Clinical trials: Experimental
Parotid Gland Neoplasms
Diagnostic Accuracy of Fine Needle Aspiration in Parotid Tumors
Liberal use of fine needle aspiration biopsy of parotid gland masses is controversial. All information regarding this procedure has been retrospective.
- Trial name
- NCT00534612
- Testing
- aspiration biopsy
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- National Institute of Cancerología
Cocaine Use Disorder
Cocaine and Zolmitriptan
Cocaine potently inhibits the reuptake of serotonin (5-HT). Increased synaptic 5-HT resulting from this reuptake inhibition activates multiple 5-HT receptor subtypes.
- Trial name
- NCT05019430
- Testing
- Cocaine, Zolmitriptan
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- William Stoops
Esophageal, Gastrooesophageal Cancer
Chemotherapy for Patients With Gastroesophageal Cancers Who Have Progressed After One Prior Chemo Regimen
The purpose of this study is to evaluate the effectiveness of Cabazitaxel, as well as safety and side effects for patients with advanced gastroesophageal cancer
- Conditions
- Esophageal, Gastrooesophageal Cancer, Gastric Cancer
- Trial name
- NCT01365130
- Testing
- jevtana
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- howard safran
Metabolic Syndrome, Obese
Exercise, Statins, and the Metabolic Syndrome
Here we tested if statins or exercise plus statins had a greater capacity to lower metabolic syndrome risk factors in sedentary individuals with at least 2 metabolic syndrome risk factors.
- Conditions
- Metabolic Syndrome, Obese, Sedentary
- Trial name
- NCT01700530
- Testing
- Statin, Exercise only, Statins + Exercise
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Psychological Well-being, Hope Level
A Hope-Fostering Counseling Program to Promote Psychological Well-being Among Post-Abortion Primigravida Mothers: A Pilot Intervention Development and Feasibility Study
This study aims to investigate the feasibility of a hope-fostering counseling program among post-abortion primigravida mothers. The counseling program is composed of 6 counseling sessions based on individualized discussion.
- Conditions
- Psychological Well-being, Hope Level, Post-abortion, Hope Fostering Counseling Program
- Trial name
- NCT07488130
- Testing
- Hope-Fostering Counseling Program
- Where
- Jordan
- Volunteers
- 8 people
- Sponsor
- University of Jordan
Hemorrhoids
Irritation and Anal Bleeding in Patients Affected by Hemorrhoids.
Haemorrhoidal disease is an increasingly frequent benign condition, able to negatively affect the quality of working and relationship life in affected individuals.The primary objective of the study is the comparative assessment…
- Trial name
- IR-AN-BLEED (NCT03569930)
- Testing
- flavonoid-based supplements, Centella Complex, standard of care
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- University of Roma La Sapienza
Cancer, Adherence to Medication Regime
Mobile Application to Assist Adherence to Oral Anticancer Agents and Symptom Management
The use of oral anticancer agents (OAAs) in cancer treatment has increased especially in the last two decades. The use of mobile health technologies in the management of OAA can be beneficial in terms of treatment adherence and…
- Conditions
- Cancer, Adherence to Medication Regime, Symptom Management
- Trial name
- NCT04626830
- Testing
- Mobile Application Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Baskent University
Cognitive Dysfunction, Covid19
Improving Cognitive Health in COVID-19 Survivors
The primary objective of this study is to investigate the efficacy of AKL-T01, a remotely-delivered digital cognitive intervention, relative to a waitlist control in improving cognitive functioning in COVID-19 survivors.
- Trial name
- NCT04843930
- Testing
- AKL-T01
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Weill Medical College of Cornell University
Thyroid Nodule
Percutaneous Ethanol Injection for Benign Cystic Thyroid Nodules
Use of ethanol injection in treatment of cystic thyroid nodule
- Trial name
- NCT03257930
- Testing
- ethanol injection
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- hassan harby mohamed
Pleasure
RS-fMRI to Nutrient Shakes
Resting state functional magnetic resonance imaging (rsfMRl) of the brain is used to measure pleasantness after consumption of four different milkshakes with added sugars or sweeteners.
- Trial name
- NCT02745730
- Testing
- Glucose, Fructose, Sucralose
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Multiple Sclerosis
Blood Flow Restriction for Upper Limb Rehabilitation in People With Multiple Sclerosis. A Randomized Controlled Trial (BFRT-EM)
Although the Blood Flow Restriction Training (BFRT) system has attracted the attention of health professionals, research on this tool in people with neurological pathology, particularly multiple sclerosis (MS), is very limited.
- Trial name
- BFRT-EM (NCT06795230)
- Testing
- Muscle strengthening (BFRT), Conventional physical therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Rey Juan Carlos
Postoperative Delirium, Postoperative Cognitive Dysfunction
fMRI Connectivity in Fracture Hip Patients
The long-term goal of this study is to evaluate cognitive function preoperatively and develop techniques of intervention in the perioperative period which would optimize brain function and functional recovery following surgery.
- Trial name
- NCT02997930
- Testing
- fMRI, Montreal Cognitive Assessment (MoCA), Digital Clock Drawing Test Command and Copy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Cardiomyopathy
A Phase I Trial on the Relative Bioavailability and Food Effect of HRS-1893 Tablets in Healthy Subjects
This Phase I clinical trial will investigate the relative bioavailability between two formulations of HRS-1893 tablets and the influence of food on the drug's pharmacokinetics in healthy adult participants.
- Trial name
- NCT07272330
- Testing
- HRS-1893 tablet A, HRS-1893 tablet B
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Temporomandibular Disorder
Photobiomodulation In the Masseter and Temporal In Patients With Temporomandibular Joint Dysfunction
Background: According to the International Association for the Study of Pain (IASP), the term temporomandibular disorder (TMD) regards a subgroup of orofacial pain, the symptoms of which include pain or discomfort in the…
- Trial name
- NCT03005730
- Testing
- phototherapy
- Volunteers
- 15 people
- Sponsor
- University of Nove de Julho
Local Anesthesia in Dentistry
Effect of the CALAJECT System on Pain Perception, Heart Rate, and Blood Pressure During Inferior Alveolar Nerve Block: A Randomized Controlled Clinical Trial
This randomized controlled clinical trial aims to compare the effects of a computer-controlled local anesthetic delivery system (CALAJECT) and the conventional injection technique for inferior alveolar nerve block (IANB) on…
- Trial name
- NCT07901530
- Testing
- Computer-Controlled Local Anesthetic Delivery System (CALAJECT), Conventional Inferior Alveolar Nerve Block Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 286 people
- Sponsor
- Inonu University
TMJ Disc Disorder, Ultrasound Therapy; Complications
Ultrasound-Guided Vs Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint. a Randomized Clinical Trial
Ultrasound Guided Versus Non-Guided Prolotherapy for Treatment of Internal Derangement of Temporomandibular joint. Rationale for conducting the research: The most critical cause for guided prolotherapy is to specify the accurate…
- Conditions
- TMJ Disc Disorder, Ultrasound Therapy; Complications, TMJ, Prolotherapy
- Trial name
- NCT05627830
- Testing
- Prolotherapy
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Non-specific Chronic Neck Pain
Comparison Between Two Physical Therapy Treatments in Patients With Nonspecific Chronic Neck Pain
Introduction: Non-specific chronic neck pain is a very prevalent condition in the population ranging from 45% to 54%. Several conservative treatments have been shown to be effective and are currently used in clinical practice.
- Trial name
- NCT04695730
- Testing
- Active physical therapy (including both pain education and home exercises), Active physical therapy plus manual therapy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Bologna
Coronary Artery Disease
The Study to Assess AMI Treated With Balloon Angioplasty.
The main objective of this study is to assess the effectiveness and safety of the CYPHER™ (CYPHER SELECT™) (Sirolimus-eluting) stent in reducing the occurrence of a composite endpoint of target vessel failure (TVF) in subjects…
- Trial name
- TYPHOON (NCT00232830)
- Testing
- drug-eluting stent, bare-metal stent
- Where
- 2 sites in France, Germany
- Volunteers
- 715 people
- Sponsor
- Cordis US Corp.
Melasma
Secretome TGF Beta 3
A therapeutic modality currently being developed for melasma is secretome. Secretome is a bioactive molecule secreted by mesenchymal stem cells in a conditioned medium containing a large number of growth factors, cytokines…
- Trial name
- TGF Beta 3 (NCT07137130)
- Testing
- Concentrated secretome Injection 3 mL, Concentrated secretome Injection 3 mL with addition of TGF Beta 3
- Where
- Indonesia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Tobacco Use Disorder, Smoking
Pilot Study to Evaluate the Safety and Efficacy of Ariva® Silver Wintergreen in Reducing Cigarette Craving in Smokers
Study to determine the safety and effectiveness of Ariva® Silver Wintergreen lozenge on reducing craving for a cigarette in daily smokers.
- Trial name
- NCT01337830
- Testing
- Ariva® Silver Wintergreen, Silver Wintergreen
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Star Scientific, Inc
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