Clinical trials: Dietary Intervention
Polycystic Ovary Syndrome
Lifestyle Intervention and Metformin for Women With Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine if the combination therapy of lifestyle intervention and use of Metformin together will improve ovulation induction and hyperandrogenemia in women with polycystic ovary syndrome, by…
- Trial name
- NCT00151411
- Testing
- Metformin, Lifestyle Intervention
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Inactivity
Project ALIVE (A Lifestyle Intervention Via Email)
The objective of this study is to test the effectiveness of an email-based diet and physical activity intervention on increasing physical activity and fruit and vegetable consumption and decreasing intake of saturated and trans…
- Trial name
- NCT00607009
- Testing
- ALIVE
- Volunteers
- 797 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Phlebitis, Thrombophlebitis
The Effectiveness of Topical Sesame Oil in Preventing Phlebitis at IV Cannula Sites in Adults
The goal of this randomised controlled trial is to determine the effectiveness of topical sesame oil in preventing phlebitis at peripheral intravenous (IV) cannula sites in adult patients within a cardiovascular and…
- Trial name
- NCT06216522
- Testing
- Topical Sesame Oil, Liquid paraffin oil
- Where
- Singapore
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Dietary Modification, Weight Loss
Feasibility of a Postpartum Lifestyle Intervention on the Cardiometabolic Risk Profile of GDM Women
The goal of the study is to investigate the effect of a lifestyle intervention program (adoption of exclusive breastfeeding, healthy diet and regular physical activity) on minimizing postpartum weight retention among women with…
- Conditions
- Dietary Modification, Weight Loss, Physical Activity, Breastfeeding
- Trial name
- DEPART (NCT02872402)
- Testing
- Lifestyle intervention, Active control lifestyle intervention
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laval University
HIV/AIDS
Changing Health Through Food Support (CHEFS) Program
UCSF and Project Open Hand (POH), a community based organization in San Francisco which provides meals and groceries to chronically ill clients in the Bay Area, have partnered to conduct an initial randomized controlled trial…
- Trial name
- CHEFS (NCT03191253)
- Testing
- Medically-appropriate meals and groceries
- Volunteers
- 191 people
- Sponsor
- University of California, San Francisco
Breast Cancer
Reducing Metabolic Syndrome Among Breast Cancer Survivors
Using a pilot 1-arm pre-post design, investigators will implement an intervention that is personalized, low burden (the majority of interactions are telephone coaching sessions), and delivered during the initial survivorship…
- Trial name
- NCT03719677
- Testing
- Habit development intervention
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Metabolic Syndrome, Obesity
Effects of Brisk Walking and Regular Intensity Exercise Interventions on Glycemic Control
Physical activity is shown to positively reduce the risk of developing both cardiovascular disease and type 2 diabetes. Current guidelines recommend 30-60 minutes of moderate intensity cardiorespiratory exercise five days per…
- Trial name
- NCT03227575
- Testing
- Exercise Intervention
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Plymouth State University
Food Preferences, Satiety and Food Intake
Sustainable and Inclusive Use of Alternative Proteins in Mediterranean Supply Chains (CIPROMED)
This study investigates the effects of foods enriched with alternative protein sources, including edible insects, microalgae, hemp, and legumes, on appetite regulation, satiety, food preferences, and metabolic health in healthy…
- Conditions
- Food Preferences, Satiety and Food Intake, Appetite Regulation, Overweight (BMI > 25)
- Trial name
- CIPROMED (NCT07553936)
- Testing
- Mediterranean Diet with Control Products (chronic phase), Mediterranean Diet with Insect Protein Bread (chronic phase), Mediterranean Diet with Seaweed-Based Burger (chronic phase)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), Liver Fibrosis
Isocaloric Navy-Bean Substitution in Adults With MASLD
This study is a 24-week randomized crossover feasibility trial evaluating an isocaloric navy-bean dietary substitution in 40 adults with metabolic dysfunction-associated steatotic liver disease (MASLD) and intermediate-stage…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), Liver Fibrosis, Metabolic Dysfunction-Associated Steatohepatitis (MASH)
- Trial name
- BEAN-MASLD (NCT07730853)
- Testing
- Dietary Supplement/Behavioral: Navy Bean-Rich Diet, Habitual Diet (Control)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
NAFLD, Diabetes Mellitus
Improving Detection and Evidence-based Care of NAFLD in Latinx and Black Patients With Type 2 Diabetes
The primary objective of this pilot study is to assess the feasibility and acceptability of an intervention for improved detection and evidence-based care of NAFLD in Latinx and Black patients with type 2 diabetes (T2D) in Duke…
- Trial name
- NAFLD-DM (NCT05844137)
- Testing
- NAFLD Education, diet/lifestyle support, T2D medication management
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Duke University
Gastrointestinal Cancer
EAT-ING: Enhancing Anticancer Treatment Safety Via Immunomodulatory Nutritional Support in Advanced Gastrointestinal Cancers
The use of immunomodulants in patients with GI cancer has been progressively gaining attention in the last years, as a high-calorie-high-protein nutritional blend enriched in immunonutrients has shown efficacy in several studies…
- Trial name
- EAT-ING (NCT07590622)
- Testing
- LH BLU, ONS
- Volunteers
- 88 people
- Sponsor
- IRCCS San Raffaele
Gallbladder; Functional Disturbance
The Optimal Measurement Time for the New Gallbladder Function Assessment Method
This is a multicenter, prospective, randomized, double-blind, crossover study involving healthy individuals, aiming to evaluate the stability of oral protein bars + olive oil as a new method for determining gallbladder…
- Trial name
- NCT07321431
- Testing
- oral administration of 2 fried eggs, oral protein bars + 50ml olive oil
- Where
- 5 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Type 2 Diabetes
Prevention of Type 2 Diabetes Amongst South Asians With Central Obesity and Prediabetes
The investigators' general goal is to identify approaches to risk stratification and health promotion through lifestyle modification that are acceptable, effective and efficient for prevention of T2D in South Asian communities…
- Trial name
- iHealth-T2D (NCT02949739)
- Testing
- Intensive lifestyle modification
- Where
- United Kingdom
- Volunteers
- 5,244 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Acne Vulgaris
Effect of a Low-glycemic-load and Milk-free Diet on Acne Severity
The objective of this study is to assess the effect of a low-glycemic-load and milk-free diet on acne severity. IGF-1 and a phosphorylated product of the mTORC pathway (p70S6K) will be assessed in both groups to explore the mTORC…
- Trial name
- NCT01969175
- Testing
- Low-glycemic-load and milk-free diet
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Parc Taulí Hospital Universitari
Metabolic Syndrome
Canola Oil Multicentre Intervention Trial
The purpose of the study is to examine how the consumption of different dietary oil varieties affects a broad range of metabolic responses that are important in the development of cardiovascular diseases.
- Trial name
- COMIT (NCT01351012)
- Testing
- Corn and safflower oil, Canola oil, High oleic acid canola oil
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- University of Manitoba
Healthy
Impact of Protein Content of Ultraprocessed Foods on the Regulation of Energy Balance
Aim of the study is to investigate the effects of high-protein, ultraprocessed foods on the regulation of energy balance in a metabolic chamber.
- Trial name
- NCT05337007
- Testing
- high protein diet, moderate protein diet
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Kiel
Autism Spectrum Disorder
An Integrated Nutrition Intervention to Promote Healthy Eating Habits for Children With ASD
There is an unmet need for nutrition interventions that address both autism spectrum disorder (ASD) specific feeding challenges and unbalanced eating habits among children with ASD to prevent future chronic health conditions.
- Trial name
- NCT05194345
- Testing
- Autism Eats nutrition intervention, We Can! enhanced usual care
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of South Florida
Healthy, Overweight
Study to Evaluate the Effect of Gum Acacia (FibregumTM) on Post-prandial Glucose, Insulin Levels and Food Intake
Study to evaluate the effect of gum acacia (FibregumTM) on post-prandial glucose and insulin levels and food intake in normal-weight and overweight subjects during a 2-7 weeks intervention period.
- Trial name
- NCT04515277
- Testing
- 40 g Gum acacia (FibregumTM), 20 g Gum acacia (FibregumTM), 0 g Gum acacia (FibregumTM)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Nexira
Muscle Mass and Strength
Effects of Resistance Exercise Among TGD Individuals Initiating Estrogen-Based Gender-Affirming Hormone Therapy
Estrogen-dominant gender-affirming hormone therapy (GAHT) is standard of care for transgender women and gender-diverse individuals and typically consists of estrogen together with anti-androgen/ testosterone therapy.
- Trial name
- STRENGTH (NCT07400419)
- Testing
- Resistance Exercise Program, Nutrition and Exercise Counseling
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
High Blood Pressure
Immediate Pressor Response to Oral Salt
The goal of this study is to establish a diagnostic accuracy of an immediate pressor response to oral salt (IPROS) to identify salt sensitivity of blood pressure (SSBP)
- Trial name
- IPROS (NCT06226636)
- Testing
- salt
- Where
- 2 sites in Zambia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mulungushi University
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