Clinical trials: Enoxaparin
COVID-19, Pneumonia
Antithrombotic Therapy to Ameliorate Complications of COVID-19 (ATTACC)
Endothelial injury as a consequence of SARS-CoV-2 infection leads to a dysregulated host inflammatory response and activation of coagulation pathways.
- Trial name
- ATTACC (NCT04372589)
- Testing
- Heparin
- Where
- 60 sites in United States, Brazil and 2 more
- Volunteers
- 1,200 people
- Sponsor
- University of Manitoba
Liver Cirrhosis
Anticoagulation for Advanced Cirrhotic Patients After TIPS
Recent studies demonstrated that liver cirrhosis was associated with a hypercoagulability state. Besides, bacterial translocation plays an important role in the pathogenesis and complications in patients with decompensated…
- Trial name
- NCT03005444
- Testing
- Rivaroxaban
- Where
- 11 sites in China
- Volunteers
- 254 people
- Sponsor
- Air Force Military Medical University, China
Prevention of Arterial and Venous Thrombosis
A Clinical Study of SHR-2004 Injection in Preventing Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty
The purpose of the study is to evaluate the efficacy and safety of SHR-2004 in preventing venous thromboembolism after elective unilateral total knee arthroplasty.
- Trial name
- NCT06825416
- Testing
- SHR-2004 injection, Enoxaparin sodium injection
- Where
- 2 sites in China
- Volunteers
- 1,165 people
- Sponsor
- Beijing Suncadia Pharmaceuticals Co., Ltd
Sleep
Improving Sleep in the Neurology In-Patient Population
We aim to test multiple interventions to improve sleep for Neurology inpatients, including 1) a sleep-friendly order set, and 2) a sleep menu.
- Trial name
- I_SLEEP (NCT06094699)
- Testing
- Sleep friendly order set, Patient sleep menu
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- University of Pennsylvania
High Risk Pregnancy
Sildenafil Citrate Added to Low Molecular Weight Heparin and Low Dose Aspirin in High-risk Pregnancy
Anticoagulant therapy is indicated during pregnancy for the prevention and treatment of venous thromboembolism, systemic embolism in patients with mechanical heart valves and, in combination with aspirin, for the prevention of…
- Trial name
- NCT04110444
- Testing
- Sildenafil
- Where
- Egypt
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Covid19, Pneumonia
Effect of the Use of Anticoagulant Therapy During Hospitalization and Discharge in Patients With COVID-19 Infection
Viral infections provoke the systemic inflammatory response and cause an imbalance between the procoagulant and anticoagulant homeostatic mechanisms.
- Conditions
- Covid19, Pneumonia, Coagulation Disorder, Pulmonary Embolism
- Trial name
- NCT04508439
- Testing
- Enoxaparin
- Where
- Mexico
- Volunteers
- 130 people
- Sponsor
- Hospital Regional de Alta especialidad de Ixtapaluca
Fetal Growth Retardation, Prematurity
LMWH for Treatment of Early Fetal Growth Restriction (HepaGrowth)
Early fetal growth restriction (FGR) is associated with considerable fetal and neonatal morbimortality. Placental thrombosis, infarcts and hypercoagulability are frequently seen in these pregnancies, suggesting a role for the…
- Conditions
- Fetal Growth Retardation, Prematurity, Pre-Eclampsia
- Trial name
- HepaGrowth (NCT04762992)
- Testing
- subcutaneous Enoxaparin, standard of care
- Where
- Portugal
- Volunteers
- 12 people
- Sponsor
- Centro Hospitalar de Lisboa Central
Venous Thromboembolism, Obese Patients
Evaluation of Anti-Xa Activity in Patients With Severe Obesity After Subcutaneous Injection of Enoxaparin for Antithrombotic Prophylaxis at Two Different Sites.
To evaluate appropriateness of enoxaparin bioavailability at two different sites of subcutaneous administration (arms or abdomen) in primary or secondary prevention of thromboembolism in a population of patients with severe…
- Trial name
- EPOS (NCT07213713)
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hemodialysis
HENOX: Enoxaparine in Hemodialysis
Primary objective: To assess clinical efficacy of single bolus anticoagulation with Enoxaparin in chronic hemodialysis Secondary objective: To assess safety and tolerability by the number of spontaneously reported adverse events…
- Trial name
- NCT00347490
- Testing
- Enoxaparine
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Sanofi
Myocardial Infarction
Comparison of Primary PCI vs. Post-thrombolysis PCI as Reperfusion Strategies in STEMI
The conceptual hypothesis of this study is that primary angioplasty is superior to a combined strategy of immediate thrombolysis followed by routine angioplasty in patients with ST-segment elevation acute myocardial infarction…
- Trial name
- GRACIA4 (NCT02268669)
- Testing
- Reperfusion strategies
- Volunteers
- 1,444 people
- Sponsor
- GRACIA Group
TBI (Traumatic Brain Injury), VTE (Venous Thromboembolism)
Timing of VTE Prophylaxis in TBI
This study compares the efficacy and complication rates of early (24 hours) versus late (72 hours) VTE prophylaxis administration to TBI patients.
- Trial name
- NCT03081169
- Testing
- Enoxaparin Sodium 150 MG/ML Prefilled Syringe, Heparin
- Where
- United States
- Sponsor
- Loyola University
Recurrent Pregnancy Losses, Positive Anti Phospholipid Syndrome
Preconceptional Thromboprophylaxis in Recurrent PREGNANCY LOSSES Caused by Antiphospholipid Syndrome
Preconceptional use of low molecular weight heparin (enoxaparin) and aspirin in patient with recurrent miscarriages with positive anti phospholipid antibodies increase the implantation rate and the duration of pregnancy with low…
- Trial name
- NCT01661439
- Testing
- low molecular weight heparin (enoxeparine)
- Where
- Egypt
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Pregnancy
Evaluation of Pre-dose and Post-dose Anti-factor Xa Levels With Enoxaparin Use During Pregnancy
Venous thromboembolism is a condition that causes formation of blood clots in the body. It may have life threatening consequences if the leg veins, lungs or the brain blood vessels are involved.
- Trial name
- NCT00319176
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Venous Thromboembolic Disease, Deep Vein Thrombosis
Venous Thromboembolic Prophylaxis After Trauma: Three Times a Day Unfractionated Heparin Versus Twice a Day Enoxaparin
The rate of venous thromboembolic events in trauma patients at high risk for deep vein thrombosis and pulmonary embolism receiving low dose unfractionated heparin every 8 hours will be equivalent or less than a similar group of…
- Conditions
- Venous Thromboembolic Disease, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT01729559
- Testing
- 5000 Units unfractionated Heparin Q 8 hr, 30mg enoxaparin Q12 hr
- Where
- United States
- Volunteers
- 495 people
- Sponsor
- Scripps Health
Enoxaparin
Pharmacodynamic Equivalence of Ovine Enoxaparin to Lovenox®
This study is designed as a randomized, open-label, 2-way cross-over, single dose study with at least 7 days wash-out period. The objective of this study is to demonstrate the pharmacodynamic / pharmacokinetic equivalence of…
- Trial name
- NCT04402762
- Testing
- Ovine Enoxaparin, Enoxaparin Prefilled Syringe [Lovenox]
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Acute Coronary Syndrome
Enoxamed Study in the Treatment of Acute Coronary Syndromes
Because of their anti-Xa and ease of administration activity, the Low molecular weight heparin represent an attractive alternative to the unfractionated heparin.
- Trial name
- ENOXAMED (NCT02152423)
- Testing
- LOVENOX, ENOXAMED
- Where
- Tunisia
- Volunteers
- 50 people
- Sponsor
- University of Monastir
Multiple Myeloma
UARK 2005-01 Study of Velcade, Thalidomide, and Dexamethasone (VTD) With or Without Adriamycin® in Relapsed/Refractory Patients
The main goal of this study is to evaluate the effectiveness of the combination of these drugs, and whether they can be given safely together.
- Trial name
- NCT00111748
- Testing
- Velcade, Thalidomide, Dexamethasone
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Arkansas
Acute ST Elevation Myocardial Infarction
The Efficacy and Safety of rhTNK-tPA in Comparison With Alteplase(Rt-PA) as Fibrinolytic Therapy of Acute STEMI
This study is aiming to test the hypothesis that efficacy of rhTNK-tPA was not inferior to rt-PA with respect to the 30-day MACCE rates after fibrinolytic therapy for STEMI patients.
- Trial name
- NCT02835534
- Testing
- rhTNK-tPA, alteplase
- Where
- China
- Volunteers
- 818 people
- Sponsor
- CSPC Mingfule Pharmaceutical (Guangzhou) Co., Ltd.
Female , Infertility
Comparison Between Effect of Enoxaparin and Clopidogrel on Improving Pregnancy Rate in ICSI
Comparison between effect of enoxaparin and clopidogrel on improving pregnancy rate in ICSI
- Trial name
- NCT02696330
- Testing
- clopidogrel, enoxaparin
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Non ST Elevation Myocardial Infarction
Clinical Effects of Eptifibatide Administration in High Risk Patients Presenting With Non-ST Segment Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Urgent Coronary Artery Bypass Graft Surgery in Short- and Long-Term Follow-up
1. INTRODUCTION Through last couple of years the number of patients treated for acute coronary event without persistent ST segment elevation in ECG has been growing.
- Trial name
- NCT01863134
- Testing
- Eptifibatide
- Where
- 6 sites in United States, Poland
- Volunteers
- 140 people
- Sponsor
- Medical University of Silesia