Clinical trials: Experimental
Accidental Fall
Merging Attentional Focus and Balance Training to Reduce Fall Risk in Older Adults
Approximately 15 million older adults fall every year in the United States and fall prevention programs have only been moderately successful in arresting fall rates.
- Trial name
- NCT03776201
- Testing
- Balance Training
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of North Carolina, Greensboro
Type 2 Diabetes
Vildagliptin Versus Liraglutide - Patient Preference After Receiving Both Medications
Dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagonlike peptide-1 (GLP-1) mimetics or analogs, which rely on the gastrointestinal hormones that are part of the incretin system for the treatment of T2DM, provide a therapeutic…
- Trial name
- PREFER (NCT01518101)
- Testing
- Vildagliptin/ Metformin, Liraglutide, Metformin
- Where
- 8 sites in Germany
- Volunteers
- 62 people
- Sponsor
- Novartis Pharmaceuticals
Gastric Cancer, Chemotherapy Effect
Sintilimab Combined With Modified FLOT Regimen in the Treatment of Metastatic Gastric Cancer
This is a prospective, one-arm, single-center phase II study. The objective was to evaluate the efficacy and safety of domestic PD-1 antibody Sintilimab combined with modified FLOT regimen in the treatment of metastatic gastric…
- Conditions
- Gastric Cancer, Chemotherapy Effect, Immune Checkpoint Inhibitor
- Trial name
- NCT05982301
- Testing
- Sintilimab, paclitaxel-albumin, oxaliplatin, 5-FU
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Fudan University
Urethra Injury, Rectal Cancer
Validation of ICG to Identify the Urethra During Rectal Surgery
This is an open-label feasibility study utilising direct instillation of ICG into the urethra during surgery for low rectal cancers. The trial involves a single intervention taking place during the patient's operation.
- Conditions
- Urethra Injury, Rectal Cancer, Surgery
- Trial name
- NCT03204201
- Testing
- Indocyanine Green Solution
- Where
- United Kingdom
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Healthy Aging, Health Care Utilization
Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 1
This study consists of three aims focused on examining the feasibility of adding the Geriatric Resources and Assessment for the Care of Elders (GRACE) model to structured Annual Wellness Visits (AWVs) to improve patient and…
- Conditions
- Healthy Aging, Health Care Utilization, Health-Related Behavior
- Trial name
- SPIRE1 (NCT06287801)
- Testing
- Annual Wellness Visit, Geriatric Resources and Assessment for the Care of Elders
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Massachusetts General Hospital
Safety and Tolerability
PK and PD Profile of Dance 501 in Healthy, Non-diabetic Subjects With Mild to Moderate Asthma or COPD
This will be a randomized, open-label, active-controlled, single dose crossover study with either three or four treatment periods.
- Trial name
- NCT03307512
- Testing
- inhaled human insulin, Insulin Lispro (Humalog U-100)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dance Biopharm Inc.
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
Acalabrutinib in Combination With Venetoclax or Obinutuzumab for the Treatment of Treatment-naive Chronic Lymphocytic Leukemia
This phase II trial tests whether acalabrutinib in combination with venetoclax or obinutuzumab works to shrink tumors in patients with treatment-naive chronic lymphocytic leukemia .
- Trial name
- NCT05336812
- Testing
- Acalabrutinib, Obinutuzumab, Venetoclax
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Health Care Utilization, Health Care Seeking Behavior
Arogya Sangama: 3 Way Partnership of People, Providers, and Panchayat for Health
This is a two-year pilot project in the Raichur and Chamarajanagar districts of Karnataka, India aiming to enhance the overall performance of primary health systems, including service utilization, quality, and responsive care…
- Conditions
- Health Care Utilization, Health Care Seeking Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT06224712
- Testing
- Arogya Sangama
- Where
- 2 sites in India
- Volunteers
- 4,160 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Cancer
eSMART Trial to Evaluate ASyMS
Chemotherapy may cause distressing symptoms which can impact on patients' quality of life. Chemotherapy is frequently given on an outpatient basis therefore patients are often required to manage the symptoms they experience at…
- Trial name
- NCT02356081
- Testing
- ASyMS intervention Group
- Where
- 11 sites in Austria, Greece and 3 more
- Volunteers
- 829 people
- Sponsor
- Louise McKean
Neoplasms
Feasibility of an Advance Care Planning Intervention
Advanced Cancer patients hospitalized in a Cancer center inpatient unit have a dismal prognosis. Palliative Care interventions have shown multiple benefit for those patients, regarding quality of life, symptom management, illness…
- Trial name
- PREVOIR (NCT06149312)
- Testing
- Advance Care Planning Intervention
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Institut de cancérologie Strasbourg Europe
Acne Vulgaris, Medical Education
AI-Generated Acne Vulgaris Learning Material Study
This comparative educational intervention study evaluated the educational effectiveness of artificial intelligence-generated patient information material on acne vulgaris among early-year medical students.
- Trial name
- NCT07652112
- Testing
- Artificial Intelligence-Generated Acne Vulgaris Educational Material, Turkish Dermatology Association Acne Vulgaris Educational Material
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Hasan Durmuş
Hypereosinophilic Syndrome, Systemic Mastocytosis
Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes
This trial is for various types of malignancies which may depend on certain enzymes (tyrosine kinases) for growth. The objective of this study is to assess to what extent imatinib mesylate blocks these enzymes and to assess the…
- Conditions
- Hypereosinophilic Syndrome, Systemic Mastocytosis, Chronic Myelomonocytic Leukemia, Dermatofibrosarcoma
- Trial name
- NCT00171912
- Testing
- imatinib mesylate
- Where
- Australia
- Volunteers
- 38 people
- Sponsor
- Novartis Pharmaceuticals
Obesity
Weight Management Skills in African American Outpatients
Our long-term goal is to identify new insights about effective approaches to obesity management and related lifestyle changes in African Americans and about factors that enhance or limit the response to specific treatment…
- Trial name
- SHARE (NCT00146081)
- Testing
- Weight Management
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Pennsylvania
Vitamin D Deficiency
Physical Exercise and Diet Management in Vitamin D Deficient Females
The purpose of this study was to determine if home based physical exercises protocol and Diet management has an effect on functional performance and depression level related to vitamin D deficiency in females.
- Trial name
- NCT06114381
- Testing
- Home Based Physical Exercise, Vitamin D3 Supplements, Diet Management
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Badr University
Osteoporosis, Obesity
Breastfeeding and Exercise for Healthy Infants and Postpartum Moms Too!
Approximately 8 million American women suffer from osteoporosis, and one out of every two women over the age of 50 will have an osteoporotic-related fracture in their lifetime (42).
- Conditions
- Osteoporosis, Obesity, Weight Loss
- Trial name
- BEHIP (NCT00966381)
- Testing
- Exercise and weight loss intervention
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Acute Myeloid Leukemia
Study of Venetoclax in Combination With Azacytidine in AML Patients Selected Using Ex Vivo Drug Sensitivity Screening
This is a multi center two-stage, two-arm, open label phase II study of venetoclax in combination with azacytidine in acute myeloid leukemia patients selected for therapy with ex vivo venetoclax sensitivity screening.
- Trial name
- VenEx (NCT04267081)
- Testing
- Venetoclax
- Where
- Finland
- Volunteers
- 104 people
- Sponsor
- Helsinki University Central Hospital
Plaque Psoriasis
Study of Efficacy and Safety of HLX03 in Subjects With Moderate to Severe Plaque Psoriasis
This is a multicenter, randomized, double-blind, positive drug parallel-group controlled clinical study in China to evaluate efficacy, safety, tolerability and immunogenicity of HLX03 and adalimumab (Humira) in subjects with…
- Trial name
- NCT03316781
- Testing
- HLX03, adalimumab
- Where
- China
- Volunteers
- 262 people
- Sponsor
- Shanghai Henlius Biotech
Infection
Far-UVC and Infections in Long-term Care Facilities
Background Elderly residents in long-term care (LTC) facilities are highly susceptible to infections, often leading to hospitalizations and placing significant strain on the healthcare sector.
- Trial name
- NCT07511881
- Testing
- Far-uvc (222 nm), Standard Care (Treatment as Usual)
- Where
- Denmark
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Vejle Hospital
Musculoskeletal Diseases
Disjunction Between Patient Narrative and Formulaic Thinking in the Doctor
This study is seeking whether giving or not giving a clinician a card with talking points in the form of a checklist about the patient's story affects the patients care experience or not
- Trial name
- NCT05401981
- Testing
- Story checklist
- Where
- 5 sites in United States
- Sponsor
- University of Texas at Austin
Prader-Willi Syndrome, Resistance Training
Effects of Progressive Elastic Band Resistance Training
Abnormal body composition with increased body fat mass and decreased lean body mass has been found in adults with Prader-Willi syndrome (PWS), contributing to reduced physical capacity and impairment.
- Trial name
- NCT03565081
- Testing
- PWS elastic band training group
- Volunteers
- 6 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.