Clinical trials: Clarithromycin
Helicobacter Pylori Infection
Comparison of Therapy in Treatment of Patients With Helicobacter Pylori Infection: Concomitant Versus Hybrid Therapy.
The aim of the study is to compare the effectiveness of two therapeutic protocols in the treatment of Helicobacter pylori infection.
- Trial name
- NCT03572777
- Testing
- Concomitant therapy, Hybrid therapy
- Where
- Croatia
- Volunteers
- 159 people
- Sponsor
- Antonio Mestrovic
Helicobacter Pylori Infection
Efficacies of Susceptibility-guided vs Empiric Therapy for Rescue Treatment of Helicobacter Pylori Infection
The prevalence of H. pylori antibiotic resistance has reached an alarming level worldwide. Antibiotic stewardship programs should be urgently developed and implemented. However, H.
- Trial name
- NCT05332444
- Testing
- susceptibility-guided tailored therapy (Group A), guidelines-recommended empiric therapy (Group B)
- Where
- Taiwan
- Volunteers
- 450 people
- Sponsor
- National Taiwan University Hospital
Immune Thrombocytopenic Purpura
Helicobacter Pylori Immune Thrombocytopenic Purpura
We designed a study for evaluate the efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenic purpura (ITP) patients with moderate thrombocytopenia.
- Trial name
- HpyloriITP (NCT01255332)
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Cooperative Study Group A for Hematology
Gastritis H Pylori
14-day Quadruple Therapy Versus Triple Therapy in HP Eradication
In this prospective randomized-controlled study, treatment-naive H. pylori-infected patients are randomized to receive either standard triple therapy or sequential therapy.
- Trial name
- HEPRA (NCT04769583)
- Testing
- metronidazole based quadriple therapy
- Where
- Tunisia
- Volunteers
- 121 people
- Sponsor
- mohamed bouchoucha
Helicobacter Pylori Infection
Sequential and Hybrid Therapies for H Pylori Infection
Primary: To evaluate efficacy of 14 day 2-phase sequential therapy given in two forms. One in which the first component consists of a proton pump inhibitor and amoxicillin given for 7 days followed by the PPI, clarithromycin and…
- Trial name
- NCT01085786
- Testing
- 14-day sequential treatment, 14-day hybrid treatment
- Where
- 2 sites in Taiwan
- Volunteers
- 240 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Dyspepsia, Helicobacter Pylori Infection
Helicobacter Pylori Eradication in Functional Dyspepsia
This study is designed to study benefit of eradicating Helicobacter Pylori in patients with functional dyspepsia as compared to symptomatic treatment only.
- Trial name
- NCT04697641
- Testing
- Clarithromycin 500mg, Amoxicillin 1000 MG, Pantoprazole 40mg
- Where
- India
- Volunteers
- 202 people
- Sponsor
- Sir Ganga Ram Hospital
Functional Dyspepsia, Helicobacter Pylori Infection
Effect of Eradication of Helicobacter Pylori on the Dyspeptic Symptoms
Helicobacter pylori eradication and its impact on symptoms in patients with non-ulcer dyspepsia remain controversial . Many studies have examined the effect of H.
- Trial name
- EEHPDS (NCT00772837)
- Testing
- Omeprazole + Clarithromycin + Amoxycillin
- Where
- Pakistan
- Volunteers
- 370 people
- Sponsor
- Aga Khan University
COVID-19
Isotretinoin in Treatment of COVID-19
Contributors: Lamia Elgarhy, Sabah El-Gaeish 1, Eman Hamed 2 , Wagdy Fathy2 Department of Dermatology, Department of Pharmacology1 , Faculty of Medicine, Tanta University, Department of Chest, Faculty of Medicine, Suez Canal…
- Trial name
- Randomized (NCT04361422)
- Testing
- Isotretinoin Only Product in Oral Dose Form
- Volunteers
- 300 people
- Sponsor
- Tanta University
Mycobacterium Avium-intracellular Infection, HIV Infections
The Safety and Effectiveness of Clarithromycin Plus Ethambutol Used With or Without Clofazimine in the Treatment of MAC in Patients With AIDS
PRIMARY: To assess the tolerability of the combination regimen of clarithromycin plus ethambutol with or without clofazimine in patients with disseminated Mycobacterium avium Complex (dMAC).
- Trial name
- NCT00002331
- Testing
- Ethambutol hydrochloride, Clarithromycin, Clofazimine
- Where
- 18 sites in United States, Puerto Rico
- Sponsor
- Abbott
H.Pylori, Gastric Cancer
Helicobacter Pylori Infection and Gastric Disease in Bhutan: First Community-Wide, Population-Based Study
Background: Helicobacter pylori is a major risk factor for gastric cancer, yet in many developing countries, including Bhutan where gastric cancer incidence is high, access to screening and eradication is limited.
- Conditions
- H.Pylori, Gastric Cancer, H Pylori Eradication
- Trial name
- NCT07211880
- Testing
- Rabeprazole Sodium, Amoxicillin Hydrate, Clarithromycin, Upper gastrointestinal endoscopy for the H. pylori and serum pepsinogen positive individuals (high risk group of gastric cancer), Urea Breath Test for the prevalence of H pylori
- Where
- Bhutan
- Volunteers
- 1,043 people, healthy volunteers welcome
- Sponsor
- Zero Helicobacter IGAN Network
Healthy
A Study to Assess the Drug-Drug Interaction Between Bedaquiline and Clarithromycin in Healthy Adult Participants
The purpose of this study is to assess the effect of steady-state clarithromycin once every 12 hour on the pharmacokinetic parameters of bedaquiline and its active metabolite M2 after a single dose of bedaquiline.
- Trial name
- NCT03800550
- Testing
- Bedaquiline, Clarithromycin
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Helicobacter Pylori Infection
Efficacy and Safety Study of Egg Yolk Antibody in Adjuvant Treatment of Helicobacter Pylori Infection
Helicobacter pylori is an important pathogenic factor for gastrointestinal diseases such as gastritis, peptic ulcer, gastric mucosa-associated lymphoid tissue lymphoma and gastric cancer.However, with the increasing use of…
- Trial name
- NCT05410223
- Testing
- Yolk antibody and IIaprazole, Amoxicillin/ Clarithromycin/Furazolidone, Doxycycline, Bismuth, IIaprazole, Amoxicillin/Clarithromycin/Furazolidone, Doxycycline, Bismuth, Yolk antibody and IIaprazole, Amoxicillin/ Clarithromycin/Furazolidone, Doxycycline
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Epilepsy, Generalized, Helicobacter Pylori Infection
Helicobacter Pylori Eradication Therapy for Epileptic Children
Helicobacter pylori (H. pylori) infection is associated with several health problems. The role of H. pylori infection in epilepsy has been investigated in a few studies.
- Trial name
- NCT05297695
- Testing
- Triple therapy for H. pylori infection
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Sohag University
Helicobacter Pylori Infection
Feasibility Study of the Proposed Test-and-treat Screening Program in Younger Participants With H. Pylori Infection
This prospective non-interventional study is being conducted as part of the EU4Health project Eurohelican. The main goal of this pilot study is to evaluate the feasibility and acceptability of implementing the proposed…
- Trial name
- NCT06216639
- Testing
- Bismuth Subcitrate, Esomeprazole, Metronidazole
- Where
- Slovenia
- Volunteers
- 2,000 people
- Sponsor
- National Institute of Public Health, Slovenia
Helicobacter Pylori Infection
The Evaluation of Triple Therapy With Vonoprazan, Amoxicillin and Bismuth for Eradication of Helicobacter Pylori
The eradication rate of standard quadruple therapy has become less successful due to low compliance and high resistance to antibiotics.
- Trial name
- NCT05189444
- Testing
- Vonoprazan, Amoxicillin, Esomeprazole
- Where
- China
- Volunteers
- 672 people
- Sponsor
- Huazhong University of Science and Technology
Community-acquired Pneumonia
Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT)
The primary objective of the REACT randomized clinical trial (RCT) is to optimize the clinical benefit from adjunctive clarithromycin treatment shown in the ACCESS trial and to provide evidence for the clinical benefit of early…
- Trial name
- REACT (NCT06294600)
- Testing
- Clarithromycin 500mg, Tablets
- Where
- 24 sites in Greece
- Volunteers
- 330 people
- Sponsor
- Hellenic Institute for the Study of Sepsis
Preterm Premature Rupture of Membrane
Duration of Antibiotics Treatment With Cefazolin and Clarithromycin in Women With Preterm Premature Rupture of Membrane
The purpose of this study is to compare the neonatal outcome and infant neurologic outcome whose mother were treated with cefazolin plus clarithromycin for one week or until delivery after preterm premature rupture of membrane.
- Trial name
- NCT01503606
- Testing
- Cefazolin, Clarithromycin
- Where
- South Korea
- Volunteers
- 151 people
- Sponsor
- Samsung Medical Center
Helicobacter Pylori Infection
Efficacy and Safety of 14-day Concomitant Therapy for Helicobacter Pylori Infection
The purpose of this study is to evaluate efficacy of a 14-day concomitant therapy for the third-line treatment of Helicobacter pylori infection, and whether it is safe while maintaining an ideal eradication rates.
- Trial name
- NCT04991584
- Testing
- Amoxicillin,Tetracycline,Furazolidone,Levofloxacin,Vonoprazan fumarate, Esomeprazole ,
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shandong University
Community-acquired Pneumonia, Sepsis
Anti-inflammatory Action of Oral Clarithromycin in Community-acquired Pneumonia
Traditional management of community-acquired pneumonia (CAP) relies on the prompt administration of antimicrobials that target the most common causative pathogens.
- Conditions
- Community-acquired Pneumonia, Sepsis, Inflammatory Response, Mortality
- Trial name
- ACCESS (NCT04724044)
- Testing
- Tablets, Clarithromycin 500mg
- Where
- 18 sites in Greece
- Volunteers
- 278 people
- Sponsor
- Hellenic Institute for the Study of Sepsis
Respiratory Tract Infection
Clarithromycin Modified Release Observational Study for Evaluation of Treatment, Tolerability & Recovery Time in Saudi & Egyptian Clinical Settings (CLOSER)
The objective is to describe the time to recovery of symptoms (cough, mucus, fever, sore throat, and others), tolerability and compliance of treatment with clarithromycin once daily in patients with upper or lower respiratory…
- Trial name
- CLOSER (NCT01075204)
- Testing
- clarithromycin modified release 500 mg
- Where
- 12 sites in Egypt, Saudi Arabia
- Volunteers
- 335 people
- Sponsor
- Abbott