Clinical trials: Conventional therapy
Keratoconus
The Additional Role of Supplemental Oxygen Therapy in Accelerated Corneal Collagen Cross-linking in Progressive Keratoconus. A Randomized Clinical Trial
It is aimed to investigate the role of supplemental systemic oxygen therapy during accelerated corneal collagen crosslinking (CXL).
- Trial name
- NCT04343326
- Testing
- perform corneal collagen cross linking accelerated and delivery of systemic oxygen, perform corneal collagen cross linking accelerated and without additional oxygen therapy, perform Conventiona corneal collagen cross linking
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Prostate Cancer
SBRT vs. Conventional Fractionation With HDR Boost for Prostate Cancer
Random assignment between SBRT and conventionally fractionated boost following HDR brachytherapy for prostate cancer.
- Trial name
- SHARP (NCT04861415)
- Testing
- Sterotactic Body Radiotherapy, Conventionally Fractionated Radiation
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Dr. Gerard Morton
Peripheral Nerve Injuries
Performance Study of an Artificial Nerve Guide (Reaxon® Nerve Guide) to Treat Digital Nerve Lesions
The purpose of this clinical investigation is to confirm the medium- and long-term safety and performance of the chitosan-based nerve guide (Reaxon® Nerve Guide) in comparison to an autologous nerve graft to bridge nerve defects…
- Trial name
- NCT02459015
- Testing
- Implantation
- Where
- 4 sites in Germany
- Volunteers
- 46 people
- Sponsor
- Medovent GmbH
Depression, Dysthymia
Cognitive Behavioral Therapy (REBT/CBT) Evaluation for Dysthymia in the Practice of Clinical Social Work at Primary Care
Introduction: Minor psychiatric disorders are important in primary care, because of its high prevalence and consumption of healthcare resources generated.
- Conditions
- Depression, Dysthymia, Ambulatory Health Services
- Trial name
- NCT02112708
- Testing
- Rational-Emotive-Behavioral Therapy, Control Group usual care
- Where
- Spain
- Volunteers
- 129 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cervicogenic Headache
Comparative Effects Of Eye-Cervical Re-Education Exercises And Pressure Biofeedback Training Of Deep Cervical Flexors In Cervicogenic Headache
Cervicogenic headache (CGH) is a secondary headache that originates from dysfunction in the upper cervical spine, particularly the atlanto-occipital and C1-C3 segments, and is perceived in one or more regions of the head and/or…
- Trial name
- NCT07526025
- Testing
- Eye cervical re-education exercises, Pressure biofeedback training group
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Foundation University Islamabad
Mother Fetus Relations, Health Behavior
Examining the Effect of Breastfeeding Education Given to Mothers Based on Postpartum Awareness Practices on Breast Milk and Cortisol Hormone at the Newborn Circadian Level
In addition to being an easily accessible and ready-made food for babies in the first years of life, breast milk plays a major role in transmitting information about the time of day to newborn babies and therefore in the…
- Trial name
- NCT06240676
- Testing
- AWARENESS-BASED COGNITIVE THERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Kafkas University
Cerebral Palsy (CP)
Effect of Aquatic Therapy Program on Balance in Children With Spastic Diplegic Cerebral Palsy
1. Evaluate the effect of a structured aquatic therapy programme on static balance in children with spastic diplegic cerebral palsy. 2. Assess the effect of the same programme on dynamic balance in this patient population. 3.
- Trial name
- NCT07669350
- Testing
- aquatic therapy, land exercise program
- Volunteers
- 50 people
- Sponsor
- Delta University for Science and Technology
Low Back Pain
Therapeutic Exercise and Education for Low Back Pain
This study will evaluate a new treatment program for patients with ongoing or long-term low back pain who receive care at primary care physiotherapy units.
- Trial name
- NCT07713082
- Testing
- Therapeutic Exercise, Education on the self-management of low back pain, Usual Care
- Where
- Spain
- Volunteers
- 132 people
- Sponsor
- University of Valladolid
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency
The general aim of this study in adult patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) and severe renal insufficiency is to assess the safety and the efficacy of sirolimus (SRL) in slowing renal function…
- Trial name
- SIRENA-II (NCT01223755)
- Testing
- Sirolimus, conventional therapy
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Retinopathy of Prematurity (ROP)
Aflibercept for Retinopathy of Prematurity - Intravitreal Injection Versus Laser Therapy
The purpose of this study is to demonstrate how well aflibercept works in babies with ROP, comparing it with laser therapy. The study also has the objective to demonstrate how safe aflibercept is when used in babies, and describe…
- Trial name
- FIREFLEYE (NCT04004208)
- Testing
- Eylea (Aflibercept, BAY86-5321), Laser photocoagulation
- Where
- 90 sites in Argentina, Austria and 25 more
- Volunteers
- 113 people
- Sponsor
- Bayer
Gastrectomy, Laparoscopy
A Clinical Study for Comparison of the Effects Between Gasless Laparoscopy and Conventional Laparoscopy for Distal Gastric Cancer
The aim of this trial is to confirm the non-inferiority of Gasless laparoscopy-assisted distal D2 radical gastrectomy to the conventional laparoscopy-assisted distal D2 radical gastrectomy for the treatment of advanced gastric…
- Trial name
- NCT05495217
- Testing
- Conventional Laparoscopy, Gasless Laparoscopy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xue Yingwei
Deafness; Perception
Programming Cochlear Implant With Artificial Intelligence
This thesis project proposes to investigate the "state of the art" of the programming of the cochlear implant. In the center of audiophonologie Brussels, the classic 'manual programming' has been in use over 20 years and also the…
- Trial name
- CI_AI (NCT03700268)
- Testing
- Manual intervention to programme Cochlear Implant electrodes
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Hypoxia
High Flow Nasal OXygen Therapy in High Risk Patients of Hypoxia Undergoing Diagnostic BRONCHOscopy
The purpose of this study is to determine the efficacy and safety of nasal high flow oxygen therapy during diagnostic bronchoscopy.
- Trial name
- HFNOT (NCT01650974)
- Testing
- HFNOT
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Seoul National University Hospital
Chronic Myelocytic Leukemia
Evaluating True PCR-negative Rate of Frontline Dasatinib in Early Chronic Phase CML for Therapeutic Harmonization
This study is designed to confirm the efficacy of dasatinib 100mg once daily in producing a complete molecular response and to prove a possibility of "Operational Cure" in CMR patients.
- Trial name
- NCT02975115
- Testing
- RQ-PCR RNA Analysis
- Volunteers
- 102 people
- Sponsor
- Seoul St. Mary's Hospital
Thyroid Eye Disease
Evaluating the Efficacy and Safety of Teprotumumab N01 in Patients With Thyroid Eye Disease.
This is a prospective study designed to evaluate the efficacy and safety of Teprotumumab N01 in patients with Thyroid Eye Disease (TED).
- Trial name
- NCT07423013
- Testing
- [18F]AlF-NOTA-FAPI-04PET/CT, 5.0-T high-resolution MRI
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University Third Hospital
Stroke
Robotic Mirror Therapy System for Functional Recovery of Hemiplegic Arms
The investigators developed a real-time 2-axis mirror robot system as a simple add-on module for conventional mirror therapy using a closed feedback mechanism, which allows for real-time movement of the hemiplegic arm.
- Trial name
- NCT02878746
- Testing
- Robotic mirror therapy, Conventional mirror therapy
- Where
- South Korea
- Volunteers
- 2 people
- Sponsor
- Seoul National University Hospital
Arthropathy, Osteoarthritis
Antigravity Treadmill After Joint Arthroplasty
The study aims to evaluate the efficacy of antigravity treadmill training and body weight-supported treadmill training in the rehabilitation of elderly patients (60-75 years) following hip or knee arthroplasty.
- Trial name
- NCT07040878
- Testing
- Antigravity Treadmill Training, Body Weight-Supported Treadmill Training, Conventional rehabilitation
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Post-extubation Respiratory Failure
High-flow Conditioned Oxygen Therapy Versus Non-invasive Ventilation: Prevention of Post-extubation Failure
The main aim is to demonstrate whether the high flow conditioned oxygen therapy reduces the reintubation rate. Post-extubation respiratory failure risk will be stratified (as the randomization).
- Trial name
- NCT01191489
- Testing
- High Flow Conditioned Oxygen Therapy in High Risk Patients, Non-invasive mechanical ventilation, Conventional Oxygen Therapy
- Where
- 2 sites in Spain
- Volunteers
- 1,042 people
- Sponsor
- Hospital Infanta Sofia
Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
Increased Re-eradication Rate of Helicobacter Pylori by Adding N-acetylcystein or Metronidazole to the Triple Therapy
Compare efficacy and safety of 10-day triple therapy (rabeprazole, clarithromycin and amoxicillin) plus N-acetylcystein versus 10-day concomitant therapy (rabeprazole, clarithromycin, amoxicillin and metronidazole) for…
- Trial name
- NCT01572597
- Testing
- 10RAC+acetylcystein, 10RAC+metronidazole
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Symptomatic Irreversible Pulpitis (SIP), Dental Pain
Intraligamentary vs Inferior Alveolar Nerve Block for Pulpitis: A Randomized Clinical Trial
This multicenter randomized trial compares the clinical effectiveness of intraligamentary injection versus inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in mandibular molars.
- Conditions
- Symptomatic Irreversible Pulpitis (SIP), Dental Pain, Inferior Alveolar Nerve Block Failure, Local Anesthesia
- Trial name
- NCT07130760
- Testing
- Intraligamentary Injection, Inferior Alveolar Nerve Block
- Where
- 2 sites in Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aula Dental Avanzada
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.