Clinical trials: Conventional therapy
Atrial Fibrillation, Persistent
Waveform Periodicity Analysis of Complex Fractionated Electrograms in Patients With Persistent Atrial Fibrillation
Atrial fibrillation (AF) has been the most frequently occurring, sustained arrhythmia, which causes significant morbidity and mortality. AF may not always be a totally random process.
- Trial name
- NCT05426603
- Testing
- Pulmonary vein isolation, Substrate ablation(PRISM based)
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Stage III Vulvar Cancer AJCC v7, Stage IIIA Vulvar Cancer AJCC v7
Radiation Therapy, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Locally Advanced Squamous Cell Cancer of the Vulva
This phase II trial studies how well radiation therapy works when given with gemcitabine hydrochloride and cisplatin work in treating patients with squamous cell cancer of the vulva that has spread from where it started to nearby…
- Conditions
- Stage III Vulvar Cancer AJCC v7, Stage IIIA Vulvar Cancer AJCC v7, Stage IIIB Vulvar Cancer AJCC v7, Stage IIIC Vulvar Cancer AJCC v7
- Trial name
- NCT01595061
- Testing
- Cisplatin, Gemcitabine Hydrochloride, Intensity-Modulated Radiation Therapy
- Where
- 193 sites in United States
- Volunteers
- 57 people
- Sponsor
- Gynecologic Oncology Group
Effects of Immunotherapy, Metastatic/Recurrent Cervical Cancer
Axalimogene Filolisbac (ADXS11-001) High Dose in Women With Human Papillomavirus (HPV) + Cervical Cancer
To evaluate the tolerability and safety of axalimogene filolisbac 1 x 10^10 colony forming units (cfu) administered with prophylactic premedication in repeating 3-dose study cycles in women with persistent, metastatic, or…
- Conditions
- Effects of Immunotherapy, Metastatic/Recurrent Cervical Cancer, Cervical Adenocarcinoma, Cervical Adenosquamous Cell Carcinoma
- Trial name
- NCT02164461
- Testing
- Axalimogene filolisbac
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Advaxis, Inc.
Frail Older Adults
CogXergaming to Promote Physical Activity and Cognitive Function in Frail Older Adults
Due to the age associated sarcopenia and reduced cardiovascular fitness, frail older adults experience significant decrease in physical function which comprises of mobility, endurance, muscle strength and balance control.
- Trial name
- NCT04534686
- Testing
- CogXergaming, Matter of Balance Training
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Illinois Chicago
Cerebral Palsy
Training With Virtual Reality in Upper Arm Reaching of Children With Cerebral Palsy
The objective of this study was to evaluate the effects of training with Virtual Reality in the movement range of children with Cerebral Palsy spastic hemiparetic.The study protocol consisted of two days of training and 1…
- Trial name
- NCT04483388
- Testing
- Training with Virtual Reality, Conventional Training
- Volunteers
- 12 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Greater Trochanteric Pain Syndrome
ESWT vs Conventional Physical Therapy in Greater Trochanteric Pain Syndrome
This study aims to compare the effectiveness of Extracorporeal Shockwave Therapy (ESWT) with conventional physical therapy in patients with Greater Trochanteric Pain Syndrome (GTPS).
- Trial name
- NCT07243327
- Testing
- Extracorporeal Shockwave Therapy (ESWT), TENS; Hot Pack; Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Partial Edentulism Class 1 or Class 2
Comparative Evaluation of Artificial Intelligence-Assisted Versus Conventional Guided Implant Planning in Free End Saddle Cases
This study aims to compare the accuracy and clinical performance of artificial intelligence (AI)-assisted implant planning with conventional human-based implant planning in patients presenting with free-end saddle edentulous…
- Trial name
- NCT07891442
- Testing
- Dental implant palcement
- Volunteers
- 20 people
- Sponsor
- Mariam Morcos Nasr
High Risk Prostate Carcinoma, Prostate Cancer
Study Evaluating the Efficacy and Safety of Darolutamide and Stereotactic Dose Escalated Radiotherapy in Patients With Localized Prostate Cancer and High-risk Features of Relapse
PEACE 7 is an international, multicenter, randomized, open-label phase III study that aims at evaluating the efficacy and safety of darolutamide and of stereotactic dose escalated prostate radiotherapy in patients with localised…
- Trial name
- PEACE 7 (NCT06625970)
- Testing
- Darolutamide, Stereotactic Body RadioTherapy (SBRT), ADT (Standard of Care)
- Where
- 6 sites in France, Martinique
- Volunteers
- 700 people
- Sponsor
- UNICANCER
Bronchiectasis
Macrolides in COPD- Bronchiectasis Overlap
To assess safety of long-term macrolide therapy in patients with COPD-bronchiectasis overlap syndrome And evaluate its efficacy in treating COPD-bronchiectasis overlap syndrome regarding change in clinical, functional and…
- Trial name
- NCT04215172
- Testing
- Macrolides
- Volunteers
- 60 people
- Sponsor
- Assiut University
Advanced Solid Tumor, RAS Mutation
Safety and Effectiveness of ABM-168 in Adults with Advanced Solid Tumors.
This is a Phase 1, First-in-Human (FIH), open-label, multicenter, dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of ABM-168 in adult patients…
- Conditions
- Advanced Solid Tumor, RAS Mutation, RAF Mutation, NF1 Mutation
- Trial name
- NCT05831995
- Testing
- ABM-168
- Where
- 6 sites in United States
- Volunteers
- 12 people
- Sponsor
- ABM Therapeutics Corporation
Advanced Biliary Tract Cancer
Safety and Efficacy of Gemcitabine, Toripalimab and Dose- Modified Lenvatinib in Elderly Patients With Advanced Biliary Tract Cancer Intolerant to Conventional Chemotherapy
The goal of this clinical trial is to learn if the regimen of gemcitabine, toripalimab and dose-modified lenvatinib works to treat advanced biliary tract cancer in elderly patients with intolerance to conventional chemotherapy.
- Trial name
- ZSAB-GENTLE (NCT07897565)
- Testing
- gemcitabine, toripalimab, and lenvatinib capsules
- Volunteers
- 39 people
- Sponsor
- Shanghai Zhongshan Hospital
Depression, Fatigue
Depression and Interleukin-6 Production in Patients With Ovarian Epithelial Cancer
RATIONALE: Measuring levels of interleukin-6 and depression may help doctors understand the relationship between interleukin-6 and depression. It may also help the study of cancer in the future.
- Conditions
- Depression, Fatigue, Ovarian Cancer, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT00460200
- Testing
- polymorphism analysis, laboratory biomarker analysis, physiologic testing
- Sponsor
- Jonsson Comprehensive Cancer Center
Trigger Point Pain, Myofascial
Strain Counterstrain Technique and Graston Technqiue on Quadratus Lumborum Trigger Points
Poor body mechanics and posture affects body positioning and stresses quadratus lumborum muscle which ultimately leads to myofascial trigger points in muscle.
- Trial name
- NCT06986707
- Testing
- Strain counterstrain technique, Graston technique
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Childhood Overweight and Obesity
Holbæk Obesity Treatment (HOT) Versus Conventional Obesity Treatment (COT) in Children With Overweight or Obesity.
The HOT versus COT trial aims to compare the effectiveness of two different lifestyle interventions for treatment of childhood overweight and obesity with the purpose of informing future clinical practice guidelines within this…
- Trial name
- HOT vs COT (NCT05038683)
- Testing
- Holbæk Obesity Treatment, Conventional Obesity Treatment
- Where
- 5 sites in Denmark
- Volunteers
- 554 people
- Sponsor
- Holbaek Sygehus
Ovarian Neoplasms Malignant, Sleep Initiation and Maintenance Disorders
Tiaoshen Anti-cancer Protocol and CBT for Insomnia and Survival in Ovarian Cancer
Study Title: A Multicenter, Randomized Controlled Trial of Tiaoshen Anti-cancer Protocol Combined with Cognitive Behavioral Therapy for Insomnia in Improving Sleep and Survival in Ovarian Cancer Patients Purpose: This study aims…
- Conditions
- Ovarian Neoplasms Malignant, Sleep Initiation and Maintenance Disorders, Medicine, Chinese Traditional, Chinese Herbal Medicine
- Trial name
- NCT07550205
- Testing
- Tiaoshen Anti-cancer Granules, Cognitive Behavioral Therapy for Insomnia, Standard First-line Platinum-based Chemotherapy
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Shanghai Municipal Hospital of Traditional Chinese Medicine
Remineralization
Clinical Efficacy of Different Remineralizing Agents in Treatment of White Spot Lesions
The aim of the present study is to evaluate the efficiency of Self-assembling Peptide P11-4, Tricalcium Phosphate Fluoride Varnish, 5% F- and 5% fluoride varnish in remineralization of WSLs in primary dentition among a group of…
- Trial name
- NCT05064137
- Testing
- Monomeric self - assembling peptide P11-4, Tricalcium phosphate fluoride varnish, 5% F-, fluoride varnish (5% sodium fluoride)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Ischemic Stroke
C-arm Cone Beam CTP Guided Cerebrovascular Interventions
The study objective for the Phase 2 of this research is to demonstrate and confirm the substantial time savings that can be obtained using cone beam computed tomography (CB-CT) for both complete image acquisition and rapid image…
- Trial name
- NCT05536895
- Testing
- C-Arm Cone Beam Computed Tomography, Multi-detector Computed Tomography
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
COPD, Inhaler Training
A Comparison of Classic and Virtual Inhaler Training Methods in COPD Patients
According to the World Health Organization data, the third most common cause of death in the world, is COPD , a disease that progresses with exacerbations (1).
- Conditions
- COPD, Inhaler Training, Face-to-face Training, Video-mediated Virtual Training
- Trial name
- NCT05335265
- Testing
- Treatment training
- Where
- 9 sites in Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Ayse Baha
Laser Acupuncture, Pelvic Pain
Effect of Laser Acupuncture on Postnatal Pelvic Girdle Pain
this study was done to evaluate the effect of laser acupuncture on pelvic girdle pain postnatal females' patients.
- Conditions
- Laser Acupuncture, Pelvic Pain, Post Natal
- Trial name
- NCT06715111
- Testing
- Laser acupuncture, conventional pelvic floor exercise
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Stroke, Stroke, Cardiovascular
EMG Control Assistance Virtual Reality Interface Coupled With Cerebellar-iTBS for Arm Recovery After Stroke (ERICA)
The investigators hypothesize that a myoelectric (EMG) controlled virtual reality (VR) interface allows for effective upper limb motor recovery of stroke patients.
- Trial name
- ERICA (NCT06911671)
- Testing
- Virtual Reality Interface + Cerebellar iTBS (c-iTBS), Physical Therapy
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
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