Clinical trials: Conventional therapy, completed
Atrial Fibrillation, Heart Failure
Catheter Ablation vs. Standard Conventional Treatment in Patients With LV Dysfunction and AF
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. The incidence and prevalence of AF increase exponentially with increasing age and AF is associated with higher mortality, more frequent…
- Trial name
- CASTLE-AF (NCT00643188)
- Testing
- Radiofrequency ablation, Conventional treatment
- Where
- 32 sites in Australia, Austria and 6 more
- Volunteers
- 398 people
- Sponsor
- Biotronik SE & Co. KG
Laminectomy
Neural Mobilization and Conventional Physical Therapy After Laminectomy
This study was conducted to evaluate the effect of addition of neural mobilization to a standard post-operative physical therapy program in patients with lumbar laminectomy.
- Trial name
- NCT04498338
- Testing
- Neural mobilization combined with conventional physical therapy program, Conventional physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Neuralgia,Postherpetic
Pulsed Electromagnetic Field Therapy Versus Transcutaneous Electrical Nerve Stimulation in on Post-herpetic Neuralgia of the Sciatic Nerve
Background and purpose: Post-herpetic neuralgia (PHN) is the most frequent chronic complication of herpes zoster, resulting in post- infectious severe neuropathic pain.
- Trial name
- NCT04488835
- Testing
- Electromagnetic field therapy and transcutaneous electrical nerve stimulation
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Musculoskeletal Diseases
Pilates Mat Versus Cervical Stabilization Exercises on Balance in Young Adults With Forward Head Posture
see if there will be no statistical significant difference between the effects of Pilates mat versus cervical stabilization exercises on dynamic balance in young adults with forward head posture.
- Trial name
- FHP (NCT05068817)
- Testing
- Pilates mat exercises, cervical stabilization exercises, conventional physiotherapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Non-Alcoholic Fatty Liver Disease
High Oral Loading Dose of Cholecalciferol in Non-Alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder with high prevalence in patients suffering from chronic liver diseases [1].
- Trial name
- NCT05578404
- Testing
- Cholecalciferol
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Type 1 Diabetes
Multicenter Assessment of the PDA-FIT System in Type 1 Diabetic Patients
TELEDIAB-1 is a national, multicenter, controlled, randomised trial. The Primary objective of the TELEDIAB-1 study is to demonstrate that the PDA-FIT system (PDA-Phone and/or telemonitoring) is able to improve metabolic control…
- Trial name
- TELEDIAB-1 (NCT00629304)
- Testing
- VISITS + PDA-FIT system, PDA-FIT System + telephone follow-up
- Where
- 18 sites in France
- Volunteers
- 180 people
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Obesity
Effect of Intermittent Versus Continuous Energy Restriction on Compensatory Mechanisms Activated During Weight Reduction
Obesity has become a global epidemic with huge public health implications. Although clinical significant weight loss can be achieved by a combination of diet and behavioral modification, strong metabolic adaptations, with…
- Trial name
- NCT02169778
- Testing
- Intermittent energy restricted diet, Continuous energy restricted diet
- Where
- Norway
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Cerebral Palsy
Comparison of Efficacy of Sensory Integration Therapy in Children With Cerebral Palsy
In this we are comparing efficacy of sensory integration therapy as an adjunct to standard care with standard care alone in improving gross motor skills in cerebral palsy children with sensory processing abnormalities.Existing…
- Trial name
- NCT03888508
- Testing
- SIT
- Where
- India
- Volunteers
- 30 people
- Sponsor
- All India Institute of Medical Sciences
Soft Tissue Sarcoma
Study in Patients With Advanced Soft Tissue Sarcoma (STS) After Failure of Anthracyclines and/or Ifosfamide
This is an observational, non-randomized, open label, multicenter, phase IV study, which aims to reflect a real-life practice routinely used for the management of advanced soft tissue sarcoma after failure of anthracyclines…
- Trial name
- NCT01299506
- Where
- 5 sites in Netherlands
- Volunteers
- 102 people
- Sponsor
- PharmaMar
Adenoma Colon, Serrated Polyp
Cold EMR Vs Standard EMR for the Treatment of Large Nonpedunculated Homogeneous Colorectal Lesions
This study compares the effectiveness in complete resection (absence of recurrence at 6 months) the two different techniques for performing endoscopic mucosal resection (EMR) of nonpedunculated homogeneous colorectal lesions >20mm
- Conditions
- Adenoma Colon, Serrated Polyp, Serrated Adenoma, Colorectal Neoplasms
- Trial name
- NCT04418843
- Testing
- Standard Endoscopic Mucosal Resection, Cold Snare Endoscopic Mucosal Resection
- Where
- Spain
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Oscar Nogales
Gestational Diabetes Mellitus in Pregnancy
Carbohydrates Distribution in Pregnancy Study
Hypothesis: Patients with Gestational Diabetes Mellitus (GDM) have a high risk to develop complications during pregnancy, puerperium and in the newborn.
- Trial name
- CHiPS (NCT03378908)
- Testing
- Intervention Treatment
- Where
- 2 sites in Spain
- Volunteers
- 10 people
- Sponsor
- Germans Trias i Pujol Hospital
Down Syndrome
Effects of Bin Therapy on Finger Gnosia And Fine Motor Skill
Down syndrome is a hereditary disorder resulting from the occurrence of an additional copy of chromosome 21, resulting in discernible variations in cognitive and physical characteristics.
- Trial name
- NCT06576206
- Testing
- Bin therapy and finger gnosia, conventional therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
HER-2 Gene Amplification
A Study of MM-111 in Combination With Multiple Treatments in Patients With HER2 Positive Cancer
This study is an open-label, dose-escalation study of MM-111 with five different combination treatments with the main goal of determining the safety of MM-111 with each combination.
- Trial name
- NCT01304784
- Testing
- Cisplatin, Capecitabine, Trastuzumab and MM-111, Lapatinib +/- Trastuzumab and MM-111, Paclitaxel, Trastuzumab and MM-111
- Where
- 15 sites in United States
- Volunteers
- 100 people
- Sponsor
- Merrimack Pharmaceuticals
Critical Illness, Intensive Care
Registration Enabling Study of the Safety and Efficacy of the Use of the Navigator Circulatory Management System
A multicentre, open, RCT to assess the safety and efficacy of the Navigator Guided Circulatory Management System versus conventional care in post-operative cardiac surgery patients.
- Trial name
- NAV-1 (NCT00468247)
- Testing
- Navigator, Conventional care
- Where
- 7 sites in Australia
- Volunteers
- 112 people
- Sponsor
- Applied Physiology Pty Ltd
Post-traumatic Stress Disorder, Adjustment Disorders
Pivotal Trial of SAT-014 for Trauma and Stressor-Related Disorder Symptoms
The aim of this study is to evaluate the efficacy of SAt-014, a software as a medical device (SaMD), in alleviating symptoms of trauma and stressor-related disorders in patients with post-traumatic stress disorder (PTSD) or…
- Trial name
- NCT06734858
- Testing
- SAT014, Control
- Where
- 5 sites in South Korea
- Volunteers
- 110 people
- Sponsor
- S-Alpha Therapeutics, Inc.
Osteoarthritis, Knee
Extracorporeal Shock Wave Therapy in Osteoarthritis
The present study has examined the effectiveness of extracorporeal shock wave therapy along with conventional physical therapy on functional ability in grade IV knee osteoarthritis.
- Trial name
- NCT06181955
- Testing
- Extracorporeal Shock Wave Therapy, conventional physical therapy
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- King Saud University
Pain, Postoperative
Micro-surgical Treatment of Gummy Smile
Compare pain response following microsurgical conventional flap approach using Piezosurgery versus flapless approach for esthetic crown lengthening in management of patients with short clinical crowns in the upper anterior region.
- Trial name
- NCT04401826
- Testing
- Tunneling micro-surgical crown lengthening approach using piezo-surgery, Micro-surgical crown lengthening approach using Piezosurgery
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma
Chemoembolization With or Without Sorafenib Tosylate in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
This randomized phase III trial studies chemoembolization and sorafenib tosylate to see how well they work compared with chemoembolization alone in treating patients with liver cancer that cannot be removed by surgery.
- Trial name
- NCT01004978
- Testing
- Cisplatin, Computed Tomography, Doxorubicin Hydrochloride
- Where
- 281 sites in United States
- Volunteers
- 235 people
- Sponsor
- National Cancer Institute (NCI)
Emotion Regulation
VR-CBT With Inuit in Quebec
The study design is a two-arm randomized controlled pilot trial. The investigators will recruit Inuit in Montreal and randomly assign them to two treatment groups (n=20 each).
- Trial name
- NCT05631743
- Testing
- VR-CBT, Self-management
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Douglas Mental Health University Institute
Constipation
The Efficacy and Safety Study of Electro-acupuncture for Severe Chronic Functional Constipation
The main purpose of this study is to evaluate efficacy of electro-acupuncture for severe functional constipation compared with sham acupuncture, used as placebo; the secondary purpose is to evaluate the safety and post-treatment…
- Trial name
- NCT01726504
- Testing
- electro-acupuncture
- Where
- China
- Volunteers
- 1,075 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
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