Clinical trials: Exercise Intervention
Depression
Spanish Intervention for Caregivers of Veterans With Stroke
This research study will test a problem-solving intervention for Spanish-speaking stroke caregivers that will be delivered over the telephone and online via the previously developed and nationally available Spanish version of the…
- Trial name
- RESCUE (NCT03142841)
- Testing
- RESCUE Problem Solving Intervention
- Where
- 4 sites in United States, Puerto Rico
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anxiety and Mood Disorders
Compassion Meditation for Older Adults
Some older Veterans with psychological distress may under-utilize mental health services due to perceived stigma of symptom-focused interventions.
- Trial name
- NCT03964246
- Testing
- Compassion Meditation (CM) intervention, Healthy Aging Psychoeducation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- VA Office of Research and Development
Pregnancy Related, Cardiovascular Risk Factor
Promoting Stretching Exercise to Reduce Cardiovascular Health Risk in Late Pregnant Women With Obesity
The purpose of this trial is to determine whether a stretching intervention is superior to a usual care control condition (moderate/vigorous activity 30 minutes daily, 5 days per week) for pregnant women from 27 to 37 gestational…
- Conditions
- Pregnancy Related, Cardiovascular Risk Factor, Obesity
- Trial name
- NCT04291560
- Testing
- Stretching Exercise Intervention
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- University of North Carolina, Chapel Hill
Weight Change, Body, Smoking Cessation
Efficacy of Two Novel Behavioral Post-cessation Weight Gain Interventions
The study aims to randomize 400 participants to 1 of 3 arms: a) a weight stability intervention prior to smoking cessation (Group 1); b) a weight loss intervention prior to smoking cessation (Group 2); or c) a self-guided weight…
- Trial name
- NCT03156660
- Testing
- Weight gain prevention (Group 1), Weight loss intervention (Group 2), Self-guided intervention (Group 3)
- Where
- United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Cardiovascular Diseases, Coronary Artery Disease
ISCHEMIA-Chronic Kidney Disease Trial
The purpose of the ISCHEMIA-CKD trial is to determine the best management strategy for patients with stable ischemic heart disease (SIHD), at least moderate inducible ischemia and advanced chronic kidney disease (CKD; estimated…
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- ISCHEMIA-CKD (NCT01985360)
- Testing
- Cardiac Catheterization, Coronary Artery Bypass Graft Surgery, Percutaneous Coronary Intervention
- Where
- United States
- Volunteers
- 777 people
- Sponsor
- NYU Langone Health
Obesity
TOSS Feasibility + Fitbit Community = Reduced Obesity in Older Black Women
The primary goal of this proposed physical activity (PA) intervention is to develop a realistic and an economical intervention to promote regular PA among older, overweight or obese Black women.
- Trial name
- NCT04114071
- Testing
- TOSS Feasibility + Fitbit Community = Reduced Obesity in Older Black Women
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cognitive Impairment, Mild, Cognitive Decline
Efficacy of a Multimodal Brain Health Intervention for Older African Americans
This study tests the feasibility, acceptability, and efficacy of a multimodal intervention (walking, social engagement, and reminiscence), including the use of wearable digital biomarkers, for cognitively healthy and mildly…
- Trial name
- SHARP (NCT04863378)
- Testing
- Walking conversational reminiscence
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Diastolic Heart Failure, Heart Failure, Congestive
PIE II: Pharmacological Intervention in the Elderly II
The purpose of this study is to examine whether spironolactone will improve exercise tolerance and quality of life in elderly patients with heart failure preserved ejection fraction (HFPEF).
- Trial name
- NCT00123955
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University
Diabetes Mellitus (DM)
Metatarsal Phalangeal Joint Deformity Progression - R01
The purpose of this research study is to determine the relationships between foot muscle, foot motion, and toe deformity. Results from this investigation will help the investigators to understand what contributes to foot…
- Trial name
- NCT02616263
- Testing
- Foot exercise, Shoulder exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Chronic Low Back Pain
Yoga for Veterans With CLBP
Chronic low back pain (CLBP) is a prevalent condition among VA patients, but many current treatment options have limited effectiveness.
- Trial name
- NCT02524158
- Testing
- Yoga Therapy for CLBP
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- VA Office of Research and Development
Obesity
Internet Assisted Obesity Treatment Enhanced With Financial Incentives
The investigators propose a randomized controlled trial to evaluate whether the addition of financial incentives to a high-quality, online behavioral weight loss intervention produces better weight losses than the online…
- Trial name
- iREACH3 (NCT02688621)
- Testing
- Internet Only, Internet + Incentives
- Where
- 2 sites in United States
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Rumination, Depression
Adolescent Mindfulness Mobile App Study (RCT)
Rumination involves focusing on negative emotions repeatedly and is a risk factor for developing depression, anxiety, and self-injury. These negative outcomes increase in adolescence.
- Conditions
- Rumination, Depression, Anxiety, Self-Injurious Behavior
- Trial name
- AMMASRCT (NCT03900416)
- Testing
- Mindfulness App
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Lawrence University
Obesity
Promoting Successful Weight Loss in Primary Care in Louisiana
The primary aim of this trial is to develop and test the effectiveness of a 24 month, patient-centered, pragmatic and scalable obesity treatment program delivered within primary care, inclusive of an underserved population.
- Trial name
- PROPEL (NCT02561221)
- Testing
- Lifestyle Counseling
- Where
- United States
- Volunteers
- 803 people
- Sponsor
- Pennington Biomedical Research Center
Obesity, Weight Loss
Utilizing Protein During Weight Loss to Impact Physical Function and Bone
This study is an ancillary study to the Utilizing Protein During Weight Loss to Impact Physical Function (UPLIFT) trial (NCT03074643) to evaluate the effects of diet composition (i.e., amount of protein and carbohydrate) during a…
- Conditions
- Obesity, Weight Loss, Diet Modification, Aging
- Trial name
- UPLIFT-Bone (NCT03819478)
- Testing
- Weight loss intervention months 0-6, Exercise intervention months 0-6, NutraBio™ CarboMax Supplement
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Wake Forest University Health Sciences
Soccer, Exercise
Effects of the FIFA11+ Warm-up Program on Speed, Agility, and Vertical Jump Performance in Adult Female Amateur Soccer Players
This study is being conducted for a master's dissertation. Our goal is to determine if there are physical performance benefits to performing the FIFA11+ soccer warm-up program in adult female soccer players over an eight week…
- Conditions
- Soccer, Exercise, Athletic Performance
- Trial name
- FIFA (NCT03683758)
- Testing
- FIFA11+, 'Usual' Soccer Warm-up
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Orthopedic Surgery, Older Adults
Perioperative Mental Health in Orthopedic Surgery
This Hybrid 1 Study will test the effectiveness of a bundled intervention comprised of behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing Orthopedic surgery…
- Conditions
- Orthopedic Surgery, Older Adults, Depression, Anxiety
- Trial name
- CPMH (NCT05697835)
- Testing
- Behavioral activation, Medication optimzation, Care as usual
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Washington University School of Medicine
Multiple Sclerosis
Physical Telerehabilitation in Veterans With Multiple Sclerosis
The primary objective of this study will be to assess the feasibility and patient acceptance of a Home Automated Telemanagement (HAT) system in multiple sclerosis patients.
- Trial name
- NCT02346734
- Testing
- Multiple Sclerosis Home Automated Telemanagement (MS HAT) system
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Maryland, Baltimore
Obesity
Research Intervention to Support Healthy Eating and Exercise
The primary aim of this study is to test the efficacy of a behavioral economics intervention for weight loss in adults from economically disadvantaged backgrounds.
- Trial name
- RISE (NCT04353258)
- Testing
- Behavioral Economics intervention (BE mHealth), Standard mHealth intervention (mHealth)
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- University of Connecticut
COVID-19 Infection
Breathing Techniques and Meditation for Health Care Workers During COVID-19 Pandemic
This phase I trial investigates breathing techniques and meditation for health care workers during COVID-19 pandemic. Breathing techniques and medication may help manage stress and improve lung health.
- Trial name
- NCT04482647
- Testing
- Media Intervention, Meditation Therapy, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Obesity, Weight Loss
Lifestyle Behavior Weight Loss Intervention
This lifestyle behavior intervention aims to weight loss in low-income overweight or obese mothers of young children through promotion of stress management, healthy eating, and physical activity.
- Trial name
- NCT04649047
- Testing
- Goal-oriented episodic future thinking
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ohio State University
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