Clinical trials: Experimental
Brain Infarction, Brain Ischemia
Transcranial Direct Current Stimulation, Improve Functional Motor Recovery, Affected Arm
Overall goal of this study is to determine if transcranial direct current stimulation (tDCS) plus conventional occupational therapy improves functional motor recovery in the affected arm-hand in patients after an acute ischemic…
- Trial name
- NCT01201629
- Testing
- t DC stimulation, tDCStimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Oklahoma
Atopic Dermatitis
Oregano Ointment vs. Standard Treatment for Pediatric Atopic Dermatitis
This study is designed to evaluate and compare the efficacy of 3% oregano extract ointment prepared in aqueous solution versus 1% hydrocortisone ointment, a standard treatment, in decreasing the inflammation associated with mild…
- Trial name
- NCT02289989
- Testing
- Oregano extract cream, Hydrocortisone
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Rutgers, The State University of New Jersey
Hepatitis B
Study of Recombinant Modified Process Hepatitis B Vaccine in Older Adults (V232-059)(COMPLETED)
The purpose of this trial is to determine if there is an improvement in the immune response of older adults over 50 years of age using a modified process hepatitis B vaccine and a currently licensed hepatitis B vaccine…
- Trial name
- NCT00440531
- Testing
- Comparator: RECOMBIVAX HB™ Hepatitis B Vaccine (Recombinant), Comparator: Modified Process Hepatitis B Vaccine (Experimental), Comparator: ENGERIX-B™ (currently licensed product)
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
HIV
A Study to Determine the Safety and Efficacy of Once Daily Raltegravir Compared to Twice Daily Raltegravir (MK-0518-071)
A study to evaluate the safety, tolerability and efficacy of once daily Raltegravir compared to twice daily raltegravir when each is given in combination with TRUVADA™ in treatment-naïve human immunodeficiency virus…
- Trial name
- NCT00745823
- Testing
- Comparator: Raltegravir 400 mg b.i.d., Experimental: Raltegravir 800 mg q.d., TRUVADA™
- Volunteers
- 775 people
- Sponsor
- Merck Sharp & Dohme LLC
Bacterial Infections
Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections
The purpose of this study is to determine whether ceftaroline is effective and safe in the treatment of complicated skin infections in adults.
- Trial name
- NCT00423657
- Testing
- ceftaroline, vancomycin plus aztreonam
- Where
- 54 sites in United States, Argentina and 10 more
- Volunteers
- 680 people
- Sponsor
- Forest Laboratories
Bacterial Infections
Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections
The purpose of this study is to determine whether ceftaroline is effective and safe in the treatment of complicated skin infections in adults.
- Trial name
- cSSSI (NCT00424190)
- Testing
- IV Vancomycin plus IV Aztreonam, Ceftaroline
- Where
- 52 sites in United States, Argentina and 9 more
- Volunteers
- 698 people
- Sponsor
- Forest Laboratories
Bacterial Pneumonia
Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia
The purpose of the study is to determine if the antibiotic ceftaroline is safe and effective in the treatment of community-acquired pneumonia in adults.
- Trial name
- CAP (NCT00509106)
- Testing
- Ceftaroline fosamil for Injection, Ceftriaxone
- Where
- 134 sites in United States, Argentina and 13 more
- Volunteers
- 622 people
- Sponsor
- Forest Laboratories
Relapsing Remitting Multiple Sclerosis
Safety of New Formulation of Glatiramer Acetate
The purpose of this study is to compare pain associated with injections and injection-site reactions of the approved formulation of Glatiramer Acetate (GA) versus investigational formulation of GA.
- Trial name
- Song (NCT00947752)
- Testing
- Glatiramer Acetate, Experimental Glatiramer Acetate
- Volunteers
- 147 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Dentin Sensitivity
Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity
This study will investigate the longitudinal efficacy of two experimental oral rinses containing 1.5% weight/weight (w/w) dipotassium oxalate monohydride (KOX), formulated at pH 4.5 and pH 7 respectively, for the relief of…
- Trial name
- NCT02542943
- Testing
- Experimental Oral Rinse 1, Experimental Oral Rinse 2, Standard fluoride toothpaste
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Atopic Dermatitis
Trial to Determine the Therapeutic Benefit of an OTC Cream on Dry, Itchy Skin of Adults and Children With Eczema
The objective of this 1 week trial is to evaluate the efficacy of an over-the-counter (OTC) 1% colloidal oatmeal skin protectant cream in adults and children with mild to moderate AD.
- Trial name
- NCT02691507
- Testing
- EpiCeram Skin Barrier Emulsion, Experimental Product 1% Colloidal Oatmeal Balm
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Healthy
Dose Response of Intravenous Sincalide(CCK-8) for Gallbladder Emptying
This is a clinical research study to establish normal values for the infusion of a synthetic form of the hormone cholecystokinin(CCK-8) for gallbladder emptying.
- Trial name
- NCT00685477
- Testing
- Experimental Sequence ABC, Experimental Sequence ACB, Experimental Sequence BAC
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Temple University
Atopic Dermatitis (AD)
Tolerance Evaluation of a Nighttime Moisturizing Balm on Babies and Adults With Eczema
The purpose of this 14-day, two phase clinical study is to test the tolerance of a new over-the-counter moisturizing balm on subjects with eczema.
- Trial name
- NCT02357940
- Testing
- Experimental Product
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Hyperglycemia, Postprandial
Investigation of the Glycemic Index of Ethiopian Honey
The purpose of this study is to determine which of the Ethiopian honeys slowly/rapidly raise the blood glucose level.
- Trial name
- NCT02488018
- Testing
- Provision of experimental honey
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Addis Ababa University
Cerebral Palsy
Data Acquisition Study for a Communication Device for Pediatric Patients With Cerebral Palsy
The purpose of this study is to evaluate a touch screen application designed to help pediatric patients with cerebral palsy communicate.
- Trial name
- NCT02242994
- Testing
- Dynavox Maestro, Experimental App
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Axel Krieger
Erythema, Edema
Repeated Insult Patch Test of Personal Lubricants
Determine the ability of the study material (personal lubricant) to cause sensitization by repeated topical application to the skin of humans under controlled patch test conditions.
- Trial name
- NCT02297841
- Testing
- Experimental: Novel lubricant Miami Fragrance, Experimental: Novel lubricant Miami no Fragrance, KY Liquid lubricant
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Healthy Volunteers
Effect of Three Fibres on Glycaemic and Insulinaemic Responses in Healthy Adult Volunteers
The purpose of this study is to determine whether DuPont Experimental Dietary Fibre products 1 and 2 are digested using glycaemic and insulinaemic response as markers.
- Trial name
- NCT02701270
- Testing
- Experimental Dietary Fibre 1, Experimental Dietary Fibre 2, Polydextrose
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Danisco
Parkinson's Disease, Depression
SAM-e for the Treatment of Depression in Patients With Parkinson's Disease
This study will test a chemical called s-adenosyl-methionine (SAM-e) for the treatment of depression in patients with Parkinson's disease (PD).
- Trial name
- NCT00070941
- Testing
- SAM-e, oral escitalopram
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- NYU Langone Health
Spontaneous Bacterial Peritonitis
A Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis
Spontaneous bacterial peritonitis (SBP) is a common and frequently fatal complication of end-stage liver disease with a mortality of up to 10% primarily due to the development of kidney failure.
- Trial name
- NCT02528097
- Testing
- Standard Care, Experimental
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- NYU Langone Health
Respiratory Insufficiency
Assessment of an Endotracheal Tube Securement Device
Endotracheal intubation is the translaryngeal placement of a tube into the trachea via the nose or mouth. Endotracheal tubes must be securely fixed to prevent movement, which may result in accidental slippage of the tube into a…
- Trial name
- NCT01651260
- Testing
- Experimental ET Tube Securement Device
- Where
- 5 sites in United States
- Volunteers
- 65 people
- Sponsor
- Hollister Incorporated
Asthma, Children
Efficacy and Safety of Increasing Doses of Inhaled Albuterol in Children With Acute Wheezing Episodes
Metered dose inhalers with spacers are devices capable of providing higher rates of lung deposition of drugs such as beta agonists when compared to conventional nebulizers, but there is no consensus about the optimal dose when…
- Trial name
- NCT01323010
- Testing
- Albuterol - Experimental, Albuterol - Control
- Where
- Brazil
- Volunteers
- 119 people
- Sponsor
- University of Sao Paulo