Clinical trials: Clarithromycin, completed
Multidrug-resistant Tuberculosis, Extensively Drug-resistant Tuberculosis
Drug Interaction Study Between Linezolid and Clarithromycin in Tuberculosis Patients
Future patients might benefit from a combination of linezolid (LIN) and clarithromycin (CLA) in the treatment of Multidrug-resistant and Extensively Drug-resistant Tuberculosis (MDR/XDR-TB) due to possible synergistic activity as…
- Trial name
- NCT01521364
- Testing
- Addition of different doses of clarithromycin.
- Where
- Netherlands
- Volunteers
- 7 people
- Sponsor
- University Medical Center Groningen
Helicobacter Pylori Infection
Impact of Periodontal Treatment on Gastric Helicobacter Pylori Eradication
The efficacy of conventional systemic antibiotic therapy for eradication of gastric H. pylori has been seriously challenged by antibiotic resistance.
- Trial name
- NCT03654781
- Testing
- Triple therapy, professional periodontal treatment
- Volunteers
- 98 people
- Sponsor
- Ondokuz Mayıs University
Mucosa Associated Lymphoid Tissue (MALT) Lymphoma
Clarithromycin + Lenalidomide Combination: a Full Oral Treatment for Patients With Relapsed/Refractory Extranodal Marginal Zone Lymphoma
Patients with lymphoid tissue lymphoma mucosa-associated (MALT) for which the standard treatments with radiotherapy, chemotherapy and / or immunotherapy show lack of efficacy
- Trial name
- NCT03031483
- Testing
- clarithromycin and lenalidomide
- Where
- 10 sites in Austria, Italy and 1 more
- Volunteers
- 44 people
- Sponsor
- International Extranodal Lymphoma Study Group (IELSG)
Healthy Volunteers
A Study to Investigate Effect of Clarithromycin, a Strong CYP3A4 Inhibitor, on Brensocatib Pharmacokinetics in Healthy Participants
The primary purpose of this study is to determine the effect of clarithromycin on the single-dose pharmacokinetics (PK) of brensocatib in healthy participants.
- Trial name
- NCT05965570
- Testing
- Brensocatib, Clarithromycin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Insmed Incorporated
Optimization of Second Line Treatment Protocol for H Pylori Eradication
Sequential Therapy Versus Quadruple Therapy as Second Line Treatment After Failure of the Standard Triple Therapy for H Pylori Infection
The aim of this study is to evaluate the efficacy of sequential therapy, i.e. 5 days of PPI + amoxicillin followed by 5 days of PPI + two antimicrobial drugs( clarithromycin and tinidazole ) versus quadruple drug regimen( i.e.-14…
- Trial name
- NCT01481844
- Testing
- Lansoprazole , Tab Amoxycillin , Tab Clarithromycin ,Tab Tinidazole, Lansoprazole, Bismuth Subsalicylate, Metronidazole, Tetracycline
- Where
- Israel
- Volunteers
- 101 people
- Sponsor
- Soroka University Medical Center
Multiple Myeloma and Plasma Cell Neoplasm
Chemoprevention Therapy in Treating Patients at High Risk of Developing Multiple Myeloma
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. Dehydroepiandrosterone and clarithromycin may be effective in preventing multiple myeloma.
- Trial name
- NCT00006219
- Testing
- clarithromycin, prasterone
- Where
- 3 sites in United States
- Sponsor
- Mayo Clinic
Healthy Volunteers
Dabigatran in an Interaction Probe Drug Cocktail
Four periods of oral dosing following overnight fasting (1. known metabolic probe drug cocktail consisting of caffeine, diclofenac, esomeprazole, metoprolol, midazolam; 2. dabigatran + cocktail; 3. dabigatran alone; 4.
- Trial name
- D-cocktail (NCT02361619)
- Testing
- Caffeine, Diclofenac, Esomeprazole
- Where
- Finland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Gastric Tumor, Helicobacter Pylori
Helicobacter Pylori Eradication After Endoscopic Resection of Gastric Tumors
The purpose of this study is to determine whether Helicobacter pylori eradication could reduce the new tumor development after endoscopic resection of gastric tumor.
- Conditions
- Gastric Tumor, Helicobacter Pylori, Endoscopic Resection, Metachronous Neoplasms
- Trial name
- NCT01510730
- Testing
- eradication treatment of Helicobacter pylori infection
- Where
- South Korea
- Volunteers
- 855 people
- Sponsor
- Seoul National University Hospital
Mycobacterium Avium Complex Lung Disease
Use of Clarithromycin and Rifabutin for the Treatment of M. Avium Complex (MAC) Lung Disease
To determine the safety and tolerance of clarithromycin given three times per week in combination with multiple drugs including rifabutin three times per week
- Trial name
- NCT00598897
- Testing
- clarithromycin, rifabutin
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- The University of Texas Health Science Center at Tyler
Helicobacter Pylori Infection
Comparison of 12-day Reverse Hybrid Therapy and 12-day Standard Triple Therapy for Helicobacter Pylori Infection
Reverse hybrid therapy is a one-step two-phase treatment for Helicobacter pylori infection with less cost than standard triple therapy.
- Trial name
- REHYTRI (NCT02359435)
- Testing
- Reverse hybrid therapy, Standard triple therapy
- Where
- Taiwan
- Volunteers
- 440 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Helicobacter Pylori Infection, Gastritis
7 Days vs. 14 Days of Vonoprazan-based Triple Therapy for H. Pylori Eradication
The study aims to test the efficacy of 7 days vs. 14 days of Vonoprazan-triple therapy in the eradication of Helicobacter Pylori infection in adolescents and young children.
- Conditions
- Helicobacter Pylori Infection, Gastritis, Vonoprazan, Adolescents
- Trial name
- VOTE-HP (NCT06576882)
- Testing
- Vonoprazan, Amoxicillin, Clarithromycin
- Where
- Egypt
- Volunteers
- 326 people
- Sponsor
- Alexandria University
Healthy Volunteers, Patients
Drug Interaction Study on Linaprazan Glurate Capsules
This study is a drug-drug interaction (DDI) investigation involving Linaprazan Glurate capsules and a combination of clarithromycin tablets, amoxicillin capsules, and bismuth potassium citrate capsules.
- Trial name
- NCT07294846
- Testing
- Linaprazan Glurate Capsules, Bismuth Potassium Citrate Capsules, Amoxicillin Capsules
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Jiangsu Sinorda Biomedicine Co., Ltd
Infection
Bioequivalency Study of Clarithromycin Tablets Under Fasting Conditions
The objective of this study was the bioequivalence of a potential generic 250 mg clarithromycin tablet formulation compared with Abbott Laboratories 250 mg clarithromycin tablet, Biaxin® following a single 250 mg dose…
- Trial name
- NCT00601315
- Testing
- Clarithromycin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Helicobacter Pylori Infection, Helicobacter Pylori gyrA Levofloxacin Resistance Mutation
Helicobacter Pylori 23S rRNA/gyrA Gene Mutation Detection Kit (Fluorescence PCR Fusion Curve Method)
The purpose of this study was to evaluate the detection ability of Helicobacter pylori 23S rRNA/gyrA gene mutation detection kit (fluorescent PCR fusion curve method) for Helicobacter pylori gene mutation.
- Conditions
- Helicobacter Pylori Infection, Helicobacter Pylori gyrA Levofloxacin Resistance Mutation, Fecal Drug Resistance Gene Detection, Helicobacter Pylori Infection, Susceptibility to
- Trial name
- NCT05410652
- Testing
- Detection of fecal samples with diagnostic kit, Sanger Sequencing group, Bacterial culture and drug sensitivity test of gastric mucosa samples
- Where
- 4 sites in China
- Volunteers
- 1,176 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Pneumonia
A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Clarithromycin Extended Release for the Treatment of Pneumonia in Adult Patients
The study was performed to confirm that a single, 2.0 g oral dose of azithromycin sustained release (SR) at least as effective as 7 days of clarithromycin extended release (ER), 1.0 g by mouth once daily, when used to treat…
- Trial name
- NCT00643227
- Testing
- clarithromycin extended release (ER), azithromycin SR
- Where
- 72 sites in United States, Argentina and 5 more
- Volunteers
- 504 people
- Sponsor
- Pfizer
Helicobacter Pylori Infection
Comparison of Therapy in Treatment of Patients With Helicobacter Pylori Infection: Concomitant Versus Hybrid Therapy.
The aim of the study is to compare the effectiveness of two therapeutic protocols in the treatment of Helicobacter pylori infection.
- Trial name
- NCT03572777
- Testing
- Concomitant therapy, Hybrid therapy
- Where
- Croatia
- Volunteers
- 159 people
- Sponsor
- Antonio Mestrovic
Gastritis H Pylori
14-day Quadruple Therapy Versus Triple Therapy in HP Eradication
In this prospective randomized-controlled study, treatment-naive H. pylori-infected patients are randomized to receive either standard triple therapy or sequential therapy.
- Trial name
- HEPRA (NCT04769583)
- Testing
- metronidazole based quadriple therapy
- Where
- Tunisia
- Volunteers
- 121 people
- Sponsor
- mohamed bouchoucha
Helicobacter Pylori Infection
Sequential and Hybrid Therapies for H Pylori Infection
Primary: To evaluate efficacy of 14 day 2-phase sequential therapy given in two forms. One in which the first component consists of a proton pump inhibitor and amoxicillin given for 7 days followed by the PPI, clarithromycin and…
- Trial name
- NCT01085786
- Testing
- 14-day sequential treatment, 14-day hybrid treatment
- Where
- 2 sites in Taiwan
- Volunteers
- 240 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Dyspepsia, Helicobacter Pylori Infection
Helicobacter Pylori Eradication in Functional Dyspepsia
This study is designed to study benefit of eradicating Helicobacter Pylori in patients with functional dyspepsia as compared to symptomatic treatment only.
- Trial name
- NCT04697641
- Testing
- Clarithromycin 500mg, Amoxicillin 1000 MG, Pantoprazole 40mg
- Where
- India
- Volunteers
- 202 people
- Sponsor
- Sir Ganga Ram Hospital
Functional Dyspepsia, Helicobacter Pylori Infection
Effect of Eradication of Helicobacter Pylori on the Dyspeptic Symptoms
Helicobacter pylori eradication and its impact on symptoms in patients with non-ulcer dyspepsia remain controversial . Many studies have examined the effect of H.
- Trial name
- EEHPDS (NCT00772837)
- Testing
- Omeprazole + Clarithromycin + Amoxycillin
- Where
- Pakistan
- Volunteers
- 370 people
- Sponsor
- Aga Khan University