Clinical trials: Experimental
Healthy
Using Artificial Intelligence to Improve Radiologists' Performance in Radiology Report Writing: a Randomised Controlled Trial
This is a randomised controlled trial to assess whether artificial intelligence software can improve radiologists' performance in radiology report writing and improve the quality of radiology reports.
- Trial name
- NCT06907927
- Testing
- Control group, Experimental group
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Diabetes
Empowerment-based Complementary and Alternative Medicine (ECAM)
This phase study will use a randomized trial method to evaluate the performance of the ECAM educational app in the promotion of CAM health literacy and communication among patients with diabetes.
- Trial name
- CAM (NCT06317584)
- Testing
- Experimental: Empowerment Application for CAM Health Education, Written Paper for CAM Health Education
- Where
- Taiwan
- Volunteers
- 88 people
- Sponsor
- Chang Gung University of Science and Technology
Physical Activity, Quality of Life
A Novel Mat Exercise Program Improves Functional Fitness, Activity Levels, and Quality of Life in Older Adults
In this study, investigators recruited older adults aged 60 to 80 years and utilized a parallel experimental design. A total of 32 participants were randomly assigned to either the experimental or control group.
- Conditions
- Physical Activity, Quality of Life, Functional Fitness
- Trial name
- NCT06898528
- Testing
- The group-based mat exercise training on experimental group., The control group
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Tooth Bleaching, Pain
Effect of Andiroba on Control of Post-whitening Tooth Sensitivity
This randomized clinical trial will evaluate the effect of an experimental gel containing andiroba oil (Carapa guianensis) in reducing postoperative tooth sensitivity caused by bleaching with 35% hydrogen peroxide.
- Conditions
- Tooth Bleaching, Pain, Dentin Desensitizing Agents
- Trial name
- NCT06614764
- Testing
- AG (experimental Andiroba Gel), KF2G (Potassium nitrate gel)
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Universidade Federal do Para
Low Back Pain
Effect of Pilates Core Stabilization in Adjunct With Plyometric Shoulder Training on Low Back Pain in Fast Bowlers(RCT)
This RCT will seek to determine both the Pilates core stabilization and plyometric shoulder training on LBP in fast bowlers. The research problem will emphasize the absence of detailed rehabilitation protocols that address the…
- Trial name
- NCT06901804
- Testing
- Experimental Group (training and stabilization), Control Group (physiotherapy and exercise)
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Superior University
Heart Failure with Mid-range Ejection Fraction, Heart Failure with Preserved Ejection Fraction
Spironolactone in the Treatment of Heart Failure
The purpose of this study is to determine whether the treatment of patients with HFmrEF and HFpEF at high risk of cardiovascular events with the mineralocorticoid receptor antagonist (MRA) spironolactone reduces a composite of…
- Trial name
- SPIRIT-HF (NCT04727073)
- Testing
- Experimental: Spironolactone
- Where
- 69 sites in Austria, France and 3 more
- Volunteers
- 743 people
- Sponsor
- Charite University, Berlin, Germany
Congenital Zika Syndrome
Impacts of a Physical Therapy Protocol on Motor Function in Children With Congenital Zika Syndrome
The study aims to evaluate the effects of a specialized physiotherapy protocol aimed at the motor function of children with Congenital Zika Virus Syndrome.
- Trial name
- NCT06900322
- Testing
- Experimental Group (stimuli and handling; physical therapy [PediaSuit]), control group (conventional physical therapy)
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- Gabriela Lopes Gama
Basketball Players
Plyometry and Tapping in the Functional Improvement of Non-professional Basketball Players
Introduction. In basketball, the lower extremities have the highest prevalence of injury, regardless of gender and professional category. Objective.
- Trial name
- NCT06367790
- Testing
- Experimental group, Control group
- Where
- Spain
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Nearsightedness
Effect of Defocus in Soft Contact Lenses on Internal Retinal Vascularization
The purpose of this study is to gain a better understanding of the retinal vascular changes that occur in response to the optical effect of a myopic defocus daily disposable soft contact lens (MDSL) in a group of healthy young…
- Trial name
- NCT06527274
- Testing
- Experimental: Myopic defocus soft lens design (MDSL), Active Comparator: Single vision soft lens design (SVSL
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
MYOPIA
Myopia Adjustment Using Dual-intervention: Red-Light Therapy & Innovative Design in Orthokeratology
This clinical trial investigates the efficacy of combining orthokeratology (OK) lenses with repeated low-level red-light (R.L.R.L.) therapy in slowing the progression of myopia in children classified as ortho-k non-responders.
- Trial name
- MADRID (NCT06899139)
- Testing
- Orthokeratology Lens Wear, Repeated Low-Level Red-Light Therapy Intervention Type: Device Description: Participants in the experimental group will receive repeated low-level red-light (R.L.R.L.) therapy twice daily using a no
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Centro de Miopía Fernández-Velázquez
Toe Flexor Strength
Improving Foot Strength in Vocational Ballet Dancers
Professional dancers subject their feet to high forces through frequent jumping, repeated heel rises, insufficient shoe cushioning, and a high degree of foot mobility.
- Trial name
- NCT06589050
- Testing
- "Toe flexor device" experimental group, "Inclined Heel Rise" experimental group
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Bern
Sports Physical Therapy
Upper Limb Blood Flow Restriction in Handball Players
Introduction. Blood flow restriction therapy involves the use of an occlusion cuff placed over an extremity resulting in a partial reduction of arterial blood flow and total restriction of venous return. Objectives.
- Trial name
- NCT06423196
- Testing
- Experimental group
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Multiple Sclerosis
Rehabilitative Protocols in Progressive Multiple Sclerosis Treated with Anti CD20 Monoclonal Antibodies
Progressive multiple sclerosis (MS) patients have usually a worsening clinical course and it remains unclear if rehabilitation can indeed slow down the progression of the disease.
- Trial name
- Reup (NCT06894940)
- Testing
- Active Comparator #1, Experimental
- Where
- Italy
- Volunteers
- 82 people
- Sponsor
- University of Pavia
Overweight and Obesity, Pre-diabetes
SWITCH Diets Study: Self-monitoring With Internet Technology to Choose Healthy Diets
The goal of the Self-monitoring With Internet Technology to Choose Healthy Diets (SWITCH) study is to examine a 12-week remotely delivered program designed to help adults adopt a healthy dietary lifestyle and lose weight in a…
- Trial name
- SWITCH (NCT06245369)
- Testing
- learning modules (within app), SWITCH app (self-regulation features) - Experimental, SWITCH app (self-regulation features) - Comparator
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Cerebral Infarction Recovery, Rehabilitation Treatment
The Application of Kinesio Taping Technique in the Early Upper Limb Functional Activities Induction of Hemiplegic Patients After Stroke
1. To observe the inducing and promoting effect of kinesio taping technique on the recovery of upper limb function in early-stage stroke patients. 2.
- Conditions
- Cerebral Infarction Recovery, Rehabilitation Treatment, Upper Extremity Motor Function, Emg Biofeedback
- Trial name
- NCT06834750
- Testing
- Experimental Group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Lumbar Radiculopathy
Effects of Adding Balneotherapy to a Physical Therapy Program in Patients With Chronic Lumbar Radiculopathy
The aim of this study is to investigate the effects of adding balneotherapy to the conventional physical therapy program on neuropathic pain, disability, daily living activities, and sleep quality in patients with chronic lumbar…
- Trial name
- NCT06846970
- Testing
- Experimental, Active Comparator
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Afyonkarahisar Health Sciences University
Vertigo, BPPV
Treating the Symptoms of Vertigo in a Real-world Setting Using the OtoBand
The goal of this virtual clinical trial is to determine the effectiveness of two study devices in providing temporary relief to adults aged 18-70 who suffer from symptoms of chronic vestibular vertigo.
- Conditions
- Vertigo, BPPV, Meniere Disease, Labrynthitis
- Trial name
- NCT05960786
- Testing
- Otoband Experimental
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Otolith Labs
Diabetic Foot Ulcer
The Effect of Breathing Exercise and Pressurized Cold Application on Pain and Anxiety During Sharp Debridement
In our planned study, it is envisaged that patients who receive breathing exercises and pressurized cold application will experience a decrease in the level of pain they feel during the debridement process, a decrease in their…
- Trial name
- NCT06886633
- Testing
- Breathing exercise, Experimental: Pressurized Cold Application Group
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Harran University
Balance Impairments in Stroke Patients
Can Lumbar Mulligan Mobilization Improve Gait, Balance, and Trunk Position Sense After Stroke?
Stroke is a pathology caused by disturbances in the brain's arterial circulation, leading to high morbidity rates. Individuals who experience a stroke often face neurological impairments such as motor, sensory, and cognitive…
- Trial name
- NCT06887114
- Testing
- Experimental Group (Mulligan Mobilization + Conventional Therapy), (Conventional Therapy Only)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gulhane School of Medicine
Nursing Students, Intramuscular Injection
Effect of Microteaching on Ventrogluteal Injection Training
Nursing education plays a crucial role in ensuring nurses possess the necessary knowledge and skills to provide high-quality care.
- Trial name
- NCT06884124
- Testing
- Experimental, Control
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ataturk University