Clinical trials: Clarithromycin
Helicobacter Pylori Infection
Efficacy and Safety of 14-day Concomitant Therapy for Difficult-to-Treat Helicobacter Pylori Infection
The purpose of this study is to evaluate efficacy of a 14-day concomitant therapy for the treatment of Hard-to-treat Helicobacter pylori infection, and whether it is safe while maintaining an ideal eradication rates
- Trial name
- NCT05126121
- Testing
- three kinds of antibiotics including amoxicillin，tetracycline, furazolidone, levofloxacin,clarithromycin,levofloxacin,tinidazole,metronidazol
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xiuli Zuo
Helicobacter Pylori Infection, Dyspepsia
Assessment and Management of Chronic Dyspepsia in Eastern Uganda
Chronic dyspepsia, or a sensation of indigestion, remains an underdiagnosed and often inappropriately managed cause of morbidity in countries with limited medical resources.
- Trial name
- NCT04525664
- Testing
- Clarithromycin 500mg, Amoxicillin 1000 MG, Omeprazole 40 MG
- Where
- United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Parkinson's Disease, Helicobacter Infections
Treating H. Pylori in Parkinson's Patients With Motor Fluctuations
The purpose of this study is to determine whether treatment of H. pylori (an infection of the stomach) improves treatment effectiveness in patients with Parkinson's disease and motor fluctuations.
- Conditions
- Parkinson's Disease, Helicobacter Infections, Motor Fluctuations
- Trial name
- NCT00664209
- Testing
- clartihromycin, amoxicillin, and omeprazole
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of California, Los Angeles
Helicobacter Pylori Infection, Early Gastric Cancer
Effects of H. Pylori Eradication on the Gastric Preneoplastic Lesion and Neoplasm After ESD
This study evaluates whether Helicobacter pylori eradication improves precancerous lesions including glandular atrophy and intestinal metaplasia as well as metachronous cancers or dysplasias after endoscopic mucosal resection for…
- Conditions
- Helicobacter Pylori Infection, Early Gastric Cancer, Endoscopic Resection
- Trial name
- NCT02407119
- Testing
- 7 day H.pylori eradication Omeprazole or Rabeprazole, Clarithromycin, Amoxicillin
- Where
- South Korea
- Volunteers
- 470 people
- Sponsor
- National Cancer Center, Korea
Aggressive Periodontitis, Generalized
Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis
The aim of this project is to compare the efficacy and the local effect of the association of single or repeated application of photodynamic therapy (PDT) with antibiotic agents using Amoxicillin + Metronidazole or Clarithromycin…
- Trial name
- NCT03132714
- Testing
- Full-mouth ultrasonic debridement, Amoxicillin 500mg, Metronidazole 400mg
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Multiple Myeloma
GEM-CLARIDEX: Ld vs BiRd
This phase III study, open-label, randomized study investigating lenalidomide and dexamethasone with and without biaxin in subjects with newly diagnosed, previously untreated MM.
- Trial name
- GEM-CLARIDEX (NCT02575144)
- Testing
- Clarithromycin, Lenalidomide, Dexamethasone
- Where
- 26 sites in Spain
- Volunteers
- 286 people
- Sponsor
- PETHEMA Foundation
Helicobacter Pylori Infection
Randomized Study on Efficacy of Gemifloxacin-based Regimen for Helicobacter Pylori Infection
New generations of fluoroquinolones, like levofloxacin and moxifloxacin, exhibit a broad-spectrum activity against Gram-positive and Gram-negative bacteria, and have been successfully introduced into the treatment of Helicobacter…
- Trial name
- NCT02368470
- Testing
- Gemifloxacin-based triple therapy, Standard triple therapy
- Where
- South Korea
- Volunteers
- 252 people
- Sponsor
- Samsung Medical Center
Helicobacter Pylori Resistance
Helicobacter Pylori Resistance
The main goal of the study was to characterize the morbidity, immunological, microbiolical and clinical phenotypes of patients with treated- resistance to Helicobacter pylori (HP) infection, and the effect of triple therapy…
- Trial name
- CRIHEP (NCT05019586)
- Testing
- levofloxacin, amoxicillin, clarithromycin
- Volunteers
- 185 people
- Sponsor
- University Hospital of North Norway
Parkinson's Disease
A Drug Interaction Study of KW-6356 and Clarithromycin or Rifampicin
The purpose of this study is to investigate the effects of CYP3A4/5 inhibitor or inducer on the pharmacokinetics of KW-6356 when CYP3A4/5 inhibitor or inducer is orally administered to healthy Japanese men for 7 days.
- Trial name
- NCT04070495
- Testing
- KW-6356, Clarithromycin, Rifampicin
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kyowa Kirin Co., Ltd.
Helicobacter Pylori Infection
Comparison of Hybrid and Bismuth Quadruple Therapies for Helicobacter Pylori Eradication
According the Maastricht IV consensus report publish in the Gut 2012, bismuth containing quadruple therapy was suggested to be the first choice for eradication therapy of Helicobacter pylori in the area with high clarithromycin…
- Trial name
- NCT02541864
- Testing
- Bismuth quadruple therapy, Hybrid therapy
- Volunteers
- 330 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Helicobacter Pylori Infection, Family History of Stomach Cancer
Comparison of 7-day PPI-based Standard Triple Therapy and 10-day Bismuth Quadruple Therapy for H. Pylori Eradication
In this randomized controlled trial, we investigate the effect of 10-day bismuth quadruple therapy in comparison with that of 7-day PPI-based standard triple as 1st line treatment for H. pylori.
- Trial name
- NCT02557932
- Testing
- Standard triple therapy, Bismuth quadruple therapy
- Where
- South Korea
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Hypersomnolence
Sleep/Wake State Assessment with Non-invasive Earbuds
This study is a within subject's assessment of whether a novel wearable technology, NextSense electroencephalography earbuds (EEGBuds), is able to detect differences in onset to sleep from wake versus in-laboratory, gold-standard…
- Trial name
- NCT05066009
- Testing
- NextSense EEG-enabled earbuds, Ellcie Healthy eyeglasses, Drug Holiday
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Emory University
Gastritis, Gastric Ulcer
A Multi-center Study for Individual Treatment of Helicobacter Pylori Infection
Since the discovery of Helicobacter pylori (H. pylori), many studies have been carried out with the goal of improving H. pylori eradication and therapies have changed from single-antibiotic treatments to the current…
- Trial name
- NCT02689583
- Testing
- Antibiotic selection based on the antibiotic susceptibility testing, PPI selection based on the CYP2C19 gene polymorphism, Probiotics usage based on the 16SrRNA sequencing
- Volunteers
- 3,000 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Functional Dyspepsia, Helicobacter Pylori Infection
Clinical Study to Evaluate the Efficacy and the Safety of Eradication Therapy for Helicobacter Pylori in Functional Dyspepsia
The role of Helicobacter pylori infection in functional dyspepsia remains controversial. Several randomized controlled trials in western countries have shown no significant advantage over placebo.
- Trial name
- NCT00990405
- Testing
- Lansoprzole+Amoxicillin+Clarithromycin
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Korean College of Helicobacter and Upper Gastrointestinal Research
Bronchopulmonary Dysplasia, Necrotizing Enterocolitis
Treatment of Classic Mid-trimester PPROM by Means of Continuous Amnioinfusion
Objective: Mid-trimester preterm premature rupture of membranes (PPROM), defined as rupture of fetal mem-branes prior to 28 weeks' gestation (WG), complicates approximately 0.4-0.7% of all pregnancies and associated with very…
- Conditions
- Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intracranial Hemorrhages
- Trial name
- AmnionFlush (NCT04696003)
- Testing
- Continuous amnioinfusion with Amnion Flush Solution through the intraamniotic catheter
- Where
- Germany
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Immune Thrombocytopenic Purpura, Helicobacter Pylori
H. Pylori Eradication for Moderate ITP
The purpose of this study is to determine the efficacy of H. pylori eradication for the treatment of chronic or persistent immune thrombocytopenic purpura (ITP) patients with moderate thrombocytopenia.
- Conditions
- Immune Thrombocytopenic Purpura, Helicobacter Pylori, Immune Thrombocytopenia
- Trial name
- NCT03177629
- Testing
- treatment : H. pylori eradication
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Seoul National University Hospital
Toxoplasmosis, Cerebral, HIV Infections
Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic Encephalitis
To evaluate the efficacy, safety, and tolerance of atovaquone with either pyrimethamine or sulfadiazine in AIDS patients with toxoplasmic encephalitis.
- Trial name
- NCT00000794
- Testing
- Sulfadiazine, Clarithromycin, Atovaquone
- Where
- 16 sites in United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Lymphoma, Lymphoma, Non-Hodgkin
Helicobacter - Lymphoma - Radiation Part I: Eradication, Part II: Radiation
The first objective of this study is to confirm the results of complete remission of low-grade gastric MALT lymphoma stage IE \& II1E after H. pylori eradication on a larger number of patients (HELYX Part I).
- Trial name
- NCT00154440
- Testing
- proton pump inhibitor, clarithromycin, amoxicillin
- Where
- 3 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Technische Universität Dresden
Lymphoma
Antibiotic Therapy and Antacids in Patients With Malt Lymphoma of the Stomach
RATIONALE: Antibiotic therapy and antacids are used to treat Helicobacter pylori infection of the stomach. These treatments may also have an effect on gastric MALT lymphoma of the stomach.
- Trial name
- NCT00002682
- Testing
- Amoxicillin, Bismuth Subsalicylate, Clarithromycin
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- M.D. Anderson Cancer Center
Pregnancy Complications, Anemia, Iron Deficiency
Eradication of H-pylori in Pregnancy and Its Effect on Iron Replacement Therapy?
the effect of eradication of H-pylori in pregnant patients with iron deficiency anemia on the level of hemoglobin after iron therapy.
- Conditions
- Pregnancy Complications, Anemia, Iron Deficiency, H Pylori Infection
- Trial name
- NCT03347513
- Testing
- triple attack therapy, Ferrous(II)-glycine-sulphate complex 567.7 mg capsules
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital