Clinical trials: Experimental
Spina Bifida, Cerebral Palsy
Grand Valley State University (GVSU) Skills on Wheels
Manual wheelchairs (MWCs) are widely used by children with physical disabilities, yet many of these children are unable to use their wheelchair independently. Instead, they depend on others to push them.
- Conditions
- Spina Bifida, Cerebral Palsy, Genetic Disease, Spinal Cord Injuries
- Trial name
- NCT05339932
- Testing
- Manual Wheelchair Skills Training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Grand Valley State University
Shoulder Pain, Hemiplegia
Shoulder Passive Range of Motion and Positioning Exercise on Hemiplegic Stroke Patients
Several factors associated with the hemiplegic shoulder pain after stroke includes rotator cuff injury, bicipital tendonitis, impingement, spasticity, limited external rotation of shoulder joint, adhesive capsulitis, shoulder…
- Conditions
- Shoulder Pain, Hemiplegia, Stroke, Rotator Cuff Injury
- Trial name
- NCT03045432
- Testing
- video-teaching, oral-teaching, regular rehabilitation program
- Volunteers
- 104 people
- Sponsor
- Chang Gung Memorial Hospital
Epidural Anesthesia, Shivering
The Effect of Oral Pregabalin on Epidural-induced Shivering and Epidural Characteristics
Background: The previous reports tried to reduce shivering and improve neuroaxial anesthesia characteristics by the systemic use of different drugs.
- Trial name
- NCT03721432
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 77 people
- Sponsor
- Beni-Suef University
Chronic Obstructive Pulmonary Disease (COPD), Spirometry
Comparing Ultrasonic and Conventional Spirometry in Chronic Respiratory Disease
This study compares a handheld ultrasonic spirometer with a standard hospital spirometer in adults with chronic respiratory diseases. Each participant will complete lung function tests using both devices.
- Trial name
- NCT07447232
- Testing
- Spirometer
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Fu Jen Catholic University
Cancer Survivors
Cancer-related Fatigue and Symptom Clusters - Effects of Virtual, Imagined and Real-life Nature-based Therapy in Cancer Survivors
This is a randomized, controlled, bicenter trial comparing the effects on symptoms and quality of life in cancer survivors. Three nature-based therapies will be compared with a wait-list group.
- Trial name
- FOREST (NCT06931132)
- Testing
- Real-life forest bathing, Simulated FOREST bathing (Virtual Reality), Imaging FOREST bathing
- Where
- 2 sites in Germany
- Volunteers
- 172 people
- Sponsor
- Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)
Platelet Reactivity
Ticagrelor and Clopidogrel on Platelet Aggregation in Clopidogrel Resistance's Patients With CHD
The study sought to observe the effects of optimal dose of ticagrelor（90 mg qd）ticagrelor and double standard-dose clopidogrel on platelet reactivity in coronary heart disease patients with high on-treatment platelet reactivity…
- Trial name
- NCT03614832
- Testing
- Ticagrelor 90 mg, Clopidogrel 150 mg
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Relapsed or Refractory Hematologic Malignancies
A Clinical Study of SCTC21C in Participants With CD38+ Hematologic Malignancies
The purpose of this study is to evaluate the safety and efficacy of SCTC21C in patients with CD38+ hematologic malignancies
- Trial name
- NCT06252298
- Testing
- SCTC21C
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Sinocelltech Ltd.
Prostate Cancer, Colorectal Cancer
Impact of Exercise on Mitochondria in Cancer Patients.
The aim is to investigate the impact of prostate and colorectal cancer on mitochondrial quantity and quality along with muscle mass and function and whether this can be modified through the use of a home-based short-term exercise…
- Trial name
- ICCE-Mito (NCT04558398)
- Testing
- Resistance exercise training, High-intensity interval training
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Nottingham
Locally Advanced Lung Cancer; Metastatic Lung Cancer
Anti-PD-1 in Combination With Chemotherapy as First-Line Treatment to Lung Cancer
This is a Phase II, open-label, 4-cohort study of the monoclonal antibody BGB-A317 in combination with standard platinum-based chemotherapy in participants with advanced NSCLC or SCLC.
- Trial name
- NCT03432598
- Testing
- Tislelizumab, Paclitaxel, Gemcitabine
- Where
- 7 sites in China
- Volunteers
- 54 people
- Sponsor
- BeiGene
mHealth
VR-3D Movie-based Education
Atrial fibrillation (AF), which is the most common cardiac arrhythmia in adults, is associated with a high risk of stroke and other thromboembolic complications.
- Trial name
- NCT03104231
- Testing
- three-dimensional (3D) movie
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Warsaw
Hemodialysis
Effect of Whole Body Vibration on Walking Performance in Elderly Hemodialysis Patients
The purpose of this study is to evaluate the efficacy of whole body vibration for 12 weeks on walking performance in elderly hemodialysis patients.
- Trial name
- NCT04774731
- Testing
- Whole Body Vibration
- Where
- Japan
- Volunteers
- 98 people
- Sponsor
- Osaka University
Infections - Bacterial, Pneumonia - Bacterial
Use of Mobile Phones for Thermal Imaging of the Chest to Save Lives of Children With Pneumonia in Nagpur, India
The purpose of this study is to see if thermal images can be used instead of a chest x-ray to diagnose bacterial pneumonia in children with signs and symptoms of pneumonia in Nagpur, India.
- Trial name
- NCT02381431
- Testing
- FLIR ONE
- Where
- India
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Peritoneal Carcinomatosis
Pilot Study on Intra-abdominal Photodynamic Diagnosis in Peritoneal Carcinosis
The study would examine by hypericin-supported Fluoreszenzlaparoskopy in terms of tumor size, number and location of the combination of photodynamic diagnosis (PDD) and therapy (PDT) with regard to the detection of peritoneal…
- Trial name
- Hypericin-PDT (NCT02840331)
- Testing
- St. John's Wort, Photodynamic diagnostic and therapy
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital Tuebingen
Prostate Cancer
Quality of Life Study Using Gabapentin Versus Venlafaxine in Treating Hot Flashes in Patients With Prostate Cancer
The purpose of this study is to assess the change in quality of life over a 6 month period between gabapentin and venlafaxine in men with prostate cancer treated for hot flashes related to androgen deprivation therapy.
- Trial name
- NCT01533753
- Testing
- Gabapentin, Venlafaxine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Wisconsin, Madison
Neonatal Distress
Caesarean and Corticotherapy
Comparison of two randomized group : caesarean section planned at 38 weeks after 2 antenatal injections of 12 mg of betamethasone 48 h before. caesarean section planned at 39 weeks without corticosteroid.
- Trial name
- NCT00446953
- Testing
- betamethasone
- Where
- 5 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Hodgkin's Disease, Lymphoma
Alemtuzumab (Campath-1H) Monoclonal Antibody in Patients With Relapsed and Resistant Classical Hodgkin's Disease
Primary Objective: To determine the safety and efficacy of Campath-1H (Alemtuzumab) in patients with relapsed and resistant classical Hodgkin's lymphoma. Secondary Objectives: 1.
- Trial name
- NCT00129753
- Testing
- Alemtuzumab (Campath-1H)
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Multiple Sclerosis
Testosterone Treatment for Multiple Sclerosis
Since men are less likely to develop multiple sclerosis, the hypothesis was that testosterone might be protective in MS. Men with MS for followed untreated for 6 months, followed by a 12 month treatment period with Androgel.
- Trial name
- NCT00405353
- Testing
- Androgel 10 grams of gel containing 100 mg of testosterone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Los Angeles
Major Depressive Disorder
Efficacy, Safety and Tolerability of Agomelatine in the Prevention of Relapse of Major Depressive Disorder
This study will demonstrate the efficacy of agomelatine (AGO178) 25 mg and 50 mg in the prevention of relapse in patients with Major Depressive Disorder (MDD).
- Trial name
- NCT00467402
- Testing
- agomelatine
- Where
- 78 sites in United States
- Volunteers
- 644 people
- Sponsor
- Novartis
Chronic Obstructive Pulmonary Disease
Combinaison of Virtual Reality and Rehabilitation to Improve Muscle Function, Exercise Tolerance, Exertional Symptoms and Dyspnea in Patients With Chronic Respiratory Disease: a Randomized Cross-over Trial
Chronic respiratory diseases, such as Chronic Obstructive Pulmonary Disease (COPD), are a leading cause of death globally. These diseases not only contribute significantly to mortality but also lead to a decline in physical…
- Trial name
- OVERMUSCLED (NCT06811402)
- Testing
- virtual reality
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Telerehabilitation, COPD
Long-term Home-based Exercise for Patients With COPD: the COPDtoParis Project
This randomised controlled trial (RCT) aims to investigate the effect of long-term, interactive home-based cycle-exercise on patients with Chronic Obstructive Pulmonary Disease (COPD) after a COPD exacerbation requiring…
- Conditions
- Telerehabilitation, COPD, Quality of Life, Mobility Limitation
- Trial name
- COPDtoParis (NCT06235502)
- Testing
- Home-based cycle-exercise for COPD patients, Standard of Care
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aalborg University Hospital
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