Clinical trials: Experimental, completed
Influenza, Virus Diseases
Safety of and Immune Response to a Bird Flu Virus Vaccine (H9N2) in Healthy Adults (Study B)
Avian influenza (AI), also known as bird flu, has become a major public health concern in many regions of the world. The purpose of this study is to evaluate the safety of and immune response to an AI vaccine in healthy adults.
- Trial name
- NCT00380237
- Testing
- H9N2 (6-2) AA ca Reassortant (A/Chicken/Hong Kong/G9/97 x A/Ann Arbor/6/60 ca)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Weight Loss, Obesity
Using Social Incentives and Gamification for Weight Loss Promotion
This is a 36-week, three-arm randomized, controlled trial using a team-based model to compare two weight loss programs to control.
- Conditions
- Weight Loss, Obesity, Physical Activity
- Trial name
- NCT02564445
- Testing
- Gamification, Share Data with PCP, Feedback on weight
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Eating Disorders, Maladaptive Personality Trait
MICBT for Non-underweight Adults With Eating Disorders
Eating disorders (ED) are severe but treatable conditions, but there are large margin for improvements in terms of efficacy and adherence.
- Conditions
- Eating Disorders, Maladaptive Personality Trait, Emotion Regulation, Personality
- Trial name
- MICBT-ED (NCT05503745)
- Testing
- CBT-F+MIT, CBT-E
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Centro Trattamento Integrato: Disturbi Alimentari e Obesita
Lung Cancer
Study of GRN163L With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Non Small Cell Lung Cancer
The purpose of this study is to determine the safety and the maximum tolerated dose (MTD) of GRN163L when administered in combination with a standard paclitaxel/carboplatin regimen to patients with advanced or metastatic…
- Trial name
- NCT00510445
- Testing
- Imetelstat Sodium (GRN163L)
- Where
- 4 sites in United States
- Volunteers
- 27 people
- Sponsor
- Geron Corporation
Neurotoxicity, Pain
Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
RATIONALE: Lamotrigine may be effective in reducing pain, numbness, tingling, and other symptoms of peripheral neuropathy. It is not yet known whether lamotrigine is effective in treating peripheral neuropathy caused by…
- Conditions
- Neurotoxicity, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00068445
- Testing
- lamotrigine
- Where
- 23 sites in United States
- Volunteers
- 131 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Hepatitis C, Chronic
A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Ribavirin in Hemophiliac Patients With Chronic Hepatitis C.
This study will evaluate the efficacy and safety of PEGASYS plus ribavirin in male patients with hemophilia A and chronic hepatitis C. All patients will receive PEGASYS 180 micrograms s.c. weekly plus ribavirin 1000-1200mg p.o.
- Trial name
- NCT00475072
- Testing
- peginterferon alfa-2a [Pegasys], ribavirin
- Where
- Mexico
- Volunteers
- 14 people
- Sponsor
- Hoffmann-La Roche
Photodamaged Skin
Comparison of the Effect of Vaseline and Bepanthen® "Wund- Und Heilsalbe" on the Wound Healing Following Laser Therapy
In the field of dermatology the healing process and therefore the success of a laser treatment are strongly determined by an appropriate postoperative treatment of the laser-treated skin.
- Trial name
- CO2 (NCT03095872)
- Testing
- CO2-laser, Vaseline, Bepanthen
- Where
- Germany
- Volunteers
- 37 people
- Sponsor
- RWTH Aachen University
Healthy Subjects
Effect of Prayer on Conditioned Pain Modulation and on Pain Intensity in Healthy Religious University Students
With this study the investigators wish to examine the effect of prayer on pain intensity and on the conditioned pain modulation in healthy religious university students.
- Trial name
- NCT04614272
- Testing
- Prayer, Reading a poem
- Where
- Lebanon
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Antonine University
Inflammatory Lung Injury, Ischemia-Reperfusion Lung Injury
Anesthetics to Prevent Lung Injury in Cardiac Surgery
The purpose of this study is to investigate whether the use of inhaled anesthetics, compared to intravenous anesthetics, can affect the amount of lung inflammation and postoperative respiratory complications seen after cardiac…
- Conditions
- Inflammatory Lung Injury, Ischemia-Reperfusion Lung Injury, Postoperative Pulmonary Complications
- Trial name
- APLICS (NCT02918877)
- Testing
- Sevoflurane, Propofol
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Beth Israel Deaconess Medical Center
Healthy Volunteers
A Study of TAK-881 in Healthy Adults
The main aims of this study are to check for side effects from TAK-881 in healthy adults and to learn how much TAK-881 they can receive without getting side effects from it.
- Trial name
- NCT05059977
- Testing
- TAK-881
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Takeda
Crohn´s Disease
Trichuris Suis Ova (TSO) Suspension Versus Placebo in Active Crohn's Disease
This study will run in centers in Germany, Denmark, Austria, Czech Republic, and Switzerland, only. This proof-of-concept study aims to evaluate the efficacy of three doses of oral TSO suspension vs.
- Trial name
- TRUST-2 (NCT01279577)
- Testing
- Low dose TSO, Medium dose TSO, High dose TSO
- Where
- Germany
- Volunteers
- 254 people
- Sponsor
- Dr. Falk Pharma GmbH
Implantable Cardioverter Defibrillator (ICD), Aromatherapy
Implantable Cardioverter Defibrillator (ICD) Patients and Inhalation Aromatherapy
The effective management of anxiety and fatigue, which lead to negative physical, social, and psychological impacts and increase treatment costs in individuals with implanted cardioverter-defibrillators (ICD), is of great…
- Conditions
- Implantable Cardioverter Defibrillator (ICD), Aromatherapy, Anxiety, Fatigue Symptom
- Trial name
- ICD (NCT06874777)
- Testing
- Aromatherapy group
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- TC Erciyes University
Migraine
A Study of LY2951742 (Galcanezumab) in Japanese Participants With Episodic Migraine
The main purpose of this study is to determine the efficacy of the study drug Galcanezumab in Japanese participants with episodic migraine.
- Trial name
- NCT02959177
- Testing
- Galcanezumab
- Where
- 47 sites in Japan
- Volunteers
- 459 people
- Sponsor
- Eli Lilly and Company
Motor Activity, Parent-Child Relations
Parent PLAYSHOP: A Physical Literacy Training Workshop for Parents
The objective of this research is to 1) determine the impact of a physical literacy training workshop for parents of preschool children (3-5 years) on their knowledge and confidence levels in regards to engaging in meaningful…
- Trial name
- NCT04394312
- Testing
- Parent PLAYSHOP
- Where
- 2 sites in Canada
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Pregnancy Loss, Frozen Embryo Transfer
Substituted Frozen Embryo Transfer Cycles With GnRH-agonist Supplementation
The aim of this study is to compare two FET protocols by modifying the substituted FET cycle in order to maintain a higher ongoing positive pregnancy rate and thus reduce the early pregnancy loss.
- Trial name
- NCT01943812
- Testing
- Estradiol and progeterone
- Where
- 2 sites in Denmark
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Enuresis, Nocturnal
The Effect of Selecting Treatment With Desmopressin or Alarm to Children With Enuresis Based on Home Recordings.
The aim of this study is to investigate the importance of clinical characterization of children with monosymptomatic nocturnal enuresis (MNE) in order to improve treatment efficacy.
- Trial name
- DRYCHILD (NCT03389412)
- Testing
- Desmopressin, Conditional alarm
- Where
- 6 sites in Belgium, China and 2 more
- Volunteers
- 324 people
- Sponsor
- University of Aarhus
Anemia, Renal Failure
Heme Iron Polypeptide for Iron Deficiency Anemia in Chronic Renal Failure
The purpose of this study is to determine if oral Heme Iron Polypeptide is as effective as intravenous (IV) iron sucrose in the treatment of iron-deficiency anemia for patients with chronic kidney disease.
- Trial name
- NCT00318812
- Testing
- Heme Iron Polypeptide (Proferrin), Iron sucrose (Venofer)
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Ottawa Hospital Research Institute
Healthy Nutrition, Culinary Medicine
Increasing Vegetable Intake Using Monosodium Glutamate: A Reduced-Effort Intervention
Food Intake Study: This will be a 4-week randomized controlled intervention study with a vegetable intake questionnaire, daily food intake, and seasoning usage measurement to test the acceptability of different seasoning…
- Conditions
- Healthy Nutrition, Culinary Medicine, Sodium Excess
- Trial name
- NCT05591612
- Testing
- Salt replacement seasoning (50% salt and 50% MSG) mix, Salt replacement seasoning (70% salt and 30% MSG) mix, NaCl (sodium chloride/table salt)
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Alzheimer's Disease
Repeated Subcutaneous Administration of ABvac40 in Mild to Moderate Alzheimer's Disease Patients
This first time study in humans was designed to assess tolerability and safety of repeated subcutaneous injections of ABvac40, an active immunization against the C-terminal end of Abeta1-40.
- Trial name
- NCT03113812
- Testing
- ABvac40
- Volunteers
- 24 people
- Sponsor
- Araclon Biotech S.L.
Spinal Cord Injuries, Neurogenic Bladder
Intravesical Lactobacillus to Reduce Urinary Symptoms After Spinal Cord Injury
The objectives of the proposed research among this population are: 1) to define clinically meaningful change (i.e. differentiating states of health and illness) with respect to urinary symptoms, urine inflammation, cultivable…
- Trial name
- NCT04373512
- Testing
- Culturelle 10 Billion CFU Capsule (2 doses), Culturelle 10 Billion CFU Capsule (4 doses)
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Medstar Health Research Institute
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