Clinical trials: Conventional therapy
Dual Energy CT (DECT), Prostate Cancer
Applications of Dual Energy CT in Patients With Osseous Metastases From Castrate-resistant Prostate Cancer
The purpose of this study is to establish a more accurate and precise way to image (take pictures of) metastatic bone disease in patients with prostate cancer for staging and monitoring response to therapy.
- Trial name
- NCT03111914
- Testing
- Dual Energy Computed Tomography
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duke University
Smoking
Nicotine Pharmacokinetic Profile and Safety of the Tobacco Heating System 2.2 Menthol (THS 2.2 Menthol).
The primary objective of this clinical study is to evaluate the pharmacokinetic (PK) profile (rate and amount of nicotine absorbed) following a single use of the THS 2.2 Menthol (mTHS), a candidate Modified Risk Tobacco Product…
- Trial name
- NCT01967706
- Testing
- mTHS, mCC, NRT
- Where
- Japan
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Stroke, Upper Extremity Paresis
Functional Recovery in Stroke Patients With Task-Specific Robot-Aided Arm Therapy
The goal of this study is to determine whether task-oriented, robot-aided therapy is more effective than conventional physical and occupational therapy at promoting functional recovery of the affected arm in chronic hemiparetic…
- Trial name
- NCT00719433
- Testing
- robot therapy (ARMin), conventional therapy
- Where
- Switzerland
- Volunteers
- 76 people
- Sponsor
- University of Zurich
Brain Diseases, Brain Neoplasms
A Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain Metastases
This Phase I clinical trial is studying the side effects and best dose of ABT-888 when given together with Whole Brain Radiation Therapy (WBRT) in treating patients with brain metastases.
- Conditions
- Brain Diseases, Brain Neoplasms, Central Nervous System Diseases, Neoplasm Metastasis
- Trial name
- NCT00649207
- Testing
- ABT-888, Whole Brain Radiation Therapy
- Where
- 9 sites in United States, Canada and 1 more
- Volunteers
- 80 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer
Efficacy of Auricular Acupuncture Therapy in the Prevention of CIPN in Breast Cancer
Evaluate the Efficacy of Auricular Acupuncture Therapy via the Seirin Pyonex Needles in the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer
- Trial name
- NCT07092111
- Testing
- Auricular acupuncture treatment
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Stroke Sequelae
Action Observation Training for Upper Limb Recovery in Patients With Stroke
Background: Due to the complexity of the interventions in recovering the upper limb, at the moment there is a lack of evidence about the efficacy of rehabilitative interventions.
- Trial name
- NCT04604171
- Testing
- Action Observation Training, Task Oriented Training, Conventional Treatment
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Azienda USL Toscana Sud Est
Malocclusion, Angle Class I, Malocclusion; Displaced or Missing Teeth
Comparison Between Clear Aligners and Traditional Fixed Appliances in the Treatment of Four-premolar-extraction Cases
Patients who have severe crowding that require four premolars extraction will be treated in this study. The efficacy of the clear aligners and vestibular fixed appliances will be assessed.
- Conditions
- Malocclusion, Angle Class I, Malocclusion; Displaced or Missing Teeth, Crowding
- Trial name
- NCT03645356
- Testing
- Fixed Appliances, Clear Aligners
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Pneumocystis Pneumonia, Pneumocystis Jirovecii Infection
CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis Pneumonia
To assess the efficacy of administrating daily caspofungin aerosols versus placebo for seven days, in adjunction of conventional systemic antifungal therapy during curative treatment of Pneumocystis pneumonia, on the clinical…
- Conditions
- Pneumocystis Pneumonia, Pneumocystis Jirovecii Infection, Pneumocystis Infections
- Trial name
- CaspoNEB (NCT06892951)
- Testing
- Caspofungin Acetate 50 MG, Physiologic saline
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Aphasia Non Fluent, Stroke
Sensory-Motor Integration for Speech Rehabilitation in Patients With Post-stroke Aphasia
SEMO is a multidisciplinary project (language sciences, cognitive psychology and neuropsychology, physical medicine and rehabilitation, neurology, speech-language pathology, functional neuroimaging and engineering sciences) that…
- Trial name
- SEMO (NCT04433351)
- Testing
- Enriched rehabilitation, Simple rehabilitation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Grenoble
Cerebral Palsy
Effects of Stationary Cycling and Progressive Functional Training in Cerebral Palsy Children
Cerebral palsy is not a progressive disease but movement problem and musculoskeletal disorders in cerebral palsy change with time.
- Trial name
- NCT06198153
- Testing
- Stationary Cycling, Progressive Functional Training
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Head and Neck Cancer, Radiotherapy, Conformal (IMRT)
SGRT in Head and Neck Cancer Radiotherapy
This study is a prospective, randomized, open-label, single-center exploratory trial. A total of 40 newly diagnosed, untreated head and neck cancer patients （stage I-IVa, AJCC 8th edition） will be enrolled and randomly assigned…
- Trial name
- NCT07726407
- Testing
- SGRT-guided radiotherapy with open thermoplastic mask immobilization, Closed head-neck-shoulder thermoplastic mask with laser alignment
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Metastatic, Cerebral Primitive Neuroectodermal Tumors
Treatment of High-Risk Cerebral Primitive Neuroectodermal Tumors in Children Aged Over 5 Years
Primary objective : To increase the 3 year progression-free survival from 40% to 60%. Patients included : metastatic, cerebral primitive neuroectodermal tumors in children aged over 5 years.
- Trial name
- NCT00936156
- Testing
- Chemotherapy (carboplatin, etoposide, thiotepa)
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Post Operative Pain, Post Operative Anxiety
The Effect of Virtual Reality on Postoperative Pain and Anxiety in Cardiac Surgery.
The objective of this study is to investigate the effect of VR on post-operative pain and anxiety management in cardiac surgery patients undergoing a coronary artery bypass grafting (CABG) procedure.
- Conditions
- Post Operative Pain, Post Operative Anxiety, Heart Surgery, Coronary Artery Bypass Grafting
- Trial name
- VRECOVERY (NCT06001502)
- Testing
- Virtual Reality distraction therapy
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Venous Ulcer
TAPIRS Technique Plus Adjustable Compression System in Treatment of Venous Leg Ulcers
The aim of this study is to determine the percentage of healing of active venous ulcers following Terminal Axial Perforator Interruption Reflux Source (tapirs technique) and adjustable compression system versus a control group…
- Trial name
- TAPIRS (NCT02798445)
- Testing
- TAPIRS, CONTROL
- Volunteers
- 26 people
- Sponsor
- Hospital Occidente de Kennedy
Alzheimer Disease, Occupational Therapy
Quality-of-Life-and-Cognitive-Oriented Rehabilitation Through the NeuronUP in Alzheimer's Disease
Introduction: New technologies are a support in the rehabilitation of users. The therapeutic approach to cognitive rehabilitation encompasses a variety of techniques, among which traditional occupational therapy stands out.
- Conditions
- Alzheimer Disease, Occupational Therapy, Quality of Life, Cognitive Impairment
- Trial name
- NCT06499272
- Testing
- Conventional occupational therapy sessions + NeuronUP, Conventional occupational therapy sessions
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Universidad Rey Juan Carlos
Stroke, Proprioceptive Disorders
Combined Effects of PNF and Electrical Muscle Stimulation on Spasticity and Hand Function in Stroke Patients.
To determine the combined effects of proprioceptive neuromuscular facilitation and electrical muscle stimulation on spasticity and hand function in stroke patients.
- Conditions
- Stroke, Proprioceptive Disorders, Balance; Distorted
- Trial name
- NCT05916872
- Testing
- experimental group, control group
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Acute Cholecystitis, Gangrenous Cholecystitis
Enhanced Recovery in Laparoscopic Cholecystectomy
The study assesses the impact of the modified enhanced recovery protocol on the results of surgical treatment of patients with acute cholecystitis.
- Trial name
- ERLAC (NCT03754751)
- Testing
- Laparoscopic cholecystectomy with the implementation of modified ERAS program, Laparoscopic cholecystectomy with standard perioperative treatment
- Where
- Russia
- Volunteers
- 189 people
- Sponsor
- Pirogov Russian National Research Medical University
Sudden Sensorineural Hearing Loss, Tinnitus
The Development of Tinnitus in Patients With SSNHL: Insights From fMRI and Metabolomics
The goal of this clinical trial is to investigate the factors and mechanisms underlying tinnitus generation and chronification in patients with sudden sensorineural hearing loss (SSNHL) .
- Trial name
- NCT06355102
- Testing
- Conventional treatment and care
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Hemiplegia
Effects of Auditory and Visual Cueing on Sensorimotor Recovery and Gait in Hemiplegia
Stroke is also known as a brain attack, happens when a blood vessel in the brain breaks or when something stops the flow of blood to a specific area of the brain. Parts of the brain undergo damage or die in either case.
- Trial name
- NCT06059781
- Testing
- Rhtyhmical auditory stimulation and Visual cues (Experimental group), Rhtyhmical auditory stimulation (Control group)
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Breast Cancer
Surgery With or Without Lymph Node Removal in Treating Older Women With Stage I or Stage IIA Breast Cancer
RATIONALE: Removing axillary lymph nodes may be effective in stopping the spread of breast cancer cells. It is not yet known if surgery to remove breast cancer is more effective with or without lymph node removal.
- Trial name
- 10-93 (NCT00002528)
- Testing
- tamoxifen citrate, conventional surgery, radiation therapy
- Where
- 21 sites in Australia, Hungary and 7 more
- Volunteers
- 473 people
- Sponsor
- ETOP IBCSG Partners Foundation
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.