Clinical trials: Clarithromycin
Chronic Lung Disease
Efficacy of Clarithromycin Treatment in Prevention of Chronic Lung Disease in Premature Infants
The purpose of this study is to evaluate the efficacy of clarithromycin in eradication of ureaplasma urealyticum and prevention of chronic lung disease in premature infants with birthweight < 1250 g and have ureaplasma…
- Trial name
- NCT01326611
- Testing
- Clarithromycin, Dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 273 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Peptic Ulcer, Dyspepsia
Aizthromycin or Clarithromycin in H-pylori Eradication Regimen
The Aim of this study is comparison between two regimens containing clarithromycinand azithromycin.
- Conditions
- Peptic Ulcer, Dyspepsia, H-pylori
- Trial name
- H-pylori (NCT01667692)
- Testing
- azithromycin, clarithmycin
- Where
- Iran
- Volunteers
- 78 people
- Sponsor
- Shahid Sadoughi University of Medical Sciences and Health Services
Helicobacter Pylori Infection
Efficacy and Safety of Black Seed Oil With Vonoprazan Based Triple Therapy in Treatment of Helicobacter Pylori
The aim of this study is to: Evaluation of efficacy and safety of adding black seed oil with vonoprazan triple therapy ( vonoprazan ,clarithromycin and amoxicillin ) in eradication of Helicobacter pylori infection and this will…
- Trial name
- NCT05957432
- Testing
- Black Seed Oil Cap/Tab, Vonoprazan, Amoxicillin and Clarithromycin
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Healthy
Evaluation of Metabolic Markers for the Prediction of DDI of Various CYP3A Substrates and Inhibitors
Evaluation and validation of metabolic markers for the prediction of drug-drug interaction of various CYP3A4 substrates (sildenafil) and inhibitors (erythromycin/itraconazole) in healthy male subjects
- Trial name
- NCT02975037
- Testing
- Sildenafil, Clarithromycin, Itraconazole
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Granulomatous Mastitis
Antibiotics vs Corticosteroids in Treatment of Granulomatous Lobular Mastitis
The goal of this clinical trial is to find the most effective and safe medical treatment for Granulomatous Lobular Mastitis (GLM) - a rare, chronic inflammatory breast disease that affects young and middle-aged women, often…
- Trial name
- GRANMAS (NCT07454772)
- Testing
- Steroid, Antibiotic
- Where
- India
- Volunteers
- 72 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
H. Pylori Infection
H. Pylori Treatment Between Modified Quadruple Regimen and Tailored Therapy
The rate of H. pylori resistance to antimicrobial agents including clarithromycin (CAM) has increased worldwide. Eradication failure using triple therapy is strongly associated with CAM-resistant H. pylori.
- Trial name
- NCT05002595
- Testing
- H. pylori eradication
- Where
- South Korea
- Volunteers
- 270 people
- Sponsor
- Soonchunhyang University Hospital
Multiple Myeloma, Infection
Clarithromycin, Sulfamethoxazole/Trimethoprim or Observation in Newly Diagnosed Multiple Myeloma
This study evaluates the effect of prophylactic antibiotics in multiple myeloma. One third of patients will received treatment with clarithromycin, one third of patients will receive treatment with sulfamethoxazole/trimethoprim…
- Trial name
- SUTRICA (NCT02624440)
- Testing
- Standard myeloma treatment, Clarithromycin, Sulfamethoxazole/trimethoprim
- Where
- 8 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- Henrik Gregersen
Helicobacter Pylori Infection
15-day Sequential Therapy for Helicobacter Pylori Infection in Korea
10-day sequential therapy was not sufficient to overcome tough situation for H. pylori eradication in Korea due to high antimicrobial resistance.
- Trial name
- NCT01887249
- Testing
- Clarithromycin, metronidazole, esomeprazole
- Where
- South Korea
- Volunteers
- 287 people
- Sponsor
- Seoul National University Bundang Hospital
Mycobacterium Avium-intracellulare Infection, HIV Infections
The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected Patients
PER 03/10/94 AMENDMENT: PART B. To determine whether there is an effect on plasma drug levels of azithromycin and rifabutin as measured by changes in the plasma concentration-time curve (AUC) when these drugs are taken…
- Trial name
- NCT00001023
- Testing
- Clarithromycin, Azithromycin, Rifabutin
- Where
- 11 sites in United States
- Volunteers
- 91 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HELICOBACTER PYLORI INFECTIONS
Efficacy and Safety of 14-Day Vonoprazan-Based Dual Therapy Versus Quadruple Therapy for Helicobacter Pylori Eradication: A Multicentre, Non-Inferiority Randomized Controlled Trial
This study is a multicentre, non-inferiority randomized controlled trial to compare the efficacy and safety of 14-day vonoprazan-based dual therapy with versus quadruple therapy for the eradication of Helicobacter pylori.
- Trial name
- NCT07179159
- Testing
- 14-day vonoprazan-amoxicillin dual therapy, 14-day vonoprazan-amoxicillin-levofloxacin-bismuth quadruple therapy, 14-day vonoprazan-amoxicillin-clarithromycin-bismuth quadruple therapy
- Where
- 2 sites in China
- Volunteers
- 372 people
- Sponsor
- Yanqing Li
Helicobacter Pylori Infection
Influencing Factors of Helicobacter Pylori Infection and Eradication Failure
Helicobacter pylori (H. pylori) is closely related to the occurrence of gastric cancer and other diseases, the discovery and eradication of H.
- Trial name
- NCT05226819
- Testing
- PPI quadruple therapy
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Otitis Media, Tonsillitis
Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract Infections
This study was performed in children with upper respiratory tract infections (acute ear infection, infection of the tonsils or throat, or bacterial inflammation of the bronchi) who needed treatment with an antibiotic…
- Conditions
- Otitis Media, Tonsillitis, Pharyngitis, Bronchitis
- Trial name
- DoSe iT (NCT04016051)
- Testing
- Clarithromycin DST (125 mg), Clarithromycin DST (187.5 mg), Clarithromycin DST (250 mg)
- Where
- 20 sites in Germany, Poland
- Volunteers
- 265 people
- Sponsor
- Grünenthal GmbH
Helicobacter Pylori Infection
Simplified Dual Regimen Guided by Fecal Clarithromycin Resistance Gene Detection for First-line H. Pylori Eradication
To investigate the efficacy, safety, and compliance of a simplified strategy using vonoprazan plus clarithromycin for first-line treatment in patients with Helicobacter pylori infection, among those infected with strains without…
- Trial name
- NCT07439445
- Testing
- Vonoprazan 20 mg twice daily + clarithromycin 500 mg twice daily for 14 days
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University First Hospital
Dyspepsia, Helicobacter-associated Gastritis
High Dose PPI Triple Therapy Versus Sequential Therapy for Helicobacter Pylori Eradication
The purpose of this study is to compare the efficacy between 1-day high dose PPI-based triple therapy vs. 10-day sequential therapy for Helicobacter pylori eradication in functional dyspepsia patients.
- Conditions
- Dyspepsia, Helicobacter-associated Gastritis, Stomach Disorders
- Trial name
- NCT01888237
- Testing
- Double dose of PPI, sequence of drug use
- Where
- Thailand
- Volunteers
- 118 people
- Sponsor
- Mahidol University
Relapse/Refractory Multiple Myeloma
Clarithromycin,Lenalidomide and Dexamethasone for Relapsed/Refractory Myeloma
This phase II study investigating the efficacy and safety of a combination of biaxin,lenalidomide and dexamethasone in subjects with relapsed/refractory MM.
- Trial name
- NCT02986451
- Testing
- clarithromycin, Lenalidomide, Dexamethasone
- Where
- China
- Sponsor
- Sun Yat-sen University
Atypical; Mycobacterium, Pulmonary, Tuberculous
Treatment of Mycobacterium Xenopi Pulmonary Infection
The purpose of this study is to determine the 6-months sputum conversion rate with a clarithromycin or moxifloxacin containing regimen in patients with a M. xenopi pulmonary infection.
- Trial name
- CAMOMY (NCT01298336)
- Testing
- Clarithromycin, Moxifloxacin
- Where
- 52 sites in France
- Volunteers
- 92 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Lymphoma
Salvage Therapy With High Dose Oral Clarithromycin in Relapsed or Refractory Extranodal Marginal Zone Lymphoma
This is a prospective, phase II study on the activity and tolerability of high dose (2 g/day) oral clarithromycin for the treatment of relapsed or refractory extranodal marginal zone lymphoma.
- Trial name
- HD-K (NCT01516606)
- Testing
- clarithromycin, oral, high dose
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Andres J. M. Ferreri
Pediatric Intensive Care Unit, Pediatric Immuno-hematology Department
Population Pharmacokinetics of Anti-infectives in Critically Ill Children
Concentrations and effects of anti-infectives in critically ill children are unpredictable and the risk of under-exposure may be associated with poor clinical outcomes.
- Trial name
- OPTIMOME (NCT02539407)
- Testing
- Pharmacokinetics
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastric Cancer, Helicobacter Pylori Infection
Helicobacter Pylori Eradication With Different Bismuth Quadruple Therapies
This study aims to compare efficacy and safety of bismuth-containing quadruple therapy（with rabeprazole amoxicillin clarithromycin）of different kinds of bismuth（Bismuth potassium citrate, pectin bismuth capsules, pectin bismuth…
- Conditions
- Gastric Cancer, Helicobacter Pylori Infection, Bismuth
- Trial name
- NCT04209933
- Testing
- Bismuth potassium citrate containing quadruple therapy, Colloidal pectin bismuth capsules containing quadruple therapy, Colloidal pectin bismuth particles A quadruple therapy
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Healthy
Drug-Drug Interaction Study Between CJ-12420 and Clarithromycin in Healthy Male Subjects
Primary Objective: To assess the effect of the coadministration of multiple dose of CJ-12420 and clarithromycin on the pharmacokinetics (PK) of CJ-12420 or clarithromycin.
- Trial name
- NCT02052336
- Testing
- CJ-12420 200mg + Clarithromycin 500mg, CJ-12420 200mg, Clarithromycin 500mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- HK inno.N Corporation