Clinical trials: Etanercept
Juvenile Idiopathic Arthritis
Effective Dose of Etanercept in Patients Treated for Juvenile Idiopathic Arthritis
The purpose of this study is to determine the optimal dosage of etanercept in patients treated for idiopathic juvenile arthritis
- Trial name
- Etaplus (NCT02030613)
- Testing
- Blood test
- Where
- France
- Volunteers
- 126 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Plaque Psoriasis
Safety and Efficacy of Secukinumab Compared to Etanercept in Subjects With Moderate to Severe, Chronic Plaque-Type Psoriasis
This study will assess the safety and efficacy of secukinumab compared to placebo and etanercept in patients that have moderate to severe, chronic, plaque-type psoriasis.
- Trial name
- FIXTURE (NCT01358578)
- Testing
- secukinumab (AIN457), etanercept
- Where
- 152 sites in United States, Argentina and 21 more
- Volunteers
- 1,306 people
- Sponsor
- Novartis Pharmaceuticals
Rheumatoid Arthritis
Optimal Management of Rheumatoid Arthritis Patients Requiring Biologic Therapy
That anti-TNF therapy and rituximab therapy are equally effective in treating patients with rheumatoid arthritis who meet the eligibility criteria for biologic therapy in the British Society for Rheumatology guidelines, and have…
- Trial name
- ORBIT (NCT01021735)
- Testing
- etanercept or adalimumab, Rituximab
- Where
- 8 sites in United Kingdom
- Volunteers
- 302 people
- Sponsor
- University of Glasgow
Rheumatoid Arthritis
Standard Disease Activity Parameters and Step Activity in Patients With Rheumatoid Arthritis Receiving Etanercept
Data on activities of daily living in patients with rheumatoid arthritis are assessed mainly be the health assessment questionnaire (HAQ). The HAQ generates data by subjective variables.
- Trial name
- NCT01388608
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- University Hospital Muenster
Rheumatoid Arthritis
Long Term Efficacy, Safety and Immunogenicity of Enerceptan in Rheumatoid Arthritis ( GEMENE002 )
The purpose of this study is to asses the long term efficacy, safety and immunogenicity of ENERCEPTAN® in combination with Methotrexate for the treatment of patients with rheumatoid arthritis up to 104 weeks
- Trial name
- NCT03403140
- Testing
- Etanercept
- Where
- Argentina
- Volunteers
- 141 people
- Sponsor
- Gema Biotech S.A.
Metabolic Syndrome
Study of TNF-Antagonism in Metabolic Syndrome
This study investigates whether blockade of TNF will result in reduced inflammatory indices in patients with the metabolic syndrome
- Trial name
- NCT00409318
- Testing
- Etanercept
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Spondyloarthritis
Etanercept (Enbrel) in Undifferentiated Spondyloarthritis
The study has the aim to investigate the efficacy and safety of etanercept in patients with active undifferentiated spondyloarthritis (uSpA) over the period of 520 weeks.
- Trial name
- Enbrel_uSpA-2 (NCT01289730)
- Testing
- Etanercept
- Where
- 2 sites in Germany
- Volunteers
- 8 people
- Sponsor
- Charite University, Berlin, Germany
Diabetes Mellitus, Type I
Study of Islet Transplantation in Type 1 Diabetic Kidney Transplant Recipients
The purpose of the study is to learn if islet transplantation is an effective treatment for Type 1 diabetes in people who have had a kidney transplant.
- Trial name
- NCT00888628
- Testing
- Purified Pancreatic Islets, Etanercept
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Massachusetts General Hospital
Alzheimer's Disease
Short Term Efficacy and Safety of Perispinal Administration of Etanercept in Mild to Moderate Alzheimer's Disease
While the cause of AD is still unknown, evidence suggests it develops because of a complex series of events in the brain that occur over time.
- Trial name
- NCT01716637
- Testing
- Etanercept, Curcum.Luteol.Theaflav.Lip.Acid,FishOil,Quercet.,Resveratr.
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Life Extension Foundation Inc.
Spondylitis, Ankylosing
Prediction of the Answer to the Treatment by Biotherapies for Naive Spondyloarthritis by Combinatorial Analysis of Serum Biomarkers
The aim of this trial is the caracterisation of a predicting algorithm of the answering response for patients with etanercept treatment in spondyloarthritis disease.
- Trial name
- PRESA (NCT03033095)
- Testing
- Etanercept ® 50 mg
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Grenoble
Rheumatoid Arthritis
Rheumatoid Arthritis DMARD Intervention and UtilizationStudy
To systematically collect and document use patterns, effectiveness and safety of DMARD treatments currently used in the management of rheumatoid arthritis.
- Trial name
- NCT00116727
- Testing
- ENBREL®
- Volunteers
- 5,103 people
- Sponsor
- Amgen
End Stage Renal Disease
Safety and Efficacy Study of the Effect of Etanercept in Hemodialysis Patients
Etanercept is a novel anti-inflammatory agent currently used in patients with rheumatoid arthritis. We are examining whether Etanercept is effective in improving the nutritional status of hemodialysis patients as a consequence of…
- Trial name
- NCT00293202
- Testing
- Etanercept
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kaysen, George A., M.D., Ph.D.
Plaque Psoriasis
Study Evaluating Enbrel (Etanercept) in Adult Patients With Plaque Psoriasis
The purpose of this study is to investigate the incidences of adverse events for patients with plaque psoriasis treated with Enbrel under usual care settings.
- Trial name
- NCT00227240
- Where
- 2 sites in Germany
- Volunteers
- 753 people
- Sponsor
- Pfizer
Arthritis, Rheumatoid
Study Evaluating the Efficacy and Safety of Etanercept in Chinese Subjects With Rheumatoid Arthritis
The objective of this study is to compare in Chinese subjects with rheumatoid arthritis (RA) the efficacy and safety in this subject population of 50 mg once-weekly injections of etanercept versus placebo in subjects receiving…
- Trial name
- NCT00443950
- Testing
- Etanercept
- Where
- 6 sites in China
- Volunteers
- 150 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Psoriasis
An Observational Monocentric Study Investigating the Association Between Trough Serum Levels of Etanercept, Antibodies Towards Etanercept and Its Effectiveness in Psoriasis Patients
The purpose of this study is to investigate the association between trough serum levels of etanercept, antibodies towards etanercept and its effectiveness in psoriasis patients.
- Trial name
- DERM (NCT02322580)
- Testing
- etanercept
- Volunteers
- 56 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hidradenitis Suppurativa
Etanercept for Treatment of Hidradenitis
This study is being done to test a drug called etanercept (Enbrel®). Etanercept has been approved by the U.S. Food and Drug Administration (FDA) for the treatment of chronic moderate to severe plaque psoriasis (PsO), for use in…
- Trial name
- NCT00107991
- Testing
- etanercept
- Volunteers
- 15 people
- Sponsor
- University of Pennsylvania
Arthritis, Rheumatoid, Spondylitis, Ankylosing
Heart Function in Rheumatoid Arthritis and Ankylosing Spondylitis Pre and Post-TNF Blocker
The purpose of this study is to determine possible alterations in cardiac function in patients with Rheumatoid Arthritis and Ankylosing Spondylitis under anti-TNF therapy, without clinical heart disfunction at baseline, using…
- Trial name
- NCT01072058
- Testing
- TNF blockers (infliximab, adalimumab, etanercept)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo
Rheumatoid Arthritis, Psoriatic Arthritis
Effects of Biological Treatment on Blood Pressure and Endothelial Function in Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
The aim of this study is to evaluate the influence of anti tumor necrosis factor-alpha (TNF-α) treatment on blood pressure, endothelial function and immune cell phenotype in patients with rheumatoid arthritis, psoriatic arthritis…
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Hypertension
- Trial name
- NCT02132234
- Testing
- Etanercept, Adalimumab, Certolizumab
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Jagiellonian University
Rheumatoid Arthritis
A Proof of Concept and Dose Ranging Study in Patients With Rheumatoid Arthritis
This study is being carried out to investigate if AZD5672 is effective in treating Rheumatoid Arthritis (RA) and if so how it compares to placebo (a substance which does not have any action) and etanercept (a medicine already…
- Trial name
- ESCAPE (NCT00713544)
- Testing
- AZD5672, Etanercept
- Where
- 49 sites in Bulgaria, Colombia and 12 more
- Volunteers
- 373 people
- Sponsor
- AstraZeneca
Healthy
Safety and Pharmacokinetic Characteristics of HD203 Liq. in Healthy Subjects
The purpose of this study is compare the safety and pharmacokinetic characteristics of HD203 liquid with those of etanercept (enbrel) prefilled injection after subcutaneous injection.
- Trial name
- NCT01431404
- Testing
- Etanercept (Enbrel), HD203
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Hanwha Chemical