Clinical trials: Conventional therapy, completed
Sarcoma
Radiation Therapy With or Without SU5416 in Treating Patients With Soft Tissue Sarcoma
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs such as SU5416 may stop the growth of cancer by stopping blood flow to the tumor.
- Trial name
- NCT00023725
- Testing
- semaxanib, conventional surgery, radiation therapy
- Where
- 226 sites in United States, Canada
- Sponsor
- Radiation Therapy Oncology Group
Prostate Cancer, Sexual Dysfunction
Intensity-Modulated Radiation Therapy With or Without Decreased Radiation Dose to Erectile Tissue in Treating Patients With Stage II Prostate Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Intensity-modulated radiation therapy (radiation directed at the tumor more precisely than in standard radiation therapy) may reduce damage to healthy…
- Conditions
- Prostate Cancer, Sexual Dysfunction, Sexuality and Reproductive Issues
- Trial name
- NCT00084552
- Testing
- radiation therapy
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Fox Chase Cancer Center
Coronary Artery Disease
OPTImal Management of Antithrombotic Agents: OPTIMA-2 Trial
High on-treatment platelet reactivity (HOPR) is associated with increased risk of cardiovascular events in patients undergoing percutaneous coronary intervention (PCI).
- Trial name
- OPTIMA-2 (NCT01955200)
- Testing
- Clopidogrel, Cilostazol, Ticagrelor
- Where
- China
- Volunteers
- 1,724 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Mitral Regurgitation
Early Surgery Versus Conventional Treatment for Asymptomatic Severe Mitral Regurgitation
The timing of surgical intervention in asymptomatic patients with severe degenerative mitral regurgitation (MR) remains controversial.
- Trial name
- NCT01703806
- Testing
- Early Surgery, Watchful Observation
- Where
- 2 sites in South Korea
- Volunteers
- 1,063 people
- Sponsor
- Asan Medical Center
Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia
Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients.
To evaluate the safety, efficacy and pharmacokinetics of nilotinib over time in the Ph+ chronic myelogenous leukemia (CML) in pediatric patients (from 1 to <18 years).
- Trial name
- DIALOG (NCT01844765)
- Testing
- nilotinib
- Where
- 36 sites in United States, France and 11 more
- Volunteers
- 59 people
- Sponsor
- Novartis Pharmaceuticals
Stage I Kidney Wilms Tumor, Stage II Kidney Wilms Tumor
Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' Tumor
This phase III trial is studying vincristine, dactinomycin, and doxorubicin with or without radiation therapy or observation only to see how well they work in treating patients undergoing surgery for newly diagnosed stage I…
- Conditions
- Stage I Kidney Wilms Tumor, Stage II Kidney Wilms Tumor, Stage III Kidney Wilms Tumor
- Trial name
- NCT00352534
- Testing
- 3-Dimensional Conformal Radiation Therapy, Biospecimen Collection, Chest Radiography
- Where
- 240 sites in United States, Australia and 5 more
- Volunteers
- 808 people
- Sponsor
- Children's Oncology Group
Primary Dysmenorrhea
Primary Dysmenorrhea and Mobilization.
72 women diagnosed with primary dysmenorrhea were included in the study and divided into four groups. the first group received treatment with a mobilization approach, the second group received motor imagery-focused exercises and…
- Trial name
- NCT07314021
- Testing
- FEMOB, MOPEXE, Conventional Treatment group
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Medipol University
Percutaneous Nephrolithotomy, Renal Stones
Effectiveness of US-Guided PCNL Different Positions in Renal Stones Treatment
The aim of this study is to compare the effectiveness of Ultrasound-Guided Percutaneous nephrolithotomyin different positions supine, prone positions and flank suspend supine position in renal stones treatment.
- Conditions
- Percutaneous Nephrolithotomy, Renal Stones, Ultrasound Therapy; Complications
- Trial name
- NCT05855057
- Testing
- Flank suspended supine position percutaneous nephrolithotomy, Supine percutaneous nephrolithotomy group, Prone percutaneous nephrolithotomy group
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Benha University
Pleomorphic Rhabdomyosarcoma, Stage IIB Adult Soft Tissue Sarcoma AJCC v7
Sorafenib Tosylate, Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With High-Risk Stage IIB-IV Soft Tissue Sarcoma
This phase II trial studies how well sorafenib tosylate, combination chemotherapy, radiation therapy, and surgery work in treating patients with high-risk stage IIB-IV soft tissue sarcoma.
- Conditions
- Pleomorphic Rhabdomyosarcoma, Stage IIB Adult Soft Tissue Sarcoma AJCC v7, Stage III Adult Soft Tissue Sarcoma AJCC v7, Stage IV Adult Soft Tissue Sarcoma AJCC v7
- Trial name
- NCT02050919
- Testing
- Epirubicin Hydrochloride, External Beam Radiation Therapy, Ifosfamide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- OHSU Knight Cancer Institute
Development Coordination Disorder
Active Video Games in Children With DCD
Developmental Coordination Disorder (DCD) is a condition that affects a child's ability to perform coordinated motor activities and may also impact visual perception and motor planning skills.
- Trial name
- NCT07631832
- Testing
- Active Video Game Training, Conventional Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- ZEYNEP KOLİT
Malocclusion, Orthodontics
Occlusal Outcomes by OGS After a Finishing Protocol
Evaluation of the effects of the implementation of a new finishing protocol in orthodontics patients
- Trial name
- NCT03714087
- Testing
- T1 before aligner, T2 after the aligner, Historic control group
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Caries
Effectiveness of an ICCMS™ Caries Management Program.
The aim of this study is to compare in schoolchildren the effectiveness of an updated caries management program based on the current caries paradigm with the ICCMS™ system (International Caries Classification and Management…
- Trial name
- NCT04676230
- Testing
- Experimental group, Control group
- Where
- Colombia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
Chronic Stroke
The Application of Sling Exercise Training in People With Chronic Stroke
The purpose of this single-blinded, randomized controlled study aims to investigate the effects of sling exercise training (SET) for core muscle on gait performance in people with chronic stroke.
- Trial name
- NCT05352009
- Testing
- Sling exercise training, Conventional balance training
- Where
- Taiwan
- Volunteers
- 19 people
- Sponsor
- National Yang Ming Chiao Tung University
Malignant Mesothelioma
Combination Chemotherapy With or Without Surgery & Chemoradiotherapy in Patients With Malignant Pleural Mesothelioma
RATIONALE: Drugs used in chemotherapy, such as methotrexate, vinorelbine, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00354393
- Testing
- Cisplatin, Methotrexate, Vinorelbine ditartrate
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The Cleveland Clinic
Type 1 Diabetes
Closing the Loop in Adolescents During Non-compliance Behaviours
The ultimate goal of the investigators ongoing research is the development of a closed-loop system for insulin delivery, which can help people with type 1 diabetes (T1D) attain a tight glucose control avoiding the risk of…
- Trial name
- NCT01629277
- Testing
- Closed-loop, standard insulin pump
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Cambridge
Alcoholic Hepatitis
Utility of the Use of N-acetylcysteine Associated With Conventional Treatment in Patients With Severe Acute Alcoholic Hepatitis (Maddrey> 32)
This study is designed to evaluate the hypothesis that patients with severe acute alcoholic hepatitis have lower morbi-mortality if the patients receive treatment with corticosteroids + NAC, compared to patients that only receive…
- Trial name
- NCT05294744
- Testing
- N-acetylcysteine
- Where
- Spain
- Volunteers
- 390 people
- Sponsor
- Bioaraba Health Research Institute
Hemiplegia, Muscle Spasticity
Tele-physiotherapy on Post-stroke Hemiplegia Patients
The present preliminary randomized trial will be performed to compare the effectiveness of telephyisiotherapy plus physical exercises versus other conventional techniques (electromyographic biofeedback or conventional…
- Trial name
- NCT06048432
- Testing
- Conventional Physiotherapy + telephysiotherapty
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Hemiplegia, Spastic
Use of Rhythmic Auditory Cueing During Bilateral Training of the Upper Extremities in Stroke Patients
The purpose of the study is to determine the effect of rhythmic auditory cueing with bilateral arm training on upper limb functions in stroke patients.
- Trial name
- NCT04939493
- Testing
- Rhythmic Auditory Cueing, Bilateral arm training, Conventional physical therapy program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Pulmonary Hypertension
Influence of Respiratory and Exercise Therapy on Oxygen Uptake, Quality of Life and Right Ventricular Function in Severe Pulmonary Hypertension
Aim of this study is to investigate whether and to what extent a cautious respiratory and exercise therapy can complement medical treatment and change the condition, oxygen uptake, quality of life, the pulmonary vascular…
- Trial name
- NCT01394367
- Testing
- respiratory and exercise therapy
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Heidelberg University
Hemiplegic Cerebral Palsy
Effects of Classic and Modified CIMT on Quality of Life of Children With Hemiplegic CP
The purpose of this research is to see the effect of classic constraint-induced movement therapy and its modified form on quality of life of children with hemiplegic cerebral palsy.
- Trial name
- CIMT (NCT06021899)
- Testing
- modified constraint induced movement therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Health Education Research Foundation (HERF)
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