- NCT04006340
- Testing
- triple therapy, quadruple therapy, dual-priming oligonucleotide-based multiplex (DPO)-PCR test
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Seoul National University Hospital
Healthy
Bioequivalence Study of Clarithromycin 250 mg/5 mL Powder for Oral Suspension Under Fasting Conditions
To compare the single-dose oral bioavailability of clarithromycin 250-mg/5 mL powder for oral suspension of Ranbaxy Laboratories with that of Abbott Laboratories (Biaxin®) following administration of a 250 mg/5 mL dose in…
- Trial name
- NCT00775255
- Testing
- clarithromycin 250 mg/5 mL powder for oral suspension
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Helicobacter Pylori Infection
Tegoprazan-Amoxicillin Dual Therapy vs. Bismuth Quadruple Therapy for H. Pylori Infection (TATH-1)
Standard eradication therapies using proton pump inhibitors (PPIs) require double doses to achieve sufficient acid suppression, yet failure rates remain high due to antibiotic resistance.
- Trial name
- TATH-1 (NCT05647278)
- Testing
- Tegoprazan 50 mg, tablets, orally, qd, Esomeprazole 20mg BID, Tegoprazan 50 mg, tablets, orally, bid
- Where
- China
- Volunteers
- 370 people
- Sponsor
- Zhang Xiaofeng,MD
Helicobacter Pylori Infection
Clinical Study to Evaluate the Possible Efficacy and Safety of Diosmin and Hesperidin Combined Therapy in Patients With Helicobacter Pylori Infection
This study intends to assess the possible effectiveness and safety of Diosmin and Hesperidin combination in patients with Helicobacter pylori Infection through evaluating its effect on stool antigen test and serum levels of…
- Trial name
- NCT06546111
- Testing
- Daflon
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Sadat City University
Healthy
Investigation Drug-drug Interaction Between Dabigatran and Clarithromycin
Dabigatran (Pradaxa ®) is a new oral anticoagulant. It is used to prevent venous thromboembolism in orthopedic surgery and has recently demonstrated efficacy and safety at least as good as anticoagulants in the prevention of…
- Trial name
- IMAGINE (NCT01385683)
- Testing
- Dabigatran then dabigatran and clarithromycin, Clarithromycin and dabigatran then dabigatran
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Helicobacter Pylori
Optimized-dose Amoxicillin Versus Standard-dose Amoxicillin for Quadruple Therapy in Helicobacter Pylori Eradication
The goal of this prospective randomized clinical trial is to compare the rate of Helicobacter Pylori (HP) eradication after standard or dose-optimized amoxicillin quadritherapy in patients naïve to any anti-HP treatment and with…
- Trial name
- Helicomatri (NCT05635942)
- Testing
- optimized quadruple therapy, standard quadruple therapy
- Where
- Tunisia
- Volunteers
- 88 people
- Sponsor
- Les Laboratoires des Médicaments Stériles
Helicobacter Pylori Infection, Antibiotic Resistant Infection
Optimal Tailored Treatment for H. Pylori Infection
The efficacy of the current standard triple therapy is at an unacceptably low level. Resistance to antibiotics is suspected to be the major cause of the low efficacy of standard triple therapy.
- Trial name
- NCT04462133
- Testing
- Dual-priming oligonucleotide-based multiplex polymerase chain reaction (DPO-PCR)
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Incheon St.Mary's Hospital
Parkinson's Disease, Helicobacter Pylori Infection
Helicobacter Pylori Eradication Study in Parkinson's Disease
It has been hypothesized, based on epidemiological observations, that Helicobacter pylori (HP) infection may play a role in the pathogenesis of Parkinson's Disease (PD).
- Trial name
- NCT02108704
- Testing
- Helicobacter pylori eradication therapy
- Where
- Malaysia
- Volunteers
- 75 people
- Sponsor
- University of Malaya
Helicobacter Infection
The Efficacy of the Tailored Therapy Based on Antimicrobial Susceptibility for 2nd Eradication of H. Pylori
As increasing the antibiotics resistance, the effectiveness of traditional Helicobacter pylori (H. pylori) therapies has been declined coincidently. In this study, the investigators evaluated the efficacy of H.
- Trial name
- NCT02349685
- Testing
- H. pylori culture and antimicrobial susceptibility test, 14 day PBMT group, 14 day MEA group
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Helicobacter Eradication
Bismuth Quadruple Therapy Versus Modified Bismuth Therapy for Helicobacter Pylori
The primary objective of the study is to compare the efficacy of 2 different regimens of treatment of gastric bacteria (H pylori) these are: quadruple bismuth therapy and clarithromycin triple therapy with add-on bismuth, in…
- Trial name
- NCT07810985
- Testing
- Bismuth added on triple therapy, Quadruple therapy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Reham Abdelkader Elkhouly
Asthma
Asthma Clinical Research Network (ACRN) Trial - Macrolides in Asthma (MIA)
Asthma can be caused by a variety of factors, including tobacco smoke, allergens, and respiratory airway infections. Many people use inhaled corticosteroid medications to treat their symptoms.
- Trial name
- MIA (NCT00318708)
- Testing
- clarithromycin, fluticasone propionate
- Where
- 10 sites in United States
- Volunteers
- 92 people
- Sponsor
- Milton S. Hershey Medical Center
Pulmonary Mycobacterium Avium Complex Infection, Bronchiectasis
RHB-204 for the Treatment of Pulmonary Mycobacterium Avium Complex Disease
A 2-part multi-center, Phase 3, randomized, double-blind, placebo-controlled, parallel group study to evaluate the efficacy and safety of RHB-204 in adult subjects with underlying nodular bronchiectasis and documented MAC lung…
- Conditions
- Pulmonary Mycobacterium Avium Complex Infection, Bronchiectasis, Lung Diseases
- Trial name
- CleaR-MAC (NCT04616924)
- Testing
- RHB-204
- Where
- 25 sites in United States
- Volunteers
- 12 people
- Sponsor
- RedHill Biopharma Limited
Helicobacter Pylori Infection
Jinghua Weikang Capsule Containing Quadruple Therapy for IgAN With Helicobacter Pylori Infection
This study is to evaluate the efficacy and safety of the Jinghua Weikang Capsule (a Chinese patent medicine for peptic ulcer and gastritis) containing quadruple therapy (Jinghua Weikang Caplsule plus triple therpy) for…
- Trial name
- NCT05320133
- Testing
- JWC containing quadruple therapy, Bismuth-containing quadruple therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University First Hospital
Helicobacter Pylori Infection
Optimized Bismuth Quadruple Therapy vs Triple Standard Therapy for Helicobacter Pylori Eradication
This study have as primary aim "To compare the H. pylori eradication rate between the quadruple bismuth therapy versus the standard triple therapy recommended by the AUGE Clinical Guidelines for Helicobacter pylori eradication…
- Trial name
- NCT05664685
- Testing
- Optimized bismuth quadruple therapy, Control
- Where
- 2 sites in Chile
- Volunteers
- 127 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Helicobacter Pylori Infection
Susceptibility-Guided Therapy for Helicobacter Pylori Infection Treatment
This multicenter randomized controlled clinical trial was conducted to compare the eradication efficacy and health economic benefits of individualized regimens based on HP drug resistance mutation gene detection (multiple PCR…
- Trial name
- NCT05250050
- Testing
- Esomeprazole, Bismuth potassium citrate, Metronidazole
- Where
- 3 sites in China
- Sponsor
- Shanghai Zhongshan Hospital
Helicobacter Pylori Infection, Chronic Gastritis
Study on The Efficacy and Safety of Vonoprazan-containing Berberine Triple Therapy in Helicobacter Pylori First-Line Eradication
The purpose of this study was to evaluate the efficacy and safety of the triple therapy of berberine hydrochloride, vonorasan and amoxicillin for the primary eradication of Helicobacter pylori.It is hypothesized that berberine…
- Trial name
- NCT06514274
- Testing
- Berberine, Vonoprazan, Amoxicillin
- Where
- China
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Burkitt Lymphoma, Lymphoblastic Lymphoma, Adult
Thiotepa, Cyclophosphamide, Clarithromycin and Cytarabine
This study is an observational study on the efficacy and safety of auto-HSCT in adult patients with Burkitt lymphoma, lymphoblastic lymphoma, and acute lymphoblastic leukemia who received TCCA conditioning regimen.
- Conditions
- Burkitt Lymphoma, Lymphoblastic Lymphoma, Adult, Acute Lymphoblastic Leukemia, Adult
- Trial name
- TCCA (NCT06060782)
- Testing
- Thiotepa, cyclophosphamide, cladribine, and cytarabine conditioning regimen
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Helicobacter Pylori Infection
A Study on Eradication Rate of Triple Therapy According to Treatment Period and CYP2C19 Polymorphisms in H.Pylori Patients
This study compared efficacy and safety of basic triple therapy according to treatment period. This study evaluated Effect of CYP2C19 genetic polymorphisms on the efficacy
- Trial name
- NCT03099876
- Testing
- treatment period
- Where
- 4 sites in South Korea
- Volunteers
- 320 people
- Sponsor
- Il-Yang Pharm. Co., Ltd.