Clinical trials: Conventional therapy
Autism, Developmental Delay Disorders
Project EARLY: Engagement, Assessment, Referral, & Linkage for Young Children
Emerging evidence demonstrates that Autism Spectrum Disorder (ASD) can be reliably diagnosed by age two, and that early identification and intervention can improve outcomes.
- Trial name
- NCT02359084
- Testing
- Family Navigation, Conventional Care Management
- Where
- 10 sites in United States
- Volunteers
- 340 people
- Sponsor
- Boston University
Coronary Artery Disease, Heart Failure
Stress Echo 2030: the Novel ABCDE-(FGLPR) Protocol to Define the Future of Imaging
With stress echo (SE) 2020 study, a new standard of practice in stress imaging was developed and disseminated: the ABCDE protocol for functional testing within and beyond CAD.
- Conditions
- Coronary Artery Disease, Heart Failure, Hypertrophic Cardiomyopathy, Congenital Heart Disease
- Trial name
- SE2030 (NCT05081115)
- Testing
- ABCDE-Stress Echo, SE diastolic assessment, SE Right ventricular function assessment
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- Fatebenefratelli Hospital
Ventricular Tachycardia
Catheter Ablation Versus Radio-Ablation for Ventricular Tachycardia: a Randomized Controlled Trial
This study compares two arms - the current standard of care catheter ablation for Ventricular Tachycardia compared to stereotactic radiotherapy to non-invasively ablate ventricular tachycardia using a novel non-invasive ECG based…
- Trial name
- CARA-VT RCT (NCT05047198)
- Testing
- Control - Catheter Ablation for VT, Treatment - Non-Invasive Radio Ablation for VT
- Where
- Canada
- Volunteers
- 244 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Peri-implant Mucositis
Incidence of Peri-implant Mucositis in Patients With Treated Periodontitis
the objective of this study is to determine the incidence of peri-implant mucositis in patients with treated periodontitis and enrolled in periodontal maintenance and to evaluate the associated risk indicators.
- Trial name
- PiM_Inc (NCT05356806)
- Testing
- Supportive periodontal and periimplant care
- Where
- Spain
- Volunteers
- 277 people
- Sponsor
- Universidad Complutense de Madrid
Anxiety, Signs and Symptoms
Effectiveness of a Music Therapy Intervention in Cancer Patients Undergoing Active Treatment at the Jaén University Hospital: a Non-randomized Controlled Trial.
A cancer diagnosis and its clinical progression can cause patients physical, psychological, emotional, social, and spiritual distress.
- Conditions
- Anxiety, Signs and Symptoms, Oncologic Complications
- Trial name
- ECMONC (NCT07886658)
- Testing
- Music Therapy
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Jaén
Carpal Tunnel Syndrome
Investigation of the Efficiency of Radial Extracorporeal Shock Wave Therapy at Different Pulses in Carpal Tunnel Syndrome
Different parameters have been used in studies investigating the efficacy of extracorporeal shock wave therapy in the treatment of carpal tunnel syndrome.
- Trial name
- NCT06321276
- Testing
- extracorporeal shockwave therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Ahi Evran University Education and Research Hospital
SAPHO Syndrome
Study of the Efficacy and Safety of Etanercept Treatment in Patients With SAPHO Syndrome
The study includes adult patients with SAPHO syndrome (ORPHA: 793), meeting the modified classification criteria according to Kahn (2003), with the ineffectiveness of standard treatment (patient's global assessment of the disease…
- Trial name
- SAPHO (NCT06011889)
- Testing
- Etanercept
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Low Back Pain, Chronic Low-back Pain
Effect of Diaphragm Manual Therapy With Conventional Physical Therapy in Chronic Non-Specific Low Back Pain Patients
A randomized single-blind clinical study will be performed. A sample size of 34 patients including only male gender, will be taken from various clinical settings of Faisalabad.
- Trial name
- NCT05299216
- Testing
- Manual Diaphragm Technique, Conventional Physical Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- University of Faisalabad
Sacroiliac Joint Dysfunction
Gluteus Maximus Versus Gluteus Medius Strength On Back Muscles Performance In Patients With Sacroiliac Dysfunction
This study will be conducted to compare between the effect of glutes maximus and glutes medius muscles strength on back muscle performance in patients with Sacroiliac joint dysfunction.
- Trial name
- NCT05809206
- Testing
- Glutes maximus strength protocol, Gluteus medius strength program, Corrective Exercises
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Skeletal Class II Malocclusion
Modified Versus Clear Twin Block for Skeletal Class II Malocclusion
This study aims to evaluate the effectiveness of a modified Twin Block appliance compared to a conventional clear Twin Block appliance in the treatment of skeletal Class II malocclusion caused by mandibular retrusion in growing…
- Trial name
- MTB-CTB (NCT07608406)
- Testing
- Modified Twin Block Appliance, Conventional Clear Twin Block Appliance
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- University of Aleppo
Dental Anxiety, Pain Management
Impact of Local Anesthesia Techniques on Children's Dental Treatment Experience
compare the effectiveness of several local anesthetic delivery systems in managing pain, anxiety, behavior, and vital signs among pediatric dental patients.
- Conditions
- Dental Anxiety, Pain Management, Pediatric Dentistry
- Trial name
- NCT07106138
- Testing
- Conventional syringe injection, Star Pen, Comfort-In
- Where
- Syria
- Volunteers
- 112 people
- Sponsor
- Latakia University
Constipation
Washed Microbiota Transplantation for Chronic Constipation in Adults
This is a single-center, randomized, double-blind, placebo-controlled, dose-exploring clinical study to explore the safety and efficacy of washed microbiota transplantation (WMT) for patients with chronic constipation.
- Trial name
- NCT06106685
- Testing
- High-dose washed microbiota suspension, Low-dose washed microbiota suspension
- Where
- 2 sites in China
- Volunteers
- 18 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Pediatric Dentistry
Comparing Minimally Invasive Techniques Used In Treatment Of Carious Primary Molars In Children
Dental caries is a natural process by which bacteria in the biofilm causes fluctuations in the pH, which leads to enamel erosion and result in visible lesions.
- Trial name
- NCT06592885
- Testing
- Atraumatic Restorative Treatment in treatment of carious primary molars, Hall Technique in treatment of carious primary molars
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Neurologic Diseases, Arthropathy of Knee
Experience of Use and Biopsychosocial Effects of Robotic and Virtual Reality Devices in Neuromotor Rehabilitation
The implementation of virtual reality (VR) and robotic devices in neuromotor rehabilitation has so far provided promising evidence in terms of efficacy throughout different clinical populations.
- Conditions
- Neurologic Diseases, Arthropathy of Knee, Arthropathy of Hip
- Trial name
- NCT05399043
- Testing
- Multidisciplinary Conventional Neuromotor Rehabilitation, Technology-based Rehabilitation
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Diabetes Mellitus, Type 2
Evaluation of Efficacy and Safety of Insulin Glargine Injected by Needle-free Jet Syringe
Using CGMS to compare the blood sugar improvement and patient sensibility of insulin glargine injected with needle-free jet injector and conventional insulin pen
- Trial name
- NCT04093284
- Testing
- The needle-free jet injector
- Volunteers
- 60 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Class II Malocclusion
Comparative Effect of Conventional and 3D-printed Twin Block Appliances on Soft Tissue Changes
: To evaluate the effectiveness of functional device treatment using both 3D-printed and conventional Twin Block appliances on soft tissue changes during growth modification in Class II malocclusion.
- Trial name
- Clinic Radiogr (NCT07795138)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Peri-Implantitis and Peri-implant Mucositis
SPiT-frequency II_Peri-implantitis
This is an interventional clinical study on the peri-implant treatment necessary to improve the clinical conditions surrounding dental implants registered with peri-implant inflammation.
- Trial name
- NCT06737315
- Testing
- Submocosal instrumentation using a ultrasonic device (PEEK). Submucosal cleaning
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University of Oslo
Spinal Metastases, Bone Metastases
Randomized Trial Comparing Conventional Radiotherapy With Stereotactic Radiotherapy in Patients With Bone Metastases - VERTICAL Study
The purpose of the study is to investigate effectiveness of stereotactic body radiotherapy in patients with bone metastatic disease.
- Trial name
- VERTICAL (NCT02364115)
- Testing
- Stereotactic Body Radiotherapy
- Where
- Netherlands
- Volunteers
- 110 people
- Sponsor
- UMC Utrecht
Graves Disease
Effective Iodide Therapy for Untreated Patients With Graves' Hyperthyroidism Avoiding Thionamide Drugs With Many Side Effects
As the drug treatment of Graves' hyperthyroidism, Plummer reported the effectiveness of excess iodide in 1923 and iodide was used as the therapy for Graves' hyperthyroidism starting from the 1930s.
- Trial name
- NCT04686006
- Testing
- Potassium Iodide
- Volunteers
- 504 people
- Sponsor
- Kyushu University
Non Epileptic Seizures, Functional Neurological Symptom Disorder
Ketogenic Diet Effects on the Frequency of Non Epileptic Seizures
The objective of this study is to determine the effects of the ketogenic diet on the frequency of non-epileptic seizures in patients with functional neurological symptoms disorder compared to a healthy diet.
- Conditions
- Non Epileptic Seizures, Functional Neurological Symptom Disorder, Conversion Disorder, Ketogenic Dieting
- Trial name
- NCT05219006
- Testing
- ketogenic dieting, healthy dieting
- Where
- Mexico
- Volunteers
- 17 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
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