Clinical trials: Exercise Intervention
Healthy
Role of Endothelin-1 in Optic Nerve Head Blood Flow Regulation During Isometric Exercise in Healthy Humans
Autoregulation is defined as the ability of a vascular bed to adapt its vascular resistance to changes in perfusion pressure. In the eye, several studies have reported that retinal blood flow is autoregulated over a wide range of…
- Trial name
- NCT00915070
- Testing
- BQ-123, Physiological saline solution, Laser Doppler Flowmetry
- Where
- Austria
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
COPD
Long-term Effects of a 3-month Pedometer-based Program to Enhance Physical Activity in Patients With Severe COPD
Long-term evaluation of a coaching program which helps patients with severe COPD to increase their daily step count, in addition to usual care.
- Trial name
- NCT03114241
- Testing
- Intervention
- Where
- Switzerland
- Volunteers
- 74 people
- Sponsor
- University of Zurich
Cognitive Impairment, Cognitive Flexibility
The Effects of Single Exercise Sessions on Cognitive Flexibility and Brain Functional Connectivity in Older Adults With Cognitive Impairment
Objectives: To investigate the effects of different forms (physical and mental, aerobic and resistance) of single exercise on the cognitive flexibility and brain functional connectivity of elderly individuals with cognitive…
- Trial name
- NCT07623954
- Testing
- EXERCISE TRAINING, health education materials
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai University of Sport
Dysphagia, Oropharyngeal
The Efficacy of Tongue Exercises on Swallowing Function in the Elderly With Mild Cognitive Impairment
The purpose of this study is to explore the effects of tongue muscle strength and resistance exercises on dysphagia, tongue muscle strength, oral hygiene, repetitive saliva swallowing, nutrition, depression, and…
- Trial name
- NCT06490705
- Testing
- tongue resistance exercises, tongue strengthening exercises and tongue resistance exercises
- Where
- Taiwan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Chang Gung Medical Foundation
Obesity, Lifestyle-related Condition
Lifestyle Intervention in Preparation for Pregnancy (LIPP)
Studies evaluating lifestyle intervention in obese women during pregnancy have reported limited success in decreasing excessive gestational weight gain, and have failed to achieve the key outcome of breaking the obesity cycle and…
- Conditions
- Obesity, Lifestyle-related Condition, Macrosomia, Fetal
- Trial name
- NCT03146156
- Testing
- Lifestyle Intervention
- Where
- 4 sites in United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Mild Cognitive Impairment
The Impact of Physical Exercise on Working Memory in Elderly People With Mild Cognitive Impairment
Age-related cognitive decline has evolved into a global public health concern, with deteriorated executive function serving as its predominant manifestation.
- Trial name
- NCT07644156
- Testing
- Resistance band exercise intervention, Brisk walking intervention, Eight-Section brocade exercise intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai University of Sport
Functional Neurological Disorder
Body Signal Integration Training: A Case Series
The goal of this clinical trial is to learn about an intervention package in individuals with Functional Neurological Disorder (FND).
- Trial name
- NCT05941702
- Testing
- Body Signal Integration Training
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- University of Manchester
Low Back Pain
A Multi-Site Feasibility Trial of Embedded Emergency Department Physical Therapy
This is a multi-site feasibility trial of an embedded emergency department (ED) physical therapy care model for low back pain at two EDs in the Northwestern Medicine and University of Utah Health systems.
- Trial name
- FEED-PT (NCT07224945)
- Testing
- Embedded Emergency Department Physical Therapy, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Northwestern University
Chronic Disease Prevention
Evaluate Health Coaching Support in Technology-based Interventions for Meeting Health Goals
This was a pilot evaluation conducted to test procedures for a possible future trial and provide preliminary insights regarding whether text messages sent to Veterans could help support nutrition and/or physical activity health…
- Trial name
- Coaching (NCT04021472)
- Testing
- Text message
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Single Level Spinal Fusion, Discetomy
Integration of Mindfulness and Acupuncture After Spine Surgery
The Integration of Mindfulness and Acupuncture for individuals undergoing Spine Surgery (I-MASS) is a novel combination of integrative treatments to improve post-surgical recovery.
- Conditions
- Single Level Spinal Fusion, Discetomy, Laminectomy
- Trial name
- I-MASS (NCT06429072)
- Testing
- Mindfulness training, Acupuncture, Enhanced education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Duke University
Spinal Cord Injuries
Health Promotion and Cardiovascular Risk Reduction Among People With Spinal Cord Injury
This study is a controlled pragmatic implementation study in clinical practice, with a primary focus on cardiovascular risk reduction through adherence to behavioral interventions related to physical activity and healthy diet.The…
- Trial name
- NCT03689023
- Testing
- A controlled multimodal intervention
- Where
- Denmark
- Volunteers
- 97 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obesity (BMI > 35)
Preserving Muscle Mass During Incretin-Induced Weight Loss
Treatment with incretin-based obesity medications leads to clinically meaningful weight loss and reduced cardiometabolic risk. However, the weight lost includes not only adipose tissue but also skeletal muscle, which may impair…
- Trial name
- INCRETraIN (NCT07761923)
- Testing
- Unilateral Resistance Training
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Emotional Distress
Mindfulness Interventions and Emotional Distress: A Daily Study
This study hopes to explore whether the changes in rumination exhibited in Daily Diary mediates the effects of mindfulness intervention on alleviating emotional distress
- Trial name
- NCT06785259
- Testing
- Mindfulness Intervention for Emotional Distress(MIED)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University
Obesity, Compensated Cirrhosis
OPTIMIzing muScle Preservation in paTients wIth Cirrhosis
Patients with obesity and cirrhosis benefit from weight loss but are prone to sarcopenia (loss of muscle mass, strength, and function).
- Conditions
- Obesity, Compensated Cirrhosis, Sarcopenia
- Trial name
- OPTIMISTIC (NCT05367596)
- Testing
- Continuous Energy Restriction (CER), Alternate Day Modified Fasting (ADMF), Group Health Education Sessions
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center
160 Participants Aged 18-35 Years and Obese (BMI ≥30) Open to Men and Women of All Ethnicity
Glycemic Load & Resistance Training on Endothelial Function & Insulin Sensitivity
This project is prompted by the urgent public health need to identify novel strategies to prevent cardiovascular disease (CVD) and type 2 diabetes (T2D).
- Trial name
- GET FIT (NCT01755962)
- Testing
- Glycemic Load, Resistance Training
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Traumatic Brain Injury
TBI Rehabilitation and Activation in Veterans
This trial will evaluate the impact of a multicomponent program (TBI Rehabilitation and Activation in Veterans; TRAIN-Vets) on improving cognitive function over an 8-month trial period in older Veterans with traumatic brain…
- Trial name
- TRAIN-Vets (NCT06562127)
- Testing
- TRAIN-Vets, Health Education Control
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Northern California Institute of Research and Education
Orthopaedic Injury, Mindfulness
A 60-seconds Personalized Mindfulness Video Exercise for Patients With Orthopedic Illness
The purpose of this study is to determine within a randomized controlled trial the feasibility of a 60-second acceptance based mindfulness exercise for patients with musculoskeletal pain versus usual medical care.
- Trial name
- NCT03212105
- Testing
- 60 Second Video, Educational Brochure
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Massachusetts General Hospital
Teenager, Young Adult
Cognitive Remediation Therapy in Anorexia Nervosa
"Clinicians from the Maudsley (IoP, London, UK) have specifically tailored a cognitive remediation therapy (CRT) for treating Anorexia Nervosa (AN).
- Conditions
- Teenager, Young Adult, Hospitalized, Anorexia Nervosa (DSM-IV Revised Criteria)
- Trial name
- TreCogAM (NCT01772394)
- Testing
- Cognitive Remediation Therapy
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stage II Breast Cancer, Stage IIA Breast Cancer
Aerobic and Strength Training Exercise in Improving Fitness and Arm Health During and After Radiation Therapy in Patients With Stage II-III Breast Cancer
This randomized pilot phase I/II trial studies how well aerobic and strength training exercise works in improving fitness and arm health during and after radiation therapy consisting of regional nodal radiation in patients with…
- Conditions
- Stage II Breast Cancer, Stage IIA Breast Cancer, Stage IIB Breast Cancer, Stage III Breast Cancer
- Trial name
- NCT03102866
- Testing
- Best Practice, Exercise Intervention, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
To Assess the Impact of the HIT Intervention on Physiological Responses, To Assess the Role of a Secondary High School as a Setting for Promoting Healthy Eating and PA Behaviours
The Influence of a High Intensity Physical Activity Intervention on a Selection of Health Related Outcomes: An Ecological Approach
The purpose of this study is to determine whether a High Intensity exercise intervention can elicit cardiovascular disease protection in adolescents.
- Conditions
- To Assess the Impact of the HIT Intervention on Physiological Responses, To Assess the Role of a Secondary High School as a Setting for Promoting Healthy Eating and PA Behaviours, To Determine the Associations Between CVD Risk Factors at Baseline in 15 - 18 Year Old Youth
- Trial name
- NCT01027156
- Testing
- High Intensity Exercise
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of the West of Scotland
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