Clinical trials: Dietary Intervention
Obesity, Menopause
Aging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal Women
In postmenopausal women, obesity increases the risk of physical function decline, premature aging, and vascular dysfunction. Semaglutide and tirzepatide are potent obesity medications.
- Trial name
- NCT07057310
- Testing
- semaglutide or tirzepatide, Lifestyle modification intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Cardiovascular Diseases, Coronary Artery Disease
ISCHEMIA-Chronic Kidney Disease Trial
The purpose of the ISCHEMIA-CKD trial is to determine the best management strategy for patients with stable ischemic heart disease (SIHD), at least moderate inducible ischemia and advanced chronic kidney disease (CKD; estimated…
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- ISCHEMIA-CKD (NCT01985360)
- Testing
- Cardiac Catheterization, Coronary Artery Bypass Graft Surgery, Percutaneous Coronary Intervention
- Where
- United States
- Volunteers
- 777 people
- Sponsor
- NYU Langone Health
Nutritional Requirements
Displacement of Iodine Balance Value During Pregnancy and the Mechanism of Breast Iodine Homeostasis During Lactation
In order to solve the bottleneck problems of"zero balance displacement"and"large variation of breastmilk"in the study of iodine EAR of pregnant women, lactating women and infants, firstly, this study intends to clarify the rate…
- Trial name
- NCT05730803
- Testing
- dietary intervention
- Where
- 2 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Inflammatory Bowel Disease
Research on the Use of Probiotics in the Prevention and Treatment of Inflammatory Bowel Disease
This study evaluates oral Lactobacillus reuteri as an adjunct therapy for 2 months. Endoscopic assessments will be performed at baseline and after 2 months of intervention to evaluate intestinal inflammation.
- Trial name
- NCT06781827
- Testing
- Probiotic
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Wecare Probiotics Co., Ltd.
Obesity
A web-and Mobile Phone-based Intervention in 4-year-olds: a Population-based Randomized Controlled Trial
This study aims to evaluate the effects of a mobile phone-based dietary and physical activity intervention on body fatness, dietary intake and physical activity of preschoolers
- Trial name
- NCT02021786
- Testing
- Mobile phone based intervention
- Where
- Sweden
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Acute Lymphoblastic Leukemia
Effect of Omega-3 Fatty Acids on Methotrexate Induced Hepatotoxicity in Children With Acute Lymphoblastic Leukemia
Study the role of oxidative stress in methotrexate induced hepatic damage, and the possible protective effect of OMEGA-3 fatty acids against methotrexate hepatotoxicity using clinical and biochemical parameters.
- Trial name
- NCT02373579
- Testing
- Omega-3 Fatty Acids, Methotrexate
- Volunteers
- 70 people
- Sponsor
- Nancy Samir Elbarbary
Chronic Stroke
Protein Supplementation for Chronic Stroke Treatment
Stroke patients usually have difficulties with moving and are venerable to secondary problems such as sarcopenia and strength loss. These problems may accelerate the disability process during aging.
- Trial name
- NCT03637270
- Testing
- Dietary supplementation, Exercise training
- Where
- 4 sites in Taiwan
- Volunteers
- 114 people
- Sponsor
- Taipei Medical University WanFang Hospital
Partial-thickness Burn
Effect of Enteral Albumin on Healing of Superficial Partial Thickness Fresh Flame Burns of Adults
Patients with 10 to 20% Superficial partial thickness fresh flame burn will be recruited. Burn thickness will be confirmed by using Laser Doppler.
- Trial name
- NCT03709069
- Testing
- Albumin supplementation
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- King Edward Medical University
Metabolism and Nutrition Disorders
The CoCoS Interventional Trial: Caloric Control in Cardiac Surgery Patients
Background: Malnutrition is widespread among cardiac surgery patients and is independently related to an adverse postoperative evolution or outcome.
- Trial name
- NCT02902341
- Testing
- Nutrition Therapy, Control
- Volunteers
- 351 people
- Sponsor
- Universitair Ziekenhuis Brussel
Diabetes Mellitus Type 2, Dyslipidemia
Low Calorie Diet and Diabetes
The primary hypothesis is to investigate whether a low calorie diet for 7 weeks followed by continuous lifestyle advice is an effective option to achieve an improvement in glucose control as measured by HbA1c after 52 and 104…
- Conditions
- Diabetes Mellitus Type 2, Dyslipidemia, Non-alcoholic Fatty Liver Disease, Obesity
- Trial name
- LCD (NCT02498990)
- Testing
- Low calorie diet followed by life style intervention
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska University Hospital
Hypertension
Dietary Counseling to Reduce Salt Intake in Patients With High Blood Pressure
High salt diet increases risk of development of hypertension. In hypertensive patients, low salt diet decreases blood pressure. Not surprisingly public health authorities endorse low salt diet in hypertensive patients.
- Trial name
- NCT02283697
- Testing
- Dietary Counseling, Control: Standard Care
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Ottawa Hospital Research Institute
Cardiovascular Health
Impact of a Pedagogical Intervention on Children Cardiovascular Risk Factors
In Bogotá, Colombia, the Fundación Cadioinfantil performed a randomized and controlled community trial, to evaluate the impact of a pedagogical intervention (PI) on cardiovascular health towards an active lifestyle and healthy…
- Trial name
- NCT03579810
- Testing
- Investigational, Control
- Where
- Colombia
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- Fundación Cardioinfantil Instituto de Cardiología
Obesity, Diabetes
Randomized Clinical Trial; Medical vs Bariatric Surgery for Adolescents (13-16 y) With Severe Obesity
Severe childhood obesity is associated with both immediate and chronic health problems and a severe impact on psychosocial development.
- Conditions
- Obesity, Diabetes, Hypertension, Steatohepatitis
- Trial name
- AMOS2 (NCT02378259)
- Testing
- Laparoscopic Roux-en-Y gastric bypass, Intense conservative treatment
- Where
- 3 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Göteborg University
Obesity, Overweight
Smart Technology for Weight Loss and Metabolic Health
The study will evaluate whether a technology-based lifestyle intervention program using primarily a smartphone platform is an acceptable and effective way for treating obesity.
- Conditions
- Obesity, Overweight, Prediabetes, Weight Loss
- Trial name
- NCT02742662
- Testing
- Wearable technology, smartscale, Smartphone applications, Standard Weight Management Visits
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Temple University
Nutrition Habits, Biomarkers / Hair
Epigenetic Optimization Through Biofrequency Nutrition
Biomarker-based nutrition has demonstrated superior efficacy compared to population-level approaches in improving health outcomes.
- Conditions
- Nutrition Habits, Biomarkers / Hair, Epigenetic
- Trial name
- NCT07093242
- Testing
- Personalized Nutritional Follow-Up
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Mild Cognitive Impairment, Mild Dementia
Shanghai Non-pharmacological Intervention for Mild Cognitive Impairment and Mild Alzheimer's Disease
This study is a multicentre, randomized, double-blind, controlled trial that aims to investigate the efficacy of multi-domain life-style intervention including low inflammatory-index diet, exercise, and cognitive training in…
- Trial name
- SIM-2 (NCT05887674)
- Testing
- Diet intervention, Exercise, Cognitive training
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Ruijin Hospital
Fructose Metabolism Disorder
Low Fructose Diet in Diabetes Type 2
Diabetes is one of the most common and chronic diseases in the world, with the prevalence and incidence of this disease rising in most societies, especially in Iran.
- Trial name
- NCT03352596
- Testing
- low frutose diet
- Volunteers
- 48 people
- Sponsor
- National Nutrition and Food Technology Institute
Vascular; Change, Dietary Modification
On-Line Intervention to Lower Cardiovascular Risk in Pediatric Heart Transplant Patients
Pediatric heart transplant patients have a high-risk cardiovascular profile affecting their long-term outcomes and survival. Currently, no effective cardiovascular preventative care is provided for this pediatric population, in…
- Conditions
- Vascular; Change, Dietary Modification, Physical Activity, Health Behavior
- Trial name
- NCT02519946
- Testing
- On-Line Diet and Exercise Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Stanford University
Nutrition Knowledge, Dietary Diversity
Dialogic Reading-Based Nutrition Education on Preschool Children
This study aims to evaluate the effectiveness of a dialogic reading-based nutrition education program in improving nutrition knowledge and dietary diversity among preschool children.
- Trial name
- NCT07170696
- Testing
- nutrition education
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Type 2 Diabetes Mellitus (T2DM), Obesity (Disorder)
Digital Dietary Intervention for Patients Receiving GLP-1 Receptor Agonist Therapy
The goal of this clinical trial is to learn whether adding the NutriSteppe digital dietary intervention to routine medical care improves metabolic health in adults aged 21 to 65 years with type 2 diabetes mellitus, obesity, or…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Obesity (Disorder), Overweight, Metabolic Syndrome
- Trial name
- NutriSteppe (NCT07728669)
- Testing
- NutriSteppe Digital Dietary Intervention
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- Kazakh Academy of Nutrition
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