Clinical trials: Experimental
Breathing Exercises, Coronary Angiography
The Effect of Breathing Exercise on Anxiety, Pain and Life Findings in Patients Undergoing Coronary Angiography
This randomised controlled trial will be conducted to evaluate the effect of breathing exercise on anxiety, pain and vital signs in patients undergoing coronary angiography before angiography.
- Trial name
- NCT06602128
- Testing
- Experimental: Breathing Exercise Application Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kahramanmaraş İstiklal University
Breathing Exercises, Critical Care Nursing
The Effect of Breathing Exercise Applied to Intensive Care Nurses on Fatigue and Perceived Stress
The aim of this randomized controlled trial was to investigate the effect of breathing exercise on fatigue and stress in intensive care nurses.
- Trial name
- NCT06642376
- Testing
- Experimental: Breathing Exercise Application Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaraş İstiklal University
Advanced Soft Tissue Sarcoma
Randomized Trial in Advanced, Metastatic or Unresectable Soft Tissue Sarcoma After Failure of Standard Treatments.
Phase II study in patient with advanced Soft Tissue Sarcoma (STS) patients who have already received or are not suitable, for a doxorubicin-based treatment.
- Trial name
- TOMAS2 (NCT03838744)
- Testing
- Standard arm: Trabectedin in monotherapy, Experimental arm: Trabectedin + Olaparib
- Where
- 13 sites in Italy
- Volunteers
- 130 people
- Sponsor
- Italian Sarcoma Group
Neck Pain, Whiplash Injuries
Implementation and Evaluation of Neck-specific Exercises
Persistent pain and disability in whiplash-associated disorders (WAD) grade II and III are common. Randomized controlled studies (RCTs) have shown promising result for neck-specific exercise (NSE) programmes in chronic WAD with…
- Conditions
- Neck Pain, Whiplash Injuries, Neck Disorder
- Trial name
- NCT05198258
- Testing
- Implementation strategy - experimental group, Implementation - control group
- Where
- 7 sites in Sweden
- Volunteers
- 20 people
- Sponsor
- Sormland County Council, Sweden
Acute Ischemic Stroke
Efficacy and Safety of Human Urinary Kallidinogenase Combined With Endovascular Therapy in Acute Ischemic Stroke With Large Vessel Occlusion
The purpose of this study is to evaluate the safety and efficacy of Human Urinary Kallidinogenase combined with endovascular therapy in acute ischemic stroke (AIS) patients with large vessel occlusion.
- Trial name
- HEAL (NCT06211712)
- Testing
- Experimental: Human Urinary Kallidinogenase
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Huashan Hospital
Diabetes type2
Benefits of Nutritional Ingredients for Type 2 Diabetes
This is a prospective randomized, double-blinded, parallel design study to evaluate the benefits of long-term consumption of two experimental blends of liquid supplements.
- Trial name
- NCT06327711
- Testing
- Control: CHO Blend, Experimental: CHO Blend plus AN100
- Where
- United States
- Sponsor
- Abbott Nutrition
Neuropsychological Rehabilitation Program (VIRTRAEL/LUCCIDY), Standard Training (TAU)
The Role of Executive Functioning in Complex Post-Traumatic Stress Disorder Among Female Survivors of Intimate Partner Violence
This project aims to investigate neuropsychological alterations in women with PTSD (Post-Traumatic Stress Disorder) and complex PTSD (CPTSD), survivors of intimate partner violence (IPV), and to implement a cognitive stimulation…
- Trial name
- BELIEVE-CPTSD (NCT06706882)
- Testing
- Experimental Training: VIRTRAEL/LUCCIDY, Active Comparator: Standard Training: Reflection Group (TAU) (Andalusian Institute of Women, 2010)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Chronic Pain
Safety and Efficacy of Medical Cannabis Oil in the Treatment of Patients with Chronic Pain
Seeking for effective therapeutic strategies, the investigators are proposing to test the effectiveness of different formulations of medical cannabis oil to alleviate chronic pain, which was partially relieved with conventional…
- Trial name
- NCT03337503
- Testing
- THC and CDB in a 1 to 1 ratio, Experimental: THC and CBD in a 1 to 2 ratio, High CBD with trace THC oil
- Where
- Canada
- Volunteers
- 161 people
- Sponsor
- Santé Cannabis
Xerostomia, Dry Mouth
Efficacy of Transcutaneous Electrical Nerve Stimulation in Patients With Xerostomia (ETENX)
Saliva is a complex fluid with essential functions in the oral cavity, such as lubricating tissues, protecting against microorganisms, and facilitating processes like chewing, swallowing, and speaking.
- Trial name
- ETENX (NCT06708195)
- Testing
- Group experimental
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad de Murcia
Anxiety and Depression, Psychiatric Inpatients
Psychological Treatment in Psychiatric Inpatient Care.
There is a lack of psychological treatments within inpatient psychiatric care while there is support for active psychological interventions having an effect on psychiatric problems.
- Trial name
- NCT06702254
- Testing
- Experimental: Psychological manualized treatment with CBT and ACT, Treatment as usual
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Stockholm
Depressive Symptoms
Social Worker-led Mindfulness-based Intervention for Older People
Preliminary findings from a previous study conducted by the investigators suggest that a task-shared approach with modified mindfulness-based cognitive therapy (MBCT) supported by social workers is beneficial in managing…
- Trial name
- NCT06528132
- Testing
- Mindfulness-based intervention (MBI) (enhanced with peer supporters), Experimental: social worker-led MBI (without peer supporters)
- Where
- 13 sites in Hong Kong
- Volunteers
- 207 people
- Sponsor
- The University of Hong Kong
Neuromyelitis Optica Spectrum Disorders
A Study to Evaluate the Efficacy and Safety of JYP0061 in Patients With Acute Neuromyelitis Spectrum Disease (NMOSD)
The goal of this clinical trial is to evaluate the efficacy and safety, of JYP0061 in acute NMOSD patients. The main questions it aims to answer are: efficacy and safety of JYP0061 in acute NMOSD patients.
- Trial name
- NCT06697535
- Testing
- JYP0061, Intravenous Glucocorticoids, Oral Glucocorticoids
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Guangzhou JOYO Pharma Co., Ltd
Sports Physical Therapy
Effects of Rhythmic Stabilization With and Without Closed Kinetic Chain Exercises Among Fast Bowlers
Effects of Rhythmic stabilization with and without Closed Kinetic Chain Exercises on upper body strength, endurance and balance among fast bowlers
- Trial name
- NCT06697873
- Testing
- Experimental Group: A, Experimental: Group B
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Healthy Subjects
Study of TAVO101 in Healthy Volunteers
This is a Phase 1, single ascending dose study designed to investigate TAVO101, administered as an IV infusion in healthy subjects.
- Trial name
- NCT05298046
- Testing
- Experimental: TAVO101
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Tavotek Biotherapeutics
Soccer Performance
Effects of Coordinative Warm-Up Exercise Protocols on the Technical and Cognitive Performance of Soccer Players
The aim of this study is to evaluate the effects of 12 weeks of warm-up protocols administered to elite soccer players on technical-coordination performance and levels of cortisol, adrenaline, noradrenaline, and dopamine…
- Trial name
- NCT06690853
- Testing
- Experimental Coordinative training, Traditional training (control group)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Molise
Advanced Solid Tumors
A Clinical Trial Evaluating JYP0035 Capsule Monotherapy in Patients With Advanced Solid Tumors
The goal of this Phase I clinical trial is to evaluate the safety, tolerability, and pharmacokinetic characteristics of the JYP0035 capsule in patients with advanced solid tumors.
- Trial name
- NCT06158477
- Testing
- JYP0035 Experimental Drug Treatment
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Chengdu JOYO pharma Co., Ltd.
Healthy, Adolescent Development
Discovering Adolescents' Talents and Life Projects as a Key Factor in Their Life Satisfaction
Recent data show a deterioration in the mental health of adolescents, with an increase in anxiety, depression, sleep disturbances, eating disorders, and a significant increase in suicides.
- Trial name
- GENIALADOLES (NCT06473155)
- Testing
- Experimental: Humanistic Integrative Psychotherapy and Identity Exploration (HIP+EYME), Experimental: Humanistic Integrative Psychotherapy, Identity, and Geniotype Exploration (HIP+EYME+GENIOTYPE)
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre Besai
Prostate Biopsy
Evaluation of the Effect on Pain of Attentional Diversion Associated with Hypnotic Induction by Virtual Reality (VRH) in Perioperative Prostate Biopsies Under Local Anesthesia:
The primary objective of the study is to prospectively compare perioperative pain assessed in patients undergoing targeted prostate biopsies, either transrectally or transperineally, under local anesthesia with or without a…
- Trial name
- HYPNOSURG-VR (NCT06691438)
- Testing
- prostate biopsy
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea
OROPHARYNGEAL MYOFUNCTIONAL THERAPY IN OBSTRUCTIVE SLEEP APNEA
Obstructive Sleep Apnea (OSA) is a prevalent nocturnal breathing disorder among the general population. Oropharyngeal myofunctional therapy (OMT) is an alternative conservative treatment used to improve OSA, associated health…
- Trial name
- NCT06681974
- Testing
- CONTROL:Information form with hygienic-dietary measures or sleep hygiene guidelines is provided and explained., EXPERIMENTAL: program of exercises that will be composed of 4 blocks
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Instituto de Investigación Marqués de Valdecilla
Subacromial Impingement Syndrome
Comparison of Scapular Stabilization and Mobilizations in Sub Acromial Pain Syndrome
The aim of this research is to compare the effect Comparison of scapular stabilization exercises and scapular mobilizations on shoulder pain, scapular kinematics, disability and functional limitations in patients with sub…
- Trial name
- NCT06426888
- Testing
- Experimental interventional group 1(scapular stabilization exercise therapy), Experimental :interventional group II (scapular mobilizations)
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University