Clinical trials: Conventional therapy, completed
Blood Pressure Control, Kidney Transplant Recipient
Chronotherapy Versus Conventional BP Control to Correct Abnormal Circadian BP Pattern in Kidney Transplant Recipients
The purpose of this study is to identify and manage factors related to blood pressure control that impact organ function and survival in kidney transplant recipients.
- Trial name
- NCT01093703
- Testing
- Medication Adjustment
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Mayo Clinic
Severe Sepsis, Septic Shock
Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial)
The purpose of this trial is to determine the influence of colloid versus crystalloid volume resuscitation and of intensive vs conventional insulin therapy on morbidity and mortality of patients with severe sepsis and septic…
- Trial name
- NCT00135473
- Testing
- 10% Hemohes® (10% Hydroxyethyl starch), Sterofundin® (Ringer lactate solution), Actrapid® (Insulin)
- Where
- 16 sites in Germany
- Volunteers
- 600 people
- Sponsor
- SepNet - Critical Care Trials Group
Intestinal Obstruction, Postoperative Complications
Impact of Interactive Video Health Intervention on Quality of Life After Bowel Obstruction Surgery
Objective: To investigate the multidimensional effects of an interactive video health intervention on the quality of life and clinical rehabilitation indicators of patients with early postoperative bowel obstruction.
- Trial name
- NCT07258017
- Testing
- Conventional care, Interactive Video Health Intervention
- Where
- China
- Volunteers
- 462 people
- Sponsor
- Changsha Fourth Hospital
Rheumatoid Arthritis
A Study to Evaluate the Effectiveness and Safety of SKI-O-703 in Patients Experiencing Active Rheumatoid Arthritis Despite Treatment With Conventional Therapies.
This study will evaluate the safety and efficacy of SKI-O-703 compared with placebo, in patients with active rheumatoid arthritis (RA) who have had an inadequate response to conventional synthetic disease-modifying agents.
- Trial name
- NCT04057118
- Testing
- SKI-O-703
- Where
- 40 sites in United States, Czechia and 3 more
- Volunteers
- 163 people
- Sponsor
- Oscotec Inc.
Total Knee Arthroplasty, Total Knee Replacement
Using Mobilization Exercises on Total Knee Arthroplasty Rehabilitation
There is no definite evidence about the most effective treatment approach in early-stage rehabilitation after total knee arthroplasty surgery.
- Trial name
- NCT03215160
- Testing
- Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University
Dialysis; Complications, Hemodialysis Complication
Conventional Hemodialysis Versus Post-Dilution Hemofiltration in Incident RRT
Patients with chronic kidney disease (CKD) with criteria for renal replacement therapy (RRT) including uremic syndrome, have a stable state of hyperosmolarity due to urea despite not being an osmotically inactive ion.
- Conditions
- Dialysis; Complications, Hemodialysis Complication, Cerebral Edema, Cognitive Impairment
- Trial name
- DA-VINCI (NCT05060159)
- Testing
- Hemofiltration
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Patellofemoral Pain Syndrome
Conventional Home Exercise Programs Versus Electronic Home Exercise Versus Artificial Intelligence "Virtual Therapy" for Anterior Knee Pain
This is a clinical research trial to evaluate the efficacy of delivering exercise therapy for knee pain via the Internet utilizing an algorithm designed to adjust a home exercise program based on user input.
- Trial name
- NCT01696162
- Testing
- Algorithm based Exercise Videos, PDF Exercise Sheets, Limited Exercise Videos
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Simpletherapy
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
Gemcitabine, Paclitaxel, and Cisplatin in Treating Patients With Advanced Cancer of the Urothelium
RATIONALE: Drugs used in chemotherapy, such as gemcitabine, paclitaxel, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00310011
- Testing
- cisplatin, gemcitabine hydrochloride, paclitaxel
- Where
- 3 sites in United States
- Volunteers
- 71 people
- Sponsor
- Wake Forest University Health Sciences
Diabetic Foot Ulcer, Healing Delayed
Mean Healing Time of Wound After Vacuum Assisted Closure (VAC) Versus Conventional Dressing in Diabetic Foot Ulcer Patients
Comparison the mean healing time of wound after vacuum assisted closure(VAC) versus conventional dressing(CD) in diabetic foot ulcer(DFU) patients.
- Conditions
- Diabetic Foot Ulcer, Healing Delayed, Wound; Foot, Diabetes Mellitus
- Trial name
- NCT04959071
- Testing
- Vacuum assisted closure VAC vs conventional dressing
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Bahria University
Maxillary Cyst
Impact of Photobiomodulation Bone Healing Following Cystic Enucleation
A well-known issues confronted by oral and maxillofacial specialists are the osseous defects and dead spaces and how can be obliterated and augmented in the facial regions.
- Trial name
- NCT06759571
- Testing
- low level laser treatment
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Minia University
Hepatocellular Carcinoma
TACE in Combination With PD-1/PD-L1 Inhibitors and Molecular Target Therapies for Advanced HCC
The purpose of this study is to evaluate the safety and efficacy of transarterial chemoembolization (TACE) in combination with immune checkpoint inhibitors (ICIs) and molecular target therapies in patients with advanced-stage…
- Trial name
- CHANCE2201 (NCT05332821)
- Testing
- PD-1/PD-L1 inhibitors+VEGF-TKI/bevacizumab, TACE
- Where
- 2 sites in China
- Volunteers
- 1,244 people
- Sponsor
- Zhongda Hospital
Pulmonary Embolism
Air Versus Oxygen for Intermediate-Risk Pulmonary Embolism (AIRE)
The primary objective is to evaluate the efficacy of the treatment with supplementary oxygen added to conventional anticoagulant treatment in patients with Intermediate-risk pulmonary embolism.
- Trial name
- AIRE (NCT04003116)
- Testing
- Oxygen gas
- Where
- 7 sites in Spain
- Volunteers
- 70 people
- Sponsor
- Ministry of Health, Spain
Post-COVID-19 Related Fatigue
Disease-related Fatigue Monitoring Based on Body Signals Measured on the Skin
This study investigates the use of physiological parameters as predictors of disease-related fatigue. For that purpose, wearable devices are used to monitor post-COVID-19 patients during their stay in a rehabilitation clinic.
- Trial name
- Fatignals (NCT05853055)
- Testing
- Respiratory training
- Where
- Switzerland
- Volunteers
- 33 people
- Sponsor
- Simon Annaheim
Metabolic Syndrome
Influence of Herbal Infusion on Metabolic Syndrome
After taking written informed consent patients, the selected participants were divided into control and experimental group randomly.
- Trial name
- NCT06728449
- Testing
- Cumin tea, Ginger Tea, Lemon Peel Tea
- Where
- Pakistan
- Volunteers
- 330 people
- Sponsor
- University of Lahore
Schizophrenia, Schizotypal and Delusional Disorders
The Efficacy of Using a Smartphone App to Support Shared Decision Making in People With a Diagnosis of Schizophrenia
This study investigates the effects of using a smartphone app to support shared decision making (SDM) for people with schizophrenia-spectrum disorders in an outpatient treatment setting.
- Trial name
- NCT03554655
- Testing
- Momentum app
- Where
- 7 sites in Denmark
- Volunteers
- 194 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Periodontitis, Periodontal Intrabony Defects
Impact of Platelet-Rich Fibrin on Periodontal Tissue Regeneration
The purpose of this research is to assess the efficacy of Platelet-Rich Fibrin (PRF) in the regeneration of periodontal tissues in patients suffering from periodontal disease.
- Trial name
- NCT07395726
- Testing
- Open Flap Debridement, Platelet-Rich Fibrin with Open Flap Debridement
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Liver Cirrhosis, Hyponatremia
Efficacy and Safety of Tolvaptan in Cirrhotic Patients With Hyponatremia
This is a phase IV, open-label, prospective cohort study for 7 days.The recommended starting dose of tolvaptan is 15 mg daily orally.
- Trial name
- OASIS (NCT01850940)
- Testing
- Tolvaptan, conventional thearpy
- Where
- 19 sites in China
- Volunteers
- 98 people
- Sponsor
- Beijing Friendship Hospital
Disorders of Consciousness Due to Severe Brain Injury
Hand Jing-Well Points Stimulation to Treat Disorders of Consciousness
The purpose of this academic lead study is to explore the ideal stimulation strategies at Hand twelve jing-well points in patients with disorders of consciousness.
- Trial name
- Wells-DoC (NCT06927713)
- Testing
- Bloodletting Acupuncture, Transcutaneous electrical stimulation
- Where
- 4 sites in China
- Volunteers
- 59 people
- Sponsor
- Xijing Hospital
Neck Pain
Addition of 3D Posture Corrective Orthosis to A Multimodal Program of Treatment Of NSNP.
Nonspecific neck pain (NSNP) is one of the most common musculoskeletal problems treated by orthopaedic physicians and physiotherapists .
- Trial name
- NCT03331120
- Testing
- ambulatory mirror image functional re-training through wearing 3D adjustable cervicothoracic Posture Corrective Orthotic(CTPCO)
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Tongji Hospital
Esophageal Cancer
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Esophageal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00021320
- Testing
- cisplatin, fluorouracil, paclitaxel
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Fox Chase Cancer Center
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