Clinical trials: Conventional therapy
Breast Cancer Female
Robotic Versus Conventional or Endoscopic Nipple Sparing Mastectomy in the Management of Breast Cancer-Prospective Study
This study will prospectively evaluate the surgical outcomes of robotic nipple sparing mastectomy (NSM) compared with endoscopic assisted NSM or conventional NSM in the management of breast cancer.
- Trial name
- RCENSM-P (NCT04037852)
- Testing
- robotic assisted nipple sparing mastectomy, Endoscopic assisted nipple sparing mastectomy, Conventional nipple sparing mastectomy
- Where
- 11 sites in Taiwan
- Volunteers
- 180 people
- Sponsor
- Changhua Christian Hospital
Tourette Syndrome, Deep Brain Stimulation
Multitarget Stereotactic Electrophysiological Recording and Stimulation for Tourette Syndrome
The goal of this clinical trial is to investigate the neural mechanisms underlying Tourette syndrome (TS) and see if personalized deep brain stimulation (DBS) can help reduce tics in TS patients and improve related issues like…
- Trial name
- MASTERS-TS (NCT06889480)
- Testing
- New Target DBS, CM-DBS
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Beijing Tiantan Hospital
Urticaria, Allergy
Adding a Short Burst of Corticosteroid to the Conventional Treatment of H1 Antihistamines in Emergency Department.
A randomized, double-blinded, controlled trial of adding a short burst of corticosteroid to the conventional treatment of H1 antihistamines
- Trial name
- NCT03296358
- Testing
- IV Dexamethasone, Oral prednisolone
- Where
- Thailand
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Hypertension
Cardiovascular Autonomic Control Evaluation Through Cardiac Frequency Variability in Hypertensive Patients
Analyzing cardiovascular evaluation measures in the multidisciplinary and in the conventional treatment of hypertensive patients will provide better parameters for comparing the two approaches.
- Trial name
- NCT02211248
- Testing
- Multidisciplinary assistance, Conventional treatment and follow up
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Chronic Neuropathic Pain
aiTBS and rTMS in Neuropathic Pain and Prediction of Response
This study evaluates the analgesic benefit of two non-invasive brain stimulation techniques: high frequency repetitive transcranial magnetic stimulation (rTMS) and accelerated intermittent theta burst stimulation (aiTBS) …
- Trial name
- TRIPP (NCT07650526)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospital Ambroise Paré Paris
Papillary Thyroid Carcinoma, Lymphatic Metastasis
Comparative Study of Transaxillary Robotic Thyroidectomy With MRND Versus Conventional Open Surgery in N1b PTC
Thyroid cancer is one of the most common malignant tumors in women, ranking seventh in the United States and fourth in China. Papillary thyroid carcinoma is the most common pathological type (about 85% to 90% of thyroid cancers)…
- Trial name
- NCT06623578
- Testing
- robotic-assisted surgery, Open Surgery
- Where
- China
- Volunteers
- 876 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cancer Recurrence, Solid Tumors
Defining the Utility of PET/CT in the Follow-up of Patients With Solid Tumors
This is a comparison, at this VA Hospital,of routine multi-visit and multi-testing for solid tumor recurrence in four tumor groups to a limited scheduled 5 visit history/physical with PET/CT only, over a five year period.
- Trial name
- NCT00954148
- Testing
- PET/CT, NCCN recommendations for solid tumor post treatment
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Dallas VA Medical Center
Pancreatic Cancer
PurIST Classification-Guided Adaptive Neoadjuvant Chemotherapy by RNA Expression Profiling of EUS Aspiration Samples
This is an open-label, phase II study in patients with resectable and borderline resectable pancreatic cancer.
- Trial name
- PANCREAS (NCT04683315)
- Testing
- mFOLFIRINOX Treatment Regimen, Gemcitabine/Nab-paclitaxel Treatment Regimen
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- Medical College of Wisconsin
Undifferentiated Pleomorphic Sarcoma
Focused Ultrasound to Promote Immune Responses for Undifferentiated Pleomorphic Sarcoma
This study is a single site, single-arm, feasibility study to evaluate the safety and efficacy of MRgFUS using the ExAblate 2100 System for the partial ablation of undifferentiated pleomorphic sarcomas.
- Trial name
- HIFU-UPS (NCT04123535)
- Testing
- ExAblate 2000/2100 Magnetic Resonance-guided Focused Ultrasound (MRgFUS)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Matthew Bucknor
Sarcopenia
Clinical Trial of CG-BM1 Allogeneic Human Bone Marrow Mesenchymal Stem Cell Injection in the Treatment of Sarcopenia
1. To evaluate the safety and tolerability of CG-BM1 for the treatment of patients with Sarcopenia. 2. To observe the preliminary effectiveness of CG-BM1 in treating Sarcopenia patients.
- Trial name
- CGBM1-SAR-01 (NCT07865676)
- Testing
- CG-BM1- 5.0 × 10^7 cells, CG-BM1-1.0 × 10^8 cells
- Where
- China
- Volunteers
- 30 people
- Sponsor
- GuangZhou Cellgenes Biotechnology Co., Ltd.
Malnutrition
Effect of Early Nutritional Therapy on Frailty, Functional Outcomes and Recovery of Undernourished Medical Inpatients Trial
The aims of the randomized-controlled, multicenter EFFORT trial are to assess the effects of early nutritional therapy in regard to effectiveness, safety and costs when applied to the heterogenous, polymorbid medical inpatient…
- Trial name
- EFFORT (NCT02517476)
- Testing
- Nutritional therapy
- Where
- Switzerland
- Volunteers
- 2,088 people
- Sponsor
- University Hospital, Basel, Switzerland
Meniscal Tear
Nanoscope Cost Analysis Study
The study is a pilot study designed to generate preliminary data regarding the cost of partial meniscectomy using NanoScope versus conventional arthroscopy in a traditional operating room (OR) setting
- Trial name
- NCT06603740
- Testing
- Arthrex Nanoscope, Conventional Arthroscopy without Arthrex Nanoscope
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Arthrex, Inc.
Pancreas, Cancer
Magnetic Resonance-guided High-intensity Focused Ultrasound Treatment of Locally Advanced Pancreatic Cancer
Patients with unresectable pancreatic cancer in most of cases cannot benefit from percutaneous ablation modalities, due to high risk of procedure-related complications.
- Conditions
- Pancreas, Cancer, Locally Advanced Pancreatic Cancer, Non-invasive Treatment
- Trial name
- NCT01786850
- Testing
- Magnetic Resonance-guided High-intensity Focused Ultrasound (MRgFUS)
- Where
- Italy
- Sponsor
- University of Roma La Sapienza
Oral Mucositis
Efficacy of High-Level Laser Therapy in Managing Oral Mucositis Among Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation
The goal of this clinical trial is to learn if high-level laser therapy can manage oral mucositis in pediatric patients undergoing hematopoietic bone marrow transplantation.
- Trial name
- NCT07436650
- Testing
- high power laser therapy, Basic oral care
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Ain Shams University
Sacroiliac Joint Dysfunction
Effectiveness of McKenzie and Trochanteric Belt With CT Therapy to Reduce Pain and Dysfunction of SI Joint
To determine the effectiveness of McKenzie exercises and trochanteric belt with conventional physical therapy to reduce pain and dysfunction of Sacroiliac joint (SIJ) in pregnant women
- Trial name
- NCT05863390
- Testing
- McKenzie exercise, Trochanteric belt
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Superior University
Sacroiliac Joint Complex, Low Back Pain
Conventional vs Bipolar SIJ RFA for Treatment of Sacroiliac Joint Pain
Specific Aims The sacroiliac joint complex (SIJC) is a diathrodial, synovial joint and posterior ligamentous network that receives both anterior innervation from the lumbosacral plexus as well as posterior sensory innervation via…
- Trial name
- NCT05409443
- Testing
- Nimbus Sacroiliac Joint Radiofrequency Ablation (N-SIJRFA), Conventional Sacroiliac Joint Radiofrequency Ablation (C-SIJRFA)
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Intrahepatic Cholangiocarcinoma (Icc)
Intraarterial Therapies Plus Tislelizumab Plus Lenvatinib Versus Tislelizumab Plus Gemcitabine-Cisplatin in Unresectable Intrahepatic Cholangiocarcinoma
This is a phase III, multicenter, open-label, randomized controlled trial designed to evaluate the efficacy and safety of arterially directed therapy in combination with tislelizumab plus lenvatinib compared with gemcitabine and…
- Trial name
- RAINBOW (NCT07691515)
- Testing
- Gemcitabine, Cisplatin, Tislelizumab
- Where
- 21 sites in China
- Volunteers
- 140 people
- Sponsor
- Zhejiang Cancer Hospital
Physical Activity, PTSD
Tai Chi and Wellness Education for Older Veterans
The primary purpose of this study is to examine physical fitness, PTSD, and satisfaction with a Tai Chi intervention for older (aged 60 and older), sedentary, trauma-exposed veterans, in comparison to a wellness education…
- Conditions
- Physical Activity, PTSD, Satisfaction
- Trial name
- NCT03624868
- Testing
- Tai Chi, Wellness Education
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- VA Boston Healthcare System
Chronic Anal Fissure
Conventional Lateral Internal Sphincterotomy, V-Y Anoplasty and Tailored Lateral Internal Sphincterotomy With V-YF in Treatment of Chronic Anal Fissure(CAF)
The investigators compared conventional lateral internal sphincterotomy (CLIS), V-Y anal flap, and combined tailored lateral internal sphincterotomy with V-Y anal flap (TLIS with V-YF) in a randomized prospective study in…
- Trial name
- CAF (NCT01500889)
- Testing
- Group I: Conventional Lateral internal sphincterotomy:, GroupII: V-Y advancement flap, GroupIII: Tailored LIS with V-Y advancement flap
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Mansoura University
Multiple Myeloma
Human BCMA Targeted T Cells Injection Therapy for BCMA-positive Relapsed/Refractory Multiple Myeloma
To evaluate the safety and efficacy of Human BCMA Targeted T Cells Injection for the treatment of BCMA-positive relapsed/refractory multiple myeloma.
- Trial name
- NCT04003168
- Testing
- Human BCMA targeted T Cells Injection
- Where
- 3 sites in China
- Volunteers
- 18 people
- Sponsor
- Hrain Biotechnology Co., Ltd.
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