Clinical trials: Duloxetine
Major Depressive Disorder (MDD)
Study of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With Depression
The purpose of this study is to evaluate the efficacy and safety of Ammoxetine hydrochloride enteric-coated tablets in subjects with depression.
- Trial name
- NCT05018013
- Testing
- Ammoxetine hydrochloride enteric-coated tablets, Duloxetine hydrochloride enteric-coated capsules
- Where
- China
- Volunteers
- 240 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Cardiovascular Diseases (CVD), Depression Anxiety Disorder
Effect of Exercise on Tapering Antipsychotics in Patients With Psycho-cardiological Disease(EXTRA-study)
Psycho-Cardiological Disease studies the complex links between the cardiovascular system and emotions. The two diseases are now the focus of public health organizations, forming a vicious circle of mutual influence.
- Trial name
- NCT07025590
- Testing
- Moderate-intensity continuous movement and Antipsychotics intervention, Antipsychotics intervention(sertraline, escitalopram, fluoxetine, duloxetine, paroxetine, venlafaxine, and fluvoxamine)
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Guangdong Provincial People's Hospital
Attention Deficit Disorder With Hyperactivity
Pilot Study of Duloxetine in Adult Attention Deficit Hyperactivity Disorder(ADHD)
The purpose of this study is to determine whether duloxetine is an effective treatment of attention deficit disorder in adults.
- Trial name
- NCT00940693
- Testing
- duloxetine
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Université de Montréal
Anxious Depression, Depression
Determining Optimal Treatment Sequences in Anxious Depression (DOTS-AD)
Acute, double-blind, adaptively randomized treatment with duloxetine or escitalopram, followed by double-blind, randomized adjunctive treatment with clonazepam or pregabalin for persistent symptoms.
- Trial name
- DOTS-AD (NCT04245748)
- Testing
- Escitalopram, Duloxetine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Cincinnati
Posttraumatic Stress Disorder
Effects of Duloxetine on Fear Conditioning in Posttraumatic Stress Disorder (PTSD)
Chronic posttraumatic stress disorder (PTSD) is a debilitating disorder and treatment response to pharmacological interventions has been modest for these patients.
- Trial name
- NCT00763178
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Yale University
Diabetic Peripheral Neuropathic Pain
A Study of Duloxetine (LY248686) in Participants With Diabetic Peripheral Neuropathic Pain (DPNP)
The main purpose of this study is to evaluate the effectiveness and safety of the study drug known as duloxetine in participants with diabetic peripheral neuropathic pain.
- Trial name
- NCT02417935
- Testing
- Duloxetine, Pregabalin
- Volunteers
- 304 people
- Sponsor
- Eli Lilly and Company
Total Knee Arthroplasty, Osteoarthritis, Knee
Comparison of Opioid and Duloxetine for Postoperative Pain Control After Total Knee Arthroplasty: RCT
Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) has recently been reported to be effective in controlling pain in persistent chronic pain caused by joint surgery and arthritis.
- Trial name
- NCT04719585
- Testing
- Duloxetine vs. Opioid
- Volunteers
- 160 people
- Sponsor
- The Catholic University of Korea
Pain, Postoperative
Duloxetine for Postoperative Pain of Laparoscopic Cholecystectomy
Recent studies on the impact of perioperative duloxetine for treatment of acute postoperative pain have yielded positive outcomes with respect to reduction opioid consumption.
- Trial name
- NCT05115123
- Testing
- Duloxetine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Functional Disorder
Patient Education and Duloxetine, Alone and in Combination, for Patients With Multisystem Functional Somatic Disorder
The goal of this clinical trial is to test if patient education or duloxetine can be used to treat multisystem functional somatic disorder (FSD).
- Trial name
- EDULOX (NCT06232473)
- Testing
- Patient Education, Duloxetine, Enhanced usual care
- Where
- Denmark
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Depressive Disorder, Major
Combining Data Sources to Identify Effect Moderation for Personalized Mental Health
This work will extend and apply methods for modeling heterogeneous treatment effects when multiple studies are available, with a particular focus on the complexities in mental health research.
- Trial name
- NCT05267873
- Testing
- Duloxetine, Vortioxetine
- Where
- United States
- Volunteers
- 9,586 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Psychotic Disorders
Treatment of MDEs During the Course of Psychotic Disorders With Duloxetine
We evaluate the efficacy and tolerability of duloxetine in the treatment of major depressive episodes during the course of psychotic disorders
- Trial name
- NCT00224302
- Testing
- Duloxetine
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Neuropathy in Cacer Patien
Comparison of the Efficacy and Safety of Duloxetine Augmented With Gabapentin and Duloxetine Augmented With Amitriptyline vs Duloxetine Alone in Chemotherapy -Induced Neuropathy
This study aimed to elucidate the relationship between the Efficacy and Safety of Comparison of the Efficacy and Safety Duloxetine augmented with gabapentin and amitriptyline augmented with Duloxetine vs duloxetine alone in…
- Trial name
- NCT06091553
- Testing
- Duloxetine alone, Duloxetine augmented with gabapentin, Duloxetine augmented with amitriptyline (as combined therapy)
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Beni-Suef University
Depression
Duloxetine vs. Active Comparator in the Treatment of Patients With Depression
How duloxetine compares to a medication currently available for the treatment of patients diagnosed with depression
- Trial name
- NCT00071695
- Testing
- Duloxetine Hydrochloride, Venlafaxine Extended Release
- Where
- France
- Volunteers
- 320 people
- Sponsor
- Eli Lilly and Company
Low Back Pain
Imaging Study of Chronic Low Back Pain in Patients Taking Pain Medication
Duloxetine has recently been shown to be effective in reducing the pain in chronic pain patients. Duloxetine is known to exert a central mechanism, however the precise human brain structures responsible for mediating its…
- Trial name
- NCT00388414
- Testing
- duloxetine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Stanford University
Major Depressive Disorder, Magnetic Resonance Imaging
Multimodal Magnetic Resonance Imaging-based Study of Electroconvulsive Efficacy Prediction in Adolescents With Depression: a Multicenter Prospective Cohort Study
The aim of this project is to investigate the multimodal magnetic resonance brain imaging changes in adolescents with major depressive disorder (MDD) before and after electroconvulsive therapy.
- Conditions
- Major Depressive Disorder, Magnetic Resonance Imaging, Electroconvulsive Therapy
- Trial name
- NCT05889234
- Testing
- Modified Electroconvulsive Therapy, Conventional pharmacotherapy
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Major Depressive Disorder
SPD489 Adult Major Depressive Disorder (MDD) Open-label Safety and Tolerability Rollover Extension Study
This study is an optional continuation of previous short-term adult major depressive disorder (MDD) augmentation studies. Patients may only take part in this long-term, open-label research study if they completed a previous…
- Trial name
- NCT01436175
- Testing
- SPD489 (Lisdexamfetamine dimesylate) + Antidepressant
- Where
- 212 sites in United States, Canada and 12 more
- Volunteers
- 1,570 people
- Sponsor
- Shire
Post-operative Chronic Pain
Shifting Pain Modulation From Pro-to Anti-nociceptive
To create a data base that will facilitate the enrichment of the insights regarding post-operative pain development, and to identify those individuals with the potential to develop this kind of pain.
- Trial name
- NCT02672202
- Testing
- Duloxetine, Pregabalin
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Fibromyalgia
The Effect of Transcutaneous Posterior Tibial Nerve Stimulation in Patients With Fibromyalgia
This study aimed to investigate the effectiveness of posterior tibial nerve stimulation (PTNS) in reducing pain, improving quality of life, and decreasing disease severity in patients with fibromyalgia.
- Trial name
- NCT05937711
- Testing
- Transcutaneous Posterior Tibial Nerve Stimulation + Duloxetine 30 MG, Duloxetine 30 MG
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ilker Fatih Sari
Diabetic Neuropathies
A Study for the Treatment of Diabetic Peripheral Neuropathic Pain
The purpose of the study is to determine if duloxetine can help patients with painful diabetic neuropathy.
- Trial name
- NCT00552175
- Testing
- Duloxetine hydrochloride - 40 mg, Duloxetine hydrochloride - 60 mg
- Where
- 25 sites in Japan
- Volunteers
- 339 people
- Sponsor
- Eli Lilly and Company
Total Knee Arthroplasty
Does Duloxetine Reduce Sub-Acute Pain After Knee Arthroplasty?
We are investigating the impact of duloxetine ("Cymbalta"), a serotonin and norepinephrine reuptake inhibitor, on pain after total knee arthroplasty (TKA).
- Trial name
- NCT02005601
- Testing
- Duloxetine 60mg
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Hospital for Special Surgery, New York