Clinical trials: Experimental, completed
Scalp Psoriasis
BE Study of Calcipotriene Hydrate and Betamethasone Dipropionate Topical Suspension in the Treatment of Scalp Psoriasis
This study will be conducted to evaluate the therapeutic bioequivalence of a TEST formulation of calcipotriene hydrate and betamethasone dipropionate topical suspension 0.005%/0.064% to the RLD.
- Trial name
- NCT03122353
- Testing
- Calcipotriene and betamethasone suspension, Taclonex
- Where
- 34 sites in United States
- Volunteers
- 699 people
- Sponsor
- Tolmar Inc.
Schizophrenia
Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Acute Schizophrenia
The purpose of this study is to explore changes in efficacy, cognitive functioning, and safety of flexibly-dosed Brexpiprazole monotherapy in subjects with acute schizophrenia
- Trial name
- NCT02054702
- Testing
- Brexpiprazole, Aripiprazole
- Volunteers
- 97 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Acute Myeloid Leukemia (AML)
Remote Outpatient Temperature Monitoring for Early Detection of Febrile Neutropenia After Chemotherapy
Febrile neutropenic patients are at high risk for developing sepsis and other infections which often necessitates acute admission to the Intensive Care Unit (ICU) and are associated with high mortality.
- Trial name
- REMEDY (NCT04081753)
- Testing
- Remote monitoring of temperature
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Augusta University
Interpersonal Psychotherapy, Polycystic Ovary Syndrome
Interpersonal Psychotherapy in Adolescents With Polycystic Ovary Syndrome
The main purpose of this study is to find out whether taking part in a group-based interpersonal psychotherapy (IPT) program designed to improve mood and lessen stress in girls with PCOS will improve depression, unhealthy eating…
- Trial name
- IPAP (NCT06056453)
- Testing
- Interpersonal Psychotherapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Influenza Immunization
Study With Quadrivalent Recombinant Influenza Vaccine (RIV4) in Participants 9 Through 49 Years of Age.
The purpose of this study was to demonstrate the non-inferiority (NI) of the HAI immune response of RIV4 in participants aged 9 to 17 years vs participants aged 18 to 49 years and to describe the immunogenicity and safety profile…
- Trial name
- NCT05513053
- Testing
- Quadrivalent Recombinant influenza vaccine (RIV4) season/2022-2023/NH
- Where
- 35 sites in United States, Czechia and 2 more
- Volunteers
- 1,308 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Healthy
Effects of Divalproex Sodium on Food Intake, Energy Expenditure, and Posture Allocation
The purpose of the proposed study is to identify the mechanisms responsible for the weight gain associated with Depakote treatment, and to identify methods to prevent and treat weight gain in people taking Depakote.
- Trial name
- VPA (NCT00287053)
- Testing
- divalproex sodium
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Antiseptic, Anesthesia, Local
The Effects of Low Viscosity Chloroprocaine Ophthalmic Gel 3% on the Bactericidal Action of Povidone-Iodine
To evaluate if Iheezo's (chloroprocaine 3%) gel vehicle acts as a barrier on the ocular surface, potentially blocking the bactericidal action of povidone-iodine.
- Trial name
- NCT05934253
- Testing
- Chloroprocaine ophthalmic gel 3%
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Harrow Inc
Healthy Participant
A Study to Learn How the Study Medicine Called Ibuzatrelvir is Taken up Into the Blood in Healthy Chinese Adults
A study to learn how the study medicine called Ibuzatrelvir is taken up into the blood in healthy Chinese adults.
- Trial name
- NCT07235137
- Testing
- Ibuzatrelvir
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Vegetable Intake After Weaning With Vegetables or Fruits, Fruit Intake After Weaning With Vegetables or Fruits
Mum Can I Have Vegetables Again? Development of Vegetable Preferences
Rationale: Despite the health benefits, children's consumption of vegetables is below the recommendations. Most human food preferences are learned through mere exposure, imitation, and conditioning principles.
- Trial name
- VaVo (NCT01858337)
- Testing
- green beans group, Artichoke group, Apple group
- Where
- Netherlands
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Relaxation Exercises and Training After Cesarean Section
Effects of Progressive Relaxation Exercises and Planned Training After Cesarean Section on Pain, Anxiety and Comfort
Effects of Progressive Relaxation Exercises and Planned Training after Cesarean Section on Pain, Anxiety and Comfort
- Trial name
- NCT07384637
- Testing
- Progressive Relaxation Exercise group, Planned Education group
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Attention Deficit Hyperactivity Disorder (ADHD), Binge-Eating Disorder Disorder
Study of the What the Body Does to the Drug in Subjects With Mild, Moderate, and Severe Liver Dysfunction
Study of the what the body does to the drug in subjects with mild, moderate, and sever liver dysfunction (not working properly)
- Trial name
- NCT02795637
- Testing
- dasotraline
- Where
- 5 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sumitomo Pharma America, Inc.
Hernia, Inguinal, Cryptorchidism
The Effect of Induction Technique on Postoperative Pain and Agitation
The objective of this study was to determine (a) whether patients anesthetized with intravenous propofol have less pain compared with sevofluorane for paediatric inguinal hernia and undescended testis operations and (b) whether…
- Trial name
- NCT02110745
- Testing
- Sevofluorane, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Mustafa Kemal University
Acute Pain
A Dose-ranging Study to Evaluate Efficacy and Safety of VX-150 in Subjects With Acute Pain Following Bunionectomy
This study will evaluate the dose-response relationship and safety of VX-150 in treating acute pain following bunionectomy.
- Trial name
- NCT03764072
- Testing
- VX-150
- Where
- 6 sites in United States
- Volunteers
- 250 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Healthy, Pharmacokinetics of ASP1941
A Study to Investigate the Effect of Food on the Absorption, Distribution and Elimination of ASP1941
This study is to investigate the effect of food on the pharmacokinetics, the pharmacodynamics and safety of ASP1941 after administration of ASP1941 in healthy non-elderly adult male subjects.
- Trial name
- NCT01674777
- Testing
- ASP1941
- Where
- Japan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Growth Hormone, EndoSeal MTA
Evaluation of the Efficacy of Growth Hormone, EndoSeal MTA Sealer, and Their Combination on Healing of Periapical Pathosis
This study aimed to evaluate the effect of growth hormone, EndoSeal MTA sealer, and their combination on Healing of Periapical Pathosis.
- Conditions
- Growth Hormone, EndoSeal MTA, Periapical Pathosis
- Trial name
- NCT06433375
- Testing
- Growth hormone application, Root canal treatment
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Induction of Ovulation, PCO - Polycystic Ovaries
Sodium-Glucose Co-Transporter-2 Inhibitors as Adjuvant Therapy With Letrozole in Induction of Ovulation in Women With Polycystic Ovarian Syndrome
The aim of the study is to assess the efficacy of adjuvant therapy dapagliflozin, metformin as monotherapy and combination of both in comparison to control group in induction of ovulation with letrozole in women PCOS, focusing…
- Trial name
- SGLT-2/PCOS (NCT07589075)
- Testing
- Metformin 1000 mg Oral Tablet, Dapagliflozin 10 MG Oral Tablet [Farxiga], Combined Dapagliflozin-Metformin 5/1000mg
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Advanced Solid Tumors
IPH5201 as Monotherapy or in Combination With Durvalumab +/- Oleclumab in Subjects With Advanced Solid Tumors.
The purpose of this study is to assess the safety and tolerability and to determine the dose of IPH5201 that can be used as monotherapy or in combination with durvalumab +/- oleclumab in subjects with advanced solid tumors.
- Trial name
- NCT04261075
- Testing
- IPH5201, durvalumab, oleclumab
- Where
- 8 sites in United States, France and 2 more
- Volunteers
- 57 people
- Sponsor
- MedImmune LLC
Acute Cerebral Stroke Within 12 Hours for the First Time
Dl-3-n-butylphthalide and Cerebrolysin Treatment in Acute Ischemic Stroke
The investigators conducted a randomized, double-blind, trial enrolled 60 patients within 12 hours of acute ischemic stroke (AIS) in China.
- Trial name
- NCT02149875
- Testing
- Dl-3-n-butylphthalide, Cerebrolysin
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shanghai 6th People's Hospital
Prostate Cancer
BIOPROP20: Biologically Optimised IMRT for Prostate Radiotherapy Hypofractionated Radiotherapy With Intra-prostatic Boosts to Tumour Nodules in Men With Intermediate and High Risk Prostate Cancer
High dose radiotherapy is a very effective treatment for prostate cancer. However, there is an increased risk of side effects compared to lower dose radiotherapy. This study will investigate the use of dose painting radiotherapy.
- Trial name
- BIOPROP20 (NCT02125175)
- Testing
- Hypofractionated IMRT boost Radiotherapy
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- The Clatterbridge Cancer Centre NHS Foundation Trust
Physical Activity
Formative Evaluation of The HERizon Project
This mixed methods study was the feasibility phase of a broader intervention of research (The HERizon Project) that aims to develop a theory-based physical activity intervention targeting adolescent girls in the UK and Ireland.
- Trial name
- NCT04662775
- Testing
- HERizon Project
- Where
- 3 sites in Ireland, United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.