Clinical trials: Exercise training, open to volunteers
Dementia, tDCS
The Efficacy of HD-tDCS-Augmented Step Training in Older Adults With Mild Dementia
Falls and mobility decline are major health concerns among older adults with dementia, often linked to deterioration in executive function and cognitive-motor control.
- Conditions
- Dementia, tDCS, Physical Exercise, Neuromodulation
- Trial name
- NCT07841145
- Testing
- Step training, active HD-tDCS
- Where
- Hong Kong
- Volunteers
- 68 people
- Sponsor
- The Hong Kong Polytechnic University
Traumatic Lower Limb Amputation, Fatigue
Effect of Adding Progressive Muscle Relaxation to Physical Therapy Program on Fatigue, Mobility and Stress Among Individuals With Traumatic Lower Limb Amputation in the Gaza Strip
Lower limb amputation is a life-altering condition with profound physical and psychological consequences, including fatigue, impaired mobility, stress, and asymmetrical weight-bearing.
- Conditions
- Traumatic Lower Limb Amputation, Fatigue, Mobility Impairment, Psychological Stress
- Trial name
- PMR-AMP (NCT07139145)
- Testing
- Progressive Muscle Relaxation + Standard Physiotherapy, Standard Physiotherapy
- Where
- Palestinian Territories
- Volunteers
- 60 people
- Sponsor
- Marah Radi
Depression
Mindfulness Training During Accelerated TMS for Depression
This NIH-funded single-arm pilot tests the feasibility, acceptability, and preliminary effects of embedding brief guided mindfulness practice (via the Waking Up smartphone app) into the inter-session intervals of clinically…
- Trial name
- NCT07369557
- Testing
- Guided Mindfulness Practice using a study created web app that links to the commercially available Waking Up app
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Gestational Hypertension, Preeclampsia (PE)
Postpartum CO Rehabilitation
Some women who develop high blood pressure during pregnancy, such as gestational hypertension or preeclampsia, may continue to have slightly or moderately high blood pressure after giving birth.
- Trial name
- NCT06920537
- Testing
- Postpartum Cardio-obstetric Rehabilitation Program
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Stroke, Upper Extremity Paresis
Virtual Reality Training Dose for Arm Recovery After Stroke: Clinical and Blood Biomarker Responses
The goal of this clinical trial is to learn whether adding virtual reality (VR) training to conventional rehabilitation improves arm movement in adults who had a stroke 6 to 24 months earlier, and whether VR training 5 days a…
- Trial name
- NCT07919301
- Testing
- Neuroforma virtual reality training, Conventional rehabilitation program, Home exercise program
- Volunteers
- 72 people
- Sponsor
- Kutahya Health Sciences University
ICU Delirium
Modified Hospital Elder Life Program at Intensive Care Unit
Delirium, a form of acute brain dysfunction, occurs in up to 81% of patients receiving mechanical ventilation in the intensive care unit (ICU).
- Trial name
- mHelp@ICU (NCT06054828)
- Testing
- mHELP@ICU
- Where
- Taiwan
- Volunteers
- 266 people
- Sponsor
- National Taiwan University Hospital
Hip Fractures
Rehabilitation After a Hip Fracture: the Effects of Dietary Protein and Exercise on Bone and Muscle Health and Quality of Life
Hip fractures often lead to functional limitations, loss of independence, weight loss and decreased well-being. Only half of the patients regain their functional level and 24% die within the following year.
- Trial name
- ProBUS (NCT07036341)
- Testing
- Protein-enriched diet, Progressive resistance exercise
- Where
- 2 sites in Netherlands
- Volunteers
- 102 people
- Sponsor
- Wageningen University
Anterior Cruciate Ligament Reconstruction Rehabilitation, Blood Flow Restriction (BFR) Training Effects
Effect of Blood Flow Restriction Rraining on Rehabilitation After Anterior Cruciate Ligament Reconstruction
Importance: Following anterior cruciate ligament reconstruction (ACLR), patients often experience quadriceps muscle weakness and atrophy, frequently leading to long-term complications.
- Trial name
- NCT07311031
- Testing
- Blood flow restriction training, Standard ACL rehabilitation
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital MAZ
Post-Traumatic Neck Pain, Whiplash-associated Disorders
StressModex for Post-Traumatic Neck Pain
Post-traumatic neck pain is a common consequence of traffic-related and other accidental injuries. While many individuals recover, a subgroup develops persistent pain, disability, and psychological distress.
- Trial name
- StressModex (NCT07824557)
- Testing
- StressModex plus Treatment as Usual
- Where
- 3 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- University of Southern Denmark
Cardiovascular Diseases (CVD), Coronary Disease
Impact of a Tailored Digital Intervention on Sedentary Behaviour and Physical Health in Long-term Cardiac Rehabilitation Patients
Sedentary behaviour (SB) is an independent cardiovascular risk factor that remains highly prevalent among individuals attending long-term cardiac rehabilitation (CR) programs, despite participation in regular supervised exercise.
- Conditions
- Cardiovascular Diseases (CVD), Coronary Disease, Heart Failure, Cardiac Rehabilitation
- Trial name
- REDUsit (NCT07910812)
- Testing
- Standard Cardiac Rehabilitation Care, Tailored behavioural counselling, Digital prompts
- Where
- Portugal
- Volunteers
- 64 people
- Sponsor
- University of Lisbon
Exercise, Primary Dysmenorrhea
Different Exercise Training Programs in University Students with Primary Dysmenorrhea
Dysmenorrhea is severe lower abdominal pain in women during menstruation. The pain is usually cramping and can radiate to the thighs or lower spine.
- Trial name
- NCT06860256
- Testing
- Basic Body Awareness Therapy, High Intensity Interval Training, Classic Exercise and Lifestyle Tips
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Hasan Kalyoncu University
Oesophageal Cancer, Gastric Cancer
Modulated Mid-frequency Whole-body Electromyostimulation and Nutritional Therapy in Gastrointestinal Cancer Patients
The purpose of this study is to assess the efficacy of modulated mid-frequency whole-body electromyostimulation (WB-EMS) combined with nutritional therapy in patients with gastrointestinal cancer.
- Conditions
- Oesophageal Cancer, Gastric Cancer, Duodenal Cancer, Colorectal Cancer
- Trial name
- MOMENT (NCT06414122)
- Testing
- mid-frequency whole-body electromyostimulation (WB-EMS), conventional exercise training, nutritional therapy
- Where
- Germany
- Volunteers
- 88 people
- Sponsor
- University of Cologne
Fatigue, Breast Cancer Female
Exercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore
The purpose of this research study is to investigate the acceptability, feasibility, and effectiveness of exercise therapy and cognitive behavioral therapy (CBT) in improving fatigue levels and breast cancer treatment adherence…
- Trial name
- NCT07116161
- Testing
- Graded Exercise Therapy Arm (GET), Experimental: Exercise Therapy (GET) plus Cognitive Behavioural Therapy (CBT)
- Where
- 4 sites in Singapore
- Volunteers
- 100 people
- Sponsor
- National Cancer Centre, Singapore
Dysphagia, Critical Illness
Optimizing Dysphagia Treatment Delivery in Acute Care: A Hybrid Efficacy Implementation Trial
This research study is investigating the efficacy and implementation of expiratory muscle strength training (EMST), standard of care dysphagia treatment, and intensive dysphagia treatment in critically ill adults in the acute…
- Trial name
- NCT07736105
- Testing
- Expiratory muscle strength training (EMST), Standard of Care Dysphagia Treatment, Intensive Dysphagia Treatment
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Vanderbilt University Medical Center
Neoplasms, Cancer Survivorship
Effectiveness of a Guided, Web-based, Stepped-care-approach to Cognitive Behavioral Therapy for Insomnia in Cancer Survivors
The goal of this multicenter randomized clinical trial is to develop and evaluate a web-based stepped-care approach to Cognitive Behavioral Therapy for Insomnia (CBT-I), specifically tailored to adult cancer survivors…
- Conditions
- Neoplasms, Cancer Survivorship, Insomnia
- Trial name
- eNightfall (NCT07876661)
- Testing
- Stepped-care Cognitive Behavioral Therapy for Insomnia, Standard web-based Cognitive Behavioral Therapy for Insomnia, Control arm - Care as usual with sleep hygiene leaflet
- Where
- Belgium
- Volunteers
- 140 people
- Sponsor
- Vrije Universiteit Brussel
Exercise Adherence
Adherence to Different Exercise Interventions
Only 50% of sedentary adults that start an exercise training program adhere to the program after 6 months. Exercise variety may improve adherence.
- Trial name
- NCT06024577
- Testing
- Walking, Variety, Progressive
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo
Multiple Sclerosis, Aging
Skeletal Muscle Aging and Responsiveness in Aged People With MS
The purposes of this study are to: 1) compare baseline muscle and cardiovascular health in older individuals (>60 years old) diagnosed with MS to age-matched people without MS, 2) determine muscle and whole body changes to an…
- Trial name
- MS-M3AX (NCT07500727)
- Testing
- Exercise trial consisting of both cardiovascular and strength training
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oklahoma Medical Research Foundation
Chronic Kidney Disease
Analysis of Effects of High-intensity Physical Exercise in Subjects With Dialyzed Chronic Kidney Disease and in Conservative Treatment
This study aims to analyze the effects of physical activity in patients with chronic kidney disease undergoing dialysis or conservative treatment.
- Trial name
- TONE (NCT07438002)
- Testing
- Exercise, control
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Stroke, Aphasia
Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits
The goal of the proposed project is to test the effectiveness of a novel hybrid approach to treatment of reading disorders after stroke, in which exercise training will be used in combination with a targeted reading treatment.
- Conditions
- Stroke, Aphasia, Reading Disorder
- Trial name
- NCT06213272
- Testing
- Phono-Motor Therapy, Aerobic Exercise Training (AET), Stretching
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Kessler Foundation
Patellofemoral Pain Syndrome
Core Stability Exercises Versus Proprioceptive Training on Pain and Function in Patients With Patellofemoral Pain Syndrome
This study will be conducted to investigate the effect of core stability exercises versus proprioceptive training in patients with patellofemoral pain syndrome.
- Trial name
- PFPS (NCT07664566)
- Testing
- Core Stability Exercises, Proprioceptive Training, traditional therapy
- Volunteers
- 63 people
- Sponsor
- Cairo University
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