Clinical trials: Conventional therapy
Gastroesophageal Reflux Disease, Minimal Change Disease
Diagnostic Value of Linked Color Imaging for Minimal Change Esophagitis in Nonerosive Reflux Esophagitis and GERD
Linked color imaging(LCI),a new system for endoscopy modality,creates clear and bright endoscopic images by using short-wavelength narrow-band laser light combined with white laser light on the basis of magnifying blue laser…
- Conditions
- Gastroesophageal Reflux Disease, Minimal Change Disease, Non-Reflux Esophagitis
- Trial name
- NCT03068572
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Liver Transplantation
Research on Using Small-for-size Grafts for Auxiliary Liver Transplantation in the Treatment of Portal Hypertension
The objective of this observational study is to compare the safety profile of auxiliary liver transplantation using small-for-size grafts with that of conventional liver transplantation and to evaluate the efficacy of this…
- Trial name
- NCT07247877
- Volunteers
- 396 people
- Sponsor
- Zhi-Jun Zhu
Growth Hormone, EndoSeal MTA
Evaluation of the Efficacy of Growth Hormone, EndoSeal MTA Sealer, and Their Combination on Healing of Periapical Pathosis
This study aimed to evaluate the effect of growth hormone, EndoSeal MTA sealer, and their combination on Healing of Periapical Pathosis.
- Conditions
- Growth Hormone, EndoSeal MTA, Periapical Pathosis
- Trial name
- NCT06433375
- Testing
- Growth hormone application, Root canal treatment
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Respiratory Failure
Effects of Treatment With High Flow Nasal Cannulas on Respiratory Pattern and Work of Breathing Among Healthy Subjects
This study evaluates the work of breathing among healthy subjects under various conditions of treatment with high flow nasal cannulas. Ten subjects will be included.
- Trial name
- HDWOBSS (NCT02495675)
- Testing
- High flow nasal cannulas, Conventional flow via nasal prongs
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Laval University
Cerebral Palsy Spastic Diplegia
Comparison of the Effects of Vojta and Bobath Treatment on Gait and Balance in Diplegic Cerebral Palsy
This study aims compare the effects of Vojta verses Bobath therapy on gait in children with diplegic cerebral palsy and to compare the effects of Vojta versus Bobath therapy on balance in children with diplegic cerebral palsy.
- Trial name
- NCT06757101
- Testing
- Vojta Therapy, Bobath Therapy, Combined Vojta and Bobath Therapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Riphah International University
Multiple Sclerosis
Comparison of 1.5T vs. 3T Protocols After Treatment With Glatiramer Acetate (GA)
This study will: Explore whether GA decreases inflammation more on the 3T optimized protocol when compared to the 1.5T standard protocol.
- Trial name
- NCT00937157
- Testing
- Copaxone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University at Buffalo
Bronchoscopy
Effects of Different Ventilatory Strategy During Bronchoscopy
The execution of diagnostic-therapeutic investigations by bronchial endoscopy can expose the patient to hypoxemia. For this reason, oxygen therapy is administered at low or high flows during the course of bronchoscopic…
- Trial name
- NCT05956301
- Testing
- Conventional Oxygen Therapy, High-flow nasal oxygen, Supraglottic jet oxygenation and ventilation
- Volunteers
- 150 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Multiple Sclerosis
Effect of Sensory Integration Therapy on Gait Variability and Quality Of Life in Patients With Multiple Sclerosis
This study aims to evaluate the impact of sensory integration therapy on individuals with multiple sclerosis (MS) by examining its effects on gait variability and overall quality of life.
- Trial name
- NCT07390201
- Testing
- Conventional physical therapy program, Sensory integration therapy
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Cairo University
Gallbladder Carcinoma
Target Therapy With GEMOX in Recectable Gallbladder Carcinoma Patients Monitored by ctDNA
The purpose of this study is to evaluate the feasibility, efficacy and safety of target therapy according to genomic and proteomic profiling combined with GEMOX in recectable gallbladder carcinoma patients monitored by ctDNA.
- Trial name
- NCT04183712
- Testing
- gemcitabine and oxaliplatin., Afatinib
- Where
- 2 sites in China
- Volunteers
- 102 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Multiple Sclerosis
Blood Flow Restriction for Upper Limb Rehabilitation in People With Multiple Sclerosis. A Randomized Controlled Trial (BFRT-EM)
Although the Blood Flow Restriction Training (BFRT) system has attracted the attention of health professionals, research on this tool in people with neurological pathology, particularly multiple sclerosis (MS), is very limited.
- Trial name
- BFRT-EM (NCT06795230)
- Testing
- Muscle strengthening (BFRT), Conventional physical therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Rey Juan Carlos
TMJ Disc Disorder, Ultrasound Therapy; Complications
Ultrasound-Guided Vs Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. a Randomized Clinical Trial
Ultrasound Guided Versus Non-Guided Prolotherapy for Treatment of Internal Derangement of Temporomandibular joint. Rationale for conducting the research: The most critical cause for guided prolotherapy is to specify the accurate…
- Conditions
- TMJ Disc Disorder, Ultrasound Therapy; Complications, TMJ, Prolotherapy
- Trial name
- NCT05627830
- Testing
- Prolotherapy
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Long-term Oral Anticoagulant Therapy
Self-management of Anticoagulation Treatment
The aim of the study was to compare self-management of anticoagulant treatment with conventional anticoagulant treatment in Norway.
- Trial name
- NCT02371772
- Testing
- Training
- Volunteers
- 23 people
- Sponsor
- Una Ørvim Sølvik
Hypertension
Effect of a Pharmacist-led Multifaceted Intervention on Treatment Outcomes in Hypertensive Patients
The objective of this cluster randomized controlled trial is to evaluate the effectiveness of a pharmacist-led multifaceted intensive blood pressure intervention on poorly controlled hypertensive patients in phase 1 (1 month, 3…
- Trial name
- NCT06558877
- Testing
- pharmacist-led multifaceted intervention, conventional health education
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Xijing Hospital
D012893, Sleep Disorder
Prevalence of Sleep Disturbances in Elderly People Hospitalized in Medicine, Psychiatry and Rehabilitation Departments: TOPASE Prospective Study, RIPH 3
Objectives and evaluation criteria: The main objective of this study is to evaluate changes in sleep quality in patients aged 60 and over since their admission to a medical, psychiatric or medical and rehabilitation ward in one…
- Trial name
- TOPASE (NCT06659575)
- Where
- 10 sites in France
- Volunteers
- 104 people
- Sponsor
- University Hospital, Angers
Intracranial Aneurysm
Therapeutic Effect of Blood Flow Reconstruction in IVADA
IVADA (Intracranial vertebral artery dissecting aneurysms）is one of the causes of subarachnoid hemorrhage or posterior circulation ischemia with high mortality and disability.
- Trial name
- NCT06134557
- Testing
- conventional stents
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Qilu Hospital of Shandong University
Malaligned Teeth, Crowding of Teeth
Effect of Different Adhesive Systems on White Spot Lesions During Fixed Orthodontic Treatment
The primary goal of this study is to compare the number of white spot lesions during fixed appliance therapy between self-etch and one-step bonding systems.
- Trial name
- NCT07753512
- Testing
- Self-etch adhesive, One-Step Adhesive, Conventional Bonding Technique
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Relapsed Pediatric Solid Tumor, Refractory Pediatric Solid Tumor
Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy
The purpose of this study is to evaluate the efficacy and feasibility of combination chemotherapy with target agents according to the result of targeted deep sequencing in pediatric patients with relapsed/refractory solid tumor…
- Conditions
- Relapsed Pediatric Solid Tumor, Refractory Pediatric Solid Tumor, Relapsed Pediatric AML, Refractory Pediatric AML
- Trial name
- NCT02638428
- Testing
- CancerSCAN™, Ifosfamide, Carboplatin
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Psoriasis
Swiss Dermatology Network of Targeted Therapies (SDNTT)
The purpose of this study is to evaluate the long-term course of patients with psoriasis and psoriatic-arthritis in systemic treatments such as, methotrexate, cyclosporin A, fumaric acids, acitretin, systemic PUVA, etanercept…
- Trial name
- SDNTT (NCT01706692)
- Testing
- Adalimumab, Etanercept, Infliximab
- Where
- 6 sites in Switzerland
- Volunteers
- 1,121 people
- Sponsor
- Swiss Dermatology Network for Targeted Therapies
Breast Cancer
An Innovative Smartphone Application for Adverse Event Management During Breast Cancer Adjuvant Chemotherapy
The aim of this study is to evaluate benefits of the app in breast cancer patients receiving the docetaxel, doxorubicin, and cyclophosphamide (TAC) chemotherapy.
- Trial name
- NCT05258461
- Testing
- use of a smartphone app for adverse event management, conventional adverse event management
- Volunteers
- 108 people
- Sponsor
- Peking Union Medical College Hospital
Colorectal Neoplasm, Effects of Radiation Therapy
Randomized Trial of Primary Surgery Followed Selective Radiochemotherapy for Rectal Cancer With MRI Negative CRM
The purpose of this study is to determine whether primary radiotherapy can be omitted for the locally advanced rectal cancer with Magnetic Resonance Imaging (MRI) negative circumferential margin.
- Conditions
- Colorectal Neoplasm, Effects of Radiation Therapy, Effects of Chemotherapy, Surgery
- Trial name
- PSSR (NCT02121405)
- Testing
- Rectectomy, Radiotherapy, Capecitabine
- Where
- 7 sites in China
- Volunteers
- 350 people
- Sponsor
- Zhejiang University
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