Clinical trials: Conventional therapy
Caries,Dental
Comparison of the Treatment Outcomes of the Conventional Stainless Steel Crown Restorations and the Hall Technique in the Treatment of Carious Primary Molars
Stainless steel crowns have shown high success in restoring carious primary molars over a longer period of time than conventional restorations.
- Trial name
- NCT06597669
- Testing
- Placement of stainless steel crowns on primary molars
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hue University of Medicine and Pharmacy
Bronchiolitis, Respiratory Failure (Pediatric Patients)
Nurse-led High-flow Nasal Cannula Weaning Protocol in Pediatric Intensive Care Unit
Bronchiolitis is a leading cause of pediatric hospital admissions. Despite its limited clinical benefits, the use of HFNC in children with bronchiolitis is increasing.
- Conditions
- Bronchiolitis, Respiratory Failure (Pediatric Patients), High Flow Nasal Cannula
- Trial name
- NCT06621641
- Testing
- The new HFNC weaning protocol
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Stroke, Splints
Spiral Strapping for Improving Upper Limb Functions
Upper limb recovery after stroke is unacceptably poor with almost half of stroke survivors likely to regain some functional use.
- Conditions
- Stroke, Splints, Physical Disability
- Trial name
- NCT05725941
- Testing
- TogRite stretch Strapping, Traditional upper limb functional exercise training
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Umm Al-Qura University
Breast Cancer
Intravenous Ascorbic Acid Supplementation in Neoadjuvant Chemotherapy for Breast Cancer
Forty years ago clinical studies conducted by Ewan Cameron and Linus Pauling suggested that intravenous (IV) and oral ascorbic acid (AA) may diminish symptoms and could improve survival in terminal cancer patients.
- Trial name
- NCT03175341
- Testing
- Ascorbic Acid
- Where
- Romania
- Volunteers
- 30 people
- Sponsor
- Academic Emergency County Hospital Sibiu
Nasopharyngeal Cancer, Epstein-Barr Virus Infections
Efficacy of Recombinant Epstein-Barr Virus (EBV) Vaccine in Patients With Nasopharyngeal Cancer Who Had Residual EBV DNA Load After Conventional Therapy
The purpose of this study is to evaluate the efficacy (clinical benefit rate) of MVA EBNA1/LMP2 vaccine in patients with persistent, recurrent or metastatic nasopharyngeal carcinoma, and its impact on disease progression.
- Trial name
- NCT01094405
- Testing
- Recombinant Epstein-Barr Virus (EBV) Vaccine
- Where
- Hong Kong
- Volunteers
- 25 people
- Sponsor
- Chinese University of Hong Kong
Breast Cancer Metastatic, Hormone Receptor Positive Malignant Neoplasm of Breast
Rogaratinib, Palbociclib y Fulvestrant in Patients With Breast Cancer.
This study is an open, multicenter, prospective phase I dose escalation clinical trial followed by an expansion cohort. The aim of this study is to asses the Recommended Phase 2 Dose (R2PD) and the safety profile, among other…
- Trial name
- ROGABREAST (NCT04483505)
- Testing
- Combination, Rogaratinib + palbociclib + fulvestrant
- Where
- 8 sites in Spain
- Volunteers
- 9 people
- Sponsor
- Fundacion CRIS de Investigación para Vencer el Cáncer
Colorectal Cancer (CRC)
Neoantigen-based Peptide Vaccine and Conventional Third-line Therapy for CRC Progressed After Second-line Treatment
In this study, the investigators provide a combined treatment of personalized tumor neoantigen-based peptide vaccine and conventional third-line therapy to patients with colorectal cancer (CRC) progressed after second-line…
- Trial name
- NCT06751966
- Testing
- Combination Product: Conventional third-line therapy, Neoantigen-based peptide vaccine
- Where
- 2 sites in China
- Volunteers
- 10 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Bronchiectasis with Acute Exacerbation
Value of Bronchoalveolar Lavage with Acetylcysteine in the Treatment of Bronchiectasis.
Bronchiectasis is a clinical syndrome characterised by chronic cough, profuse sputum and/or intermittent haemoptysis, with or without shortness of breath and respiratory failure of varying severity, and abnormal thickening and…
- Trial name
- NCT06726356
- Testing
- Bronchoalveolar Lavage
- Where
- China
- Volunteers
- 180 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Low Back Pain, Radicular Syndrome
Comparison of High-Intensity and Conventional Physical Therapy in Musculoskeletal Disorders
This pilot randomized controlled trial aims to compare the clinical effectiveness of advanced high-intensity physical therapy modalities with conventional physical therapy in patients suffering from musculoskeletal disorders.
- Conditions
- Low Back Pain, Radicular Syndrome, Sacroiliac Joint Dysfunction, Shoulder Impingement Syndrome
- Trial name
- NCT07903142
- Testing
- Repetitive Peripheral Magnetic Stimulation (rPMS), High-Intensity Laser Therapy (HIL), Extracorporeal Shockwave Therapy (ESWT)
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- BTL Industries Ltd.
Diabetes Mellitus Type 2, Diastolic Dysfunction
Effect of Liraglutide on Diastolic Dysfunction on Cardiac MRI in Type 2 Diabetes Patients
The purpose of this study is to determine whether liraglutide a GLP-1 analogue are effective in the treatment of diastolic dysfunction in type 2 diabetes patients analyzed by cardiac MRI.
- Conditions
- Diabetes Mellitus Type 2, Diastolic Dysfunction, Cardiac MRI, Myocardial Perfusion
- Trial name
- NCT02655770
- Testing
- Liraglutide
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Stroke
The Effect of Action Observation Therapy Including Unimanual and Bimanual Activities in Chronic Stroke
Functional impairments in the upper extremities following a stroke significantly restrict individuals' activities of daily living and overall quality of life; in this context, Action Observation Training (AOT) has emerged in…
- Trial name
- NCT07631169
- Testing
- Action Observation Therapy(unimanuel activities), Action Observation Therapy(bimanuel activities), conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Karabuk University
Stress Urinary Incontinence
Autologous Rectus Sheath Fascia Versus Midurethral Transobturator Tension Free Vaginal
a hybrid sling formed of a central part of autologus rectus sheath (2×6 cm) and two arms of polypropylene mesh (2×10cm) versus transobturator tension free vaginal tape(TVT-O)
- Trial name
- NCT03473041
- Testing
- Hybrid sling, TVT-O
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- sarah mohamed hassan
Cerebral Palsy
Effects of Upperlimb Sensorimotor Training in Hemiplegic Cerebral Palsy
The study aims to determine the effects of upper limb sensorimotor training as compared to task oriented raining in subjects with cerebral palsy.
- Trial name
- NCT06011616
- Testing
- Sensory training, Motor training, Conventional exercises
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Cervical Cancer, Neoplasm Recurrence, Local
Iparomlimab and Tuvonralimab With Chemoradiation for the Treatment of Locally Recurrent and Oligometastatic Cervical Cancer
The goal of this clinical trial is to evaluation the efficacy and safety of iparomlimab and tuvonralimab, paclitaxel + cisplatin/carboplatin combined with radiotherapy of locally recurrent and oligometastatic cervical cancer.The…
- Conditions
- Cervical Cancer, Neoplasm Recurrence, Local, Oligometastatic
- Trial name
- NCT06942416
- Testing
- Paclitaxel and Cisplatin/ Carboplatin, Iparomlimab and Tuvonralimab, Radiotherapy
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shandong Cancer Hospital and Institute
Low Back Pain, Muscle Strength
Back Squat Exercise Treatment for Low Back Pain: Clinical Trial
Summary: Low back pain is the leading cause of deficiency and loss of productivity worldwide. No evidence of any particular exercise was more effective than another for treating nonspecific low back pain.
- Conditions
- Low Back Pain, Muscle Strength, Visceral Obesity, Spine Disease
- Trial name
- NCT04691258
- Testing
- Experimental: Complete Group, Active Comparator: Restricted Group
- Where
- 3 sites in Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal de Goias
Supervision of Pregnancy Resulting From In-vitro Fertilization
Transcutaneous Electrical Acupoint Stimulation to Improve Pregnancy Rates for Women Undergoing in Vitro Fertilization
The objective of this study is to investigate the effect of transcutaneous electrical acupoint stimulation on pregnancy rates in women undergoing in vitro fertilization.
- Trial name
- NCT01608048
- Testing
- transcutaneous electrical acupoint stimulation (TEAS);EA
- Where
- China
- Volunteers
- 384 people
- Sponsor
- Huazhong University of Science and Technology
Asthma, Care Management, Patient
Digital Prevention of Asthma
Asthma self-management is dependent on support and education. To facilitate self-management have we developed and CE-mark a novel digital self-management system called Asthmatuner (Medituner AB, Sweden).The primary aim of this…
- Trial name
- AsthmaTuner (NCT04132778)
- Testing
- AsthmaTuner
- Where
- 2 sites in Sweden
- Volunteers
- 331 people
- Sponsor
- Karolinska Institutet
Periodontitis, Periodontitis Stage II
Spirulina Gel in the Treatment of Periodontitis
This randomized clinical trial aims to evaluate the clinical and immunological effects of locally delivered Spirulina gel as an adjunct to scaling and root planing (SRP) in patients with Stage II, Grade B periodontitis.
- Trial name
- non (NCT07893587)
- Testing
- spirulina gel exracted by 1.5% calcium chloride (CaCl2) aqueous solution., conventional scaling and root planing
- Volunteers
- 20 people
- Sponsor
- Misr University for Science and Technology
Malocclusion, Orthodontics
Occlusal Outcomes by OGS After a Finishing Protocol
Evaluation of the effects of the implementation of a new finishing protocol in orthodontics patients
- Trial name
- NCT03714087
- Testing
- T1 before aligner, T2 after the aligner, Historic control group
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Hypertension
Effects of Telemonitoring and Telemedicine Service for Hypertensive Care
This is a multi-centered, randomized, parallel group, interventional \& open label clinical trial accessing efficacy of intervention effect by smart care system over existing treatment group for lowering blood pressure of…
- Trial name
- Smart-HTN (NCT01335984)
- Testing
- Telemonitoring, Telemonitoring & Telemedicine, control group
- Where
- 3 sites in South Korea
- Volunteers
- 440 people
- Sponsor
- Chang Hee, Lee
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