Clinical trials: Doxycycline, completed
Healthy Volunteers, Fungal Infections
A Pilot of Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity
This study will examine the phototoxicity, a reaction to light that is like exaggerated sunburn, which occurs in people who take medications such as voriconazole, a medication used to fight fungus.
- Conditions
- Healthy Volunteers, Fungal Infections, Bacterial Infections
- Trial name
- NCT00353158
- Testing
- Doxycycline, Voriconazole
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Advanced Malignant Neoplasm, Dermatologic Complication
Spironolactone in Preventing Rash in Patients With Advanced Cancer Receiving Panitumumab and Cetuximab
This randomized phase II trial studies how well giving spironolactone works in preventing rash in patients with cancer that has spread to other places in the body and are receiving panitumumab and cetuximab.
- Trial name
- NCT01867294
- Testing
- Doxycycline, Management of Therapy Complications, Questionnaire Administration
- Where
- 5 sites in United States
- Volunteers
- 19 people
- Sponsor
- Academic and Community Cancer Research United
Drug-induced Nausea and Vomiting
Scheduled Prophylactic Antiemetics for Reduction of Emesis With Doxycycline (SPARED) Trial
Background/Purpose of the Study Doxycycline is an antibiotic used for infection prevention before surgical pregnancy termination, and a side effect of it is nausea/vomiting.
- Trial name
- SPARED (NCT02456662)
- Testing
- Ondansetron
- Where
- United States
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- University of Rochester
First Trimester Abortion
A Randomized Controlled Trial of Three Antibiotic Regimens for First Trimester Abortions
This study, a double blinded randomized controlled trial, is being done to compare side effects of commonly used antibiotic regimens prior to same day abortion procedures.
- Trial name
- NCT02756403
- Testing
- Azithromycin, Doxycycline, Metronidazole
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Amyloidosis; Systemic
BCD With or Without Doxycycline in Mayo Stage II-III Light Chain Amyloidosis Patients
Survival of intermediate and high-risk primary light chain amyloidosis (pAL) remains poor due to high mortality within 3-6 months of diagnosis.
- Trial name
- NCT03401372
- Testing
- Doxycycline, Bortezomib, Cyclophosphamide
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Jian Li
Posterior Blepharitis
Oral Azithromycin Versus Doxycycline in Posterior Blepharitis
One hundred patients with the diagnosis of posterior blepharitis based on history taking and proper physical examinations by two experienced ophthalmologists will include in the study.
- Trial name
- NCT01783860
- Testing
- Azithromycin, Doxycycline
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Tehran University of Medical Sciences
Malaria
Artemisinin Resistance in Bangladesh
A randomized, controlled clinical trial conducted in Southeastern Bangladesh using artesunate monotherapy to determine the baseline sensitivity of P. falciparum to artemisinins.
- Trial name
- NCT00639873
- Testing
- Artesunate, quinine-doxycycline
- Where
- Bangladesh
- Volunteers
- 126 people
- Sponsor
- Medical University of Vienna
Dermatitis, Atopic
Topical NanoDox® for Atopic Dermatitis
This study will investigate the safety and clinical efficacy of a novel doxycycline topical formulation in subjects with Atopic Dermatitis (AD).
- Trial name
- NCT02910011
- Testing
- Nanodox 1% (doxycycline monohydrate hydrogel)
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- University of Florida
Helicobacter Pylori Infection
Saccharomyces Boulardii as Pretreatment Before Rescue Therapy of Helicobacter Pylori
The increasing rate of drug resistance in often leads to eradication failure and the need for rescue therapy, and it is of great significance to explore new rescue therapeutic regimens.
- Trial name
- NCT05191875
- Testing
- Saccharomyces Boulardii 250 MG, Ilaprazole.Doxycycline. Furazolidone. Colloidal Bismuth Tartrate
- Where
- China
- Volunteers
- 106 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Chronic Rhinosinusitis, Nasal Polyps
Influence of Oral Doxycycline on Wound Healing After Endonasal Endoscopic Sinus Surgery for Chronic Rhinosinusitis With and Without Nasal Polyposis: a Double-blind Randomized Placebo-controlled Trial
This is a randomized, double blind, placebo controlled, parallel group, study in patients with chronic rhinosinusitis with or without nasal polyps.
- Trial name
- DOXYPOSTOP (NCT01198912)
- Testing
- doxycycline 100 mg
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 33 people
- Sponsor
- University Hospital, Ghent
Periodontitis
Effects of Low-Dose Doxycycline on Oral Bone Loss
The primary purpose of this clinical trial is to determine whether low-dose doxycycline can reduce alveolar bone density loss in postmenopausal osteopenic women with periodontitis and not on hormone replacement therapy (i.e.…
- Trial name
- NCT00066027
- Testing
- 20 mg doxycycline hyclate
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- University of Nebraska
Acne Vulgaris
Aczone 5% Gel as Maintenance Treatment of Acne Vulgaris Following Completion of Oral Doxycycline and Aczone 5% Gel
This pilot study will explore if continuation of treatment of treatment with Aczone 5% gel following combination treatment with with doxycycline and Aczone 5% gel can maintain therapeutic response.
- Trial name
- NCT01885910
- Testing
- Doxycycline 100mg, Aczone 5% gel
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Derm Research, PLLC
Coronary Artery Bypass Grafting, Cardiopulmonary Bypass
Protection of the Heart With Doxycycline During Coronary Artery Bypass Grafting
The purpose of this study is to determine whether doxycycline (Periostat) at a sub-antimicrobial dose will decrease reperfusion injury after coronary artery bypass grafting (CABG) surgery with cardiopulmonary bypass (CPB).
- Conditions
- Coronary Artery Bypass Grafting, Cardiopulmonary Bypass, Reperfusion Injury
- Trial name
- NCT00246740
- Testing
- Periostat
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Alberta
Persian Gulf Syndrome, Mycoplasma Infections
Antibiotic Treatment of Gulf War Veterans' Illnesses
In 1990 and 1991, the U.S. deployed approximately 700,000 troops to the Persian Gulf to liberate Kuwait from Iraqi occupation. While there were few casualties associated with the Gulf War, many individuals returned from this…
- Trial name
- NCT00007735
- Where
- 27 sites in United States, Puerto Rico
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Acne Vulgaris
Placebo Controlled Efficacy and Safety Study of CD2475/101 40 mg Tablets vs. Placebo and Doxycycline 100 mg Capsules Once Daily in the Treatment of Inflammatory Lesions of Acne Vulgaris
The primary objectives of the study is to show CD2475/101 40mg tablets taken once a day for 16 weeks is superior to the placebo in Change from baseline to Week 16(Last Observation Carry Forward, Intent To Treat) in inflammatory…
- Trial name
- NCT01320033
- Testing
- CD2475/101 40 mg, Doxycycline 100 mg
- Where
- 31 sites in United States
- Volunteers
- 662 people
- Sponsor
- Galderma R&D
Periodontal Disease, Type 2 Diabetes
Comparison Between aPDT and Systemic Doxycycline on Non-surgical Periodontal Therapy in Type 2 Diabetics
The objective of this study is to evaluate Photodynamic Therapy (PDT) as adjunct on non surgical periodontal therapy in patients with type 2 diabetes. A total of 40 individuals will be selected and divided in two groups.
- Trial name
- NCT01595594
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Periodontitis, Periodontal Diseases
Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers
The purpose of this study is to determine in current and non-smokers the clinical and microbiological effects of 3 therapies: scaling and root planing (SRP) alone; SRP in combination with the orally administered antibiotic…
- Trial name
- NCT00066066
- Testing
- Scaling and root planing, Metronidazole, Amoxicillin
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- The Forsyth Institute
Neuroborreliosis, Borrelia Burgdorferi
Six Versus Two Weeks Treatment With Doxycycline in Lyme Neuroborreliosis
Comparison of Doxycycline 200 mg once daily for six weeks versus Doxycycline 200 mg once daily for two weeks + placebo for four weeks.
- Trial name
- NCT02553473
- Testing
- Doxycycline
- Volunteers
- 121 people
- Sponsor
- Sorlandet Hospital HF
Covid19
Effectiveness of Ivermectin and Doxycycline on COVID-19 Patients
A randomized controlled trial on using Ivermectin and doxycycline to treat mild-moderate outpatients, severe, and critical inpatients of Coronavirus disease 19 (COVID-19) along with standard of care.
- Trial name
- NCT04591600
- Testing
- Ivermectin and Doxycyline, Standard of care
- Where
- Iraq
- Volunteers
- 140 people
- Sponsor
- Alkarkh Health Directorate-Baghdad
Syphilis
Clinical Trial of Doxycycline VS BPG for Early Syphilis (SY-DOXY)
According to European and US Centers for Disease Control and Prevention (CDC) guidelines, the recommended treatment for uncomplicated early syphilis in adults (i.e.
- Trial name
- SY-DOXY (NCT04838717)
- Testing
- BPG, Doxycycline
- Where
- 7 sites in France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris