Clinical trials: Conventional therapy
Acceleration of Procedure, Reduction of Number of Transports and Transfers
The Multifunctional Image Guided Therapy Suite (MIGTS) in Emergency Multiple Trauma Care
Controlled clinical intervention study comparing the treatment of multiple trauma patients in a newly developed combined diagnostic and operation room, the multifunctional image guided therapy suite (MIGTS) versus controls.
- Conditions
- Acceleration of Procedure, Reduction of Number of Transports and Transfers, Involved Staff Member's Evaluation
- Trial name
- MIGTS (NCT00772213)
- Testing
- MIGTS treatment
- Where
- Switzerland
- Volunteers
- 168 people
- Sponsor
- University Hospital, Basel, Switzerland
Prostate Cancer
FOcal Radiation for Oligometastatic Castration-rEsistant Prostate Cancer (FORCE)
This clinical trial will determine whether the addition of radiotherapy to standard of care systemic therapy improves objective progression-free survival compared to systemic therapy alone in patients with oligometastatic…
- Trial name
- NCT03556904
- Testing
- Ablative Radiation Therapy, Hormone therapy or chemotherapy
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- University of Michigan Rogel Cancer Center
Low Back Pain
Efficacy of Augmented Feedback on Lumbar Postural and Movement Control During Physiotherapy and Home Exercise
Exercise therapy is effective in improving pain experience and disability in patients with non-specific low back pain (NSLBP) and movement/postural control impairments.
- Trial name
- NCT03841552
- Testing
- Augmented Feedback, Control Group
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Zurich University of Applied Sciences
Chronic Shoulder Pain
Injection in Patients With Chronic Shoulder Pain
Background: Chronic shoulder pain (CSP) is a musculoskeletal disease characterized by pain lasting more than 3 months. Purpose: This study aimed to determine whether pre-treatment injection in CSP treatment contributes to pain…
- Trial name
- NCT06135038
- Testing
- Suprascapular nerve block with physical therapy, Group 2 Physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Uşak University
Melanoma, Non-small Cell Lung Cancer
Safety and Efficacy of Chimeric Antigen Receptor T Lymphocytes for Patients With Intermediate and Advanced Tumors
This was a single arm, open-label, single center, cohort study to determine the efficacy and safety of AMT-116 CAR-T cells in patients with moderate or far advanced non-small cell lung carcinoma (NSCLC) and squamous cell cancer…
- Conditions
- Melanoma, Non-small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma
- Trial name
- NCT05117138
- Testing
- AMT-116 CAR-T cells, AMT-253 CAR-T cells
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Beijing Immunochina Medical Science & Technology Co., Ltd.
Brain and Central Nervous System Tumors
Stereotactic Radiosurgery and Radiation Therapy in Treating Patients With Glioblastoma Multiforme
RATIONALE: Stereotactic radiosurgery may be able to send x-rays directly to the tumor and cause less damage to normal tissue. Radiation therapy uses high-energy x-rays to kill tumor cells.
- Trial name
- NCT00253448
- Testing
- radiation therapy, stereotactic radiosurgery
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Case Comprehensive Cancer Center
Kidney Diseases, Hemodialysis Complication
Hemodialysis Adequacy Using a Heparin-grafted Dialyzer and a Citrate-enriched Dialysate
After providing informed consent, patients will be randomized to either the intervention treatment ("EvoCit procedure") or the control treatment ("EvoHep procedure").
- Conditions
- Kidney Diseases, Hemodialysis Complication, End Stage Renal Disease
- Trial name
- EvoCit-HD (NCT03887468)
- Testing
- EvoCit, EvoHep
- Where
- 2 sites in Belgium
- Volunteers
- 38 people
- Sponsor
- Universitair Ziekenhuis Brussel
Mouth, Edentulous, Complete Edentulism
Cost-effectiveness of the Single-implant Mandibular Overdenture Versus Mandibular Conventional Denture
This is a randomized clinical trial designed to assess the 1-year effectiveness of two treatment modalities for the mandibular edentulists: conventional complete dentures and single-implant mandibular overdenture.
- Trial name
- NCT03463174
- Testing
- Mandibular overdenture, Mandibular complete denture
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Knee Osteoarthristis
Efficacy of Virtual Reality Based Exercise Regimes on Kinesiophobia, Pain and Functional Disability in Patients With Knee Osteoarthritis
Knee Osteoarthritis is one of the most prevalent degenerative conditions in Pakistan. Although a variety of Physical therapy treatments have been proven to be beneficial in patients with early stages of knee Osteoarthritis.
- Trial name
- NCT05777421
- Testing
- Conventional Physical Therapy for Knee Osteoarthriths, Virtual Reality-Based Therapeutic Exercise regimes
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Foundation University Islamabad
Distal Radius Fracture
Complex Decongestive Therapy on Distal Radius Fracture
Trauma results in inflammatory reactions accompanied by high protein edema. Trauma can also reduce the carrying capacity of the lymphatic system below normal lymphatic load, leading to exposure of lymphedema.
- Trial name
- NCT04484584
- Testing
- complex decongestive therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Length of Hospital Stay
A Retrospective Study of Early Postoperative Mobilization in the Recovery of Patients With Oral Head and Neck Tumors Who Underwent Flap Reconstruction
All patients with head and neck cancers and osteomyelitis who underwent vascularized flap reconstruction at Shanghai Ninth People's Hospital (North Campus), Shanghai Jiao Tong University, from February 2020 to July 2021 were the…
- Trial name
- NCT05851833
- Testing
- Early Mobilization
- Where
- China
- Volunteers
- 244 people
- Sponsor
- Jie He, MD
Down Syndrome
Effects of Cuevas Medek Exercises on Trunk Control and Balance in Children With Down Syndrome
Down syndrome, a genetic condition caused by the presence of an extra copy of chromosome 21. This additional genetic material affects the normal development of the brain and body, leading to intellectual and developmental delays.
- Trial name
- NCT06461858
- Testing
- cuevas medek technique (exercise), conventional therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Stroke, Hemiparesis
Assessment of a Physio-neuro Platform (SynPhNe) for Home-based Retraining of Hand Function in Stroke Survivors
The goal of this study is to: 1. Assess the usability of the SynPhNe device in a home environment. 2. Evaluate the efficacy of the SynPhNe home use device to improve motor hand function in chronic stroke subjects as compared to…
- Trial name
- NCT02896348
- Testing
- SynPhNe platform, Conventional therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Spaulding Rehabilitation Hospital
POAG, MIGS
Efficacy and Safety of iStent Inject and Inject W in the Management of Primary Open-angle Glaucoma
Primary open-angle glaucoma (POAG) is a chronic eye disease in which the only validated treatment is to lower intraocular pressure (IOP). It is the 2nd leading cause of blindness worldwide.
- Trial name
- EII (NCT05062668)
- Testing
- cataract operation and istent, cataract operation only
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Lung Cancer
Erlotinib, Paclitaxel, and Carboplatin Combined With Radiation Therapy for Stage III Non-Small Cell Lung Cancer
RATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor…
- Trial name
- NCT00278148
- Testing
- carboplatin, Erlotinib, paclitaxel
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Nathan Pennell, MD, PhD
Glaucoma
EX-PRESS® P-50 and EX-PRESS® P-200
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to assess long term clinical performance and safety outcomes for EX-PRESS Glaucoma Filtration Devices Models P-50 and P-200.
- Trial name
- NCT06119178
- Testing
- EX-PRESS P-50 filtration device, EX-PRESS P-200 filtration device
- Where
- 2 sites in United States
- Volunteers
- 122 people
- Sponsor
- Alcon Research
Tachycardia, Diabetes Mellitus
Multicenter Automatic Defibrillator Implantation Trial With Subcutaneous Implantable Cardioverter Defibrillator
The MADIT S-ICD trial was designed to evaluate if subjects with a prior myocardial infarction, diabetes mellitus and a relatively preserved ejection fraction of 36-50% will have a survival benefit from receiving a subcutaneous…
- Conditions
- Tachycardia, Diabetes Mellitus, Cardiovascular Disease
- Trial name
- MADIT S-ICD (NCT02787785)
- Testing
- Subcutaneous Implantable Cardioverter Defibrillator
- Where
- 49 sites in United States, Germany and 5 more
- Volunteers
- 40 people
- Sponsor
- Boston Scientific Corporation
Nursing Caries, Pain
Effect of Music on Pain in Cancer Patients in Palliative Care Service: a Randomized Controlled Study
Background: Palliative care services can be applied in chronic, life-threatening conditions such as cancer, and provide physical, mental and psychological support to patients worldwide.
- Conditions
- Nursing Caries, Pain, Music Therapy
- Trial name
- nursingcare (NCT04486443)
- Testing
- music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- gönül düzgün
Metabolic Syndrome, Lipid Profile
Gluten Free Diet on Metabolic Syndrome
This study benefits the community by highlighting the potential of a gluten-free diet as a non-pharmacological, effective approach to managing obesity and type 2 diabetes.
- Conditions
- Metabolic Syndrome, Lipid Profile, HOMA-IR, Weight Change, Body
- Trial name
- NCT07127055
- Testing
- No intervention, gluten free diet
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- University of Lahore
Thoracic Diseases
Effect of Manual Chest Wall Vibration on Respiratory Function and Chest Tube Duration After Thoracic Surgery
This study was conducted to determine the effects of a manual vibration technique applied to the chest wall on the duration of chest tube placement, secretion clearance, and hemodynamic parameters in patients with chest tubes.
- Trial name
- NCT07549555
- Testing
- Chest Wall Oscillation, Conventional Control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
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