Clinical trials: Conventional therapy
Osteoarthritis
Complex Āyurvedic Treatment in Osteoarthritis of the Knee Compared to Standard Care.
The aim of this study is to evaluate the effectiveness of a complex āyurvedic diagnosis and treatment compared to conventional standard care in patients with OA of the knee.
- Trial name
- CARAKA (NCT01225133)
- Testing
- Complex Ayurvedic Treatment, Conventional Care
- Where
- 2 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Charite University, Berlin, Germany
Covid-19
Ayurveda as Prophylaxis for Suspected COVID-19 Patients
Despite worldwide efforts to contain, manage and treat Covid-19, the pandemic is continuing to spread. This calls for an urgent clinically-proven prophylaxis and therapeutic strategy.
- Trial name
- NCT04395976
- Testing
- Ayurveda
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- British Ayurvedic Medical Council
Severe Asthma, Allergy and Asthma
Multi-omics in Severe Asthma From Olive Pollen Allergy
Patients with severe olive pollen allergy exhibit characteristic sensitization profiles, marked by strong recognition of minor allergens like Ole e 7, and, more importantly, show poor clinical responses to pharmacological…
- Conditions
- Severe Asthma, Allergy and Asthma, Pollen; Allergy, Asthma
- Trial name
- DUPITEOLE (NCT07721376)
- Where
- Spain
- Volunteers
- 18 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Ameloblastoma, BRAF V600E Mutation Positive
Clinical Study of Neoadjuvant Targeted Therapy for Ameloblastoma
This study aims to evaluate the tumor shrinkage effect of preoperative targeted induction therapy with dabrafenib and trametinib in patients with conventional ameloblastoma harboring the BRAF V600E mutation.
- Trial name
- NETCAM (NCT06653517)
- Testing
- Dabrafenib, Trametinib
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Sarcoma
Valganciclovir in Treating Patients With Classic Non-HIV-Associated Kaposi's Sarcoma
RATIONALE: Herpesvirus is found in the lesions of most patients with Kaposi's sarcoma, and may have a role in causing Kaposi's sarcoma.
- Trial name
- NCT00096538
- Testing
- valganciclovir
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Diabetes Mellitus, Type 2
The Effect of Music Therapy on Pain and Anxiety
The effect of music therapy on pain and anxiety will be evaluated in individuals with diabetes who start insulin therapy for the first time. Music will be played during the training.
- Trial name
- NCT04971655
- Testing
- Music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Abant Izzet Baysal University
Subacute Stroke, Stroke
The Effect of Robotic Rehabilitation in Stroke Patients
The goal of this randomized controlled clinical trial is to investigate the efficacy and safety of adding robot-assisted upper extremity therapy to conventional rehabilitation in patients with early subacute stroke.The primary…
- Conditions
- Subacute Stroke, Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- Hemiplegia (NCT07834255)
- Testing
- Robot-Assisted Upper Extremity Therapy, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Lokman Hekim University
Coronary Artery Bypass Graft Triple Vessel, Blood Coagulation Disorders
Goal-orientated Therapy of Perioperative Disturbance in Hemostasis in Cardiac Surgery
Aim of this study is to investigate whether patients preoperatively treated with acetylsalicylic acid and/or clopidogrel have fewer perioperative bleeding and lower amounts of blood substitution when managed by ROTEM (whole blood…
- Trial name
- NCT00516126
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Basel, Switzerland
Necrotic Pulp, Regenerative Endodontic Procedures
Maximum Occlusal Bite Force of Necrotic Permanent Teeth Treated by Regenerative Technique: Randomized Clinical Trial
Further investigation is warranted to ascertain whether the regaining of sensibility and nerve function in regenerated teeth leads to the re-establishment of the proprioceptive protective mechanism inherent in vital teeth.
- Conditions
- Necrotic Pulp, Regenerative Endodontic Procedures, Bite Force
- Trial name
- NCT06934317
- Testing
- measurement of maximum bite force using bite fork, conventional root canal treatment, pulp revascularization by induced bleeding
- Where
- Jordan
- Volunteers
- 40 people
- Sponsor
- Lama Awawdeh
Dental Caries
Dental Caries Management by Risk Assessment: Identification and Treatment of Risk Factors Among (IDF) Personnel
Our study is designed as an interventional prospective longitudinal study which examines the Israeli defense force personnel. The population of our study is composed out of the IDF personnel which will be randomly be subdivided…
- Trial name
- CAMBRA (NCT01142440)
- Testing
- behavioral intervention
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Liver Cirrhosis
Stem Cell Transplantation in Cirrhotic Patients
Chronic liver disease end by liver cirrhosis and increases the risk of cancer development. Chronic liver disease in Egypt is recognized as a serious health problem affecting greater than (20 %) of the population, where the main…
- Trial name
- NCT02943889
- Testing
- Mesenchymal stem cell transplantation
- Volunteers
- 40 people
- Sponsor
- Assiut University
Low Back Pain
Short Foot Exercises and Anti-pronation Taping on Low Back Pain Associated With Hyper Pronation
The aim of this randomized clinical trial is to find the comparison of Short foot exercises and anti-pronation taping on low back pain associated with hyper pronation on reducing back pain improving range of motion of foot, back…
- Trial name
- NCT06584721
- Testing
- Anti-pronation taping (Low dye taping) + Conventional therapy, Short Foot Exercises + Conventional PT
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Pain, Chronic, Shoulder Pain
Pulsed Radiofrequency to the Suprascapular Nerve
Regardless of the etiology, chronic shoulder pain is a distressing condition that affects daily life and is among the first common reasons for musculoskeletal system problems when admitting to clinics.
- Trial name
- NCT06527014
- Testing
- Pulse Radiofrequency to the suprascapular nerve
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Ankara City Hospital Bilkent
Relapsed or Refractory Anaplastic Large Cell Lymphoma & Hodgkin Lymphoma
Registry of BrentuximabVedotinin Patients With R/R Anaplastic Large Cell Lymphoma or Classical HL
In case of relapsed or refractory ALK-negative ALCL patients, high-dosage chemotherapy/ stem cell transplantation is a universal salvage option for patients with sensitivity to anti-cancer treatment and a relatively successful…
- Trial name
- BRAVO (NCT03766516)
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Thoracic Spine Neoplasm
Safety of MRI Compatible Hardware for MRI-based Image Guidance During Spine Surgery
This trial investigates the safety and accuracy of using 2 pieces of hardware (a clamp and a needle) that are able to be used with magnetic resonance imaging (MRI) during spinal surgery.
- Trial name
- NCT04563806
- Testing
- Magnetic Resonance Imaging, Therapeutic Conventional Surgery
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- M.D. Anderson Cancer Center
Atrial Fibrillation, Obesity
SORT - AF Supervised Obesity Reduction Trial for AF Ablation Patients
Study hypothesis: Weight reduction in obese patients with atrial fibrillation. Obese patients benefit from an obesity treatment after atrial fibrillation ablation. Study design: A prospective randomized, open-label clinical trial.
- Conditions
- Atrial Fibrillation, Obesity, Sleep Apnea
- Trial name
- SORT-AF (NCT02064114)
- Testing
- Intervention group, control group
- Where
- 4 sites in Germany
- Volunteers
- 142 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Hypoxic Ischemic Encephalopathy
Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Hypoxic Ischemic Encephalopathy
This study is to evaluate the safety and efficacy of Umbilical Cord Derived Mesenchymal Stem Cells transplantation in hypoxic ischemic encephalopathy.
- Trial name
- NCT01962233
- Testing
- mesenchymal stem cells
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Hebei Medical University
Sepsis
Clinical Study Evaluating the Efficacy and Safety of Fenofibrates Versus Silymarin in Adult Patients With Sepsis
Sepsis is a life-threatening condition defined by organ dysfunction resulting from the body's dysregulated response to an infection (1).
- Trial name
- NCT07572552
- Testing
- Fenofibrate, Silymarin
- Volunteers
- 66 people
- Sponsor
- Tanta University
Low Back Pain
Reformer Pilates vs Conventional Physiotherapy in Chronic Low Back Pain
Non-specific chronic low back pain is one of the most prevalent musculoskeletal disorders worldwide and is associated with functional limitations and reduced quality of life.
- Trial name
- NCT07543952
- Testing
- reformer Pilates exercises, conventional physiotherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Osteoarthritis Knees Both, Pain, Chronic
Investigation of the Effectiveness of a Structured Squat-based Program in Knee Osteoarthritis Rehabilitation
The main purpose of the study is to examine the effect of squat-based exercise approach in individuals with knee osteoarthritis.
- Conditions
- Osteoarthritis Knees Both, Pain, Chronic, Walking, Difficulty
- Trial name
- NCT04588558
- Testing
- Flywheel exercise, Home exercise, Electrotherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul Medipol University Hospital
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