Clinical trials: Conventional therapy
Severe Acute Pancreatitis, Intra-abdominal Hypertension
Efficacy and Safety of Da-Cheng-Qi Decoction in Severe Acute Pancreatitis
This single-center prospective randomized controlled trial evaluated Da-Cheng-Qi Decoction (DCQD) as the acute-stage intervention of an integrated traditional Chinese and Western medicine whole-stage treatment protocol for severe…
- Trial name
- NCT07816900
- Testing
- Da-Cheng-Qi Decoction Plus Standard Western Treatment, Standard Western Treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Maxillary Hypoplasia, Malocclusion, Angle Class III
Effect of Bone-anchored Protraction on Maxillary Growth in the Young Child
Class III malocclusions may originate in a retrognathic maxilla, a prognathic mandible or both. Young patients with class III malocclusion and maxillary hypoplasia are conventionally treated with a protraction facemask in order…
- Trial name
- NCT02711111
- Testing
- Face mask, orthodontic bone anchor
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ziekenhuis Oost-Limburg
Malocclusion, Angle Class I
Effect of Different Grafting Material Following Surgically Facilitated Orthodontics Therapy
The purpose of this study is to quantitatively investigate the radiographic changes of alveolar bone, and gingival tissue changes of the mandibular anterior teeth in experimental group A receiving SFOT using freeze-dried…
- Trial name
- NCT06627829
- Testing
- Surgically facilitated orthodontics therapy (SFOT) using allograft, Surgically facilitated orthodontics therapy (SFOT) using xenograft, Usual care
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The University of Texas Health Science Center, Houston
Fallopian Tube Cancer, Ovarian Cancer
Early Chemotherapy Based on CA 125 Level Alone Compared With Delayed Chemotherapy in Treating Patients With Recurrent Ovarian Epithelial , Fallopian Tube, or Primary Peritoneal Cancer
RATIONALE: It is not yet known if treatment for recurrent ovarian epithelial, fallopian tube, or primary peritoneal cancer is more effective if it is begun when blood levels of CA 125 become elevated rather than waiting for other…
- Conditions
- Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
- Trial name
- NCT00002895
- Testing
- chemotherapy
- Where
- 21 sites in Austria, Belgium and 8 more
- Volunteers
- 1,400 people
- Sponsor
- Medical Research Council
Osteoarthritis, Diabetes Mellitus
Comarum Palustre in Knee Osteoarthritis and Diabetes
The study evaluates analgesic, antiinflammatory and metabolic effects of Comarum palustre in patients with knee osteoarthritis (OA) and diabetes mellitus.
- Trial name
- NCT03530930
- Testing
- Comarum Palustre
- Where
- Russia
- Volunteers
- 15 people
- Sponsor
- Federal State Budgetary Scientific Institution, Research Institute of Fundamental and Clinical Immunology
Knee Osteoarthritis
Effects of Muscle Energy Technique in Knee Osteoarthritis Patients
To determine the effectiveness of muscle energy technique along conventional physical therapy after mesenchymal stem cell transplantation in knee Osteoarthritis patients regarding Pain, range of motion, functional disability and…
- Trial name
- NCT05349565
- Testing
- CONVENTIONAL PHYSICAL THERAPY, MUSCLE ENERGY TECHNIQUE
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Post Operative Pain, Inflammation
Clinical and Biochemical Effects Of Cryotherapy Protocols On Mandibular Premolars With Symptomatic Apical Periodontitis
Pain is the major reason for patients' visits to dental clinics.Medications have side effects. Treatments including cryotherapy have been suggested to prevent these side effects.This study will compare the effect of oral and…
- Trial name
- NCT07138365
- Testing
- oral Cryotherapy, Intra radicular Cryotherapy, cold irrigation
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Candidiasis
A Clinical Study Intended To Compare Treatment With Voriconazole To Treatment With Amphotericin Followed By Fluconazole In Patients With Candidemia, A Serious Fungus Infection Of The Blood.
This is a study to investigate the safety and efficacy of voriconazole for the treatment of candidemia in critically ill non-neutropenic patients
- Trial name
- NCT00163111
- Testing
- VFEND® I.V., Oral, Conventional amphotericin B, Diflucan IV, oral
- Volunteers
- 412 people
- Sponsor
- Pfizer
Asthma
Effects of Pilates Exercises in Asthmatic Patients
Asthma is a chronic respiratory disease with high prevalence worldwide, considered an important cause of morbidity, mortality and high economic costs.
- Trial name
- NCT03670654
- Testing
- Pilates, Muscle stretching
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Intradialytic Hypotension, Intensive Care Unit ICU
Using a Hypotension Prediction Index to Prevent Low Blood Pressure During Dialysis in ICU Patients
This single-center, crossover randomized controlled trial (HyPIR-ICU) investigates whether a Hypotension Prediction Index (HPI)-guided management strategy can reduce intradialytic hypotension (IDH) during prolonged intermittent…
- Conditions
- Intradialytic Hypotension, Intensive Care Unit ICU, Hemodialysis Patients
- Trial name
- HyPIR-ICU (NCT07179705)
- Testing
- Hypotensive prediction index, Standard of care monitoring
- Where
- Thailand
- Volunteers
- 46 people
- Sponsor
- Chulalongkorn University
Diabetic Adhesive Capsulitis, Frozen Shoulder
Pain Neuroscience Education and Graded Motor Imagery Combined With Conventional Physiotherapy on Diabetic Adhesive Capsulitis
The purpose of this study is to determine the effects of Pain Neuroscience Education (PNE) and Graded Motor Imagery (GMI) combined with conventional physiotherapy on pain, kinesiophobia, central sensitization, functional…
- Conditions
- Diabetic Adhesive Capsulitis, Frozen Shoulder, Type II Diabetes Mellitus
- Trial name
- NCT07763366
- Testing
- Pain Neuroscience Education (PNE), Graded Motor Imagery (GMI), Conventional Physiotherapy
- Where
- 2 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Aging
NESA Microcurrents on Quality of Life in Geriatric Patients
In recent years, the population of older adults (MA) in the world has been increasing, due to the increase in life expectancy and the decrease in the fertility rate.
- Trial name
- NCT05800431
- Testing
- Non-invasive neuromodulation through the Nesa device
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Las Palmas de Gran Canaria
Platelet Rich Plasma
Platelet Rich Plasma and Diabetic Foot Ulcer
In chronic diabetic foot ulcer, if the conventional dressing fails, new therapeutic options such as recombinant human growth factors and bioengineered skin substitutes may be beneficial, but the cost is a limiting factor.
- Trial name
- NCT04750837
- Testing
- debridement of the wound, platelet rich plasma, conventional dressing
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Zagazig University
Pain, Cervical Spinal Stenosis
KT® in Patients With Cervical Spine Surgery
Aim of the study was to investigate the effect of Kinesio taping application on upper trapezius muscle after cervical spine surgery.
- Conditions
- Pain, Cervical Spinal Stenosis, Disc, Herniated, Cervical Spondylosis
- Trial name
- NCT04039581
- Testing
- Kinesio Taping, Conventional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Marmara University
Text Neck Syndrome
Effect of Myofascial Release Therapy on University Students With Text Neck Syndrome.
This randomized controlled trial aims to determine the effectiveness of myofascial release therapy in university students with text neck syndrome as prolonged smartphone and digital gadgets use has been associated with neck pain…
- Trial name
- NCT07444112
- Testing
- Myofascial Release Therapy, Standard Care (Treatment as Usual)
- Where
- 2 sites in Pakistan
- Volunteers
- 62 people
- Sponsor
- University of Health Sciences Lahore
Menopause
Study of the Effectiveness of Clinical Hypnosis and Self-hypnosis in Relieving Hot Flashes in Menopausal Women
The onset of menopause is accompanied by a significant drop in blood estradiol levels, the main symptom of which is hot flashes. These are present in 80% of menopausal women and are debilitating in 25% of cases.
- Trial name
- HYPNOMENO-2 (NCT07572981)
- Testing
- Hypnosis session, Group self-hypnosis, Unstructured supportive interview
- Where
- France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Toulouse
Chronic Pain, Back Pain
Safety and Efficacy Study of the Evoke™ SCS System With Feedback vs. Conventional Stimulation
The purpose of this study is to evaluate the safety and efficacy of the Saluda Medical Evoke SCS System with feedback control to treat chronic pain of the trunk and/or limbs.
- Conditions
- Chronic Pain, Back Pain, Pain
- Trial name
- EVOKE (NCT02924129)
- Testing
- Evoke Spinal Cord Stimulator (SCS) System
- Where
- 16 sites in United States
- Volunteers
- 134 people
- Sponsor
- Saluda Medical Americas, Inc.
FOOD ALLERGY, FOOD ALLERGY İN CHİLDREN
Evaluation of the Effect of Life With Food Allergy Education
Purpose of the Study It was aimed to reveal the changes in the knowledge levels of mothers with food allergy with Life with Food Allergy Education based on Pender's Health Promotion Model.
- Trial name
- NCT06509737
- Testing
- Face to face group, social mediagroup
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University
Preterm Labor With Intact Membranes, Preterm Birth
Effect of Vaginal Progesterone Treatment on Pregnancy and Newborn Outcomes in Women With Preterm Labor
Preterm labor, which occurs when labor starts before 37 weeks of pregnancy, is a major cause of illness and death in newborns. Babies born too early are at higher risk of breathing problems, low birth weight, infections, and…
- Trial name
- NCT07523295
- Testing
- Nifedipine 20 Mg, Dexamethasone, Progesterone 200 mg vaginal capsules
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Medicare Hospital (Pvt) Limited
Myasthenia Gravis Generalized
PANORAMA: Neuromuscular Organoids for Refractory AChR+ Myasthenia Gravis
Myasthenia gravis (MG) is an autoimmune disease in which autoantibodies attack the neuromuscular junction, the site at which nerve cells communicate with muscle fibres, impairing signal transmission and causing fluctuating muscle…
- Trial name
- PANORAMA (NCT07717281)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
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