Clinical trials: Conventional therapy
Stroke Rehabilitation, Neurorehabilitation
Movement-activated Auricular Vagus Nerve Stimulation in Rehabilitation
Rehabilitation engineering laboratory (RELab) at the ETH Zurich is recruiting participants with a motor function deficit for studying a novel non-invasive brain stimulation method that may be a promising approach for benefiting…
- Trial name
- sVNS-rehab (NCT06623721)
- Testing
- Movement-evoked transcutaneous auricular Vagus nerve stimulation
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Olivier Lambercy
Venous Ulcers
Plasma Rich Growth Factors in Venous Ulcers
OBJECTIVES: Main objective: To evaluate the effectiveness of plasma rich in growth factors (PRGF) in the treatment of patients with venous ulcers.
- Trial name
- NCT01491438
- Testing
- PRGF+ Cleaning, debridement of the wound, application of the corresponding dressing and using of antibiotics if necessary, Cleaning, debridement of the wound, application of the corresponding dressing and using of antibiotics if necessary
- Where
- Spain
- Volunteers
- 214 people
- Sponsor
- Basque Health Service
Vulvar Lichen Sclerosus
Progesterone vs Clobetasol Propionate in Vulvar Lichen Sclerosus
This is a randomized trial comparing progesterone with conventional clobetasol propionate in patients with vulvar lichen sclerosus.
- Trial name
- NCT01126255
- Testing
- Clobetasol propionate 0.05%, Progesterone 8%
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Non-specific Low Back Pain
Acupuncture Combined With Yanqing Zhitong Ointment Acupoint Application in Chronic Non-specific Low Back Pain
Carry out a randomized controlled double-blind study, the acupuncture combined with placebo application group was compared with the acupuncture combined with Yanqing Zhitong ointment acupoint application group, 86 patients with…
- Trial name
- NCT05040243
- Testing
- Yanqing Zhitong Ointment Acupoint application
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Glioblastoma (GBM)
Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed Glioblastoma
This study aims to see if reducing blood sugar and increasing ketones (a metabolic product that comes from using fats for energy) can increase survival and enhance the the effects of standard radiation and chemotherapy treatments…
- Trial name
- NCT02046187
- Testing
- Ketogenic Diet, Radiation therapy, Temozolomide
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Breast Cancer
Chemotherapy Combined With Gene Therapy in Treating Patients Who Have Stage III or Stage IV Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Inserting the p53 gene into the tumor may increase the effectiveness of a chemotherapy drug by making tumor…
- Trial name
- NCT00044993
- Testing
- Ad5CMV-p53 gene, docetaxel, doxorubicin hydrochloride
- Where
- United States
- Sponsor
- Introgen Therapeutics
Breast Cancer
Breast-Conserving Therapy Compared With Mastectomy Followed By Radiation Therapy in Treating Women With Locally Advanced Breast Cancer Previously Treated With Chemotherapy
RATIONALE: Breast-conserving treatments such as radiation therapy or limited surgery are less invasive than mastectomy and may improve the quality of life.
- Trial name
- NCT00028704
- Testing
- conventional surgery, radiation therapy
- Where
- 13 sites in Belgium, Chile and 5 more
- Volunteers
- 26 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Sarcoma
Chemotherapy, SU5416, Radiation Therapy, and Surgery in Treating Patients With Soft Tissue Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Drugs such as SU5416 may stop the growth of cancer by stopping blood flow to the tumor.
- Trial name
- NCT00023738
- Testing
- filgrastim, dacarbazine, doxorubicin hydrochloride
- Where
- 226 sites in United States, Canada
- Sponsor
- Radiation Therapy Oncology Group
Neck Pain
Effects of Cranio-cervical Flexion on Cervical Proprioception
To determine the effects of cranio-cervical flexion training on the cervical proprioception and pain in patients with mechanical neck pain.
- Trial name
- NCT05074615
- Testing
- Cranio-Cervical Flexion Training, Conventional Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Complete Denture
Patient Satisfaction and Retention of Upper Complete Denture Base Using Rapid Prototyping Versus a Conventional One
Comparing patient satisfaction and retention of upper complete denture fabricated using two different denture base materials, the first fabricated using rapid prototyping method while the second is following conventional methods.
- Trial name
- NCT03354715
- Testing
- Rapid prototyping Denture base, Heat Cured Conventional Complete Denture
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Cairo University
Diagnosis
Mitigating Automation Bias in Physician-LLM Diagnostic Reasoning Using Behavioral Nudges
The goal of this randomized controlled trial is to evaluate whether behavioral nudges can reduce automation bias, the uncritical acceptance of automated output, in physicians using large language models (LLM) like ChatGPT-5.1 for…
- Trial name
- NCT07328815
- Testing
- Behavioral Nudge Intervention
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Lahore University of Management Sciences
Respiratory Failure
HFNC and NIV for COVID-19 Complicated by Respiratory Failure
Background: Patients with COVID-19 have a range of clinical spectrum from asymptomatic infection, mild illness, moderate infection requiring supplemental oxygen and severe infection requiring intensive care support.
- Trial name
- NCT04452708
- Testing
- HFNC
- Where
- Hong Kong
- Volunteers
- 26 people
- Sponsor
- Chinese University of Hong Kong
Burns
Comparison of High Flow vs Standard Nasal Cannula in Children With Burns Under Sedoanalgesia
The aim of this study is to investigate the positive effects of high-flow oxygen therapy on the reduction of airway adverse events and recovery time compared to conventional nasal oxygen therapy in pediatric burns treated with…
- Trial name
- NCT06663293
- Testing
- Conventional Nasal Cannula, High-flow nasal cannula, midazolam, ketamine, propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Zeliha Alicikus
Bipolar Disorder
A Study of Dayingpian Treating Bipolar Disorder
The main purpose of this cohort study is to evaluate the efficiency and safety of Dayingpian to provide evidence-based medical evidence for the subsequent drug development.
- Trial name
- NCT05247593
- Testing
- Dayingpian, conventional mood stabilizers
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Shanghai Mental Health Center
Neck Pain, Cognitive Behavior Therapy
Effects of SNAGs & CBT on Pain, Craniovertebral Angle & Disability in Non Specific Neck Pain
Non-specific neck pain is a prevalent condition causing discomfort, reduced craniovertebral angle, and disability. This randomized controlled trial will evaluate the combined effects of Sustained Natural Apophyseal Glides (SNAGs)…
- Conditions
- Neck Pain, Cognitive Behavior Therapy, Cervicalgia, Posture
- Trial name
- NCT06996015
- Testing
- Cognitive behavior therapy, Cervical Stabilization Exercises
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Urolithiasis, Nephrolithiasis
Effect of Furosemide on ESWL Outcomes for Renal and Ureteral Calculi
The minimally-invasive extracorporeal shockwave lithotripsy (ESWL) procedure is generally considered the best first-line treatment option for most adults and children with nephrolithiasis, especially when the calculi are smaller…
- Conditions
- Urolithiasis, Nephrolithiasis, Urinary Calculi, Ureterolithiasis
- Trial name
- NCT05270421
- Testing
- Furosemide 40 mg, Conventional Treatment
- Where
- Iran
- Volunteers
- 500 people
- Sponsor
- Shiraz University of Medical Sciences
Femoropopliteal Artery Occlusion, Atherosclerosis Obliterans
Lesion Preparation in Femoropopliteal Artery Occlusion Disease
Peripheral arterial disease (PAD) carries a significant global health burden, and can limit functional capacity and quality of life.
- Conditions
- Femoropopliteal Artery Occlusion, Atherosclerosis Obliterans, Lesion; Vascular, In-stent Restenosis
- Trial name
- CIVILIAN (NCT05473884)
- Testing
- lesion preparation devices, conventional balloon
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Shanghai Pudong Hospital
Treatment of Periodontitis, Guided Biofilm Therapy
Comparison of Current Subgingival Debridement Methods
Our study aimed to compare the effectiveness of current subgingival debridement methods used in the treatment of Stage 1 and Stage 2 periodontitis patients, the aesthetic condition achieved after these treatments, and the pain…
- Conditions
- Treatment of Periodontitis, Guided Biofilm Therapy, Subgingival Plaque, Subgingival Debridement
- Trial name
- NCT06835452
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Hacettepe University
Postoperative Recovery, Epidural Blockade
Enhanced Recovery After Lumber Laminectomy Using Epidural and General Anesthesia
Now, enhanced recovery after surgery (ERAS) is considered an essential goal to improve patient satisfaction, increase surgical workflow rate and facilitate performing different surgical procedures, including lumber laminectomy…
- Conditions
- Postoperative Recovery, Epidural Blockade, Endotracheal Tube, Laminectomy
- Trial name
- NCT04981158
- Testing
- (Epidural /GA using tolerable endotracheal tube (TET) group, group II, standard general anesthetic technique, control group, group I
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Zagazig University
Plantar Fascitis
Ankle Proprioceptive Neuromuscular Facilitation Technique Versus Foot Core Exercise in Patients With Plantar Fascitis
Plantar fasciitis is a common cause of heel pain due to overuse or repetitive stress on the plantar fascia. Risk factors include abnormal foot structure, obesity, and poor footwear.
- Trial name
- NCT07037290
- Testing
- Ankle proprioceptive neuromuscualar facilitation technique, Foot core exercises along with conventional physiotherapy
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Superior University
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