Clinical trials: Conventional therapy
Breast Cancer, Wound Dehiscence, Surgical
ciNPT in Autologous DIEP Flap Breast Reconstruction
In women who undergo mastectomy for the treatment of breast cancer, autologous reconstruction using the deep inferior epigastric perforator (DIEP) flap is a common surgical procedure that aims to restore both the appearance and…
- Trial name
- NCT05907941
- Testing
- ciNPT, Conventional Tape Dressings, DIEP Breast Reconstruction
- Volunteers
- 114 people
- Sponsor
- McMaster University
Multiple Sclerosis, Respiration Disorders
Respiratory Muscle Training Program in Patients With Multiple Sclerosis
This is a quasi-experimental pre-post trial aimed at investigating the effects of respiratory muscle training (RMT) as trunk stabilization exercise in patients diagnosed with multiple sclerosis (MS)
- Trial name
- NCT06405451
- Testing
- Conventional treatment, Experimental treatment
- Where
- Spain
- Volunteers
- 27 people
- Sponsor
- Universidad Europea de Madrid
COVID-19, Hypoxemic Respiratory Failure
The Effect of Non-invasive Respiratory Support on Outcome and Its Risks in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2)-Related Hypoxemic Respiratory Failure
Coronavirus disease (COVID-19) can result in severe hypoxemic respiratory failure that ultimately may require invasive mechanical ventilation in the Intensive Care Unit (ICU).
- Trial name
- NORMO2 (NCT06033560)
- Testing
- High flow nasal oxygen (HFNO, more than 15 L/min)
- Where
- Netherlands
- Volunteers
- 6,000 people
- Sponsor
- Amsterdam UMC, location VUmc
Hepatocellular Carcinoma
Role of DEB-TACE Versus c-TACE in Treatment of HCC
Hepatocellular carcinoma (HCC) is listed as the sixth most common cancer worldwide and the third most frequent cause of cancer-related mortality. The majority of HCC cases occurs stem from chronic liver disease and cirrhosis.
- Trial name
- NCT05093920
- Testing
- Doxorubicin-Eluting Beads
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Tendon Injury - Hand, Flexor Tendon Rupture
The Effect of Virtual Reality Based Task Specific Exercises in Patients With Hand Flexor Tendon Injury
This study,the investigators aimed to investigate the effects of virtual reality-based task-specific exercises applied in addition to conventional rehabilitation program on functional level and disease-related quality of life in…
- Trial name
- NCT06198582
- Testing
- Virtual Reality Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Ankara City Hospital Bilkent
Arrhythmias, Cardiac, Atrioventricular Block
ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing
The goal of this observational study is to evaluate the clinical characteristics of patients undergoing permanent cardiac pacing and to compare procedural efficacy and safety of different implantation approaches in the clinical…
- Conditions
- Arrhythmias, Cardiac, Atrioventricular Block, Reduced Systolic Function, Atrial Fibrillation
- Trial name
- TREEBEARD (NCT06324682)
- Testing
- Cardiac pacing - Conventional RV pacing, Cardiac pacing - Conduction System Pacing, Cardiac pacing - Cardiac resynchronization therapy (pacing - CRTP - or defibrillation - CRTD)
- Where
- 31 sites in Italy
- Volunteers
- 8,400 people
- Sponsor
- University Hospital of Ferrara
Physical Therapy
Feasibility Of Oral Sensorimotor Stimulation On Oropharyngeal Dysphagia In Children With Spastic Cerebral Palsy
Children with CP encounter swallow and feeding impairments, especially in infancy and childhood with long meal times with late development of oral motor skills resulting in poor growth.
- Trial name
- NCT04524559
- Testing
- conventional physical therapy training, oral motor training.
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Total Hip Arthroplasty
Does Virtual Reality Rehabilitation Improve Mobility, Balance, and Walking in Patients With Total Hip Arthroplasty?
This study aims to assess the efficacy of virtual reality through the Virtual Reality Rehabilitation System (VRRS) added to conventional rehabilitation versus conventional rehabilitation alone, for improving mobility, balance…
- Trial name
- NCT05173480
- Testing
- Conventional rehabilitation, Virtual Reality Rehabilitation System (VRRS)
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Mauro Crestani
Mandibular Fracture Treatment
Evaluation of Z-shaped Bone Plates in Management of Mandibular Fractures
he goal of this clinical trial is to evaluate Z shaped bone plate in mandibular fracture treatment regarding post operative healing, function restoration and esthetic.
- Trial name
- z-FIX (NCT07184762)
- Testing
- open reduction and internal fixation with bone plate, z-plates., conventional miniplates.
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Suez Canal University
Spastic Cerebral Palsy
Effects of Functional Progressive Strength Training in Children With Spastic Cerebral Palsy
This study focuses on the effects of Functional Progressive Strength Training (FPST) on children with spastic cerebral palsy, a condition characterized by increased muscle tone that affects movement.
- Trial name
- NCT06407869
- Testing
- Functional Progressive Strength Training, Control
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Bronchiectasis, Non-cystic Fibrosis Bronchiectasis
Bronchiectasis Phenotype Identification Model
The Bronchiectasis Phenotype Identification Model (BPIM) is a prospective observational development-validation study within the Assiut University bronchiectasis translational research platform.
- Conditions
- Bronchiectasis, Non-cystic Fibrosis Bronchiectasis, Bronchiectasis With Acute Exacerbation
- Trial name
- BPIM (NCT07599969)
- Where
- Egypt
- Volunteers
- 750 people
- Sponsor
- Assiut University
Virtual Reality, Intensive Care Unit Acquired Weakness
The Effects of Virtual Reality in Intensive Care Patients
Weakness of respiratory muscles delays weaning from the ventilator, prolongs hospital stay and increases treatment costs. Conventional treatments for respiratory muscles reverse these negative effects.
- Trial name
- NCT06442254
- Testing
- Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istinye University
Oesophageal Cancer, Gastric Cancer
Modulated Mid-frequency Whole-body Electromyostimulation and Nutritional Therapy in Gastrointestinal Cancer Patients
The purpose of this study is to assess the efficacy of modulated mid-frequency whole-body electromyostimulation (WB-EMS) combined with nutritional therapy in patients with gastrointestinal cancer.
- Conditions
- Oesophageal Cancer, Gastric Cancer, Duodenal Cancer, Colorectal Cancer
- Trial name
- MOMENT (NCT06414122)
- Testing
- mid-frequency whole-body electromyostimulation (WB-EMS), conventional exercise training, nutritional therapy
- Where
- Germany
- Volunteers
- 88 people
- Sponsor
- University of Cologne
Stroke, Upper Extremity Dysfunction
Exoskeleton-assisted Upper Limb Rehabilitation After Stroke
In recent studies, it has been observed that robotic devices make a positive contribution to motor recovery and the activities of daily living.
- Trial name
- NCT04353622
- Testing
- Exoskeleton robot for upper extremity, Conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Marmara University
Convulsion, Non-Epileptic
Retraining and Control Therapy (ReACT)- Adults
The purpose of this study is to assess sense of control and catastrophic symptom expectations as targets for Retraining and Control Therapy (ReACT- an intervention focused on changing behaviors and thoughts) for treatment of…
- Trial name
- ReACT (NCT06570954)
- Testing
- ReACT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Alabama at Birmingham
Post-Concussion Syndrome, Mild Traumatic Brain Injury
Cervico-vestibular Rehabilitation for Mild Traumatic Brain Injury
Neck pain, dizziness and headache are common symptoms following mild traumatic brain injury (mTBI). The efficacy of cervical spine and vestibular-ocular system impairments intervention need to be determined.
- Conditions
- Post-Concussion Syndrome, Mild Traumatic Brain Injury, Vestibular Disorder, Whiplash Injuries
- Trial name
- NCT03677661
- Testing
- Conventional approach, Personalized rehabilitation program
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laval University
Diabetes Mellitus., Chronic Periodontitis
Periodontal Treatment in Non-controlled Type 2 Diabetes Mellitus Patients. Clinical Trial
Periodontitis is an infectious disease that destroys the tooth supporting tissues and triggers a local and systemic immune response.
- Trial name
- FONIS12I2106 (NCT01904422)
- Testing
- conventional periodontal treatment
- Where
- Chile
- Volunteers
- 87 people
- Sponsor
- Universidad de los Andes, Chile
Prostate Cancer
Enhanced Systemic Combined With Local Treatment for Primary and Metastatic Lesions in Oligo-metastatic Prostate Cancer
Oligo-metastatic prostate cancer (OMPCa) is considered as an intermediated state between localized and poly-metastatic disease. Various retrospective studies and prospective clinical trials are carrying out to validate whether…
- Trial name
- NCT05212857
- Testing
- Leuprolide acetate, Goserelin acetate, Triptorelin acetate
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Fudan University
Schizophrenia
Dopaminergic, Functional, Structural, and Cognitive Disturbances in First-episode Schizophrenia
We wanted to compare dopamine D2 receptor activity, brain structure, brain function, sensory gating and cognition in neuroleptic-naive schizophrenic patients and matched healthy controls.
- Trial name
- NCT00206960
- Testing
- zuclopenthixol, risperidone
- Where
- 6 sites in Denmark
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Birte Glenthoj
Dental Implant Placement, Ozone Therapy
Ozone Versus Conventional Socket Disinfection for Primary Dental Implant Stability
This randomized split-mouth controlled clinical trial aims to compare the effects of ozone and conventional implant site disinfection on primary and early secondary implant stability.
- Trial name
- NCT07687680
- Testing
- Ozone Implant Site Disinfection, Conventional Socket Disinfection
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Zeliha Başak Çakır Erdil
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