Clinical trials: Conventional therapy, completed
Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction
Bevacizumab and Combination Chemotherapy Before Surgery in Treating Patients With Locally Advanced Esophageal or Stomach Cancer
This pilot phase II trial studies how well giving bevacizumab and combination chemotherapy together before surgery works in treating patients with locally advanced esophageal or stomach cancer.
- Conditions
- Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction, Diffuse Adenocarcinoma of the Stomach, Intestinal Adenocarcinoma of the Stomach
- Trial name
- NCT01212822
- Testing
- bevacizumab, oxaliplatin, leucovorin calcium
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Fox Chase Cancer Center
Photochemotherapy Reaction, Dental Pulp Necrosis
Antimicrobial Photodynamic Therapy Associated With the Conventional Endodontic Treatment: A Clinical and Microbiological Study
Microorganisms play a critical role in the etiology and pathogenesis of apical periodontitis. Enterococcus faecalis and Candida sp. are frequently associated with persistent infections.
- Conditions
- Photochemotherapy Reaction, Dental Pulp Necrosis, Polymerase Chain Reaction, Infection
- Trial name
- NCT03212729
- Testing
- ANTIMICROBIAL PHOTODYNAMIC THERAPY, Conventional endodontic treatment
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Prostate Cancer
RADAR Trial - Randomised Androgen Deprivation and Radiotherapy
The principal objectives of the RADAR trial is to address the hypotheses; 1) that 18 months androgen deprivation in conjunction with radiotherapy is superior to 6 months androgen deprivation prior to and during radiotherapy; 2)…
- Trial name
- NCT00193856
- Testing
- Leuprorelin Acetate, Zoledronic Acid, Conventional external beam therapy
- Where
- 24 sites in Australia, New Zealand
- Volunteers
- 1,071 people
- Sponsor
- Trans Tasman Radiation Oncology Group
Intrahepatic Cholangiocarcinoma, Peripheral Cholangiocarcinoma
Hepatic Arterial Infusion With Floxuridine and Dexamethasone in Combination With Gemcitabine as Adjuvant Treatment After Resection of Intrahepatic Cholangiocarcinoma
This is a Phase I study, which means we want to find out what effects, good and/or bad, this combination of drugs may have on the patient and the liver cancer at different dose levels.
- Conditions
- Intrahepatic Cholangiocarcinoma, Peripheral Cholangiocarcinoma, Cholangiolar Carcinoma, Cholangiocellular Carcinoma) (ICC)
- Trial name
- NCT01938729
- Testing
- Liver resection and placement of hepatic artery infusion pump, FLOXURIDINE, DEXAMETHASONE
- Where
- 5 sites in United States
- Volunteers
- 8 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Schizophrenia
Efficacy Study of Switching Stabilized Schizophrenic Patients From Conventional to Atypical Antipsychotic Treatment
The objective of this study is to demonstrate that there is a benefit in switching chronic schizophrenic patients from conventional antipsychotic to olanzapine in terms of efficacy, neurological safety and patient's outcome.
- Trial name
- NCT00191555
- Testing
- olanzapine, haloperidol
- Where
- 62 sites in France
- Volunteers
- 360 people
- Sponsor
- Eli Lilly and Company
Colorectal Cancer
GM-CSF and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Colon Cancer
RATIONALE: Colony-stimulating factors, such as GM-CSF, may increase the number of immune cells found in bone marrow or peripheral blood and may help the immune system recover from the side effects of chemotherapy or kill tumor…
- Trial name
- NCT00262808
- Testing
- sargramostim, fluorouracil, leucovorin calcium
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Rochester
DeQuervain Tendinopathy, DeQuervain's Tenosynovitis
Graston Technique and Myofascial Release in De Quervain's Tenosynovitis
This research compares how well the Graston Technique and Myofascial Release Therapy work to reduce pain and improve flexibility for those struggling with De Quervain's tenosynovitis
- Conditions
- DeQuervain Tendinopathy, DeQuervain's Tenosynovitis, DeQuervain's Tenosynovitis of the Wrist, DeQuervains Tenosynovitis
- Trial name
- NCT07587489
- Testing
- Graston Technique, Myofacial Release Therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Elite College of Management Sciences, Gujranwala, Pakistan
Alveolar Bone Atrophy, Bone Resorption
Effect of Citric Acid Demineralization on Autogenous Bone Blocks Consolidation in Humans
This study evaluates the effect of citric acid demineralization in autogenous bone blocks consolidation. Half of participants will receive citric acid treatment at the bone block and recipient site.
- Trial name
- NCT03357068
- Testing
- Control, Acid
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Sao Paulo
Upper Trapezius Trigger Points
Effects of IC With and Without MET on Upper Trapezius Trigger Points
the aim of the study is to check the effects of ischemic compression with and without muscle energy technique on Pain, Range of motion, and Functional Disability on myofascial trigger points in the upper trapezius.
- Trial name
- NCT05415813
- Testing
- Ischemic Compression, Ischemic compression with Muscle Energy Technique
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- University of Lahore
Low Birth Weight Among Neonates
Randomized, Controlled Trial of Kangaroo Mother Care in Increasing the Rate of Weight Gain Among Neonates
A randomized, controlled trial of Kangaroo Mother Care (KMC) to determine the effectiveness in increasing the rate of weight gain among low birth weight neonates.
- Trial name
- NCT02085382
- Testing
- Kangaroo Mother Care, Conventional Mother Care
- Where
- Philippines
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of the Philippines
Coronary Artery Disease
Side Branch FFR After Provisional Stenting
The purpose of this study is to predict any changes in the side branch after stenting the main branch blood vessel using three dimensional intravascular images. (Frequency domain optical coherence tomography FD OCT).
- Trial name
- ORBID-FFR (NCT03115580)
- Testing
- Rotational atherectomy, Cutting Balloon Angioplasty
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anti-CD30, Brentuximab
Anti-CD30 (Brentuximab Vedotin) With AVD Versus ABVD Chemotherapy Protocol Frontline Therapy in Patients With Advanced Classical Hodgkin Lymphoma
This study will be held in the clinical oncology department, Helwan University, and Police Hospital, aiming to compare the efficacy and safety of anti-CD30 (BV) + Doxorubicin, Vinblastine, and Dacarbazine (AVD) versus the…
- Conditions
- Anti-CD30, Brentuximab, Doxorubicin, Vinblastine
- Trial name
- NCT07171827
- Testing
- Brentuximab Vedotin + Doxorubicin, Vinblastine, and Dacarbazine, Doxorubicin, Bleomycin, Vinblastine, and Dacarbazine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Helwan University
Oral Mucositis (Ulcerative) Due to Radiation
Melatonin for Prevention of Radiation Induced Oral Mucositis
The main aim of this study was to evaluate the effectiveness of melatonin in prevention of radiation induced oral mucositis clinically and biochemically.
- Trial name
- NCT03833570
- Testing
- Rapid Release Capsules Melatonin, 10 mg, Miconaz oral gel, BBC oral spray
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman
Facial Acne Vulgaris
Retinyl Palmitate-loaded Ethosomes in Acne Vulgaris
Acne is a chronic inflammatory dermatosis of the pilosebaceous unit. Topical treatment is the first choice in mild and moderate cases of acne, especially topical retinoids.
- Trial name
- NCT04080869
- Testing
- retinyl palmitate, Tretinoin
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma
Ruxolitinib Phosphate, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
This phase I/II trial studies the side effects and the best dose of ruxolitinib phosphate when given together with paclitaxel and carboplatin and to see how well they work in treating patients with stage III-IV epithelial…
- Conditions
- Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube High Grade Serous Adenocarcinoma, FIGO Stage III Ovarian Cancer 2014
- Trial name
- NCT02713386
- Testing
- Carboplatin, Paclitaxel, Ruxolitinib Phosphate
- Where
- 110 sites in United States
- Volunteers
- 147 people
- Sponsor
- NRG Oncology
Vascular Access Complications
Comparison of AccuCath IV Catheter and Conventional IV Catheter in Interventional Radiology
The study will test a hypothesis that the AccuCath™ System will have a higher rate of successful first attempt peripheral IV placement and higher clinician and patient satisfaction compared to Conventional IV Catheters.
- Trial name
- NCT01940354
- Testing
- AccuCath IV Catheter System, Conventional IV Catheter System
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Covid19
Inhalation of Vapor With Medication (Diclofenac Sodium, Menthol, Methyl Salicylate and N-Acetyl Cysteine) Reduces Oxygen Need and Hospital Stay in COVID-19 Patients - A Case Control Study
Background: In the midst of the devastating COVID pandemic where there is no specific and effective treatment, traditional therapy may help to ease the patient's suffering.
- Trial name
- NCT04900129
- Testing
- Menthol 0.02%, Methyl salicylate 0.05%, N- Acetyl cysteine 1.2 gm%, and Diclofenac sodium 1gm%
- Where
- Bangladesh
- Volunteers
- 43 people
- Sponsor
- Sher-E-Bangla Medical College
Acute Myeloid Leukemia (AML)
Allogenic Stem Cell Transplantation for Children, Adolescents and Young Adults With Relapsed or Refractory AML
1. To evaluate whether stem cell transplantation from a matched sibling donor is equivalent to a matched unrelated donor in in a second complete remission of acute myeloid leukemia (AML). 2.
- Trial name
- NCT00606723
- Testing
- Hematopoietic stem cells from bone marrow or peripheral blood
- Where
- 24 sites in Austria, Czechia and 1 more
- Volunteers
- 154 people
- Sponsor
- Hannover Medical School
White Spot Lesion, Remineralization
Effectiveness of MI Paste Plus and Remin Pro on Remineralization of Post-Orthodontic White Spot Lesions
One of the most undesired side effects of fixed orthodontic treatment is white spot lesions (WSLs), that appear on the buccal surface of teeth and cause aesthetic problems.
- Trial name
- NCT06178042
- Testing
- MI Paste Plus, Remin Pro, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Izmir Katip Celebi University
Cervicogenic Headache
Suboccipital Muscle Inhibition Technique vs Rocabado Exercises on Cervicogenic Headache
The purpose of the study is to explore the effectiveness of Suboccipital muscle inhibition technique vs Rocabado exercises on cervicogenic headache.
- Trial name
- NCT06938256
- Testing
- Suboccipital Muscle Inhibition, Rocabado 6x6 Exercises
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
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