Clinical trials: Experimental, completed
Hypertension
Clinical Trial to Evaluate the Bioavailability and Safety of AGSAV301
The purpose of this study is to evaluate the bioavailability and safety of AGSAV301 tablet in healthy male volunteers.
- Trial name
- NCT01536353
- Testing
- AGSAV301, Exforge 10/160
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
Hypoactive Sexual Desire Disorder
Safety and Efficacy of LibiGel® for the Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women
This study is a randomized, double-blind, placebo-controlled, multi-center study of the safety and efficacy of LibiGel® 300mcg in the treatment of HSDD in surgically menopausal women
- Trial name
- BLOOM (NCT00613002)
- Testing
- testosterone gel
- Where
- 63 sites in United States, Canada
- Volunteers
- 597 people
- Sponsor
- BioSante Pharmaceuticals
Knowledge, Attitudes, Practice
The Effect of Pain Education on Multidisciplinary Healthcare Students' Understanding of Chronic Pain
Chronic pain is the leading cause of disability worldwide affecting just under 28 million people in the UK. Chronic pain conditions require a biopsychosocial rather than a biomedical model of care.
- Trial name
- NCT03710837
- Testing
- Pain neuroscience education, Red flag education
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Teesside University
Cancer
Patient Empowerment and Risk-assessed Treatment to Improve Outcome in the Elderly After Onco-surgery
The aims of this study are to investigate whether patient empowerment, including information and decision-aids adapted to the risk and the need of the elderly patient, can improve outcome in an evidence-based modular pathway in…
- Trial name
- PERATECS (NCT01278537)
- Testing
- Information
- Where
- 3 sites in Germany
- Volunteers
- 690 people
- Sponsor
- Charite University, Berlin, Germany
Pulmonary Arterial Hypertension
FK506 (Tacrolimus) in Pulmonary Arterial Hypertension
Mutations in bone morphogenetic protein receptor 2 (BMPR2) are present in >80% of familial and ~20% of sporadic pulmonary arterial hypertension (PAH) patients.
- Trial name
- TransformPAH (NCT01647945)
- Testing
- FK506 level < 2 ng/ml, FK506 level 2-3 ng/ml, FK506 level 3-5 ng/ml
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Edda Spiekerkoetter
Prostate Cancer
Exercise Intervention Among Men With Prostate Cancer Initiating Androgen Deprivation Therapy
This research study is evaluating the impact and feasibility of a 12-week brisk walking and moderate strength training exercise intervention including a virtual component in men who are initiating androgen deprivation therapy…
- Trial name
- NCT03070145
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Dana-Farber Cancer Institute
Bacteraemia Caused by Gram-Negative Bacteria
Antibiotic Durations for Gram-negative Bacteremia
Gram-negative bacteremia (GNB) is a frequent hospital \& community-acquired infection, yet there is as yet no evidence from randomized studies on the optimal duration of antibiotic therapy.
- Trial name
- PIRATE (NCT03101072)
- Testing
- "Fixed long" antibiotic course of 14 days, "Fixed short" antibiotic course of 7 days, "Individualized duration" of antibiotic therapy
- Where
- 3 sites in Switzerland
- Volunteers
- 504 people
- Sponsor
- University of Geneva, Switzerland
Type 2 Diabetes, Coronary Heart Disease
Trial on Safety & Performance of TAXUS Element vs. XIENCE Prime Stent in Treatment of Coronary Lesion in Diabetics
The TUXEDO-India is a prospective, single blind, multi-center randomized clinical trial to assess the TAXUS Element™ in a consecutive population of diabetic patients with coronary artery disease undergoing coronary…
- Trial name
- Tuxedo (NCT03125772)
- Testing
- TAXUS Element™ Paclitaxel-Eluting Stent System, Xience PRIME Everolimus-Eluting Stent System
- Where
- India
- Volunteers
- 1,830 people
- Sponsor
- Fortis Escorts Heart Institute
Diabetes
Avoiding Diabetes After Pregnancy Trial in Moms
Mothers with previous gestational diabetes mellitus (GDM) represent a population at higher risk of future Type 2 diabetes mellitus (T2DM), which is preventable through lifestyle modification.
- Trial name
- ADAPT-M (NCT01918345)
- Testing
- Home-based Physical Activity Program with Health Coach, Home-based Low-GI Diet Program with Health Coach
- Where
- 5 sites in Canada
- Volunteers
- 345 people
- Sponsor
- Women's College Hospital
Marijuana Dependence
Effect of Baclofen on Marijuana Withdrawal and Relapse
The purpose of this study is to determine if baclofen dose-dependently decreases marijuana's direct effects and symptoms of marijuana withdrawal and thus decreases marijuana relapse.
- Trial name
- NCT00373295
- Testing
- Baclofen, Marijuana
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Healthy
Effect of Cilostazol on the Pharmacokinetics of Simvastatin
To evaluate the effect of cilostazol on the pharmacokinetics of simvastatin in healthy adult subjects.
- Trial name
- NCT01383395
- Testing
- simvastatin/cilostazol
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Prone Craniotomy, Endotracheal Intubation Fixation
the Effect of Trans-nasal Fixation of Endotracheal Tubes for Prone Ventilation
The aim of this randomized controlled trial is to evaluate the clinical effects of trans-nasal ETT fixation for prone ventilation.
- Trial name
- Trans (NCT05093595)
- Testing
- SFC
- Where
- China
- Volunteers
- 30 people
- Sponsor
- China Medical University, China
Fascia, Trigger Point Pain, Myofascial
Effects of Myofascial Induction Therapy on Pressure Pain and Ankle Range of Motion.
In this study, it will be assessed if there are changes in ankle dorsiflexion and pressure pain after performing the myofascial induction technique in the calf.
- Conditions
- Fascia, Trigger Point Pain, Myofascial, Range of Motion, Pain
- Trial name
- NCT05711745
- Testing
- Calf myofascial technique
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Xerostomia, Diabetes Mellitus
Photobiomodulation In Treatment Of Xerostomia In Type Ii Diabetic Patients
Xerostomia is a major oral health problem that if not recognized and treated can have a significant effect on a patient's quality of life. It leads to difficulties with speech, swallowing and taste alteration.
- Trial name
- NCT06703372
- Testing
- Diode Laser 980 nm, 0.2W
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Hams Hamed Abdelrahman
Heart Failure with Preserved Ejection Fraction, Heart Failure, Diastolic
Impact of Empagliflozin on Functional Capacity in Heart Failure with Preserved Ejection Fraction
Sodium-Glucose Cotransporter-2 (SGLT-2) inhibitors generally and empagliflozin specifically have shown cardiovascular benefits in patients with heart failure (HF), but the underlying mechanisms remain unclear.
- Conditions
- Heart Failure with Preserved Ejection Fraction, Heart Failure, Diastolic, Diabetes Mellitus
- Trial name
- NCT05139472
- Testing
- Empagliflozin 10 MG
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- University of Texas Southwestern Medical Center
Allergic Conjunctivitis
Evaluation of Efficacy of Coadministration of FOV1101-00 and Prednisolone Acetate in Patients With Mild Ongoing Ocular Allergic Inflammation
This is a phase 2 study that will consist of 3 visits during a 3 week period conducted at up to 5 sites. The purpose of this study is to determine how effective the combination of Pred Mild® and FOV1101-00 is compared to either…
- Trial name
- NCT00833495
- Testing
- Prednisolone Acetate 0.12% (Pred Mild®), FOV1101-00, Prednisolone Acetate 1% (Pred Forte®)
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Fovea Pharmaceuticals SA
Dry Eye Disease
Study of INV-102 Ophthalmic Solution in Adults With Moderate to Severe Dry Eye Disease
Phase 2 study to assess the efficacy of topically administered eyedrops of INV-102 during 4-week repeat dosing in subjects with moderate to severe dry eye disease.
- Trial name
- NCT06370039
- Testing
- INV-102, Vehicle
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Invirsa, Inc.
Healthy
Assessment of the Wound Healing Efficacy and Tolerance of a Medical Device on Wounds in Healthy Subjects.
The tested medical device is indicated for the treatment of wounds and small skin injuries. The intention of this study is to evaluate the tolerance and efficacy of the test product by measuring the recovery of the skin barrier…
- Trial name
- NCT04687839
- Testing
- Induction of suction blister, Transepidermal water loss (TEWL), Macrophotography
- Where
- Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Obesity
Improving High School Breakfast Environments
The goals of this intervention study are to implement best practice strategies to expand and promote the school breakfast program and test the impact upon student participation rates among a) all 10th and 11th grade students and…
- Trial name
- breakFAST! (NCT02004977)
- Testing
- Improve access to the school breakfast program
- Where
- United States
- Volunteers
- 904 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Polycystic Ovary Syndrome
Dapagliflozin Efficacy and Action in PCOS
The purpose of this study is to assess the efficacy and safety of dapagliflozin on improving insulin resistance and hyperandrogenemia in obesity women with polycystic ovary syndrome.
- Trial name
- DEAP (NCT04213677)
- Testing
- Dapagliflozin
- Where
- China
- Volunteers
- 165 people
- Sponsor
- Nanfang Hospital, Southern Medical University
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