Clinical trials: Conventional therapy, completed
Pneumonia Due to COVID-19
Education Impact on Rehabilitation of Hospitalized Patients With Pneumonia and COVID-19
The planned research will enable the assessment of rehabilitation's effects using two pulmonary rehabilitation models: conventional and supplemented with an education program for patients hospitalized due to pneumonia with…
- Trial name
- NCT06522724
- Testing
- Education program, Pulmonary rehabilitation
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- University of Rzeszow
Premature Lungs, Respiratory Distress Syndrome
Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants
This study is being conducted to determine whether prophylactic administration of surfactant by the Less Invasive Surfactant Administration (LISA) method reduces the need for mechanical ventilation in the first 72 hours of life…
- Conditions
- Premature Lungs, Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal
- Trial name
- CaLI (NCT04209946)
- Testing
- Less Invasive Surfactant Administration LISA, Continuous Positive Airway Pressure CPAP
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- Sharp HealthCare
COVID-19, Physical Therapy Modalities
Effectiveness of a Physical Therapy Telerehabilitation Program in Long Post COVID-19 Symptoms in Primary Health Care.
The evolution of Coronavirus disease 2019 (COVID-19) pandemic makes it more necessary the intervention of Primary Health Care Physiotherapy Units in patients with respiratory and/or functional sequelae after suffering from…
- Conditions
- COVID-19, Physical Therapy Modalities, Telerehabilitation, Primary Health Care
- Trial name
- TPhysioCovid (NCT05121688)
- Testing
- Physiotherapy
- Where
- Spain
- Volunteers
- 71 people
- Sponsor
- Universidad Complutense de Madrid
Parkinson Disease, Balance
Effects of Exer Gaming on Balance and Gait in Parkinson's Patients
To compare the effects of exer-gaming with conventional physiotherapy on balance and gait in Parkinson's patients
- Trial name
- NCT05043727
- Testing
- Exer gaming, conventional treatment plan
- Where
- Pakistan
- Volunteers
- 16 people
- Sponsor
- Riphah International University
Frozen Shoulder
Additional Effects of Thoracic Manipulation in Adhesive Capsulitis.
The aim of this study is to measure the additional effects of thoracic manipulation on pain and restricted shoulder mobility and reducing disability in patients with adhesive capsulitis.
- Trial name
- NCT04619173
- Testing
- Thoracic manipulation, Conventional physical therapy Program
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
ITP, Croticosteroid Therapy
Therapy of Adults Affected by Idiopathic Thrombocytopenic Purpura With Dexamethasone
In this prospective, randomized, controlled clinical trial investigators' aim was to compare the efficacy and the adverse effect of 3 therapy cycles of HD-DXM versus conventional treatment with PDN for untreated adult patients…
- Trial name
- NCT02914054
- Testing
- High dose Dexamethasone pulses, Prednisone
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Prostate Cancer
Neoadjuvant CCI-779 Followed By Radical Prostatectomy in Treating Patients With Newly Diagnosed Prostate Cancer Who Have a High Risk of Relapse
RATIONALE: Drugs used in chemotherapy, such as CCI-779, work in different ways to stop tumor cells from dividing so they stop growing or die. Giving CCI-779 before surgery may shrink the tumor so that it can be removed.
- Trial name
- NCT00071968
- Testing
- temsirolimus, conventional surgery, neoadjuvant therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Primary Progressive Aphasia
Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS
This is a double-blind, sham-controlled, crossover study in which subjects with the non-fluent/agrammatic and logopenic variants of primary progressive aphasia (naPPA and lvPPA, respectively) will undergo language testing and…
- Trial name
- NCT04046991
- Testing
- high-definition transcranial direct current stimulation, modified constraint-induced language therapy
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Pennsylvania
Malocclusion, Angle Class I, Malocclusion, Angle Class II
AI-Assisted Versus Conventional Orthodontic Diagnosis and Treatment Planning
This study compared an artificial intelligence-assisted orthodontic diagnostic workflow using WebCeph with a conventional clinician-based workflow.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- AI-OrthoDx (NCT07690774)
- Where
- Yemen
- Volunteers
- 120 people
- Sponsor
- Ben Hafeed Dental Center
Chronic Hepatitis C (Disorder)
Dynamic Changes of Monocytes and NK Cells of CHC Patient Treated by DAAs
Recently,surprisingly and unexpectedly increased aggressiveness and high rates of HCC recurrence (28%(16/58) and 29%(17/59), respectively) have been reported in patients who cleared HCV with DAAs after achieving a complete…
- Trial name
- NCT03063723
- Testing
- Ledipasvir-Sofosbuvir, Daclatasvir-Sofosbuvir
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Brain and Central Nervous System Tumors
Gene Therapy in Treating Patients With Recurrent or Progressive Brain Tumors
RATIONALE: Inserting the gene for p53 into a person's brain cells may improve the body's ability to fight cancer. PURPOSE: Phase I trial to study the effectiveness of p53 gene therapy with SCH-58500 in treating patients who have…
- Trial name
- NCT00004080
- Testing
- recombinant adenovirus-p53 SCH-58500, conventional surgery
- Sponsor
- National Cancer Institute (NCI)
Neonatal Sepsis
Role of Montelukast in Modulation of Response to Sepsis in Preterm Infants
The investigators will conduct this study to explore the role of Montelukast in treatment of neonatal sepsis and whether it has an effect on inflammatory markers, the duration of antibiotic use, or on the patients´ outcome.
- Trial name
- NCT04474327
- Testing
- Montelukast Sodium
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University Children Hospital
Schizophrenia
Fast Titration in the Treatment of Schizophrenia, Taiwan
Assess the efficacy of a fast titration of quetiapine to the current titration approved by the regulatory authorities. PLEASE NOTE: Seroquel SR and Seroquel XR refer to the same formulation.
- Trial name
- NCT00304473
- Testing
- Quetiapine fumarate
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- AstraZeneca
Dry Eye Disease
A Study to Evaluate 0.003% AR-15512 Safety and Drop Attributes
The purpose of this study is to evaluate the percentage of ocular adverse events reported in subjects with dry eye disease (DED) between the intervention arm (0.003% AR-15512) and control arm (REFRESH® Classic).
- Trial name
- NCT06660290
- Testing
- 0.003% AR-15512 ophthalmic solution, Artificial tears
- Where
- 6 sites in United States
- Volunteers
- 55 people
- Sponsor
- Alcon Research
Chronic Cor Pulmonale
The Effect of External Diaphragmatic Pacemaker on the Patients With Chronic Cor Pulmonale
This study evaluates the effect of external diaphragmatic pacemaker on the patients with chronic cor pulmonale. Half of participants will receive external diaphragmatic pacemaker, while the other half will receive routine therapy.
- Trial name
- NCT02976324
- Testing
- external diaphragmatic pacemaker group
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhang Xiangyu
Shoulder Impingement
Efficiency of Hypervolt Device Application in the Treatment of Shoulder Impingement Syndrome
The aim of this study is to compare the effects of exercise and Hypervolt Device on pain, muscle strength and normal joint movement in the treatment of shoulder impingement syndrome.
- Trial name
- NCT06006351
- Testing
- Physiotherapy, Hypervolt Device
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Uskudar University
Stroke
Repetitive Transcranial Magnetic Stimulation Use in Acute Stroke
When a certain area of the brain is injured, like in stroke, several events occur. One side of the body may become weak. This weakness is called hemiparesis and it may create difficulty in performing tasks like writing, eating…
- Trial name
- NCT01922986
- Testing
- active rTMS, conventional stroke therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Minnesota
Prostate Cancer
Diindolylmethane in Treating Patients With Stage I or Stage II Prostate Cancer Undergoing Radical Prostatectomy
RATIONALE: The use of diindolylmethane, a substance found in cruciferous vegetables, may slow the growth of tumor cells. PURPOSE: This phase II trial is studying how well diindolylmethane works in treating patients with stage I…
- Trial name
- NCT00888654
- Testing
- B-Dim, Radical Prosatectomy
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Clinical Syndrome
Oral Ivermectin for Chikungunya Viral Infection
Chikungunya viral infection (CVI) is a mosquito-borne infection, caused by chikungunya virus (CHIKV), an alphavirus, belonging to the family Togaviridae.
- Trial name
- NCT06259383
- Testing
- Ivermectin
- Where
- Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Neurofibromatosis Type 1, Sarcoma
Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors
RATIONALE: Drugs used in chemotherapy, such as doxorubicin, ifosfamide, and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00304083
- Testing
- filgrastim, doxorubicin hydrochloride, etoposide
- Where
- 17 sites in United States
- Volunteers
- 48 people
- Sponsor
- Sarcoma Alliance for Research through Collaboration
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