Clinical trials: Conventional Physical Therapy
Chronic Low-Back Pain, Refractory Pain
Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)
The objective of this study is to evaluate the efficacy of BurstDR dorsal column stimulation, compared with conventional medical management, in improving pain and back-related physical function in subjects suffering with chronic…
- Conditions
- Chronic Low-Back Pain, Refractory Pain, Neuropathic Pain
- Trial name
- NCT04479787
- Testing
- Spinal Cord Stimulation, Conventional Medical Management
- Where
- 30 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Devices
Schizophrenia, Psychosis
The Sub-Sero Study
Schizophrenia is a severe, often chronic mental disorder, characterized by positive and negative symptoms and cognitive deficits.
- Trial name
- NCT03994965
- Testing
- Pimavanserin 34 milligrams (MG) [Nuplazid]
- Sponsor
- Bjorn H. Ebdrup
Stroke
Effect of Personalized Robotic Therapy
The primary goal of this project is to test the safeness and clinical effectiveness of a novel exoskeleton for the upper limb (Arm Light Exoskeleton Rehab Station, ALEx RS) developed at Wearable Robotics srl, for the force…
- Trial name
- NCT02770300
- Testing
- Arm Light Exoskeleton Rehab Station (ALEx RS), Arm Light Exoskeleton Rehab Station (ALEx RS) - automatically personalized
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Wearable Robotics srl.
Ataxic Cerebral Palsy
Effects of VOJTA Technique on Ataxic Cerebral Palsy.
Ataxic cerebral palsy (CP) is the least common subtype of CP and it is primarily caused by cerebellar damage that results in hypotonia, impaired balance, poor coordination, tremors, wide-based gait, and significant difficulties…
- Trial name
- NCT07291128
- Testing
- VOJTA, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Lahore University of Biological and Applied Sciences
AL Amyloidosis (AL), t(11;14) Positive
Sonrotoclax Plus Dexamethasone With or Without Daratumumab Regimen in Patients With t(11;14) Primary AL Amyloidosis
The goal of this study is to evaluate the efficacy and safety of Sonrotoclax combined Regimen in patients with t(11;14) AL amyloidosis.
- Trial name
- NCT07335887
- Testing
- sonrotoclax, Daratumumab, Dexamethasone
- Where
- 3 sites in China
- Volunteers
- 39 people
- Sponsor
- Peking University People's Hospital
Ischemic Stroke, Hemorrhagic Stroke
BCI-FES Therapy for Stroke Rehabilitation
There are over 7 million stroke survivors in the US alone, with approximately 795,000 new cases annually. Despite the best available physiotherapy, 30-60% of stroke survivors remain affected by difficulty walking, with foot…
- Trial name
- NCT04279067
- Testing
- BCI-FES dorsiflexion therapy, Physiotherapy one hour, Physiotherapy two hours
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, Irvine
Spinal Cord Injury
Effects of Lokomat Training on Dynamic Postural Stability in Incomplete Spinal Cord Injury
The study aims to evaluate the effects of robotic-assisted gait training (Lokomat) on dynamic postural stability in patients with incomplete spinal cord injury (SCI).
- Trial name
- NCT07621900
- Testing
- Robotic Rehabilitation, Control
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Balance, Stroke
Immersive Virtual Reality in Post Stroke
Physiotherapy intervention programs in the post-stroke patient should develop strategies to assess functional deficit, prevent poorly adaptive plasticity and maximize functional gain.
- Conditions
- Balance, Stroke, Physical Therapy, Virtual Reality
- Trial name
- NCT04379687
- Testing
- Virtual reality, Control group
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Yolanda Marcen Roman
Ankle Injuries
Does Performing a Composite Test 3 Months Post-operatively Reduce the Risk of Failure to Return to Sport After Lateral Ankle Ligamentoplasty?
Ankle sprain is one of the most common pathologies in the general population (between 2.1 and 3.2 per 1000 patients per year). Nearly 40% of patients will develop chronic instability in the year following the sprain.
- Trial name
- NCT06395714
- Testing
- Personnalized physiotherapy, Usual physiotherapy
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Lumbar Radiculopathy
Effects of ELDOA in Lumber Radiculopathy
ELDOA is the most beneficial intervention treating for lumbar pathologies such as radiculopathy. This study was a randomized control trial in which data was collected from Riphah Rehabilitation and Research Centre and Pakistan…
- Trial name
- NCT04681716
- Testing
- ELDOA, CONVENTIONAL PHYSIOTHERAPY
- Where
- Pakistan
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aqua Medical Services (Pvt) Ltd
Cervical Carcinoma, Esophageal Carcinoma
Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma
This randomized phase II trial studies how well nivolumab or expectant observation following ipilimumab, nivolumab, and surgery work in treating patients with high-risk mucosal melanoma that is restricted to the site of origin…
- Conditions
- Cervical Carcinoma, Esophageal Carcinoma, Mucosal Melanoma, Mucosal Melanoma of the Head and Neck
- Trial name
- NCT03220009
- Testing
- Conventional Surgery, Ipilimumab, Laboratory Biomarker Analysis
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Cerebral Palsy
Effects of Robotic Gait, Hydrotherapy, and Conventional Physiotherapy in Spastic Hemiparetic CP
This study aims to evaluate the effects of three different physiotherapy approaches-robot-assisted gait training, hydrotherapy, and conventional physiotherapy-on muscle strength, balance, functional mobility, and psychological…
- Trial name
- NCT07031609
- Testing
- Robot-assisted gait training using Lokomat, Hydrotherapy, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Arel University
Breast Cancer
Surgical Resection With or Without Axillary Lymph Node Dissection in Treating Women With Node-Negative Breast Cancer and Sentinel Lymph Node Micrometastases
RATIONALE: Surgery to remove lymph nodes in the armpit in patients with sentinel lymph node micrometastases may remove cancer cells that have spread from tumors in the breast.
- Trial name
- 23-01 (NCT00072293)
- Testing
- Axillary lymph node dissection, No axillary lymph node dissection
- Where
- 31 sites in Australia, Belgium and 8 more
- Volunteers
- 931 people
- Sponsor
- ETOP IBCSG Partners Foundation
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy
This is a non-randomized, open-label phase II clinical trial that studies the effect of reduced dose radiation therapy and chemotherapy after surgery in treating patients with human papillomavirus (HPV) caused throat cancer.
- Conditions
- Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma
- Trial name
- NCT04920344
- Testing
- Transoral Surgery, External Beam Radiation Therapy, Cisplatin
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- Rutgers, The State University of New Jersey
Multiple Sclerosis
Comparing the Acute Effects of Different Exercise Approaches in Patients With Multiple Sclerosis
Multiple Sclerosis (MS) is the second most common neurological disorder in young adults after trauma. Treatments developed today can slow progression and reduce symptoms.
- Trial name
- NCT06721416
- Testing
- Traditional Aerobic Exercise, VR Based Aerobic Exercise, Conventional Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Acibadem University
Atypical Teratoid/Rhabdoid Tumor, Epithelioid Sarcoma
Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors
This phase I/II trial studies how well tiragolumab and atezolizumab works when given to children and adults with SMARCB1 or SMARCA4 deficient tumors that have either come back (relapsed) or do not respond to therapy (refractory).
- Conditions
- Atypical Teratoid/Rhabdoid Tumor, Epithelioid Sarcoma, Kidney Medullary Carcinoma, Malignant Solid Neoplasm
- Trial name
- NCT05286801
- Testing
- Atezolizumab, Biospecimen Collection, Computed Tomography
- Where
- 40 sites in United States, Australia and 1 more
- Volunteers
- 86 people
- Sponsor
- National Cancer Institute (NCI)
Stroke
Upper Limb Stroke Rehabilitation Via the VirtualRehab Platform
This study will deliver a 12-week exercise-based upper limb virtual reality, non-immersive, rehabilitation programme for stroke survivors. The aims are to:1.
- Trial name
- NCT04517812
- Testing
- Exercise-based games via the VirtualRehab platform
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Fecal Incontinence, Encopresis
Biofeedback Vs Electrical Stimulation in Treatment of Fecal Incontinence
Fecal incontinence is one of the most psychological frustrating problems. It occurs in children due to many causes. There is a wide range of non-invasive therapeutic approaches like Kegel exercise, Biofeedback, and posterior…
- Conditions
- Fecal Incontinence, Encopresis, Fecal Soiling
- Trial name
- NCT04380571
- Testing
- Biofeedback, Electrical stimulation, Traditional treatment
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Cairo University
Diabetic Neuropathies
Effect of Ankle Proprioception Training in Type 2 Diabetic Neuropathy
Diabetes mellitus is a metabolic disease described by hyperglycemia, which results from deficiencies in insulin secretion, the action of insulin on the target tissue, both.
- Trial name
- NCT05190198
- Testing
- Proprioceptive neuromuscular facilitation, conventional therapy
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Pulmonary Atelectasis, Respiratory Tract Diseases
Influence of Different Physical Therapy Resources Application After Reduction Stomach Surgery
The aim of this study will be to investigate the effects of using physical therapy resources in the postoperative morbidly obese individuals undergoing gastroplasty.
- Conditions
- Pulmonary Atelectasis, Respiratory Tract Diseases, Pathological Conditions, Signs and Symptoms
- Trial name
- NCT01872663
- Testing
- Continuous positive airway pressure, Incentive spirometry, Breath Stacking
- Where
- Brazil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
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