Clinical trials: Clarithromycin
Helicobacter Pylori Infection
Comparison of Dexlansoprazole-based Triple and Rabeprazole-based Triple Therapies for Helicobacter Pylori Infection
Dexlansoprazole MR is the R-enantiomer of lansoprazole that is delivered by a dual delayed release formulation. It is effective for symptom control of patients with gastroesophageal reflux disease.
- Trial name
- NCT02541786
- Testing
- dexlansoprazole based triple therapy, rabeprazole-based triple therapy
- Where
- 2 sites in Taiwan
- Volunteers
- 177 people
- Sponsor
- Kaohsiung Medical University
Gastritis
A Multi-center Study for Eradication of Helicobacter Pylori With Triple Therapy Using Clarithromycin
As the resistant rate of the Helicobacter pylori to some common antibiotics was rising，the eradication rate of the Helicobacter pylori with the standard triple therapy failed to exceed 70% in China，and had to drop out of the…
- Trial name
- NCT02923856
- Testing
- The results of clarithromycin susceptibility test of H. pylori isolates, Computer generated random number, randomly assigned into groups, The result of 13C-urea breath test of patient in 7days/10days/14days treatment groups
- Where
- China
- Volunteers
- 672 people
- Sponsor
- Sanmen People's Hospital
Helicobacter Pylori Infection
Bismuth-containing Quadruple Therapy for Helicobacter Pylori Eradication
The researchers collect treatment-naive H.pylori-positive patients from the outpatient clinic. The subjects were randomized to receive a 10-day or 14-day course of quadruple eradication therapy.
- Trial name
- NCT05049902
- Testing
- Amoxicillin, Clarithromycin, Tetracycline
- Where
- 6 sites in China
- Volunteers
- 1,300 people
- Sponsor
- Shandong University
Helicobacter Pylori Infection
Triple Therapy Versus Quadruple Therapies in the First Line Therapy of Helicobacter Pylori Infection
Whether non-bismuth quadruple therapy (concomitant therapy) is more effective than bismuth quadruple therapy or triple therapy for 14 days remains unknown.
- Trial name
- NCT01906879
- Testing
- triple, quadruple, non-bismuth quadruple therapy
- Where
- 10 sites in Taiwan
- Volunteers
- 1,620 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Multiple Myeloma
Autologous Stem Cell Transplant With Pomalidomide (CC-4047®) Maintenance Versus Continuous Clarithromycin/ Pomalidomide / Dexamethasone Salvage Therapy in Relapsed or Refractory Multiple Myeloma
The purpose of this study is to see whether pomalidomide (also known as Pomalyst) reduces the number of myeloma cells in the bones, and to see what is the best way to use pomalidomide in patients with myeloma.
- Trial name
- NCT01745588
- Testing
- Pomalidomide, stem cell, Dexamethasone
- Where
- 10 sites in United States
- Volunteers
- 23 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Lower Respiratory Tract Infection
Recovery Time in Children With Lower Respiratory Tract Infections Treated With Klacid® Granules for Oral Suspension.
Klacid Granules for Oral Suspension provides short symptoms' recovery time in Thai children with lower respiratory tract infections.
- Trial name
- NCT01076166
- Testing
- clarithromycin (Klacid) granules for oral suspension
- Where
- 16 sites in Thailand
- Volunteers
- 337 people
- Sponsor
- Abbott
Community Acquired Bacterial Pneumonia, Complicated Intra-Abdominal Infection
Study Evaluating Tigecycline Versus Ceftriaxone In Complicated Intra-Abdominal Infections & Community Acquired Pneumonia
The main purpose of this study is to compare the safety of tigecycline versus a ceftriaxone regimen in pediatric subjects (aged 8 to 17 years) with complicated intra-abdominal infections (cIAI) and community acquired pneumonia…
- Trial name
- NCT00914888
- Testing
- Tigecycline, cIAI: Ceftriaxone with metronidazole, plus if applicable aminoglycoside, CAP: Ceftriaxone, plus if applicable oral clarithromycin
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
H. Pylori Infection
Bismuth for PCAB-based H. Pylori Eradication
Tegoprazan is a new potassium-competitive acid blocker (PCAB) that has been clinically available since 2018 in South Korea. P-CAB is highly active drugs targeting H+, K+ -ATPase in the gastric acid secretion of parietal cells.
- Trial name
- NCT05453994
- Testing
- H. pylori eradication
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Soonchunhyang University Hospital
Lymphoma
Antibiotic Therapy in Treating Patients With Low Grade Gastric Lymphoma
RATIONALE: Antibiotics may stop the growth of Helicobacter pylori which may be associated with gastric lymphoma. PURPOSE: Phase II trial to study the effectiveness of antibiotic therapy in treating patients with low grade gastric…
- Trial name
- NCT00003151
- Testing
- bismuth subcitrate, amoxicillin, clarithromycin
- Where
- 22 sites in United Kingdom
- Volunteers
- 96 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
The Eradication Rate of Helicobacter Pylori
The Observation on the Efficacy of Dual Therapy Based on Vonoprazan in Eradicating Helicobacter Pylori
Helicobacter pylori（Hp）is listed as a Class 1 carcinogen by the International Agency for Research of Cancer (IARC), Eradicating Hp can significantly reduce the risk of gastric cancer.
- Trial name
- NCT06004401
- Testing
- Vonopazan +Amoxicillin, Rabeprazole +colloidal pectin bismuth +Amoxicillin +Clarithromycin, Vonopazan +Minocycline
- Volunteers
- 400 people
- Sponsor
- Shanghai Changzheng Hospital
Helicobacter Pylori Infection
Efficacy of Nitazoxanide Based Therapy vs Standard Triple Therapy in H-pylori in Children
This study aimed at comparing the efficacy of nitazoxanide-based triple therapy versus standard triple therapy for eradication of Helicobacter pylori infection in children at a tertiary care hospital.
- Trial name
- NCT07086937
- Testing
- Nitazoxanide, Metronidazole, PPI
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Muhammad Aamir Latif
Mycobacterium Avium-Intracellulare Infection, HIV Infections
A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or Placebo
To compare the efficacy of clarithromycin/ethambutol with placebo or with rifabutin at two different doses in reducing colony-forming units (CFUs) by 2 or more logarithms in patients with Mycobacterium avium Complex bacteremia…
- Trial name
- NCT00002101
- Testing
- Ethambutol hydrochloride, Clarithromycin, Rifabutin
- Where
- 44 sites in United States
- Volunteers
- 450 people
- Sponsor
- Pharmacia
Influenza A
Flufenamic Acid for Hospitalised Influenza Infection
It is well recognized that respiratory viruses cause substantial disease burden every year. Among all known respiratory viruses, influenza virus is the greatest cause of disability-adjusted life years lost, excess…
- Trial name
- NCT03238612
- Testing
- FFA, clarithromycin, oseltamivir, Oseltamivir alone
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Healthy
Clarithromycin 500 mg Tablets Under Fasting Conditions
This study will compare the relative bioavailability (rate and extent of absorption) of 500 mg Clarithromycin Tablets with that of 500 mg BIAXIN® Tablets following a single oral dose (1 x 500 mg tablet) in healthy adult subjects…
- Trial name
- NCT00835692
- Testing
- Clarithromycin, Biaxin®
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Helicobacter Pylori Infection
Development of Treatment Algorithm for Eradication of Helicobacter Pylori Based on Antibiotic Susceptibility Test
Helicobacter pylori eradication (H. pylori) rates with clarithromycin-based triple therapy are declining, and an alternative strategy is needed urgently.
- Trial name
- NCT02759029
- Testing
- eradication of Helicobacter pylori
- Where
- South Korea
- Volunteers
- 123 people
- Sponsor
- Gangnam Severance Hospital
Helicobacter Pylori Infection
Antibiotic Combination for H. Pylori Eradication in Penicillin-allergic Patients
This randomized controlled clinical trial will compare the eradication efficacy of bismuth quadruple therapy containing clarithromycin+metronidazole, clarithromycin+levofloxacin, or metronidazole+levofloxacin for Helicobacter…
- Trial name
- NCT05023577
- Testing
- Rabeprazole, Bismuth potassium citrate, Metronidazole
- Where
- China
- Volunteers
- 504 people
- Sponsor
- Shanghai Zhongshan Hospital
Helicobacter Infections, Stomach Neoplasms
Helicobacter Pylori Eradication to Prevent Gastric Cancer
Gastric cancer is the fourth most common type of cancer and the second leading cause of cancer-related death in the world. In China, more than 390,000 new patients are diagnosed with gastric cancer and more than 300,000 patients…
- Trial name
- NCT01133951
- Testing
- OAC triple therapy
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Jie-Jun Wang
Efficacy of Clarithromycin-Naproxen-Oseltamivir Combination Therapy vs. Oseltamivir Alone for Hospitalised Paediatric Influenza Patients
Efficacy of Clarithromycin-Naproxen-Oseltamivir Combination Therapy vs. Oseltamivir Alone for Hospitalised Paediatric Influenza Patients
Efficacy of clarithromycin-naproxen-oseltamivir combination therapy vs. oseltamivir alone for hospitalised paediatric influenza patients
- Trial name
- NCT04315194
- Testing
- clarithromycin-naproxen-oseltamivir
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- Mackay Memorial Hospital
HIV Infections
An Open-Label Study in HIV+ Patients to Determine the Effects of Nevirapine (Viramune) on the Pharmacokinetics of Clarithromycin and Activity of Cytochrome 3A4.
To evaluate the potential pharmacokinetic interaction between nevirapine and clarithromycin, and to determine the effects of nevirapine on cytochrome P450 3A4 (CYP3A4) activity in vivo.
- Trial name
- NCT00002194
- Testing
- Erythromycin, Nevirapine, Clarithromycin
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Boehringer Ingelheim
Helicobacter Pylori Eradication
Potassium Copetitive Acid Blockers Efficacy in H.Pylori Eradication
This trial assessed the efficacy of potassium competetor acid blocker (P-CAB) in the eradication of H.pylori
- Trial name
- P-CABs (NCT06101420)
- Testing
- Vonoprazan
- Where
- Egypt
- Volunteers
- 232 people
- Sponsor
- Ain Shams University