Clinical trials: Clarithromycin
Healthy Adults
A Study to Learn if Study Medicines Called Cyclosporine and Clarithromycin Affect How the Body Processes the Other Study Medicine Called PF-07328948 in Healthy Adults
The purpose of this study is to learn about the effect of cyclosporine, an immunosuppressant (medicine that suppresses the immune system), on the pharmacokinetics (PK) of PF-07328948 in healthy participants (Part A).
- Trial name
- NCT06837259
- Testing
- PF-07328948, cyclosporine, clarithromycin
- Where
- Belgium
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Pfizer
Helicobacter Pylori Infection
The Efficacy of Quadruple Therapy Containing Sodium Bicarbonate as the Primary Treatment for Helicobacter Pylori Infection
The goal of this clinical trial is to learn the efficacy of sodium bicarbonate-containing quadruple therapy as the primary treatment for Helicobacter pylori infection.
- Trial name
- NCT06591494
- Testing
- Classic quadruple therapy, Quadruple therapy with sodium bicarbonate instead of bismuth, Quadruple therapy with sodium bicarbonate instead of clarithromycin
- Volunteers
- 855 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ulcer
H. Pylori Eradication on Healing of Iatrogenic Gastric Ulcer by Endoscopic Mucosal Resection
This study will evaluate the effect of Helicobacter pylori eradication therapy on the healing of iatrogenic gastric ulcer caused by endoscopic mucosal resection of gastric neoplastic lesions and is a multicenter, randomized…
- Trial name
- NCT00926809
- Testing
- Lansoprazole (proton pump inhibitor), amoxicillin, clarythromycin
- Where
- 6 sites in South Korea
- Volunteers
- 232 people
- Sponsor
- Korean College of Helicobacter and Upper Gastrointestinal Research
Helicobacter Pylori Infection
Vonoprazan in Helicobacter Pylori Treatment an RCT
RCT for comparison of Standard Triple therapy (Omeprazole+Amoxil+Clarithromycin) for H Pylori erradication with Vonoprazan+Amoxil dual therapy.
- Trial name
- NCT04901663
- Testing
- Omeprazole 20 MG Capsule; Amoxicillin 1000 MG; Clarithromycin 500 MG, Vonoprazan 20 MG; Amoxicillin 1000 MG
- Where
- Pakistan
- Volunteers
- 179 people
- Sponsor
- Dow University of Health Sciences
Gastritis, Indigestion, Helicobacter Pylori Infection, Gastric Cancer, Peptic Ulcer
Efficacy Comparison of Vonoprazan Combined With Different Antibiotics in Dual Therapy for Helicobacter Pylori Eradication: A Prospective, Randomized Controlled Clinical Trial
This study aims to evaluate the efficacy of vonoprazan combined with different antibiotics in dual therapy for Helicobacter pylori eradication treatment.
- Trial name
- NCT07068607
- Testing
- Vonoprazan, Tetracycline 500mg tid, Minocycline
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Yongquan Shi
Multiple Organ Dysfunction
Modulation of Microbiota Metabolism in Cardiac Surgery Patients
An imbalance in the microbiota (most often intestinal) largely determines the onset of a disease state, and often a critical state.
- Trial name
- MMMMODCS (NCT04921436)
- Testing
- cardiac surgery
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Petrovsky National Research Centre of Surgery
Bacterial Pneumonia
Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia
The purpose of this study is to determine whether ceftaroline is effective and safe in the treatment of Community-Acquired Pneumonia
- Trial name
- CAP (NCT00621504)
- Testing
- Ceftaroline fosamil for Injection, IV Ceftriaxone, Clarithromycin
- Where
- 168 sites in United States, Argentina and 21 more
- Volunteers
- 606 people
- Sponsor
- Forest Laboratories
Helicobacter Pylori Infection
Community-based Helicobacter Pylori Eradication
Based on a universal eradication of H. pylori in an offshore island (Matsu) with a high prevalence of gastric cancer as well as premalignant gastric lesion, we first examined the infection rate of H. pylori.
- Trial name
- NCT00155389
- Testing
- Helicobacter pylori eradication
- Where
- 2 sites in Taiwan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
H. Pylori Infection
Efficacy of 10-day and 14-day Sequential Therapy Versus Triple Therapy on the Eradication of Helicobacter Pylori
Background: Helicobacter pylori infection has been shown to be associated with the development of gastric cancer and peptic ulcer diseases. Eradication of H.
- Trial name
- NCT01042184
- Testing
- Sequential therapy for 14 days, Sequential therapy for 10 days, Triple therapy for 14 days
- Where
- Taiwan
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Immune Thrombocytopenia
Effects of Helicobacter Pylori Eradication in Children With Chronic Immune Thrombocytopenic Purpura
Thrombocytopenia refers to a reduction in platelet count to (<150 × 109/L). Immune thrombocytopenic purpura is an acquired autoimmune disorder defined by isolated thrombocytopenia and the exclusion of other causes of…
- Trial name
- NCT03172676
- Testing
- Amoxicillin 50 mg/kg/day in 2 divided doses for 14 days., Clarithromycin 15 mg/kg/day in 2 divided doses for 14 days., Proton pump inhibitor 1 mg/kg/day in 2 divided doses 1 month
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Assiut University
Helicobacter Pylori Infection
Evaluation of Saccharomyces Boulardii Combined With Standard Quadruple Therapy for Eradication of Helicobacter Pylori
The eradication rate of standard quadruple therapy has become less successful due to low compliance and high resistance to the antibiotics.
- Trial name
- NCT03688828
- Testing
- Saccharomyces boulardii, Esomeprazole, Amoxicillin
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Huazhong University of Science and Technology
Multiple Myeloma
Carfilzomib, Clarithromycin (Biaxin®), Lenalidomide (Revlimid®), and Dexamethasone (Decadron®) [Car-BiRD] Therapy for Subjects With Multiple Myeloma
The purpose of this study is to evaluate the safety and effectiveness of an investigational new drug called carfilzomib, in combination with dexamethasone in subjects with newly diagnosed multiple myeloma followed by treatment…
- Trial name
- CarBiRD (NCT01559935)
- Testing
- carfilzomib, Dexamethasone, Clarithromycin
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Weill Medical College of Cornell University
Sepsis, Severe Sepsis
Clarithromycin as Immunomodulator for the Management of Sepsis
The herein protocol is based on the results of one former clinical trial conducted by our study group showing the considerable efficacy of intravenously administered clarithromycin as an adjuvant to antimicrobial chemotherapy for…
- Conditions
- Sepsis, Severe Sepsis, Septic Shock
- Trial name
- NCT01223690
- Testing
- Clarithromycin, Dextrose 5%
- Where
- 6 sites in Greece
- Volunteers
- 600 people
- Sponsor
- University of Athens
Helicobacter Infections, Gastritis
Second Line Therapy for the Cure of Helicobacter Pylori (H. Pylori) Infection
Proton pump inhibitors (PPIs) are mainly metabolized in the liver by CYP2C19, one of the cytochrome P450 isoenzymes, which shows a genetic polymorphism associated with enzyme activities. The most essential role of a PPI in H.
- Conditions
- Helicobacter Infections, Gastritis, Gastric Ulcer, Duodenal Ulcer
- Trial name
- NCT00197418
- Testing
- rabeprazole, amoxicillin, clarithromycin, metronidazole
- Where
- Japan
- Sponsor
- Hamamatsu University
Helicobacter Pylori Infection
Comparison Between Ten Days Sequential Treatment and Traditional Three Combined Treatment of Helicobacter Pylori
The purpose of this study is to compare the eradication efficacy of 10-day triple therapy with 10-day sequential therapy with tetracycline or metronidazole.
- Trial name
- NCT01573975
- Testing
- 5RA-5RCM, 5RA-5RCT, 10RCA
- Where
- Taiwan
- Volunteers
- 345 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Helicobacter Pylori Infection
Comparison Between Quadruple Regimens for Helicobacter Pylori Infection in Egypt
The overall prevalence of H. Pylori in the developing countries is 50.8%, with the highest one presented in Africa (79.1%). Hybrid therapy is supposed to be more effective as a first-line regimen for Helicobacter pylori infection…
- Trial name
- NCT04039412
- Testing
- Hybrid regimen, Reverse hybrid regimen, Levofloxacin quadruple regimen
- Where
- Egypt
- Volunteers
- 330 people
- Sponsor
- Ayman Magd Eldin Mohammad Sadek
Gastric Diffuse Large B-cell Lymphoma
First-line Antibiotic Therapy for Early-stage HP(+) Gastric Pure DLBCL
Aims: A nationwide study to prospectively validate 1. The complete histological and molecular remission rate for antibiotics as 1st-line therapy for early-stage Hp-positive gastric pure (de novo) DLBCL 2.
- Trial name
- NCT02388581
- Testing
- Lansoprazole, Amoxicillin, Clarithromycin, Metronidazole
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Health Research Institutes, Taiwan
Mycobacterium Avium-intracellulare Infection, HIV Infections
The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDS
To evaluate three doses of clarithromycin in children with AIDS and Mycobacterium avium complex (MAC) infection who are receiving concurrent antiretroviral therapy.
- Trial name
- NCT00000971
- Testing
- Clarithromycin, Zidovudine, Didanosine
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Abbott
Lyme Disease, Borrelia Infection
Persistent Lyme Empiric Antibiotic Study Europe
The purpose of the study is to establish whether prolonged antibiotic treatment of patients diagnosed with proven or presumed PLD (as endorsed by the international ILADS guidelines) leads to better patient outcome than short-term…
- Trial name
- PLEASE (NCT01207739)
- Testing
- Doxycycline, Clarithromycin and hydroxychloroquine
- Where
- 2 sites in Netherlands
- Volunteers
- 280 people
- Sponsor
- Radboud University Medical Center
Helicobacter Pylori Infection
Efficacy of Low-dose Vonoprazan for Helicobacter Pylori Eradication
The primary objective of this retrospective study was to assess the efficacy and safety of a bismuth quadruple regimen of a low-dose potassium-competitive acid blocker versus a standard-dose potassium-competitive acid blocker and…
- Trial name
- NCT06037122
- Volunteers
- 558 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine