Clinical trials: Experimental, completed
TMJ Disc Disorder, Ultrasound Therapy; Complications
Ultrasound-Guided Vs Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. a Randomized Clinical Trial
Ultrasound Guided Versus Non-Guided Prolotherapy for Treatment of Internal Derangement of Temporomandibular joint. Rationale for conducting the research: The most critical cause for guided prolotherapy is to specify the accurate…
- Conditions
- TMJ Disc Disorder, Ultrasound Therapy; Complications, TMJ, Prolotherapy
- Trial name
- NCT05627830
- Testing
- Prolotherapy
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Non-specific Chronic Neck Pain
Comparison Between Two Physical Therapy Treatments in Patients With Nonspecific Chronic Neck Pain
Introduction: Non-specific chronic neck pain is a very prevalent condition in the population ranging from 45% to 54%. Several conservative treatments have been shown to be effective and are currently used in clinical practice.
- Trial name
- NCT04695730
- Testing
- Active physical therapy (including both pain education and home exercises), Active physical therapy plus manual therapy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Bologna
Coronary Artery Disease
The Study to Assess AMI Treated With Balloon Angioplasty.
The main objective of this study is to assess the effectiveness and safety of the CYPHER™ (CYPHER SELECT™) (Sirolimus-eluting) stent in reducing the occurrence of a composite endpoint of target vessel failure (TVF) in subjects…
- Trial name
- TYPHOON (NCT00232830)
- Testing
- drug-eluting stent, bare-metal stent
- Where
- 2 sites in France, Germany
- Volunteers
- 715 people
- Sponsor
- Cordis US Corp.
Tobacco Use Disorder, Smoking
Pilot Study to Evaluate the Safety and Efficacy of Ariva® Silver Wintergreen in Reducing Cigarette Craving in Smokers
Study to determine the safety and effectiveness of Ariva® Silver Wintergreen lozenge on reducing craving for a cigarette in daily smokers.
- Trial name
- NCT01337830
- Testing
- Ariva® Silver Wintergreen, Silver Wintergreen
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Star Scientific, Inc
Covid-19, Critical Illness
Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19
Introduction: Survivors of acute respiratory failure develop persistent muscle weakness and deficits in cardiopulmonary endurance combining to limit physical functioning.
- Conditions
- Covid-19, Critical Illness, Post Intensive Care Unit Syndrome, Muscle Weakness
- Trial name
- OPTIMAL (NCT04412330)
- Testing
- ICU Recovery + Physical Therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Kentucky
Anxiety, Depression
Exploring the Efficacy of Treatments for Anxiety and Depression Among College Students
The goal of this randomized control group is to learn about effective treatments for college students experiencing anxiety and/or depression.
- Trial name
- NCT06013930
- Testing
- External Qigong, Mindfulness Meditation, Psychoeducation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of South Dakota
Malaria
Bioequivalence Trial of Pyronaridine Artesunate To-be-marketed Tablet to the Clinical Trial Reference Tablet
The primary objective of this study is to determine the bioequivalence of the combination of pyronaridine and artesunate (180:60mg) to-be-marketed tablet to the clinical trial reference tablet administered as a single total dose…
- Trial name
- NCT00682630
- Testing
- pyronaridine artesunate clinical trial reference tablets, pyronaridine artesunate to-be-marketed tablets
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medicines for Malaria Venture
Lymphoma, B-Cell, Lymphoma, Large-Cell, Immunoblastic
Rituxan/BEAM vs Bexxar/BEAM in Autologous Hematopoietic Stem Cell Transplant for Non-Hodgkin's Lymphoma (BMTCTN0401)
This study is designed as a Phase III, multicenter trial, comparing progression-free survival (PFS) after autologous hematopoietic stem cell transplantation using a standard Rituxan plus BEAM transplant regimen versus a regimen…
- Conditions
- Lymphoma, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Non-Hodgkin
- Trial name
- NCT00329030
- Testing
- Autologous transplantation using rituxan/BEAM, Autologous transplantation using Bexxar/BEAM
- Where
- 36 sites in United States
- Volunteers
- 224 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Menopause
Menopausal Sleep Fragmentation and Body Fat Gain
This study aims to investigate the impact of menopause-related sleep fragmentation on metabolic biomarkers of body fat gain. The investigators hypothesize that experimental sleep fragmentation will result in an adverse leptin…
- Trial name
- NCT03047330
- Testing
- Estradiol withdrawal, Fragmented sleep
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Rectal Cancer
LifeSeal™ Preliminary Study in Subjects Undergoing Low Anterior Resection
A preliminary Study in Subjects Undergoing Low Anterior Resection
- Trial name
- NCT01790230
- Testing
- LifeSeal™ Kit
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- LifeBond Ltd.
Opioid Prescribing
Testing a Provider-Level Feedback Intervention to Optimize Postoperative Prescribing
The objective of this project is to leverage the Michigan Surgical Quality Collaborative's (MSQC) existing network and surgeon performance feedback platform to improve opioid prescribing practices for surgeons within the network…
- Trial name
- NCT04776928
- Testing
- Push reports
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- University of Michigan
Hernia, Inguinal
Mesh Fixation and Closure of Peritoneum Following Laparoscopic Hernia Repair Using N-butyl Cyanoacrylate
Fixation of mesh and peritoneal closure during TAPP repair using n-butyl cyanoacrylate.
- Trial name
- NCT02457728
- Testing
- LiquiBandFix8
- Where
- Austria
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- St John of God Hospital, Vienna
Liposuction, Bruising
EFFECTS OF TRANEXAMIC ACID IN TUMESCENT SOLUTION FOR LIPOSUCTION PROCEDURES
The goal of this trial is to evaluate the effect of adding Tranexamic Acid (TXA) to the tumescent solution used in arm liposuction on postoperative outcomes.
- Conditions
- Liposuction, Bruising, Inflammation, Skin Condition
- Trial name
- ARMTXA (NCT06648265)
- Testing
- Tranexamic Acid (Topical), Tumescent solution with dilute lidocaine and epinephrine
- Where
- Colombia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Not Applicable as This is a Mass Balance/Pharmacokinetic Study Performed in Healthy Subjects, Apathy
Phase I Trial Evaluating the Pharmacokinetics of Single Ascending Oral Doses of IRL757 in Healthy Elderly Volunteers
This is a phase I trial evaluating the pharmacokinetics of single ascending oral doses of IRL757 in healthy elderly volunteers.
- Trial name
- NCT06699628
- Testing
- IRL757
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Integrative Research Laboratories AB
Hypertensive Heart Disease
The Personalized Chinese Herb Formulas Over Hypertensive Bradyarrhythmia
72 patients who have been diagnosed with hypertensive bradyarrhythmia were selected and randomly divided into research group and control group.
- Trial name
- NCT04505228
- Testing
- Safflower (Carthamus Tinctorius) IgG4 | Serum | Allergy, Atropine Sulfate
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Jun Xiao
Healthy
A Relative Bioavailability Study of 20 mg Famotidine Tablets Under Fasting Condition
The study was conducted as an open-label, balanced, randomized, two-treatment, two-period, two-sequence, single-dose, crossover, bioavailability study comparing famotidine tablets, USP 20 mg manufactured by OHM Laboratories with…
- Trial name
- NCT01079065
- Testing
- Famotidine
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Cigarette Smoking
Culturally Targeted & Individually Tailored Smoking Cessation Study: LGBT Smokers
For the approximately 4.6 million LGBT persons in the U.S., smoking rates among those living in urban areas are roughly twice that of heterosexuals.
- Trial name
- NCT01633567
- Testing
- Culturally Targeted Cessation Program, Non-Targeted Cessation Program
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Diabetes Mellitus, Type 2
Life-long Tele-monitoring of Patients With Type 2 Diabetes Mellitus in Central Greece
To evaluate whether patients with type 2 diabetes mellitus can be followed by simplified, centralized and large scale tele-monitoring of blood glucose levels and blood pressure, and whether this intervention produces health and…
- Trial name
- RHCluster2GR (NCT01498367)
- Testing
- Telemonitoring of patients with diabetes type 2
- Where
- Greece
- Volunteers
- 154 people
- Sponsor
- Regional Health Authority of Sterea & Thessaly
Healthy, Obesity
Open Label Randomized Clinical Study to Promote a Healthy Lifestyle in Medical Students
The main medical and social purpose of the project "It's trendy to be healthy!" is the promotion of healthy lifestyles and healthy eating among student youth.
- Conditions
- Healthy, Obesity, Nutrition, Healthy, Vitamin D Deficiency
- Trial name
- NCT05073029
- Testing
- nutrition program and modification of physical activity, synbiotic (Fructooligosaccharides+Lactobacillus rhamnosus GG ATCC 53103, 4.0х109 colony forming units - CFU), vitamin D3
- Where
- 2 sites in Ukraine
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bogomolets National Medical University
Chronic Lymphocytic Leukemia, Waldenstrom Macroglobulinemia
A Study of Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL
This is an open-label, multi-center Phase 1/2 study of oral LOXO-305 (pirtobrutinib) in patients with CLL/SLL and NHL who have failed or are intolerant to standard of care.
- Conditions
- Chronic Lymphocytic Leukemia, Waldenstrom Macroglobulinemia, Mantle Cell Lymphoma, Marginal Zone Lymphoma
- Trial name
- NCT03740529
- Testing
- Pirtobrutinib, Venetoclax, Rituximab
- Where
- 56 sites in United States, Australia and 8 more
- Volunteers
- 803 people
- Sponsor
- Loxo Oncology, Inc.
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