Clinical trials: Dietary Intervention
Breast Cancer
FMD and Neoadjuvant Chemo-immunotherapy in TNBC
The primary objective of this study is to investigate the efficacy and safety of a fasting-mimicking diet (FMD) intervention combined with standard neoadjuvant chemoimmunotherapy in early-stage or locally advanced triple-negative…
- Trial name
- FACT-TN (NCT07378306)
- Testing
- Fasting-mimicking diet, Chemotherapy, Toripalimab
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-sen University
Cognitive Function, Dementia
MIND Diet and Cognitive Function in Middle-aged and Older Adults
A 12-month cluster-randomized controlled trial designed to test the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet education on the rate of cognitive change and several other secondary…
- Trial name
- NCT06417749
- Testing
- Control arm, Intervention arm
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Cognitive Decline, Dementia, Vascular
Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients
To test the effects of a 2- to 3-year intervention of the MIND diet versus usual post-stroke care on cognitive decline, the characteristic feature of dementia, and on brain biomarkers of Alzheimer's Disease (AD) and vascular…
- Conditions
- Cognitive Decline, Dementia, Vascular, Alzheimer Disease, Dementia
- Trial name
- NCT04337255
- Testing
- Behavioral Dietary intervention ( MIND Diet), Behavioral Usual Care Diet Intervention
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- Rush University Medical Center
Healthy
Endogenous vs. Exogenous Ketone Bodies
Aim of the study is to compare the origin of ketone bodies: endogenous ketone bodies due to 36 hours fasting or 24 hours of ketogenic diet vs. exogenous ketone bodies as supplements additional to normal diet.
- Trial name
- NCT04490226
- Testing
- Beta-Hydroxybutyrate as Ca-Mg-salt, active, ketogenic diet (KetoCal® 4:1 Neutral, Nutricia GmbH, Erlangen, Germany), active, fasting, active
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Kiel
Overweight, Obesity
Effect of the Prescription of 10,000 Steps Per Day Using a Pedometer APP in the Body Composition of Overweight Adults
This study aimed the effect of the Accupedo pedometer smartphone app intervention, with goal setting of walking prescription of 10,000 steps per day, in overweight adults.
- Trial name
- NCT03845478
- Testing
- Control Group (CG), Intervention Group (IG)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad de Córdoba
Overweight and Obesity, Healthy Diet
Acute Intervention to Assess the Impact of Practical Strategies for Healthy Eating
Obesity has reached epidemic proportions globally, alongside its associated comorbidities including cardiovascular diseases, diabetes and cancer.
- Trial name
- PORTIONS-3 (NCT05619276)
- Testing
- Standard serving utensil toolkit, Optimsed portion-control toolkit
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Polycystic Ovary Syndrome, Oligomenorrhea
Acupuncture for Oligomenorrhea Due to Polycystic Ovary Syndrome
This study is an international multicenter, pilot randomized, assessor-blind, controlled trial, which is aimed to preliminarily investigate the efficacy and safety of acupuncture on oligomenorrhea due to polycystic ovary syndrome…
- Trial name
- NCT04509817
- Testing
- Acupuncture+Usual care, Usual care
- Where
- 3 sites in China, South Korea
- Volunteers
- 60 people
- Sponsor
- China Academy of Chinese Medical Sciences
Obesity
The Impact of a Pre-Operative Exercise Program on Fitness Outcomes Following Bariatric Surgery
BACKGROUND: Obesity is a global epidemic and Canada has one of the highest obesity rates in westernized countries. Obesity has many health related complications, including high blood pressure, high cholesterol, diabetes, sleep…
- Trial name
- NCT02010489
- Testing
- 12 week Exercise Program
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Breast Cancer, Weight Loss
Lifestyle, Exercise and Nutrition Study 1
The specific aims of this study are to determine the efficacy and cost-effectiveness of a weight loss program compared with usual care (control) treatment on 6-month changes in body weight, body fat, and serum hormones in breast…
- Trial name
- LEAN (NCT02109068)
- Testing
- Weight Loss Counseling- Phone, Weight Loss Counseling- In-Person
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
HIV, Cardiovascular Disease
Men Together Making a Difference: Health Promotion for Black Men
African American men infected with HIV are living longer and are acquiring the same chronic non-communicable diseases affecting the general population of African American men age 40 years and older.
- Conditions
- HIV, Cardiovascular Disease, Diabetes, Hypertension
- Trial name
- NCT02572414
- Testing
- Health Promotion Intervention, Health Awareness Control Intervention
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- University of Pennsylvania
Type 2 Diabetes Mellitus
Preventive Effectiveness of Primary Care Physician-led CGM-supported Comprehensive Intervention on Cardio-metabolic-immune Diseases in Community Patients With Type 2 Diabetes (Community Diabetes Control Project)
This community-based trial evaluates whether primary care physicians, equipped with continuous glucose monitoring (CGM) and trained under a standardized protocol with specialist backup, can improve diabetes outcomes through…
- Trial name
- CDCP (NCT07885904)
- Testing
- comprehensive intervention
- Where
- China
- Volunteers
- 15,400 people
- Sponsor
- Xiangya Hospital of Central South University
Colorectal Cancer, Obesity
Energy Balance Interventions for Colorectal Cancer Prevention
RATIONALE: Calories and physical exercise may affect the risk of developing cancer. It is not yet known whether a low-calorie diet and/or physical activity program is effective in preventing cancer in participants at increased…
- Trial name
- NCT00653484
- Testing
- Physical Activity, Energy Restriction, Physical Activity and Energy Restriction
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University
Healthy Aging
Vestibular Stimulation, Exercise and Light Optimization for Circadian Clock Enhancement (Velocce)
This study investigates the effects of remote interventions based on the exposure to one or more zeitgebers (i.e. adapted physical activity alone or combined with bright light exposure, or galvanic vestibular stimulation)…
- Trial name
- velocce (NCT05030389)
- Testing
- Adapted Physical Activity (APA), Bright Light Exposure (BLE), Galvanic Vestibular Stimulation (GVS)
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Université de Caen Normandie
Type 2 Diabetes
Development of Self-Regulation in Individuals With Type 2 Diabetes
The purpose of this investigation is to conduct a 12-week study to compare the effects of a self-regulation intervention (SR), in which participants will self-monitor their blood glucose (BG) and adjust dietary intake and…
- Trial name
- NCT00941447
- Testing
- Dietary, Physical Activity, Self-Regulatory Approaches
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Tennessee, Knoxville
Nocturnal Enuresis in Children, Primary Nocturnal Enuresis
Potential Adjuvant Therapies for Children With Primary Nocturnal Enuresis
To examine the possible reduction in dietary salt intake on the outcomes of nocturnal enuresis
- Trial name
- NCT07876947
- Testing
- Dietary Salt Restriction, Omega Supplementation
- Volunteers
- 100 people
- Sponsor
- Cairo University
Mild Cognitive Impairment (MCI)
Effects of Hydroxytyrosol-Rich Olive Polyphenol Dietary Supplement Combined With Mediterranean Diet Adherence on the Cognitive Health of Patients With Mild Cognitive Impairment
Nutrition is an important modifiable risk factor of human cognitive health. Increasing data suggests that certain nutrients or food ingredients, such as plant polyphenols, have the potential to benefit cognitive abilities even in…
- Trial name
- MEDIPHENO-HT (NCT07672938)
- Testing
- Low-Dose Hydroxytyrosol-Rich Olive Juice Polyphenol Supplement, High-Dose Hydroxytyrosol-Rich Olive Juice Polyphenol Supplement
- Where
- Greece
- Volunteers
- 141 people
- Sponsor
- Panhellenic Federation of Alzheimer's Disease and Related Disorders
Weight Loss, Pelvic Floor Disorders
Medical Weight Loss on Pelvic Floor Dysfunction
The goal of this observational study is to learn about the effect of medical weight loss on the symptom of pelvic floor dysfunction in obese and overweight women.
- Trial name
- WLPFD (NCT05987085)
- Testing
- Diet and exercise
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Cardiovascular Disease (CKD), Hyperphosphatemia
Behavioral Management of Phosphorus in Hemodialysis Patients
The purpose of this randomized clinical trial is to evaluate alternative technology-supported behavioral approaches to engaging 42 maintenance hemodialysis (HD) patients with persistent hyperphosphatemia in phosphorus binder…
- Trial name
- NCT02940743
- Testing
- Education (Edu), SM intervention, Social Cognitive Therapy (SCT)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- NYU Langone Health
Overfed, Obesity
Experimental Overfeeding in Humans
The objective of this study is to determine the homeostatic mechanisms that counteract weight gain in response to experimental overfeeding.
- Trial name
- ExpO (NCT04065243)
- Testing
- Overfeeding diet, Isocaloric diet
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Diabetes, Diabetes Mellitus
Validation of an App in the Elderly Population With Diabetes Mellitus.
A randomized clinical trial comparing the intervention group, which will use a mobile app, with the control group (without a mobile app).
- Conditions
- Diabetes, Diabetes Mellitus, Elderly, ELDERLY PEOPLE
- Trial name
- SMARTDIABETES (NCT07591415)
- Testing
- Smartdiabetes
- Where
- 3 sites in Spain, Sweden
- Volunteers
- 60 people
- Sponsor
- Leocadio Rodriguez Mañas
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